L Tyrosine
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- čas přidán 28. 07. 2024
- In this video you'll discover the nootropic benefits of L-Tyrosine. Including why we use L-Tyrosine as a nootropic, how it's used to support ADD or ADHD with or without stimulant meds, the difference between L-Tyrosine and N-Acetyl L-Tyrosine, recommended dosage, side effects and clinical research.
L-Tyrosine is the master precursor required to form all catecholamine neurotransmitters including dopamine, norepinephrine, and epinephrine (adrenaline).
Sleep deprivation and extreme stressors like heat and cold can deplete catecholamine levels. L-Tyrosine restores them to preserve optimal cognition.
L-Tyrosine can be an effective treatment for ADHD symptoms. It works in synergy with ADHD meds by boosting extracellular levels of dopamine. Helping these drugs be more effective. And helping to prevent side effects like crashes when the drug wears off.
L-Tyrosine also contributes to the production of thyroid hormones T4 and T3.
Many neurohackers report a lift in mood, better focus, concentration, increased energy, and an overall sense of well-being.
L-Tyrosine can help readjust your motivation levels. It can help lower anxiety levels, especially social anxiety.
This in-depth L-Tyrosine review covers:
00:00 L-Tyrosine intro
00:27 L-Tyrosine as a nootropic
02:01 L-Tyrosine vs N-Acetyl L-Tyrosine (NALT): What’s the Difference?
04:10 How does L-Tyrosine work in the brain?
07:24 L-Tyrosine benefits
08:40 How does L-Tyrosine feel?
10:04 L-Tyrosine clinical studies
14:42 L-Tyrosine recommended dosage
16:09 L-Tyrosine side effects
17:38 Where to buy L-Tyrosine
For more on L-Tyrosine including a full transcript of this video and links to clinical studies, go to: nootropicsexpert.com/tyrosine/
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* The statements made in this video have not been evaluated by the Food and Drug Administration. The products and supplements referred to anywhere on Nootropics Expert channel are not intended to diagnose, treat, cure or prevent any disease. Please check with your doctor before trying any supplement mentioned in this video for your own safety. - Jak na to + styl
I supplement with l Tyrosine and i find myself more relaxed and less irritable specially if i take it before work and i handle escalation calls for 8 hours.
I take 500mg L-Tyrosine at noon, but I quit adderal and seroquel cold turkey in 2017 (and haven't had any tachicardia and tremors, or suicidal thoughts again) I'm going to order your book, since one copy of APOE4 is enough to make me fight for my brain health.
I just want to mention about this video, I noticed you're more upbit and at a faster pace than previous videos. Whatever you did it's more pleasant to listen to you when you don't sound tired. Many blessings to you, I appreciate your wonderful work❤🙏🏻
Elena, I am just getting better at it. Practice makes perfect as my Mom used to say.
I take L-Tyrosine, L-Histidine, and L-Theanine. Sometimes I go easy on the two 'Ts' sometimes i go heavy. If I don't have my acids available I go for 4 eggs, and am satisfied.
Whatever works for you keep on doing it!
Mr David you are the best.
Love your clear videos!
Thank you Alexander!
As always tnx very very much Doc David
Thank you!
Thank you David Tomen 🙌. Great info. Simply amazing. Super organized. And love your full transcripts to each video. It's great to listen and read along as you talk 👍
Thanks David
thank you always David!
My pleasure!
Excellent. Thank you 🙏
Glad it was helpful! Thanks Frank
I cant wait to stack some tyrosine with that new maca extract nootropics depot has and shoden ashwagandha.
Thank you for all the information you present to us. It truly is a weath of information and I, for one, am grateful for all you do to not only explain; but help people be the best of themselves.
Thanks Douglas. Much appreciated.
Hello from Australia mate!
I have been watching your vids off and on for years, and I have to add another comment as everyone else, that you are amazing and have given out such amazing source of knowledge. Thank you for that.
If I have missed it please excuse me, but would you ever do a video explaining some of your reasons to getting into this and how your ADD affected you in the past compare to now etc. I know you do talk about it, but I think because such a beautiful person that you are a sole video on the back bone of your story could also help alot of people understand more!
I lived in Japan for a few years from 16 and beloved I had adapted in a way, but since entering my late 20s and early 30s I have found my distraction levels go through the chart.
The reason I say this is also because I took nootropics in university but since learning from your videos and knowing you had add, it has made me look at my stack a bit differently!
Thanks for your hard work mate, keep it up!
Thank you BB. I do talk about my story on many of the Podcasts I've been on. And I have linked to many of those podcasts on the Podcasts tab for this channel.
Thanks again.
Great info thankyou
Thank you Stu!
Great info.
Thanks!
thanks ,this is mij favorite amino supplement ( i have ADD )
Thanks
Welcome
Thanks ❤️
You're welcome 😊
L-Tyrosine literally changed my life …I highly recommend it to anyone ❤.
unless you are taking antidepressants consult your physician.
Thankyou!!!!!!!!!!
I was super focused and motivated when I took for 3 weeks but after it made me awake at night
Use L-Tryptophan about 60 minutes before bed to increase serotonin. That should help balance dopamine and serotonin.
Hello, thank You so much for makin such informative videos, may I ask, reading the experiences of others and reading about side effects, could it be deducted from that, that if you have these side effects you might be having too much dopamine to start with and have no need for l-tyrosine, but on the other hand if you see that there are no side effects whatsoever it might be that you actually really need it?
Took my first dose and started with 1000mg right away but I experienced nothing bodily. Second day I split into 2 500g doses, feeling since yesterday a bit more awake and thinking clearly, also since I use it to learn I noticed more interest in subject and less fear from exam and generaly less anxiety.
It's possible. But sometimes it takes a few days of using a supplement before you can decided if it's right for you.
After 3 weeks of tyrosine major headache and nausea had to stop and supplement with 5htp
If all you were doing was increasing dopamine you were likely suppressing serotonin levels. Which is not good.
Using 5-HTP will restore serotonin. But if all you do is increase serotonin you will depress dopamine. Serotonin and dopamine must be in balance.
i only tried it once and it created a noticeable state of mental focus, almost a bit scary. but i can't remember if it gave me a headache but there's a reason I didn't try it again. it's been years but I'll try it again. but on the other hand, the first few times I tried Rhodiola Rosea it also gave me a strong effect in the beginning, but I don't seem to get any more benefits from it, so who knows if L-Tryosine will also lead to a plateau of perceived benefits.
L-Tyrosine has a half life of 2.5 - 3 hours so the benefits will only last total about 5 hours.
David, i have tyrosine in capsule form. Is it the capsule that contains magnesium stearat and silicon dioxide or is it the powder? If its the capsule i can just open it up and blend it with water right?
Magnesium stearate and silicon dioxide are mixed into the Tyrosine that is in that capsule. If you open the capsule and blend it with water you are sill getting those toxic ingredients.
Does anyone know if the naturally occurring L-tyrosine on the outside of unpasteurized sharp cheese is made disfunctional by melting it in the microwave, or cooking it in to a sauce.
Randall, good question. I think pretty much everything is dysfunctional after running it through a microwave.🙂
If you have withdrawals from these supplements, how long do they last? What are they from? Dopamine crash? How long does it take for the body to build up a tolerance? I’m concerned that there is a quasi addictive scenario here, even though I’ve really only gone through a single bottle so far and haven’t yet had any ill effects. I’m researching more about this supplement now that I’m looking to refill.
Jeffrey, if you follow dosage recommendations you should not have a problem. The standard adult dose for L-Tyrosine for example is 500 mg twice per day. It has a short half life so the Tyrosine you take at 8 AM is literally gone from your system by noon. There is nothing left unless you take it again.
I have never in all the years I've been doing this heard someone going through withdrawal from using 500 mg L-Tyrosine. For a very few they may need half that dose. But for most 'ordinary' folk 500 mg works.
Have you done a video on Inositol?
I have. Use the search function on this channel and search for Inositol and it should come up.
is it okay to stack l-tyrosine with dha, bacopa monnieri and creatine?
Yes it is OK
Hello sir, i have been taking antidepressants and anti psychotic medicine. Memory is not good. Please let me know any safer suppliments for memory improvement for long term and safe use. Thanks DAVID
See my video on learning and memory here for ideas to try: pulse.ly/plaolsx4ck. BUT make sure whatever you choose to try is not contraindicated with any of the meds you are using. Please, please check this with your doctor.
Question, why take L-tyrosine as a supplement if you eat enough protein sources with it? Just for the days you don't eat enough perhaps?
Good question. But are you getting enough L-Tyrosine or Phenylalanine from food? I know for sure that I do not.
is L-tyrosine effective immediately on the first day? or does it take a few days/weeks to notice a difference? I have chronic fatigue syndrome and adhd. I just received my bottle of L-tyrosine and i took my first dose about an hour ago. how long will it take for me to notice it working? I've been told different things... that it works immediately, and I've also been told it takes 2-3 weeks.
Angie, L-Tyrosine will make dopamine within 30 - 45 minutes after taking the supplement. As long as you have adequate levels of Vitamin B6, B9 & B12 because they are required cofactors in the synthesis of dopamine.
I've tried taking pure l-tyrosine at normal doses a handful of times. But each time I tried it, I immediately became noticeably irritable, almost manic. Went into a negative depressive state. What could be the reasoning behind this?
James, sounds like you already have adequate dopamine and norepinephrine in your brain. Those symptoms usually mean excess dopamine and norepinephrine.
I suffer from PMDD. I do not want to take any SSRI medications. I came across an article about using L tryptophan to increase serotonin. Would I need to take L tyrosine as well ? I’m afraid of dopamine suppression while using L tryptophan. Also, is L Tryptophan better than 5 HTP? Does L tryptophan and L tyrosine interact with evening primrose oil or any vitamins like K2 D3 and multivitamins and minerals?
Chynna, L-Tryptophan is far safer to use than 5-HTP because it is easier to figure out the right dose and you can use it long-term.
You must keep dopamine and serotonin in balance. But that balance depends on how much you increase serotonin.
Once you find that L-Tryptophan is no longer working for you that is how you'll know you need to start using L-Tyrosine to increase dopamine.
I have generalized anxiety (stopped gradually Paxil 50mg, been on it for 20 years and tried every possible antidepressant plus all the combination over the past 20 years and nothing works. I also stopped synthroid. I take kelp and apparently L-thyrosine is also good. I'm hypo not hyperthyroidism ) But I also have depression and chronic fatigue (I think it's adrenal fatigue, doctors do not look for that) since 2018. I cannot function or work. I started 5-HTP 2 days ago plus many supplements to support adrenals including a fulvic humic detox a month ago. I ordered L-thyrosine to add to my 5-HTP but I'm so afraid to take it. I don't know what to do. I'm constantly anxious, with adrenaline in my body, every day for 12 to 15 hours. I also have panic attacks sometimes. I also have about 20 migraines a month. It's been 30 years. Only imitrex medication works.
Don't know what to do. Don't know if it will worsen my anxiety. It's already up the roof.
Anybody can help me? Thank you.
Jana, you need L-Tyrosine and iodine along with selenium, magnesium and Vitamin C to make thyroid hormone.
The best thing I've found for adrenal fatigue are these 3-times per day: geni.us/Xzo6 (Amazon).
I also highly recommend that you spend a few hours reading this website and get your thyroid back under control: stopthethyroidmadness.com/
I got anxiety by taking 500 mg today first I felt calm but at the same time stressend and high blood pressure got spasm from it and anxiety in my heart palpitations. I dont want to scare u but dont take that high dose tis very Good in dopamin I felt so happy today really happy !! But restless also and stressed same time as relaxed.. I Will just keep taking l theanin thats for anxiety, 🙏 so if u already have adrenaline dont take this, try L theanin instead its better for relaxing. Tyrosine is not relaxing, is more like adrenaline rush same like coffein it Will higher blood pressure in some People. I got very alert focus and high energy after a while but like a stressful energy not Nice for People who are sensitive , other wise I loved it. But its nice half cup coffe with theanin, but if u are this sensitive maybe u should not even drink coffein I dont know in what level you are sensitive too
Then ALCAR is likely the wrong supplement for you. It affects how thyroid hormone works in your system so you may have thyroid issues.
@@NootropicsExpert what is ALCAR? I Know I have a very high metabolism maybe have to do something with that is that thyroid linked? How do one fix that? Im loosing weight very fast.. maybe I have a High thyroid then? Doctor what nootropic can u suggest for us with that problem that want to have same dopamin effect as L tyrosine ? I take theanin that one is Good, but doesnt higher dopamin as much as tyrosine ?
ALCAR is just L-Carnitine with an acetyl group added that helps carnitine cross the blood-brain barrier.
If you are experiencing those symptoms I highly recommend getting a full thyroid panel done. AND learn how to read your own labs. Because most doctors do not know how to.
This site was my bible when I was first diagnosed hypothyroid. I suggest you spend some time reading and learning: pulse.ly/lozux9ejgg
L phenylalanine vs L tyrosine? Which one is more efficient and affective?
Mark, Phenylalanine is 3 steps away from creating dopamine and Tyrosine is 2 steps away from creating dopamine. And Tyrosine has a longer half-life so its effects will last longer.
I just got some David...topping up MLP how much was my question and you address it, it is higher than my supplement company...but still lower than a few sports science coaches I've read...and think MLP with this is smart.is too much as far as the tyrosine.
I know Tyrosine is water soluble whereas Phenylalanine is not... should I weigh it up, and can I put it in water to sip on or just work out the dose?
My music if flying and i have begun programming.
If I can have it in water for example. can I sip on it or does it degenerate. over time?.
Also does Sun degrade it?
I'm thinking similar dosage to you but sip on it during intense music study and programming.
Thinking 1.2 grams a day in three 400mg doses and a sip during study.
Last thig coffee before or after how long or simply avoid it for a while?
Harris, I suggest just working out the dose. I use more Tyrosine than you but it is what my brain demands. Keep in mind that Tyrosine has a half-life of 2.5 - 3 hours. So whatever you take at 8 am is gone by noon. Sipping it during the day will not likely work very well.
The caffeine in coffee forces your brain to release more dopamine. So supplemental Tyrosine will support caffeine use.
@@NootropicsExpert thanks
Hello. Is the consumption of Tyrosine bad for dopamine receptors ? ( dopamine receptors downregulation ) . Thank you.
Those dopamine receptors need dopamine. And the only way to get the dopamine you need is either Phenylalanine or Tyrosine from food. Or a supplement.
L-Tyrosine is a natural way to produce dopamine and will NOT down regulate anything including dopamine receptors.
@@NootropicsExpert Thank you. Most appreciated.
You are welcome!
why when i try to take it/ a pill, it seem to make me weak and sluggish? I got Hashimotos and use natural desiccated thyroid.
Because L-Tyrosine is involved in thyroid hormone production. When you use Tyrosine with natural desiccated thyroid it sounds like you are producing too much thyroid hormone which is upsetting the balance you have achieved with your meds.
@@NootropicsExpert Thank you! I thought the same, theres something that making too much Thyroid hormones', on top of my hormone meds... I dont take them at same time, a few hours apart...I wonder if its same for other Hashimotos patients, I should google it. So, that means Tyrosine is a nono for me, or its it possible to still use it up somehow? For instance, can I put it in my facial potions or whatever?
You'll not get enough through your skin to make any difference.
But it's different in everyone. I'm very hypothyroid and use high doses (compared to most) of natural desiccated thyroid. And use L-Tyrosine without a problem.
But I've figured out how to balance them I suppose.
Any Supplements to heal the brain after damaging it by taking benzos and antidepressants ?
Raj, avoid anything that directly increases GABA or serotonin because those receptors are desensitized. And you will just aggravate them.
Best thing to do to rebuild your brain is boost Nerve Growth Factor and BDNF (czcams.com/video/htMpJQSpcC8/video.html). Add Lion's Mane extract to that list. And get a high quality, bioactive Multi, 1,000 mg DHA per day, and 400 mg magnesium before bed. That's a good start.
And consider scheduling a consultation with me.
Instead of taking tryptophan for long term use side effects of decreased serotonin can one take ltheanine instead
Darlene, it is literally impossible for L-Tryptophan supplementation to decrease serotonin. It is a precursor to the synthesis of serotonin. When you stop using Tryptophan you have to hope that your gut can get enough from food alone. Which for many people is not possible. For a variety or reasons.
Is there a problem taking l-tyrosine with nicotein gum ?
L-Tyrosine supports nicotine use.
I was having a lot of anxiety and insomnia i start taking 5 htp and i feel great then after 3month i start feeling anxiety and having poor sleep and waking alot at 4 am and my heartbeat fast
Maybe because the dopamine levels was low so start to take tyrosine without 5 htp and i start to feel better but also after 3 month now i cant sleep my heartbeat fast and i wake suddenly at4 am
I thought maybe i should return to 5 htp but also it didnt work my heartbeat fast and couldn’t sleep
Plz help me
Shaheen, dopamine and serotonin must be in balance. Too much dopamine suppresses serotonin. And too much serotonin suppresses dopamine.
I have found a good balance using L-Tyrosine 500 mg 2 or 3-times per day along with 500 mg L-Tryptophan before bed. I've been using that combo for years and never had a problem with dysfunctional neurotransmitters.
Your thoughts? on the Bang energy drinks loaded with EAA.
The biggest problem is the "amount" of each amino acid is not detailed. So you don't know how of each your are getting.
You say it buffers amphetamines, so is it good to take with vyvanse? as you say its good with ritalin and adderall?
Ben, I think you need to listen to this video again and closely this time. 🙂
L-Tyrosine helps produce the dopamine and norepinephrine. Using amphetamines, Vyvanse, Adderall, and Ritalin works on those pathways in your brain.
If you do not have enough dopamine or norepinephrine in your brain those stimulants will not provide their full benefit. But supplementing with L-Tyrosine provides that dopamine and norepinephrine.
I am a lean man
I took tryptophan and it suppress appetite
So I am looking for other ways to increase my serotonin, can anyone help?
Why do you want to further increase serotonin? Sounds like you may be able to balance things out by supplementing with Tyrosine. That should get serotonin back into balance with dopamine.
If L Tyrosine increases the production of melanin, what consequences,( if any) would it have on an individual with a genetic predisposition to skin cancer/ melanoma?
It doesn't have any influence on skin cancer or melanoma. If you did not have melanin your skin would be white as a ghost.
Another interesting one is butyrate, not sure if you have a video on this
Butyrate is a short-chain fatty acid that is involved is producing ATP in mitochondria for energy. I do not think there is enough research specifically on how it contributes to human brain health and cognition. If there is enough I will do a review on it.
Butyrate, good stuff, It's a substantial precursor to fixing the intestinal microbiome. A nesessary component to fixing intestinal permability (leaky gut) and achieve bioavailabiliy. Because, (leaky gut - leaky brain). No one needs to have all those lipopolysaccharids and free radicals floating around their bloodstream or getting through the tight junctions in the blood brain barrier, causing neuro-inflammation, or anywhere else for that matter. So, to fix this problem, gotta have a adequate supply of (Butyrate) in the large intestine. (Butyrate), by it's self, as a nootropic, I don't believe so, but it is complementary. I couldn't figure out how to spell (senergenic) for the last word in my post so I guess it's complementary.
@@NootropicsExpert much appreciated. the connection brain and gut seems to be essential. and the absortion of it seems to be the issue but apparentl the micro(sth) capsules do the trick. looking into probiotics as well (prebiotics) . would be interesting to know more about the gut and the brain. I would like to give you my congrats as your channel is fantastic and i really appreciate all the info you share, helped change mylife, God bless you
czcams.com/video/r38OSqyPvyM/video.html
And prebiotics trump probiotics in my opinion. Because with probiotics there is no way to tell which good bacteria need support. But Prebiotics are just food for your microbiome. You let the built in intelligence of your gut figure out which beneficial bacteria to increase. Helps suppress the bad bacteria too.
Hi David,
Do you think a messed up brain chemistry can be balanced? VMA is low and HVA/ VMA is high.
I am treating VMA with SAMe.
I also bought BDNF
You can't "buy" BDNF but you can increase BDNF with nootropic supplements. See my video here on how to increase BDNF: czcams.com/video/htMpJQSpcC8/video.html
Yes, you can balance brain chemistry. You do it using precursors for each one until you figure out which one is low. They keep on supplementing with that precursor. See my video on anxiety which explains on how to experiment with each one: czcams.com/video/Qu4zVAmscK0/video.html
So are you in agreement to use riddlin?
Lucy, If you mean "Ritalin" I am Adult ADD and have been using Ritalin every day for the last 14 years.
L-tyrosine gave me irregular heart beats. Be carefull
👍 👍 👍
✌️
Have you considered making a video on Rubidium Chloride? Apparently, it has proved to be very effective against certain kinds of depression.
I will definitely get some as soon as I can afford it. I believe my depression is dopamine-related, and I suspect that's the case for most people with depression. I wasn't at all surprised to hear that the serotonin-deficiency model has come into question because it doesn't make sense anyway, and I've heard the same thing years ago. I only wonder why it's made the news now - I imagine they're revving up to market something else that's equally ineffective.
I know there are alternatives out there such as welbutrin, but I'm in the UK where the GPs seen to be particularly unimaginative, so I've no chance of getting anything which might actually be effective on prescription.
Anyway, sorry for the whine - I know the grass is always greener. It just rubs it in when people casually talk about asking your doctor about these exotic things - it's the only thing I dislike about videos to do with nootropics, longevity etc 😄
Eman, Rubidium chloride is not easily available as a supplement.
But if you think your depression is dopamine related why not try L-Tyrosine first to increase dopamine? And see if it works?
I gave l thyrosine to my son and he started acting weird abd angry.
It turned out he has excess dopamine because the enzyme that convert dopamine to norepinephrine is not working properly. Any idea how to fix this?
First, do NOT give him L-Tyrosine or any supplement that boosts dopamine. There is no natural method of restoring that enzyme that I'm aware of.
Yohimbine, cistanche, horny goat weed, tongkat ali. Hope to see you switching to research chemicals like bromantane and 9mbc, we need a trusted source.
If any of those supplement support human brain health and cognition I'll review them.
Polygala-tenuifolia, Cistanche, Yuan Zhi, Japanese knotweed, trans e viniferin, bilberries, etc. (Their are quite a few)
czcams.com/video/BnkMna7hBC0/video.html and czcams.com/video/Hrbs0BNbFh4/video.html
Basically L-Tyrosine makes you like Albeit Einstein
Pat, look what did to me. 😁
Thanks
Tis my pleasure Ayape.