Hemophilia A - Bleeding - Most Comprehensive Explanation - Hematology, Bleeding, and Coagulation
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- čas přidán 11. 07. 2020
- Hemophilia A - Bleeding - Most Comprehensive Explanation - Hematology, Bleeding, and Coagulation.
Hemophilia is a genetic Coagulation Disorder characterized by abnormally excessive bleeding 🩸 even after a minor scratch. Hemophilia is divided into three subtypes: hemophilia A, hemophilia B, and hemophilia C. Hemophilia A and hemophilia B are X-linked recessive, whereas hemophilia C is autosomal recessive..
Coagulation Tests (PT, aPTT, TT, Fibrinogen, Mixing Studies,..etc).
The coagulation factors are divided into 3 coagulation groups | Fibrinogen group, Prothrombin group, and Contact Group..
Platelet count is one of the lab tests used by a doctor or a hematologist to assess whether your platelet number is normal, low (thrombocytopenia) or high (thrombocytosis).
Bleeding 🩸 time (BT) is another test for platelet function.
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😂😂😂 this is me reading to myself when I'm studying alone
Haha 😂
I like this method!
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@@MedicosisPerfectionalis kindred spirits 👌👌👌🔥🔥
😊😊😊😊😊😊😊😃
Me too! Trying to comprehend. This is me pictures and all!
HAVING HEMOPHILIA SUCKS ITS SO ANOYING and boring when I get hurt teachers run around like headless chickens
This is the first video of yours I’ve watched and I will ABSOLUTELY be sticking around for more, this is so funny and informative, I loved it!
Awesome 👏
Thank you 🙏
I’m in PA school, and you’re breaking this down in the only way my adhd cartoon brain will absorb it-super thanks to you big boy!!!
I am honored! Thank you so much for your generosity!
YOU ARE THE BEST! I absolutely love your videos! I have ADHD and you are the only channel that has my attention throughout Physician Assistant school! You are the best!!!!!! I can understand so much more from your videos as opposed to 2 hours of lecturing!
Thank you so much 😊
I am honored!
Exact same!!!!
Ok, there is just no way that a non-Arab could pronounce Al-Ansari's name so perfectly
:)
He is Egyptian
This is like, the best medicine channel ive ever seen! Thank you so much dude! Lots of love from Brazil
Glad you enjoy it!
🙌🏼🙌🏼🙌🏼🙌🏼 thank you soooo much! It’s much easier to learn with your videos!
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Medicosis Perfectionalis is another level.
Your are an international scholar dude.
If you visit my village in northern Somalia, only in that village, a half of the students are just yours.
Man, you are WELCOME to the world of your students.
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I appreciate you so much!
I love this so much. I laughed while learning. Well done :)
Thank you 😊
You are born to teach. Its sufficient for any student to follow your videos only. Tnx
Thank you so much 😊
Much love, this video is both helpful and entertaining!
Thank you!
I LOVE how you explain stuff, always the most informative and simple presentation
Greetings from Egypt 🇪🇬
Thank you!
I love your way of teaching lol! Thank you thank you!!!
My pleasure 😇
I didnt't expect that SMASH! when explaining what Emicizumab does. Gave me a little VES!
Haha 😂
you deserve more views and likes, im sure they are to come! :) thanks!
Thank you!
You are so funny! One of the main reasons why I love your videos
Thank you so much 😊
Wow u did amazing job please make more videos,i am happy that i found this channel 📚
Thank you so much 😊
really useful! thank u
Thank you so much 😊
You are my favorite mad genius. I silently laugh at certain patho and people probably think I’m leaning toward the mad side but hey whatever works. Thanks my friend
I like your style of teaching by giving great introduction 😁
Thank you 😊
Man I hate haematology, but Alhmdulilah you made it easy for me to understand, thank you 🌷🌷🌷
My pleasure 😇
Hemophilia A treatment is PDF VIII concentrate ? ( typo error VII)?
You should organize a fan meeting, I'm sure there will be many people who will want to thank you in person, including me, because you're just awesome. You can put all my professors in your back pocket and sit on top of them.😂
Thank you so much, Nermin!
I really appreciate you!
love your style of teaching❤❤ Thank you so much for this😊😊
You are so welcome!
Loved the way you roasted biology teachers.
You're an absolute legend!
Great review very informative thanx for sharing ⚘⚘
My pleasure 😇
You are the best ever❤❤❤
Thank you so much!
Thank u so much doc
My pleasure 😇
you have a good pronunciation of the arabic name, btw your videos have helped me a lot for past few months. Thanks!
My pleasure!
Thank you very much for your effort
God Bless you!!!!!!!!!!!!!!
God bless you too!
Thank you doctor
My pleasure 😇
'Kiss my calcaneus' always gets me.
Haha 🤣
The best videos!
Thank you so much, dear :)
🧡🙌🏼🙌🏼love ya.
Thank you so much ☺️
The story lines are interesting.
Thank you so much 😊
Hello !!! I have some questions about hemophilia A. What do you think? Which years old the hemophilia will be disappeared.
And what do you advise for youngers and adults to grow up brave without any pains and bevel arms or legs.
Thanks for answer...
Thanx alot dr
Dude i love u , i adore u ❤this mixing study my teacher explained it 5 times and i got nothing!!
Glad I could help!
absolutely looooove this lecture, soo soo creative. you pronounce Arabic sooo good, im half arabic & cant pronounce it like u, wow!!!!
Thank you 😊
I appreciate you!
@@MedicosisPerfectionalis oh I adore u 💖 💗 💓
😃☺️😊
By the way medicosis is egyption 🥰
I thought I’d never find my Dr.Cox, but here you are
Haha 😂
This is truly one of the most comprehensive explanation ever. Bravo Medicosis perfectionalis 👏👏👏
Thank you 😊
I think the answer for the question is because the patient has antibody against the Factor 8. Btw your explannation is amazing. Thank you for sharing your knowledge.
Is pencillin z contra indicated in this case?
Hi.. first thanks for the amazing videos... I have a comment about the treatment of hemophilia.. It is written concentrated fact 7 but you mentioned fac 8. I know fac7 concentrate is also a treatment but just wanted to say you wrote 7 if you meant 8 and if you meant both, please add 8 as well :) One general comment: you can draw a spine or a pelvic bone rather than a long bone for "bone marrow" references :) once again, thanks! love your videos
Thank you so much, Sara!
I meant factor 8, not 7
Sorry about that!
@@MedicosisPerfectionalis No worries but fact 7 concentrate is also a treatment in resistant forms, so you were technically right :)
Very nice thank you
My pleasure 😇
شكراً 🥰
🙏🙏🙏
Wonderful teaching style
Thank you!
Loved the way u explained the whole concept, as well as ur cross talks.! Thanks a ton❤️❤️❤️.!!!
My pleasure 😇
i really liked when y talked about the first doctors in history"al zahraoui ..
this is amazing XD
Thank you so much 😊
Thank you so much
Of course!
I appreciate it!
Thank you ♥️
My pleasure!
Now i knew where the name Maimonides medical center in Brooklyn came from . I was going to have my rotation in Maimonides before graduation.
Good luck 🍀
Why did I just had an instinct that medicosis is Egyptian guy! I'm not sure but that would definitely make me super proud
Yes, I am :)
@@MedicosisPerfectionalis wow! That totally explains the amazing sense of humor! 🤯❤❤
This channel is the story of how I fell in love with Patho hence Medicine too …..
Thank you so much 😊
انا فخور انك مصرى بجدددد
Thank you 😊
heyy 🖐️🖐️great doctor i ever seen 🙏 please you make mnemonic of clotting factor
That’s a good idea 💡
16:02 you write there f 7 but you say true :)
thanks for video i click when i see your notification.
greetings from Turkey!
What do you mean by f 7 ??
@@MedicosisPerfectionalis factor 7 writing on there
Oops 😬
why was i laughing during the whole video😂😂😂 i enjoyed it😍😍
I am so delighted!
You are the best 😂... lemme go shine during the ward round
I am honored!
Ur pronunciation of the Arabic names is just greattt 😂 love it
by any chance are you an arab? because the way you pronounced Abu al-qasim khalaf was WOAH.😌
I am!
on mixing studies, i think you should say that the aPTT remains prolonged (high) not low!!
Yes
Thank you very much ❤
and the answer still could be von willebrant disease (type 3 ) even if it is milder than hemophilia but the common is common
My guess on the question is that the girl's parents both have a defect on the genetic material. Father is very likely to be hemizigous and the mother homozigous resesive.
You got part of it!
Please see the answer in the next video!
Thank you so much 😊
It is an honor to hear you pronounce the name in Arabic
Thank you 😊
The first part of the video was just like i'm watching a comedy movie 🤣🤣❤
But sir i didn't really understand the idea of x-linked recessive, the carrier thing and the whole mechanism i always had problems understanding those heredity-related stuff :( would you please help me with it? Or if you have a video where you elaborated a lil bit more about heredity, please put me a link 💔 and thanks alot.
In treatment factor viii is used or vii? U r saying viii but in video it's vii showing
Oops 😬
Sorry 😐
hey Medicosis! @16:35, u have mentioned the treatment to be recombinant factor 8 while writing factor 7.... it's like warfarin hypocrisy( meant to be anticoagulant but worsening DVT in HIT-2) haha....( i understand u meant it to be 8... also factor 7 helps in hemophilia a)
😂
اخويا فخر مصر ❤❤❤
🙏
U r amazing 🙏
Thank you!
U r so good tq sir
My pleasure 😇
Hi ,thanks for the mesmerising explanation!
I have a qst , why are corticosteroids given to Haemophilic patients? Aren't they supposed to block arachidonic acid pathway by blocking phospholipase A and have antiaggregant effect on platelets therefore they worsen the hemorrhage and do not improve it !? But at the same time cortisol in high doses has a procoagulant effect! This is really confusing and contradictory 😭 can u answer that qst plz and thanks in advance
I’ve never heard of giving steroids to hemophilia patients!
@@MedicosisPerfectionalis hmmm ,no it's not to treat the pathology (Haemophilia)itself, it's used to treat hemarthrosis for example ,by inhibiting inflammation, the paradoxical thing here is that corticosteroides inhibit platelets aggregation isn't it? So corticosteroides in this case are like a honey mixed with poison lol how can we explain this, sir, in your opinion?
When you get faster .....
I cant breath 🤣
More Thanks from my galaxy 🥰
Thank you 😊
Wow, U r from Egypt ✨
XLD >> Hypophosphatemic rickets
Case scenario : it could be vwD tybe 3 i geuss
answer to your question is : the woman must be the carrier.Due to some causes may be the reason may be drug therapy the dominant gene gets inactivated then the recessive gene express itself and disease manifest clinically
Hmmm. she has inherited an inhibitor against factor V111. Don't know. BTW your graphics are amazing. But then I am an artist and not a scientist. Different side of the brain eh! Thank you for your dedication toward teaching of everyone who comes to your site.
You’re very welcome, dear :)
Thank you so much for your kind words.
Haha 😂, yeah, different side of the brain...You’re a scientist too :)
Regarding the question...I don’t think there’s a difference-genetically- between a deficiency and an Inhibitor...If it's X-linked recessive, then it’s X-linked recessive whether it’s a deficiency or an inhibitor.
Can you please try again?
@@MedicosisPerfectionalis I'll attempt it again. Her F V111c is low because she has type A, despite being female. Most people with type A are male.
@@hannahrosa5485 vWD I think.
Nice when you talk Abu al qasim like the native Arabic people ❤😂
Good , I like all vediow
Thank you 🙏
the mother was a carrier and the father a sufferer ,so she got two affected X chromosomes, one from father and one from mother
Excellent!
I loved your vidoes soo helpful in pediatrics study ❤
Are u Egyptian? The way you say abu el qasim khalaf *
Yes he mentioned it in a video
I think the baby girl’s father is hemophilic and her mom is the carrier . Or her coagulation factor VIII is inhibited by antobody
Ehy BT is normal??? If BT is normal.. then why small cut leads to a lot of bleeding. Please reply bow I have exam tomorrow.😅😭
Factor 10 is her baby😂😂😂
U make mi whole day
:)
Yooo how did you pronounce the Arabic name so good dude
You are funny still 🤣🤣🤣🙌🏽
Thank you so much 😊
I think CZcams needs to create a laughing emoji button just for you😂.
I never forget the things I learn here, thanks to your method of teaching
Thank you so much 😊
Hahaha woww you make it soooo lovely 🤩
Thank you 🙏
@@MedicosisPerfectionalis my pleasure
Now i NEED to know where are you from .. that was PERFECT ARABIC i would be very amazed if you were not arabic yourself
Egypt!
Heterozygous females who have randomly inactivated a higher percentage of X chromosomes with the normal gene may become symptomatic, as may homozygous females
4:22 Al Zahrawi!!!!!!
This is so much simpler than what I learn in nursing lecture 😂😂
Awesome 👏
omg this is so funny 😂
my man minute 16:30
in the treatment section it should be factor 8 instead of seven
Yes
🌺🌺🌺Nice 🌺🌺🌺
Thank you!
female have a hemophilia symptoms bcj one x is affected and one is missing sometimes it depends on god
Yes the female can have it if the father is diseased and the mother is a carrier but this is very very rare..may be if there's consanguinity
I have hemophilia and i am a female so it absolutely can :)
you're egyptian
Yes