An cohesive narrative that makes sense?! Congrats you write notes and explain things better than my lecturer did about this. It confused the hell out of me until I found this. :P
***** Lancaster university. I was as part of my course doing DNA technology. The lecturer did not explain it that well and it took me a while of working out and looking for the best way to understand it.
too bad i can't cite this. i'm working on a paper about genome editing and medical journals are basically unreadable. thank you so much for making this information more digestible. (Edit: I found some journals that I could pick out some information from. Obviously not all of it made sense, but it was enough for me to know what I was doing. This video still helped me on what to look for in my sources. The paper got a good grade.)
This video helped me a lot, you explained it very well! Thank you! There is however a very annoying beep noice in the background, it is kind of distracting. Maybe you could work on that next time?
One thing I am interested in is the exact mechanism by which the desired genes are delivered to a target site? For example, lets say you want to change skin colour or density in a specific part of the body, how does one actually go about applying it? If ZFN is not utilizing a viral catalyst, then what is the (presumably liquid) solution being administered, and is this solution proprietary? Do I have to pay a lab somewhere to create a soup loaded with the gene modifiers I want? Can it be applied directly to the skin to take affect?
Question: does this explain why the therapy (Zinc ionophore +Zinc) could help against COVID19? 🤔 I read our ribosomes can go into hibernation if Zinc finger is missing which make them susceptible to be hijacked by viruses to replicate themselves. And how does copper and zinc work together?🤔 Thanks in advance for any answers!👍
hi, in image you've drawn is upper part of folk different from bottom part? if not can same sequence as above rotate 180 degree and cut some symmetric genome?
8 years passed and your video helps me understand. Thank you 😭😭
An cohesive narrative that makes sense?! Congrats you write notes and explain things better than my lecturer did about this. It confused the hell out of me until I found this. :P
***** Lancaster university. I was as part of my course doing DNA technology. The lecturer did not explain it that well and it took me a while of working out and looking for the best way to understand it.
9 years later and you helped me understand this ! Thank you
This is a great explanation! Much better than trying to decipher it from a figure in a textbook!!
Amazing explanation! I couldn't understand how it worked from primary sources, but you made it clear.
CRISPR/Cas disliked this video
THIS WAS GREAT keep up the good work mate
Absolutely loved this video. Thank you very much from Colombia. 💕
too bad i can't cite this. i'm working on a paper about genome editing and medical journals are basically unreadable. thank you so much for making this information more digestible.
(Edit: I found some journals that I could pick out some information from. Obviously not all of it made sense, but it was enough for me to know what I was doing. This video still helped me on what to look for in my sources. The paper got a good grade.)
Really nice video and a very helpful review before my gene therapy exam. Good work!
i wish i can thank you in person , you helped much with my presentation tomorrow
Thanks, you made this so much more clear to me!
super explaination.It acted as a source for clearing my doubts
amasing talent of teaching
Damn this was really good, thank you so much for making it so concise and clear :D
It's FokI (FOK1) not FokL
Dont wanna sound racist but after listening videos with indian accent, this video made my day
Awesome. Thanks!
What a great explanation!!!
really good, thank you so much for making it
Amazing tutorial!! Have my final paper on recombinant DNA tech you're my saviour!!
One point, its Fok1 and not FokL. Great video otherwise bruv!
Videos this well and clearly explained make me question why i pay for university classes
This video helped me a lot, you explained it very well! Thank you!
There is however a very annoying beep noice in the background, it is kind of distracting. Maybe you could work on that next time?
awsome presentation 👍
This is great. Thanks
Is there any videos about CRSIPER/CAS9.. if there isn't please make one i like your explanation so much
Very helpful 👍
Great! loved this!
ربنا يباركلك يا بن يا ابن جرسايد
This is awesome ,Thank you
nice lecture
You are amazing, thank you!!!!!
Explained well but doesn't zinc finger produces blunt ends and four of them work together instead of two? Am I missing something?
hi thank u for this!!!
One thing I am interested in is the exact mechanism by which the desired genes are delivered to a target site? For example, lets say you want to change skin colour or density in a specific part of the body, how does one actually go about applying it? If ZFN is not utilizing a viral catalyst, then what is the (presumably liquid) solution being administered, and is this solution proprietary? Do I have to pay a lab somewhere to create a soup loaded with the gene modifiers I want? Can it be applied directly to the skin to take affect?
You're the best, thx!!!
Question: does this explain why the therapy (Zinc ionophore +Zinc) could help against COVID19? 🤔
I read our ribosomes can go into hibernation if Zinc finger is missing which make them susceptible to be hijacked by viruses to replicate themselves.
And how does copper and zinc work together?🤔
Thanks in advance for any answers!👍
Thanks!!!
fantastic !
Thank you so much for this video :)
hi, in image you've drawn is upper part of folk different from bottom part?
if not can same sequence as above rotate 180 degree and cut some symmetric genome?
Could you make a "blunt end" DNA break by positioning the endonucleases closer together (making a smaller spacer region) ?
Cheers dude!
Really annoying high frequency noise in this video. Please figure it out.
Thank you so much
Thank you for watching and commenting.
if i were to use the information from this video in a report, what scientific journal/publication could i quote for references?
thank you
that's great!
sorry, but it is the Fok1 nuclease not FokL
Wikipedia and Pubmed disagree. Its Foki with the "i" capitalised.
Is it FOKL? or FOK1?
FOKI (Capitalized i)
Is this what our next vaccine is going to be ?
It's FOK 1!!!! NOT "L" . That's a huge mistake which should be corrected.
basically, you say "basically" waaaaay too much, basically
you may also use "fundamentally", "essentially" or "at heart".
Thanks :)
by the way *Fok1 .... (Fok One)
My gaydar is going off
Every year I have to relearn this bullcrap for my exams. Every year I come across this video and every year I become a little gayer.