Diabetes 18, Macrovascular complications of diabetes
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- čas přidán 26. 08. 2024
- Macrovascular disease
Macrovascular disease affects the large arteries. It has been suggested that atheroma formation in diabetes is triggered by glucose levels in the blood being raised over a period of time. This allows glucose to migrate into the inner lining of arterial walls. Harmful low density lipoproteins seem to adhere to tissues which contain higher than normal levels of glucose, resulting in fatty accumulations in the vessel lumens. This process is then developed by higher levels of fatty material in the blood caused by the insulin lack mechanism already discussed.
The presence of fatty deposits in turn leads to the deposition of fibrous collagen and the development of atheromatous plaques.
Whatever the precise reasons, diabetics often develop more advanced atheroma than other people of the same age and sex. The development of atherosclerosis is accelerated in diabetes. Atherosclerosis affects the coronary arteries leading to angina and myocardial infarction. Coronary heart disease is the leading cause of morbidity in people with DM, accounting for up to 70% of deaths. Atheroma in the vessels supplying the brain leads to cerebral ischaemia and possible cerebrovascular accident. In the peripheral vessels atheroma will result in peripheral vascular disease. This leads to ischaemia and possible gangrene (areas of necrosis) in more advanced cases, explaining why lower limb amputations are significantly more common in diabetics compared to non- diabetics. Renal arterial involvement contributes to chronic nephron ischaemia.
Smoking will potentiate the development of macrovascular atheroma so it is particularly important that diabetics do not smoke. Serum cholesterol should be kept at low levels using statins as required. Blood pressure should also be closely monitored and lowered as necessary.
My professor talks for 2 hours not explaining this thoroughly yet a 5 minute video summarized this point way too well, thank you Dr.Campbell
Just fantastic. The best representation of vascular occlusion I've ever seen. Thank you. Mike, RN
Thank you sir, I always watch your lectures because I am a diabetic.
الله يشفيك ويعافيك
i got this when i searched for nicoavocado " that was 18 dollars-- diabetes." meme im dead
Iconic.
Sir u r great I really want to get knowledge by you u r genius and so good
its a great video clip more interesting and helpful to the viewers i like your good explanation and though and its a good guide..
Excellent Dr Campbell much appreciated 👍
God Bless you Sir
Such a wonderful explanation
Even a layman can understand
Thank you sir
This is glorious, been searching for "can you have diabetic nerve pain without diabetes?" for a while now, and I think this has helped. Have you heard people talk about - Piyatalie Breathtaking Precedence - (Have a quick look on google cant remember the place now ) ? It is a smashing one off product for discovering how to get rid of type two diabetes without the normal expense. Ive heard some decent things about it and my m8 got excellent success with it.
Whate a wonder full with a dee p knowledge lecture.
Great explanation!
well done doctor😍
Thank you
Amazing doctor !
I doubt you're still looking at this. But how about pulmonary embolism?
Great! Thank you
loved this very helpful thanks
Dr John Campbell, is there a way we can contact you regarding a diabetes type 1 patient being denied treatment and insulin, food and water, unfortunately this patient is no longer with us due to what they were put through and other suspicious circumstances surrounding the suspicious loss of life.
This patient I speak of is my Dad, I'm hoping to gain as much data as I can on Diabetes type 1 complications.
kind regards
Im sorry you have lost your Dad, tragic. Yes, do tell me more.
@@Campbellteaching thank you, shall I send an email to your website displayed on your CZcams account?
The case is still on going, so to write it on here would not be appropriate.
Yes, you can do@@celynmanchester3053
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"that was 18 dollars"
Words aren’t enough for me to show how I grateful I am for helping me to get rid of my type 2 diabetes Dr Igudia
Cool video. In similar fashion has anybody out there heard of the KmanPlan (just google it)? It is getting wonderful reviews.
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