6 DHT Blockers For Men Ranked (Worst to Best!)
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- čas přidán 11. 06. 2024
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When I was diagnosed with male pattern hair loss 10+ years ago, I felt overwhelmed trying to decide which DHT blockers (if any) I should use.
Which DHT blockers work? Which ones put me at risk of side effects? What does the real evidence say versus marketing hype for the latest DHT-reducing supplement, topical, or drug? The answers may surprise you.
Today, as a medical editor, I'm making this video so you can get to the facts (not fiction) about DHT reducers. This way, you can bypass all of the misinformation online, avoid my treatment mistakes, and uncover which DHT block actually work (and which ones are a waste of money).
Specifically, we're going to evaluate 6 DHT blockers in terms of their POWER versus SAFETY profiles. This is, in my opinion, the best way to organize this information.... so you can climb up (or down) the ladder depending on your needs and preferences.
Despite what marketers lead us to believe, effective DHT reducers (natural or conventional) don't need to cost a lot of money. But some "natural" options may not be as safe as we think.
So, spend some time educating yourself on lowering DHT! I hope this video helps you get started.
//Get A Free Course On Achieving Hair Regrowth, With Or Without Drugs//
perfecthairhealth.com/email-c...
0:00 - Intro
1:05 - Lowering DHT: Power Vs. Safety
3:43 - DHT Blocker #1 (Natural)
6:56 - DHT Blocker #2 (Prescription)
8:38 - DHT Blocker #3 (Natural)
12:09 - DHT Blocker #4 (Prescription)
16:04 - DHT Blocker #5 (Prescription)
17:08 - DHT Blocker #6 (Prescription)
18:42 - Final Thoughts
About Rob English:
-Editorial board member of Dermatology and Therapy
-Medical editor specializing in hair loss disorders
-Peer-reviewed publications: perfecthairhealth.com/publica...
1. Saw palmetto (320mg daily in 2 doses)
2. Ketoconazole shampoo 2%
3. Herbal extracts (zinc etc)
4. Topical finasteride 1%
5. Oral finasteride
6. Oral Dutasteride
7. Derma roller
8. Minoxidil
@@chrissullivan40 not a DHT Blocker
1 is the best and 6 is the worst or vice versa?
@@returnedtomonkey8886 1 is worst and 6 best…. according to the Video maker
I've experienced significant hair loss issues. I tested many hair serums. The trending ones and the products that influencers endorse, however none looks to work. The special wedding day is in 4 months and I was concerned a lot because my hair wasn’t looking good. I've came through this hair growth serum by reactivate littleexrta and I have been using it for the past month. I’ve noticed positive results, My hair is growing faster & Hairfall has lessened. Also, some white hairs have begun to turn black. I've apply it daily. It’s a necessary recommend serum for everyone who deals with hair loss.
Men are mostly affected by Androgenic Alopecia - So nothing really beats Finasteride/ Minoxidil combo with Microneedling.
Anagain, Procapil, Baicapil, Capixyl, Redensyl etc. can help, but NOT to that extent.
My hair feels thicker, looks more denser, and I'm even observing new growth along my hairline since I started using reactivate hair serum.
Hey spam bot 👋
don't believe this it's a scam
Total scam. Reactivate little extra is not at all useful!
Get a free course on strategies for hair regrowth, naturally and conventionally: perfecthairhealth.com/email-course/
Wow, finally a video where someone isn't bullshitting that TF is devoid of side effects! Great video!
Keep the awesome videos coming, Rob! Love the new CZcams channel!
Perfect Hair Health thanks for this amazing knowledge about hair loss.
I already asked this question in one of your videos, may I know what is your current hair loss regiment?
Thanks again
Very well researched to prevent confusion.
This is a 🔥 video. Ranking them?! That’s crazy! More CZcamsrs should do this. So creative
This presentation format is very good. Thank you for the concise and well presented content. :)
Rob, you are the best! Brutally honest and rigorously scientific.
I have been taking oral finasteride 1mg per day for over 2 years now. Zero side effects. My only regret is I wish I had started taking it much sooner than I did. When I purchased the first bottle I kept it in the cabinet for about 6 months too afraid to take a pill thinking it would destroy my life, reading all the others stories about side effects. Looking at the actual studies, reported side effects are about 2 percent which was the same as that experienced by the placibo group. So I started taking it and have never had an issue. It has stabilized my hair.
Does it really have the chance to make you impotent? That's the scary part for me
How old are you ?
@@user-dn7du7fp4j I am 60 years old.
@@jamest681 no offense, but at the age of sixty, the body's DHT levels are low anyway, so your situation sir, is not comparable to someone in his 20s
@@gergelyzoltan8422 Actually, as men get older they become more sensitive to DHT than someone who is younger. That's why as men get older they are more likely to have hair loss even though DHT levels are less. In that sense, finasteride proves to be even more effective in my case as it has stopped hair loss. As far as side effects, a billion dollars worth of double blind studies since the drug was introduced has shown consistently that about 2 percent experience side effects, which was the same as the placebo group experienced, so the drug is very safe. For those who do unfortunately experience side effects the studies also show that the vast majority stop experiencing the side effects once the drug is stopped. The side effects in most cases are mild as well. That is why it is important to speak to your doctor and not get your information from 3rd party stories from the internet.
Hey rob! Great content as always.
I'd like to ask your opinion on PRP and GFC hair treatments and know how effective those are for hair loss
Watch his video: 5 secrets the hair loss industry doesn't want you to know.
This will answer all your questions
Hey Rob, what is your thoughts on stinging Nettle Root? Thank you for making such wonderful videos.
These side effects matter to guys more than the medical establishment realizes. A good friend of mine was taking Dutasteride for prostate enlargement issues and started growing breasts. Dropped it and said he’d rather use a catheter to pee.
im fucking deaddddd 🤣
lmao@@lemurienconstricteur1745
That's what happens when people chemically castrate themselves.
Amazing video! Greetings from Brazil!!
Thanks Rob, great info as usual
Thanks for sharing this information with us
But I have a question, what about pumpkin seed oil? I heard that it helps also against DHT
Man, I got into hair loss treatments 13 years ago when I discovered I was losing hair. Had severe side effects from fin and decided to just let it go. I see now that after all this time nothing has changed at all. Same treatments, same problems.
Have you checked out our video on topical finasteride? It might help with the tolerability issues you experienced - especially at exposure volumes of 0.1 mg daily.
czcams.com/video/NuX3vEq2Mao/video.html
I'm sorry to hear about your experience with both drugs.
@@PerfectHairHealth Why don't you ever talk about topical dutasteride or dutasteride mesotherapy? Topically many people report that dutasteride does not pass as easily into serum and affect body system as easily as topical finasteride. Many can't tolerate fin. Lots of clinics in Spain offer Dutasteride mesotherapy, plus is you only need to get it once a month, and for topical dut - once a week because of long half life of 4/5 weeks..
Would love to hear your thoughts on the matter!
@@asdfasdf8368 but its very expensive...
Get a hair system. That's the ultimate solution besides hair cloning.
@@lexi6081 Hair system is not a solution as it’s not your real hair that actually grows on your head. There always be the anxieties in the back of you mind if people notice it or whether it’ll come off.
Very informative and helpful
Very useful video for me
Simply detail explanation
Thanks a lot ❤
This is the best channel for hair loss
I don't want hair Loss
To cure hair loss*
True
This is obvious
There is nothing on this channel you can’t get on google in 5 minutes
Hey Rob,
This video is perfectly structured and addresses the same concerns many of us share. Two questions.
1. Would any of the alternative natural DHT blockers compete with Saw Palmetto? I'd be interested in seeing a video on the ones not covered in this video, unless they are all "F".
2. Can an SSRI such as Prozac cause hair loss (not in the short term but while on it long term)?
it doesn't seem like you'll get an answer to this, i'd reccomend you just read some actual studies (not articles) about these things.
Yeah, go ask your doctor
your anti depressant wont cause hair loss. I also talked that with my doctor
Brilliant video. So glad i found it.
Thank you very much for this information.
crazy informative. thank you!
Thanks!
Noticed my hair thinning in May 2023, and by July I can see more of my scalp mainly the front and top. Can’t pinpoint if it’s TE or something else. No genetic reason. I had a stressful family event last fall. It’s still a lingering stress. Got on minoxidil a week ago. Started microneedling today. Getting on nutrafol tomorrow 😅. And seeing my dermatologist next month to get a full bloodwork analysis etc done. I said all this because as stressful and near to tears I am about this sudden hair loss, your channel really helps keep me informed and somehow I feel comforted. So thank you. So much.
Bro same 😢
Consider taking rosemary oil, it will work like charm
Updates ??
Bro same and I'm only 24 yo , I can see bald spots on top of my head I started wearing a hat to avoid the wind because my hair got too thin . Can you provide any update on your situation please , what works and what it doesn't work ?
@@bimmer1110massaged into scalp or oral?
Some people have found that the Edgar Cayce (a medical intuitive from the early'ish 1900's) advice of crude/unrefined Pennsylvania "sweet" crude oil occasionally applied to the scalp helps to stop hair loss and boost growth.
That may well be but that doesn't take the balding gene out of your genetic code
Can you do a video on magnesium oil and hair regrowth from removing calcification
Ive been using Nizoral ketoconazole with minoxidil and a dermaroller and I've seen great results
Was there a reason why you didn’t go on to finasteride?
Update on results? I’m planning on going on this exact routine
THAT WAS A GOOD VIDEO PRODUCTION
Great content Rob you are an hero in this field and pretty sure you drove me to avoid all the "natural useless" solution and simply go talk to my dermatologist. since mid september I am on minoxidil and finasteride , microneed 1 per week, soon I will start to use an electric scalp massager. Starting to see improvements.
One doubt: can you inquire more about "man who can t produce dht never go bald"? Isn't this a confirmation that dht6 is the cause (not a correlated phenomenon) of Alopecia?
The best piece of information for me in this video is that more than 320 mg of saw palmetto extract is the maximum useful daily amount.
Another excellent, reasonable and level-headed video Rob!
Just wondering what is *your* current hair loss protocol?
Are you administering any topicals, orals, doing massages, etc.?
Your hair looks immaculate and I remember in one of your very first CZcams videos you mentioned that you stopped the massages, so I was wondering how are you maintaining this lion's mane?
Thanks!
Thank you! Currently, I'm still employing stimulation-based therapies (microneedling, massaging, etc.) - albeit less consistently than in the past. No topicals, oral supplements, medications, or devices. I mentioned this in another comment below, but because my time is so constricted today versus when I started doing these interventions 7+ years ago, I'm also considering beginning a DHT reducer in the next few months. I'll be sure to make a video about my protocol soon!
@@PerfectHairHealth Thanks for the thorough reply Rob! It would extremely interesting to see what DHT inhibitor you would select for your own protocol and at what dosage/administration frequency, please keep us posted!
I had the same question. My hair is great now and I am 45, so what should i take a dht blocker to prepare for the future? I am a little concerned of the side effect in terms of low T delivery
In Europe and South America, they have finasteride Scalp INJECTION. it’s works really well, and no. Affect in blood DHT. Do the USA have that???
@@jordilobon7528 My opinion: i would wait until the first CLEAR signs of MPB before starting. Some men never have it...
Does topical Dutrasteride exist? If so, i would like to have heard safety comparison with oral version. Good review though
Any chance to know what best product of saw palmetto to buy ? that doesnt exceed the 320 mg dose?
Your videos are so informative!
Why you don't make them any more?
The bald police arrested him
oral finestride and 5% monoxidyl definitely showed some improvement after 3-6 months (if taken/ applied daily) - however - the side affects hit me early on (1-3 weeks) and it was really disappointing as it does not affect all users - tiredness / aches and pains / and worse of all memory issues and depression .... it may work for you but it really does come at a high risk from my experience. Id rather have energy no aches and pains and a good memory and not be depressed than a head of hair.
There is also a small chance of prostate cancer, which defeats the purpose of finasteride if one has to go through chemo treatments.
Within a week u got side effects??! I sure it ain’t a placebo effect
@@Mr.Majestic77 stop spreading false informations like this !
@@robert4716 that is not false information. Please do your research before making comments.
@@Mr.Majestic77 show us the study that proves it causes cancer
I take stinging nettle root,I make a tincture from it also small Willow herb that I dry to make tea,they are also good to slow prostate grown.I grow them in my garden.
Great info, thanks
I don't know why, but the whole project, starting from website and ending with production of this video, reminds me of tv commercials, which usually I distrust. It could be only me, I don't know.
Anyway, the content is great. Thank you so much for it!
I think the majority of people who worry about Finasteride/Dutasteride side effects get spooked off too soon. When I first started taking Fin I had a side effect twice early on & then never again. For those who worry about sides I would take the doses for at least a good month before throwing in the towel. Of course if you're having bad side effects constantly I would stop also but I think too often people let one sign of a side effect scare them off when it wasn't going to end up being a normal occurence
I felt shy and depressed on it. It felt like immaculated or something. I had a terrible time in the gym. This was just the topical form too.
Finsteride definitely give side effects. I have got reduced libido greatly and no more morning woods and depression sometimes.
See my comment. You'll think otherwise.
Is propecia or finasteride cheaper?
What kind of side affects
One day hair loss will be prevented - its a strange process, ive noticed sensations in the pattern baldness areas that feel like burning - the sensation comes and goes and ive noticed it generally marks the start of further loss and receding in the area. Also, and this has been documented the actual thickness of scalp skin reduces in balding areas plus when i get goosebumps they only happen with any strength in the side areas of the scalp. Anyone else noticed any of these things?
Definitely felt it. My pinnacle was when I cut my hair really short, then used shampoo to thoroughly clean my hair and scalp. After that I could not stand being outside as my scalp felt like it constricted my skull and it was also super dry. Now after doing massages, using lard and oils, and having a longer hairstyle, I don't feel that burning feeling anymore.
@@zeAmateur have you managed to stabilise your hair loss?
@@JD-fr7rm I have a bit more hair density than last year so I believe it's stable for now. Nevertheless, my scalp is less itchy and has less dandruff than before
@@zeAmateur you took finestride?
@@JD-fr7rm no
Keto shampoo script also has sulfates?
Worth it still? Or to use it couple times per week?
I am planning to get palmetto berries. What is the best way to use them? I could grind them and eat them like that or make a decoction? I am a female. Thank you.
What about topical caffeine?? Are the studies true about it being about as good minoxidil??
New subscriber. Love your videos. Are you gonna make some videos about head massages?
Thanks Marko! We've got a whole video series about scalp massages inside of our membership community. Aside from that, we published a study about massaging (including a demonstration video - which you can find in the supplementary materials) here: link.springer.com/article/10.1007/s13555-019-0281-6
Would a topical version of saw palmetto be as effective as the oral version, without the side effect profile?
Saw Palmetto is truly magical i even noticed the oil production got lower but however low DHT causes some other things.I have noticed my muscle growth slowed down , i got itching on certain areas and back pain.
Would it have any side effects on testosterone or TRT?
Also, another topic: is it normal to have prescribed topical minoxidil (1 per day), oral regexidil/ minoxidil (1 per day) and duta/finasteride (1,5 mg per week in total) ?
Wtf man that sounds dangerous be aware of possible side effects and stop if needed, trust me on this
Great video, can you do a video on topical dutastaride?
Yes! We are working on a systematic review about this and, once it's published, we'll make an in-depth video covering every aspect of this
You say 0.2 is enough for blood saturation of propecia.
My doctor has me taking 1mg every Monday Wednesday and Thursday to help my testosterone. Is it better to take 1mg 3x a week or daily 0.2 for increasing T and still helping my hairline?
I have 2 questions for you , please answer
Do you have any patients who managed to keep their hair and even regrow with only your scalp massages for more than 3 years?
And it s true that the mom s gene is more important when it comes to hair ? My dad at my age was receding more than me . Is there chances i don t have his gene ? Thank you , Rob !
Since the mechanisms behind massaging and microneedling are suspected to more so target tissue remodeling (i.e., angiogenesis and fibrosis attenuation) in addition to the stimulation of growth factors / signaling proteins that initiate anagen (i.e., the growth phase of the hair cycle), I'm inclined to believe that people with long-term adherence to microneedling / massaging have an easier time holding onto results. We've seen this reported by some members of our community, and there's also evidence in studies of this happening. For instance, a study on minoxidil vs. microneedling vs. microneedling + minoxidil showed that 6 months after quitting all treatments, nearly all of the participants using minoxidil lost their hair gains while nearly all of those who had done microneedling or microneedling + minoxidil held onto their hair gains.
In terms of genes, there appear to be at least 220 genes associated with hair cycling and/or androgenic alopecia. To my knowledge, there's no clear evidence of baldness being more inherited by one parent versus the other.
I took finesteride for almost 20 years starting in my mid 30s due to baseline elevated PSA. I didn't get side effects until 12-15 years later. When I stopped at just under 20 years, the side effects had gotten really bad. Unfortunately several years later, they never reversed. I would highly caution anyone from using this drug if they care about their sexual health.
Thats what i needed to hear thank you!
Im 17 suffering from the early stages of male pattern baldness and i already use minoxidil and now a derma Roller, I started questioning if i should start with FIn as well with the intention to just stop when or if the side effects kick in since i thought they would stop if i simply stop (would go bald if that happens but who cares)
Now that i know that even if i stop using it it can affect my body its a big no no
Hey, what was your dosage?
@@smoothcriminal4618losing hair so young is just bad. There 's not much you can do.
If you took it for 20 years it means you are now in your 50's. In your 50's it is normal for men to have loss of libido, sex drive and even ED. It is pretty common
doesn't make any sense, you are 50 it's normal for that to happen if you aren't really healthy and eat in a certain way to works for you, you should go to a functional doctor
Great video Rob.
Can you please share that with what ratio I can mix finasteride tablet with topical minoxidil?
As far as I'm aware, beta-sitosterol is the main active substance in both saw palmetto and nettle root extracts.
Rob, this is a DHT video but I need to ask you about oral minoxidil. I've read your article about it. You've mention 2.5 mg as a sweet spot for oral minoxidil dose if one want maximum results with minimum side effects for hair regrowth. Thing is I'm not old but not only do I have progressive AGA (though I still pass off as not bald) but also I'm a severe hypertensive patient, BP ranging anywhere between 150/100 to 180/140 if I don't watch my diet or exercise and if I don't take my drugs. And now I'm thinking if I'm taking blood pressure medication anyways why not try oral minoxidil? It will address both of my issues. Sorry for the long text and for wanting free advice but please suggest me WHAT WOULD BE MY SWEET SPOT DOSE FOR ORAL MINOXIDIL? I consider you to be the best and no. 1 source for hair loss information. Thanks in advance! 🙏
Europe and South America has micro injections of finasteride in the scalp, BLOOD work shows no change in the blood DHT levels at all. And u only need ONCE A MONTH Micro injection
@@conradofmc_ny6706 wtf? Where the fuck can I do this shit?!
@@karkkimarkkinat2109 I don’t know man that’s crazy right
Oral minoxidil is quite potent, affecting the heartbeat. For hair benefits, it is being prescribed off-label with a tiny fraction to start with. I would start with a very tiny bite off the tablet and get used to it for a few days, and then assess how much will work for you. Everyone responds differently in different doses. Tinker with it yourself and see what works the best for you. But, always start very tiny to acclimate your body.
I am from India, I want to send you money for your service. I don’t have much but I want to show my gratitude for the objective knowledge you render.
nice or scam?
Question for you Sir, I have a supplement with standarized 160 mg saw palmetto (85% fatty acid), also has 120 mg of pumpkinseed oil. should I still take two of those or just 1?
Bro what are you taking currently for your hair ..? Pls share the valuable info which will help many ✨
I have used both oral finasteride and oral dutasteride. The dutasteride works great, but it has a detrimental effect on a condition I have called "essential tremor" - it increases the tremor in my hands after continuous use. This makes it undesirable in my case, and I have to revert to finasteride, which is less effective but doesn't affect my tremor.
It reduces dopaminergic signalling by a lot, don't use that, man.
That’s called Ebola not a tremor
For years, I tried most everything on this list and a few things that weren't including minoxidil and a laser helmet (anyone want to buy it cheap?) Then I accidently discovered what worked for me- or actually my wife did. After I moved to the Philippines and married her, she started washing my hair with a native product with somethin in it called gugo bark, from a vine that grows here. After 6 months I had a full head of hair, the first time in 20 years. I buy a 1 liter bottle of it here, which lasts several months for about $7.00
Hi Paul. I’m a woman with hair loss problems. What would be the name of that shampoo brand? I’m feeling hopeless over here. 😢
@@deedee2218 Daiia. Best wishes!
Can this be bought at like Watson's type of shops?
So... And what about Pygeum? Is this as effective as finasteride? I heard it's pretty effective - somewhere between Saw Palmetto and Finasteride without side effects. Am I right?
MY BRUTALLY HONEST EXPERIENCE WITH FINASTERIDE
I started losing my hair (around my temple area) as a 23 year old. I panicked and ordered oral Finnasteride (1mg) and started taking it daily to prevent more hair loss... at the time i was thinking "2% chance to get side effects? Pff no chance it will happen to me!"
*famous last words*
I immediately started having side effects. The first week i developed the famous ball pain and some other side effects like pain when finishing the deed... "if thats it, its not thay bad!" I thought...
2nd week, my small (existing) gyno on my left nipple got 3 times bigger and developed gyno on my right nipple (which i didnt have prior)... i am a natuarally a muscular guy with a really big chest, so i legit started looking like i have fucking breasts... at that point i was reslly having doubts, but i persistent (bcs i was still scared of losing my hair)
Month 2... bye bye libido... bye bye morning wood... bye bye sex life... hello 👋 insecurities!
At this point i freaked the fk out. I didnt even think about sex once for a week straight (and as a 23 year old in a relationship with a girl thats a 10/10, thats a no go...) I literally lost complete interest in sex... I had never ever thought this is even possible...
I stopped it 3 days ago and im starting to gain my libido back (thank god). The painful balls went away and my soft sausage is slowly starting to harden (lmao sorry for the analogies, trying to be pg12 hahaha).
So now, im left with man boobs, 4 months worth of finasteride which im never gonna touch... more insecurities, still gonna lose my hair... but hey...
Id rather be bald than lose my libido. I never realised how important this is for your mental health!
Also, there is no frrigging way in hell theres ONLY 2% chance of you getting side effects. Look at this logic:
1: Pharmacies make BANK from insecure men. Youd be surprised how desperation can make you take crazy risks (its in their favour to lie about the low percent of side effects bcs they PROFIT BIG TIME!!)
2: How the FK are you not gonna get sexual side effects when literally 70/80% of your dht (your sex hormone) is being cut overnight!!! Statistically It makes NO SENSE
So guys, if youre feeling insecure rn, just know you ARE worth it no matter fucking what ok? Your health is WAY more important.
P.s. if finasteride works for you, good for you broski! But if youre experiencing side effects, i wouldnt risk getting pernament side effects.
Have a lovely day brothers!
Used it for a month and started losing libido but thankgod hair transplant in my country is relatively cheap
Similar thing happened to me, I was 19yo, I was forcing myself to **** my girlfriend cause I really had lost libido and my sword didn’t get 100% hard, only like 90%. I rather go bald.
"guys statistically it doesn't make sense, but let's take my anecdotal experience rather than the actual meta analysis of studies and actual stats of % chances of side effects" lmfao
@@zainab972 you might as well not even waste your money on a hair transplant if you're not willing to do medical treatment lol
@@e47kz yeah trust blindly the studies financed by the pharmaceutical company that sells the medicines
Is it possible to do other things that prevent the likelyhood of being affected by Finasteride side effects? I am thinking that having a poor diet, lacking nutrients and minerals and poor lifestyle would increase the odds of the having bad side effects and doing the opposite would give me some room to be protected of them.
Another option is taking both beta sisterol and pumpkin oil seed capsules together so it'll block dht directly on the scalp without damage the free testosterone
Can you explain more please
Great video. What are your thoughts on combining saw palmetto or other herbal remedies with the more powerful pharmaceuticals? Synergistic effect, or unnecessary and waste of money?
I've also heard the GLA in borage seed oil or evening primrose oil can also help. Any info on this?
It's a great question, and one that isn't easily answered without data. Technically, saw palmetto and finasteride target to inhibit type II 5-alpha reductase through similar mechanisms. However, saw palmetto also seems to inhibit type I 5-alpha reductase and decrease androgen receptor binding in certain tissues. So, you might get a little extra benefit by combining finasteride with saw palmetto. perfecthairhealth.com/saw-palmetto-for-hair-growth/
We've got some articles / videos coming out about borage seed oil and evening primrose oil. So I'll keep you posted!
@@PerfectHairHealth awesome! Thank you for the reply and your insight! Looking forward to that!
@@samueljbeckett Of course! Thanks for watching.
Very informative
Is it ok to swallow Finasteride tablets with carbonated water? Can it affect the absorbtion?
A hair restoration place I visited here has started doing treatments where they inject a dutasteride based product directly into the scalp. Just wondering if you’ve heard anything about this or the effectiveness of it
Yes! That’s mesotherapy dutasteride. We just released a guide about this. What’s the clinic called?
@@PerfectHairHealth it’s called Kaloni, they’re a hair transplant clinic in Mexico. I believe I was quoted about $300 or $400 USD for it.
FINALLY
THE HAIR LOSS TIER LIST
SHUT UP BARACK
Im considering using minoxidil in junction with the massages for a period of 6 to 9 months. However I gotta ask, would stopping minoxidil after that time but keeping up with the massages prevent any hair gains from falling out?
What’s DHT Blocker effect on beard and facial hair ?
Be cautious with Avodart (Dutasteride). Recent studies have shown links to severe depression. I myself had horrible side effects with this drug.I did get much better hair growth with it, but it isn't worth the side effects. Now I'm with finasteride and while it is not as effective I'm not getting side effects from it
I know it fucked me up too
put the link of that study please
I got muscle twitches from it. It was awful. I could feel my shoulders and upper arms twitching all the time. I dropped down to Finasteride and it's fine.
+ I am not convinced taking this stuff long term does your brain any good...I wonder if in 10-20+ years time they find an increase in alzheimers or something? How scary would that be?
@@elio3232 For some reason my comments are getting deleted every time i try to link it
@@alnm951canyou read my comments
I’m on oral finasteride and I’m curious if you can use the topical along with the oral medication?
What do you think of Hairmax Shampoo and DHT Blocker vitamins? Am i wasting my money with these?
Do you put somewhere studies to back your claims about nautral DHT blockers? And do you have any strenght list of each natural DHT blocker? Plus also as I research zinc or EGCG (green tea catechin) they both mostly inhibit type 1 5-AR, not type 2 so that makes them slighly useless for AGA.
Exactly I couldn’t even use the green tea it almost made it worst but one DHT blocker that is congruently effective for my diaspora is astaxanthin
@@MrSimsEffectwhat type of astaxanthin?
I'm on my second month using dutasteride and I can tell you that it has a much better cost benefits than finasteride. In just two months I already see good results on my hair and with less side effects than when I took finasteride. Actually I had no side effects until now. The good thing about dutasteride is that it increases the testosterone leves by up to 23% according to researchs.
When I took finasteride it took 6 months to show the same results as I am now in two months with dutasteride. Let's see the outcome in the next months regarding results and possible side effects. I'm optimistic regarding that.
What is your dosage for dutasteride?
@@dindin.skully 0,5 mg/day. The standard dose.
it also increases estrogen levels lol
@@e47kzsure 😆
Is that oral or topical?
How to take 0.2mg of finasteride? Should we take once in 5 days or break it and consume?
great video. other sources cofirm this as correct
Great Video Rob.
I have one Question. There are multiple studies on topical finasteride that suggest the same systemic dht inhibition as oral finasteride. As far as I know, there is only one study that suggest a low systemic inhibition with a low dose of topical Fin. However this study only went on for a week and we know that finasteride accumulates in the body, which makes it very likely that even the small dose would reach 70% inhibition at some point.
So why should topical finasteride reduce side effects by 30-50%?
Thank you.
I'm using a topical formulation of 5% minoxidil with 1% finasteride. I'm not naming the product as I don't want this to come off as an advert. You can Google the above combination and find a brand that is available in your country.
This is a great question. These estimations are partly deduced from (1) clinicians who've been prescribing topical finasteride over 2+ year periods and receiving patient feedback, and (2) a slightly less dramatic reduction in circulating DHT with the topical versus oral formulations over months-long trials, which seems to correspond with a reduced risk of side effects. On that note, there was an unpublished clinical trial (by Dr. Chiara Insalaco) of 300 men administering topical liposomal finasteride daily for 18 months. There were no reported sexual or cognitive side effects, and DHT only decreased by 7% (which is biologically insignificant). The data were presented at a conference and did not undergo peer review (or publication), which makes me hesitant to fully trust the information. Nonetheless, there are topical formulations that may help us maximize skin penetration and minimize systemic absorption.
@@PerfectHairHealth thank you for your answer.
Is it possible to get this 0,1 % liposomal finasteride? I'm currently looking into finasteride and try to choose between oral and topical.
In Europe and South America, they have finasteride Scalp INJECTION. it’s works really well, and no. Affect in blood DHT. Do the USA have that???
What is your regemin? And I'm certain topical fin quickly goes systemic. I've tried it several times and feel like absolute crap and moody approx 8 hours after applying it. Its not placebo either trust me.
been using apple cider vinegar with onion garlic extract reishi and turmeric, so far looks good, i also use medicinal mushrooms and drink sencha green tea.
how are you doing now?
All that for nothing smh…
what do you think about the approach to hair loss from danny roddy and, or ray peat ?
I got my gyno removed. Would it come back if I take fin? The doc remove the whole gland
Hey Rob , my question is a bit irrelevant to DHT reducers and I'd really appreciate it if you could answer it. I got the Pfizer vaccine the other day and since then I have been shedding a lot of hair. I also have muscle pain to my whole body. It's tolerable but it's annoying. My two inquiries are :
1) Is there a logical explanation for the hair shedding?
2) Is there any study that prove that the Pfizer MRNA vaccine is safe? I know they got approved very quickly since it was an emergency so there is not a of lot clinical data , but I'm scared for long term side effects and to be honest I started regretting that I got the shot.
Thanks in advance :)
I was just thinking of asking this same question because robs research abilities are second to none 👌🏼
@@christinemarin5450 Why would you get a untested vaccine put in your body for something that is no worse than the flu?
@@beyondtarotandmore4723 Because that person is an idiot who happens to have a penchant for gambling with their life, lol
@@cdtpal3061 You do realize that your body has this thing called an immune system. Something specifically designed to kill off viruses like such. No if you are health compromised, that is a different story.
@@MattFischy you do realize that most people who got Johnson and Johnson and astrazeneca vaccines have had worse symptoms than covid? More power to you if you want the vaccine. Just don't leave behind your face diaper
I was taking oral finasteride and developed a worsening in my anxiety pretty quickly. Stopped it and switched to topical a few weeks later. The topical didn't give me side effects for quite some time, but I think around 3 months in (maybe less) i started experiencing sexual side effects. Low sex drive and just wouldn't stay as hard with my girlfriend. Ditched the finasteride, ditched the girlfriend, hopefully not ditching my hair for a few more years 😂
Interesting story, bro! Tell me, please, what dose of topical fin and oral did you take? Did your libido come back after you quit finasteride? Have you taken other medications or vitamins, maybe minoxidil or zink? I will be grateful, if you answer 🙂
@@ZagadochnyPrince ❤
@@ZagadochnyPrince i took a very low dose. Don't remember exact, but i was cutting pills into 4ths.
I used the Hims topical spray. Once i stopped using it i was back to normal.
I took oral finasteride for not even 5 days and it was giving me the worst anxiety I’ve had in my life! It almost gave me an anxiety attack during a college class, out of absolute nowhere. The feeling was close to a sense of doom, it was absolutely awful. I notified my doctor and he took me off of it immediately. I haven’t had any sort of anxiety like it before. It also made my tinnitus louder, and gave me bad headaches (I never get headaches) Luckily I was able to get a refund but I am sticking to topical minoxidil for now. Works pretty good.
Yeah im not gunna take it
What to take as a substitute tho?
@perfect hair health where can we find topical finasteride.? not the combo with minoxidil, just finasteride.
Hi Rob - what literature do you have on the optimal Dutasteride dose to use topically to optimise results without suppressing DHT systemically too much? Loved your breakdown of finasteride dosing and suppression versus results 🙌
We're working on a literature review about this! Anecdotally, we've seen that 4-6mg/week of dutasteride topically seems to have very little influence over serum DHT levels, at least for most people. Higher than that amount, and we get a lot more heterogeneity in the data. Some people still see no serum DHT changes even at 30+ mg per week, while others see a complete nuking of serum DHT. The bigger question (for me) is efficacy. There's a big topical dutasteride study that is near publication and we hope to have more info then.
You probably don't want to block DHT since it is a very necessary molecule. What we need is something that will make hair follicles less sensitive to DHT.
A topical antiandrogen - like Flutimide or Topilutamide 🙇👌
@@jamescalifornia2964any recommended products that work best for hair loss? Thanks
Thoughts on the safety and efficacy of oral minoxidil? (1.25mg to 2.5mg).
Terrible risk to return. Just do finasteride and topical monoxidil
I do 5mg twice a day. No sides.
safe and efficacious
Moon round face ugly as sin
I use a shampoo with saw Palmentto caffeine and ginseng does it will block my DHT?
Hey Please help, I'm 22
I'm using Commercial shampoo from childhood and whenever i try sls parabens free shampoo my hair starts falling. Now I want to try Ketoconazol shampoo, should I go for it ?
As a androgenetic alopecia (AA) sufferer of over 30 years, I would dissuade anyone from using nonpharmaceutical solutions: they may be safer, but their real effectiveness is nil. Regarding the pharmaceuticals, the path should be finasteride-->dutasteride-->? (I'm assuming everyone will be on minoxidil simultaneously). I show a question mark because most AA patients will experience a decline in effectiveness of even the best anti-DHT medications over time. After treatment for 20 years or more, most of us will be at a loss of what to do next. More research is desperately needed.
This is great advice. The problem with all natural interventions is that they lack long-term data. That doesn't necessarily mean that we should confuse the absence of evidence as evidence against those interventions, but we have to keep in mind the "known knowns" when navigating treatment options. For some people, natural DHT reducers work well enough to stave off AGA progression - at least in the short-to-medium term. But what about 5 years down the line? Or 10 years? We don't yet know, because the clinical studies don't yet exist (and they may never exist).
There is also the phenomenon of waning treatment efficacy in some people on long-term 5-alpha reductase inhibitors. It doesn't happen to everyone, but it happens enough to suggest that other mechanisms end up taking over in AGA outside of 5-AR activity, or (just as likely) that endogenous factors begin regulating those drugs' efficacy long-term - such as the case with androgen deprivation (AD) and prostate cancer (where AD, over time, becomes ineffective). I agree that we desperately need more research.
@@PerfectHairHealth bruh,help.....
... but Lower DHT also leads to - increased bodyfat, lower strength, lower bone density, lower positive emotions, increased blood pressure, less flexible blood vessels, increased anxiety and depression, increased chance of diabetes, increased chance of cancer, decreased cognitive functions even shallower breathing ... is having more hair worth the risk to your health in the future?
okay, new ovt unlocked
Citation needed
google it
so is there any other ways i am 17 yr old and i am suffering from dht what should i do to regrow 😢?
Cap
If i continue eating saw palmeto when i stop means it will effect danger hairloss ???????????
Pumpkin seed oil could be assessed too
In my opinion the scalp massages reduce and stop hair loss just as well as propecia.
@@mynutripartner I took Finasteride for 2 years but still experienced shedding and hair miniaturization. My hair looked thinner and my hairline receded even more. I decided to drop Finasteride and began doing scalp massages and was shocked by the outcome. My scalp felt amazing, I have stopped shedding and almost 3 months in I can see new hairs where my hairline use to be. So for me scalp massages reduced and stoped hair loss better than propecia.
@@mynutripartner I went to several dermatologists and all diagnosed me with mpb. However, the possibility that they were all wrong exists. Finasteride does work, however it does not work for everyone, no medication does. People who suffer from mpb should give it a chance since it’s safe and effective but in my case it did nothing. I had clear signs for mpb such as family history, receding hairline and diffuse thinning in the crown. Blood tests also came back normal.
@@mynutripartner you’re right that sticking with one is best and it’s what I’m currently doing. The first dermatologist I went to was in and out of the office in a matter of minutes, taking a quick look at my scalp, diagnosing me with mpb then told me to buy his hair loss shampoo and conditioner. The second dermatologist I seen was much more in depth and professional conducting proper tests then gave me the final diagnosis. They were also the one to first prescribe me Finasteride. The third dermatologist I seen wasn’t for my hair but for another issue I had in regards to my skin and while I was there I asked them to take a look at my scalp and hair loss and they gave me the same mpb diagnosis. Finally I moved out of town and had to find myself another dermatologist and that is the one I’m currently seeing.
Red Clover is an excellent DHT blocker too. People seem to forget that one. Then there is licorice, spearmint, nettle, aloe vera, etc.
Are there any studies on it?
Proof? Goes silent 😂
Hello, I have side effects after finasteride, I used it for about half a year, I stopped taking the drug 3 years ago, I have further effects such as weak erection, failure to maintain an erection, scrotum not holding the volume (dangling testicles), high testicular temperature, what medications can help me? How can you increase the enzyme 5 alpha reductase?
In my case, I tried saw palmetto. After about two weeks, I ended up with nose bleeds. I've since tried it a few more times at very low doses, and in all cases, the nose bleeds came back. So that one is out, unfortunately.
I tried saw palmetto for two months now man but I didn’t see any difference in hair density. and ended up with diherrea
Nizoral isn't going to do much. However, it helps a little. Dutasteride combined with minoxidil, micro-needling, zinc, eating pumpkin seeds (loaded with minerals and vitamins), are the way to go.
What are the side effects of Dutasteride like?
How do you know how much pumpkin seeds is enough😂?
What is it in pumpkin seeds that make them good for preventing hair loss?