Coagulation Tests - PT, aPTT, TT, Fibrinogen, Mixing Studies
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- čas přidán 26. 06. 2020
- Coagulation Tests (PT, aPTT, TT, Fibrinogen, Mixing Studies,..etc)
Prothrombin Time (PT/INT),Activated Partial Thromboplastin Time (aPTT),Thrombin Time (TT),diluted Russell Viper Venom Test (dRVVT).
The coagulation factors are divided into 3 coagulation groups | Fibrinogen group, Prothrombin group, and Contact Group..
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Platelet count is one of the lab tests used by a doctor or a hematologist to assess whether your platelet number is normal, low (thrombocytopenia) or high (thrombocytosis).
Bleeding 🩸 time (BT) is another test for platelet function.
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صوتك كريهه ترا
This is good knowledge however the presenter is tooo fast, he is actually rushing through the staff. Please reduce the speed
Hey man loved your video, just another way I remember aPTT and PT is that you Play Table Tennis inside (intrinsic) and you Play Tennis outside (external).
Great
wow that's actually really good
I like it!
@@MedicosisPerfectionalis OPS , Great that you like it after 8 month 🤣🤌
Haha 🤣
Every lecturer should take note! This is how they should be teaching! Detailed, fun yet no nonsense. A very interesting and informative 19-minute video that is way better than a 2-hour university lecture! :)
Wow 🤩
Thank you so much, Rachel!
Your kind words mean a lot to me!
I love this! Finally someone who speaks quick enough to keep me interested and not mentally wandering off to other topics. Great level of detail as well! Thank you very much for this!
m a final year student in India this so basic part was not even clear to me the way you taught it is magical
Thank you so much 😊
Good luck 🍀
I love the way you interject mirth in almost all "strategic" points, and appropriate quotes each time. You definitely take off a lot of psychological and emotional load from the way you present this convoluting processes. God bless to you, and keep this up.
God bless you too, Catherine!
I appreciate you so much!
It helps tremendously with hooking the memory up at the right place. It is a virtuous-work.
About to start my first job in the lab. Your videos have been the best and the most fun to watch. Never thought that learning could be so fun and easy. Take this sub, you dirty professor!
Thank you ☺️
love the quotes that in middle of video , it gives impression of your knowledge spectrum ماشاءالله
Thank you so much 😊
No words to express how much I love your videos‼ so easy to understand. Thank you.
When I wake up in the morning,I just watch your videos! What a simple and clear explanation...!!!
Thank you so much 😊
Thank you so much. When I start working I’m totally donating to your patreon. You deserve it
Wow 🤩
Thank you so much 😊
You make problem-based learning sessions so much easier for me and my group; our proctor/professor goes so quickly through the tests that we never get a good explanation for what they actually mean. Thank you for being my online professor!
My pleasure 😇
Awesome note explanation and really appreciate all those references and jokes. Found your video while searching for DIC in Covid-19 patients.
Keep up the great work.
Thank you 🙏
i love this video i finally understand the difference plus u solved the quiz in beginning in a way that makes it easier to remember
the funniest medical youtuber I've ever seen haha, thank you so much
GOD!!! This saved my life. THANKS a million!!
My pleasure 😇
Remember Exodus 20:7, God bless!
This made my concepts crystal clear. Thanks infinity.🤗
You’re very welcome 😊
Great video! Just a note, the Pro time usually is not prolonged with therapeutic levels of heparin because the reagent contains a heparin neutralizing agent.
Another side note is when you were describing drvvt testing, you mentioned patient's serum, but we still use plasma! (The blue top)
احسك عربي مدري ليه؟
لو كنت عربي حقيقةً انا فخورررة ان عندنا واحد مثلك♥️♥️♥️♥️
you are a Gem!
Thank you so so so much!
Feeling confidence hearing your voice, its like- I can do it when you start teaching!
At my pace. Thank you. Get bored listening to others who are slow in delivering lesson.
Thank you so much 😊
📝 Download my handwritten notes: www.medicosisperfectionalis.com/
Just I typed Blood coagulation tests..
U tube take me in the magical world of medicine..😍❤️📖👨🏻⚕️👩🏻⚕️
Love from India .🙏🏻😷
randomly found your videos and god I needed this 4 days before clinical chemistry exam xD god bless you
Thank you so much 😊
God bless you too!
@@MedicosisPerfectionalis thank you! also update: I passed :D
Love this video, thanks for saving me from tomorrow's exam!
My pleasure 😇
Good luck 🍀 to you!
Highly organized medical ideas. Thank you great Doctor . I like you sentence " where medicine make perfect sense " .
Thank you for your continuous encouragement!
@@MedicosisPerfectionalis have a blessed Thanksgiving full of health, joy and peace .to you and to your family.
Best lecture the which I enjoyed and learned at the same time your teaching methadology is superb bro ❤️ wanna see millions of subscribers for this channel
Thank you so much 😊
Dear M.P. it was awesome, like always. I had one last thought at the end: "Rolls-Royce?... it might feel like that from behind the wheel (for you) but surely it feels a Lambo Diablo from the passenger's seat." 😊 Special thanks for the warfarin info - on the platelets.
You’re always welcome, Anna!
@@MedicosisPerfectionalis 😊
I love you so much! When I graduate and start working I am going to donate a large sum of money.
Thank you so much, dear :)
I really appreciate it!
love all of your videos! you are a life saver!
Thank you 😊
Great video! I have a question. If you are kind enough to answer i would really apreaciate it! Why it is easier to track heparin via
PTT and warfarin via PTT?
Excellent! No words to say thank you !!!
My pleasure 😇
Best informative and funniest 19 mins of my life during stressful exam times 😅😂😂
Wow 🤩
Thank you 🙏
Good luck with your exams!
You are a legend 🤩 I enjoyed and learned at the same time 😊
Thank you for these beautiful videos they really help. I have a question, what is the 'partial thromboplastin" why is the test that measures the intrinsic pathway called activated partial thromboplastin test while thromboplastin is the key factor in the intrinsic pathway?!!
i wish i knew your channel while i was studying
now am an intern and am getting a huge benefit from your channel
Thank you 🙏
I love how simple you make it for all of us!
Thank you so much for your continuous encouragement!
شكراً لك♥️ شرح ممتاز ♥️
Thanks, Excellent explanation
As a fellow Egyptian, I am proud of you and your work ❤
Thank you!
Thank you. You just made it so simple and easy to understand.
My pleasure 😇
Much awaited video..Thanks medicosis
My pleasure 😇
Haha I love the "Lenin, may he rest in peace" part XD
Haha 😂
AT 13:20, Warfarin will not increase thrombin time since it works by inhibiting the synthesis of vitamin K that will affect the synthesis of prothrombin, however in TT test, thrombin is directly added to the plasma
love the way you speak in your videos
Thank you ☺️
your explanations and recaps >>>>>>>
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I ask myself, why I go to college and waste my time for boring and hard lecture while medicosis make all medicine easy
I am grateful to you
Biggest thanks for this channel
I am honored!
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Would you please help me by sharing?
@@MedicosisPerfectionalis yes I was do it before asking
I’m sharing the lecture with my friend
As usual amaaaazing 🌸🌸🌸🌸
Thank you
Great content as always man! Your Egyptian "r" showed up a bit in there HAHA!
If I ever come to America, or any other English speaking country for that matter, I plan on retaining my rolled "r", because I find it very difficult to pronounce the American "r" especially the "r"s coming in succession.. Any advice on rrretaining my accent? :)
Haha 😂
Why do we get INR from PT and not from PTT?
Please answer 🙁
Deficiency of Vit K why not affect prolong pTT as it share in synthesis of coagultion factor in intrinsic pathway?
Explained very well💯👍🏼 Thank you😃
Did you create all of the notes in this video? They are AWESOME, what program did you use?
Yes…I do them with my own handwriting!
Please send me an email and I will gladly tell you about all the apps that I use.
medicosisperfectionalis@gmail.com
Indeed my favourite medical channel.
Thank you 🙏
@@MedicosisPerfectionalis no man thank you, you put my teachers to shame, my only regret is that I wish I knew this information could be found on youtube years ago
thanks very much for the video ! BUT I don't understand why Warfarine (Antagonist VK) prolong TT ? because Thrombin is the reagent that we add so we don't need factor 2 (who need VK) for the reaction ...thanks
Its very informative and fun 💗
Keep it up and stay blessed 🧡
Thank u for the great video!! Im a lab student preparing for SLLE and u helped me a lot! May I ask In which video did u talked abt the methods for testing coagulation factors assay? (Clot-based assay….)
Watch the playlist “Bleeding and Coagulation” especially the ones around hemophilia, factor XII, and factor XIII.
Excellent teacher, love your lect.
Thank you 😊
the Rolls-Royce of medical education baby
:)
you are so funny and informative! enjoyed this video. thanks!
My pleasure 😇
i wish u were my med school professor -- thank you!!
Thank you so much 😊
Did u just quote Nietzche in a pathology video? 😂 I like it
Haha 😂
I know I’m a nerd 🤓
I can'nt thank you
Your explanation it's amaaazing.
Thank you 🙏
hi i had some tests done in november and my fibrinogen levels were really low but the doctors are not saying anything about it. my rbc platelet count dropped by almost 100 also. it was normal in bloodwork i had done just a cpl weeks before in two separate labs. what cld that possibly mean. im suddenly experiencing joint, muscle and internal inflammation and now losing weight and even though i’m still eating. one doc is saying it looks like RA bcuz i started experiencing some swelling in my right thumb knuckle but only in my right hand
Hello what would you say the PROTHROMBIN TIME should be for INR 2.1?
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You are such a genius! your help is priceless!
loved the way u made it so funny...i ll remember everything for sure
Loved your video, cheers!
I have a question. How does dRVVT detect APS if both are coagulants? APS causes dimerisation of beta2GP1 and causes activation of Factor XI. dRVV activates factor X. Both cause coagulation eventually. How does adding dRVV help in detection of beta2GP1 in a APS patient's plasma, then?
hey medicos, I really appreciate your videos very great work and I totally watch them helped me a lot thanks for that but I have once concern
during 12:15 warfarin should prolong PT and heparin should prolong PTT unlike what you wrote, this information is from Amboss if am wrong please correct me
thank you and AMAZING VIDEOS KEEP IT UP
Heparin prolongs both PT and PTT.
Warfarin prolongs both PT and PTT.
However, in the lab, clinically speaking, it’s easier to track heparin via PTT and to follow up with warfarin via PT.
God level. Thankyou so much!!!!❤️❤️❤️❤️❤️❤️❤️❤️
My pleasure 😇
أنت رهيب جدا جدا جدا 🥇
Thank you very much !
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Your vidios are just 🔥🔥,thanks man ,u life saviour
Thank you 😊
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Yup 👍
U r SUPER PERFECT doctorrrrrrrr💙💙💙💙💙💙💙💙💙
Really thankful!!!!
Thank you 🙏
My favorite medical channel
Thank you 🙏
Hi Medicosis in antiphopholipid syndrome I thought APTT is elevated in vitro, is PT also prolonged?
Both can be prolonged.
Remember the common pathway
I like it: "the Rolce Royce of medical education".
Thank you 😊
ومن السموم الناقاعات دواء! ... كبير وشاعر كمان .. تحياتنا لك
Thank you 🙏
Thank for your video..I have one question:dose deficiency of vitamin K ,prolonged aPTT and TT??
Yes, it can!
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I’m soooo happpy
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Thank you 🙏
Please make a video is Anty phospholipid syndrome Like this! You rule in hematology Master! 🤓😎
Thank you so much 🙏🏻
I am an Indian, I struggled to understand your pronounciation, what accent is that?
An alternative acronym to remember immunoglobulins could be GAMED
Yes!
Bravo ....love from Pakistan.....homeland to dr najeeb
nice lecture...good work
does anyone have an answer for why liver disease causes prolongation of PT and aPTT? I understand that it does, but can't find a reason why despite the links with prothrombin production and vitamin K
Because liver produce the factors which helps in coagulation process. So if liver is damaged then factor will be low in blood and clot won't happen thus PT and APTT will be prolonged. Simple!
This help me a lot, Thanks♥️
My pleasure 😇
شكرًا لوجودك في حياتي 🤍
Thank you so much 😊
Great video 👌
Keep it up !
Thank you so much 😊
اسطورة والله العظيم اسطورة ومصري بعد 🤯❤️❤️
Thank you so much 😊
Sir I would like to ask if you have uncorrected pt and aptt what should be your next step? is it mixing studies oe drvvt?
What do you mean by “uncorrected”?
4:45 saved hours of fishing through books , google , youtube ....... thank u 🌚😇♥️
My pleasure 😇
Hello! Can you tell me why does fibrinogen increase in inflammation Where I can find the explanation for this? Thank you!
It’s an acute phase reactant. The liver is working like crazy during inflammation.
is their any case that blood clots in time less than the normal range (in less than 2 minutes)?
invitro clotting
Are you talking about BT, PT, PTT or TT?
Great work! once single word made me writing this comment!
So, don't underestimate ur menmoincs please!
Thank you so much 😊
Why PT is prolonged when fibrin split product elevated and when the antiphospholipid antibody elevated?
In which disease?
Thanks for your lecture notes of
Of what?
It is Brilliant my friend ❤thx
My pleasure 😇