Grignard Reagent Reaction Mechanism

This organic chemistry video tutorial discusses how to use the grignard reagent to reduce ketones and aldehydes into secondary and tertiary alcohols. It also explains how to reduce esters and acid chlorides to alcohols using the grignard reagent.
Subscribe:
/ @theorganicchemistrytutor
Access to Premium Videos:
/ mathsciencetutor
/ mathsciencetutoring
New Organic Chemistry Playlist
• Organic Chemistry - Ho...

[@TheOrganicChemistryTutor]

Final Exams and Video Playlists: www.video-tutor.net/

[@user-zq4pw7yr4i]

tnx

[@vedavalliv9597]

The word "thank you" is not enough for your efforts! It helps us a lot! Love from Tamilnadu,India❣

[@thangam5006]

Sis I'm also from Tamilnadu

[@vedavalliv9597]

@@thangam5006 🙌

[@ganeshsriram4941]

You are right, This video is helpful... And I'm also from Tamilnadu...

[@vedavalliv9597]

@@ganeshsriram4941 :)

[@AnkitJosh]

I'm not from Tamil Nadu but I'm from India

[@donaldmusenje5120]

This guy he is a genius he has helped me to understand in all my natural sciences and mathematics. I don't have enough words for him but all I can say is that may God continue blessing with whatever you need in your life. You have helped me personally through out my university life for 4years. Last but not the least please don't stop with what you do continue to help the future generation 💪🙏🙏❤

[@donaldmusenje5120]

From zambia

[@KawaiiBabyTragon]

I needed this so bad last semester, thanks for making it now anyway.

[@meya4307]

So basically, since feb. 2020, you've been my instructor. And THANK YOU SO MUCH.

[@rohanbhide4495]

thankyou for this video! You have selected the best questions and the right amount of questions for this topic! I really appreciate it!

[@cedricchurch3632]

This video jusy came in really clutch for my 1st orgo 2 exam. Really preciate ypur vidoes they helped me through physics too

[@criskris007]

Thank you for all your videos, I passed both organic chemistry courses with good grades because of you

[@theobanai]

Teacher nehi padhate the kya😕

[@sounad3736]

@@theobanai tujhe teacher nehi padhate? Tu yaha kya kar raha hae ghochu?

[@cunningclown7422]

Thanks! Cleared my concept very well!
Great explanation!

[@depharmily2064]

you are the reason i do well in my exams and tests

[@chemchristv]

You are the best.... I want to be like you... Since my year 1 I have been using year video... Now I am a chemistry Tutor I am still watching your videos.. for proper explanation..
Thanks alot

[@rohanbansal2324]

excellent video my man. keep up the great work

[@dianed4938]

you made me fall in love with chemistry through your videos

[@237BrillantBABOKA]

Cette vidéo m'a rendu moins bête 😀, merci beaucoup Monsieur.L'anglais est vraiment très important pour la poursuite des études supérieures, dommage pour moi car je ne comprends pas...( BABOKA, DEPUIS LE CAMEROUN)

[@Shred427]

This vidéos are so well explained, and help a lot to understand more easily the dark side of organic chemestry, so i need to say : Big thanks!

[@neilmashalkar5203]

great video! just some advice- keep the picture of the final product up for a few seconds longer- i can’t pause the video fast enough to see the product alone

[@tomatrix7525]

Thanks man these are really great to watch

[@Megan-je2lr]

you deserve an award of some kind. you are the reason I'm passing my final in 2 hours :)

[@mr.madguy6125]

😂

[@surafeltesfu9953]

you are the most intelligent teacher i ever know !! thanks

[@guiaf_]

Hope you're making millions by now my dude

[@walterblack91]

hope he does....he deserves it totally

[@brianshang1069]

Awesome vid, can't say it enough.I smacked that sub button

[@raphaelkirangole4031]

Thank you for your video 🙏🏽 it is really helping me following from Kenya

[@xxxdarksaskeexxxthesighing9575]

Thank you for your vidéos. You cannot know how much you help me

[@gemlovergirl]

You are the best tutor!!!

[@Frame381]

You are a saving grace! Thank you so much

[@manishjat6263]

nice bhai

[@Naomicool100]

A big „thank you“ from Germany 😇👌🏽

[@ramisamaliath8658]

Omg Thank you!!! This helped a lot

[@nanditasanghvi]

thaank you so so much
you are brilliant and your teaching style is amazing

[@JiyonKim5]

first time i feel like im understanding ochem!!! thank u so much! :)

[@ujjwalkumarsingh5216]

Thanku sir ..I had confusion in this part

[@MoeZokari]

Thank you sir... you are a life saver... wallah

[@shashaniou4]

thanks for your teaching!!

[@samajhdar3853]

Thankyou , your deep explanation is attached to show more than one video and you are show everything in rxn ,what I to do.
India (Hindi)

[@hasanaliameal4298]

Thank you very much I am from Iraq and you help me by this lessons

[@jesusmrosario-claudio4104]

Thank you once again.

[@latte3728]

Thank you for your help!

[@valent9260]

mann..... i wish could hire u privetely as my chemistry olympic mentor

[@patrycjapajdak2491]

A very useful video, thanks!

[@duaamohamed5480]

Am so proud of you

[@user-vj8vp3ti2t]

thanks for all your videos

[@aakashpatel9650]

Great session

[@Ak-ix2xp]

You're such a gem

[@ritankarmondal0411]

Can't thank you enough man! I was facing doubts in grignard reagent and this cleared everything!
And a quick question. For the compound in 9:45 won't a ring expansion be more favourable before the addition of the -R group?

[@ashaydwivedi420]

this is an SNAE mechanism! rearrangement is only possible when a carbocation is formed. this reaction involves carbanion nucleophile and no carbocations are formed, so no rearrangements

[@kushagra5633]

Best explanation ❤

[@DevilMode-pd8el]

Thank you so much sir 💖from TN(India)

[@zincion1]

Great video!

[@aarongurung786]

My man's carrying my entire organic department staff

[@ivertylungu7834]

We really appreciate for your help

[@darkphoenix6742]

Very efficient!

[@ashokkumarsharma5666]

Surely a nice video with good explanation and high order jee leve questions

[@Ihatwpwrsona5]

wdym

[@Lolstarwar]

Helped me a lot thanks

[@cringespot2928]

Thanks from Tamilnadu India 😍😀

[@emmaaustin544]

Awesome! Thank you

[@An_ony_mous]

Thanks alot. Now wherever I see RMgX I won't make mistakes.

[@svenvandeweerd7467]

great explanation!!!!

[@sukrutha8788]

thank you so much for this video! your explanation made everything easy to understand

[@ruq3tuieiotiyiiabyiuoyoppa413]

thank you sir☺

[@manjunatha15madhu36]

This videos is more usfull to us
thank you

[@bailassandijani3788]

could you please make a discussion about Reaction of Grignard Reagents with Epoxides
thank you

[@gautalawrencebusa7474]

Thank you very much.. This is what I need now

[@nevabeenhxted2159]

Denhxv82 5 run to take 8 hours and turn

[@samarthgoswami5289]

Thank you kind sir!

[@alderamin1402]

THANK YOU SIR

[@harshbalhara4389]

Thanks sir !!!!
Great love from INDIA.
You really help me often!!

[@mahdafikia529]

Thank you!!

[@joshuaschamach4684]

Highest grade on my O Chem 1 final. High A in the class. Gracias.

[@gill.guntas]

Very good

[@single-cellshark6013]

Badass. This guy is badass

[@haryanwar1263]

This better than my teacher

[@fourtyfourrr]

thank you so much

[@negar21100]

@7:03 Why didn't O get protonated at this moment? Why did it kick the OCH3 out instead?

[@toxicevolution5940]

Doesnt it matter that you change the position of the CH3 Group in the first example?

[@fantasiaford1283]

So, the Ch3Ch2, we use it twice because we need the oxygen to be negative in order for it to do the proton transfer of hydronium? So it can be an alcohol?

[@yashkalia2311]

Thanks

[@fredt8167]

At 3:35, if we had to name this structure would be it be (A) 1-ethyl cyclohexanol or (B) 1-ethyl cyclopentanol? If its (B), why? when counting the longest chain starting with the ethyl group

[@footy1236]

Thank you

[@CR1257]

How do you know what side to put your reagent on? I keep thinking that you could choose either or because you’ll still end up with the same answer..? 08:26 I’ve seen others put their reagents on the aldehyde side and they’ve gotten it the answer right.

[@LA-cm9uo]

You are an angel

[@naomimascarenhas815]

THANK U

[@amirfilabs7716]

At 12:18 I believe this is an epoxide ring opening under basic conditions so the OH lands on the more substituted atom, please correct me if I’m wrong

[@Code_eat_sleep]

Thanks a lot ...

[@urvitiwari6754]

is attack by GR always SN2? is there a possibility of rearrangement or ring expansion?

[@laurensadowski2403]

9:28 are there supposed to be that many carbons attached to the grignard reagent?

[@fayaraheeb9673]

thank you sooooooooo muchhhhhhhhhh

[@tomiakinsete1716]

God bless you

[@shihab5689]

Love from Bangladesh 😘.

[@magnesiumswift]

really nice

[@antique_key]

Best 👌

[@GoogleAccount-mz6vn]

At 7:14 why didn't the O¯ get protonated and turned into an alcohol instead?

[@sandhyachaudhury956]

Wow! That's all I can say!
Wow!

[@samajhdar3853]

Thankyou

[@billalzerouali4472]

Why is at times the h30+ is written under the arrow and other times it isnt even though its still used

[@mikedavis7636]

What if you created a grignard reagent with bromobenzene and magnesium, then bubbled carbon monoxide through the solution?

[@eyenashfna]

thankyou

[@senorbacon304]

thank you so fucking much

[@ericraululyeetusdelyeetus5028]

Had to go to this video after seeing a legendary meme about the reagent.
Who would've guessed a well edited clip of black'n'white daffy duck would be so funny?

[@juststudy9989]

Hey dude u are OP

[@trentkirkwood4488]

Im learning from these this one just seemed like you were going kind of fast.

[@RotationMan13]

How do you know of the Carbon is partially positive or negative?

[@ujjwalkumarsingh5216]

When carbon is attached to a more electronegative atom like O of N ..the more electronegative atom attracts the shared pair of electrons from the electron cloud towards itself ..so it develops partial negative charge.

[@banny2263]

Love from india

[@mikedavis7636]

Can you also make multiply substituted grignard reagents from muliply substituted benzene, such as Para dichlorobenzene and magnesium.