Berberine - updated
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- čas přidán 1. 06. 2024
- I use and recommend Thorne Berberine: geni.us/KGv7BdO (Amazon)
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In this video you'll discover the nootropics benefits of Berberine. Including the best type of Berberine to buy, recommended dosage, side effects and clinical research.
This Berberine review video is an update to the video on Berberine I published on this channel several years ago.
Berberine is well known and proven for reversing type-2 diabetes. But few people realize how powerful this supplement can be for reducing sugar cravings, eliminating late afternoon energy crashes, lifting brain fog, and boosting memory and mood.
Berberine activates the enzyme AMPK which is the master metabolic switch in each one of your cells. This directly influences lipid, glucose and energy imbalances.
Activating AMPK by adding Berberine to your nootropic stack boosts mental energy, provides quicker thinking, and even repairs and maintains healthy brain cells.
Berberine also inhibits acetylcholinesterase (AChE) activity in your brain. Increasing levels of acetylcholine has a direct influence on better concentration, focus and memory.
Berberine has been shown to be as effective in controlling blood sugar and insulin sensitivity as metformin.
The latest research confirms user experience that supplementing with Berberine can help with depression, help prevent Alzheimer's, help control several types of cancer, lower cholesterol and blood pressure, and help with weight loss.
This indepth Berberine review covers:
00:00 Berberine intro
00:14 Berberine as a nootropic
03:47 How does Berberine work in the brain?
06:05 Berberine benefits
07:32 How does Berberine feel when you take it as a supplement?
09:04 Berberine Clinical Research
15:14 Berberine recommended dosage
16:37 Berberine side effects
18:29 Type of Berberine supplement to buy
For more on Berberine including a full transcript of this video and links to clinical studies, go to: nootropicsexpert.com/berberine/
I use and recommend Thorne Berberine: geni.us/KGv7BdO (Amazon)
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I took myself off Metformin and began taking Berberine exactly one year ago. I combined that with a keto diet, the Wim Hof Method, OMAD, and acupressure techniques. My waistline has gone from 52 inches down to 44 inches. I had no idea about the nootropic benefits. That's good news. Thanks.
Thanks for the report!
Berberine came to my Attention in ‘21
after diagnosed in ‘20 w Type ll diabetes.
It’s a bit pricey, sadly. In my Mid 60’s I had diarrhea, low energy, gained 25lbs and just didn’t feel my active self. That’s All reversed now. 2-3 mile fast walks daily, MSM keeps my joints, ligaments good, ended my Rotator Cuff injury. 🎉 Dihydroberberine 15 minutes before Carb intake. And I use Milk Thistle. Cheers. I feel like an herb/nootropics pharmacy.
I’m on dihydroberberine 250mg which I’m told is 5 times more absorbable than berberine. I also take silymarin. I will start taking it with coconut oil. Thanks for your information.
I like ACV 2 tablespoons Berberine 500mg x2 a day, NAC before bed and Tudca whenever.
Can’t thank you enough for enlightening us man! You sir along very very few others have really helped me understand how the brain and its receptors function and made me somewhat capable of tweaking certain areas which really made a huge difference on me. God bless you!🌹
Thank you. Much appreciated.
Excellent nootropic. I like ancient bliss.
As usual a great video.
Thanks!
Thank you Dave
Thank you John!
Great video as always.
Thanks!
Great video as always. Best wishes.
Thank you Eric. I appreciate the encouragement.
As always another great video- thank you.
Thank you Steve. Much appreciated.
Greetings David, thank you so for this very valuable information. I am taking BerBerine now and hoping for the very best. I have also purchased Head First. What a wealth of knowledge, you’re the best. Thanks again for everything.
Nice explanation
Thank you Sehrish!
I have tinnitus from either theJ and J vaccine , long covid and or chronic Lyme
I have been using Berberine (250mg ) before dinner and have been improving
I did find information about Berberine treating chronic Lyme
Perhaps because it’s an antibiotic
I’m finding that my blood sugar does not spike as much upon waking also
Thank you for yet another very informative video.
Thanks!
Thank you very much for this update. Very interesting that Berberine is an MAO inhibitor, which is needed to help with toxoplasma gondii, plus it has the ability to remove other parasites by breaking up biofilm.
Berberine is a great supplement.
I'm really injoying berberine for the weightloss effect I was 104 kilos now at 90kg can allso feel lift in mood mine has Ceylon cinnamon in it .definitely can fast with it was never a suger sweet lover more savoury lover. Thank you for the update really injoy your utube videos.
Thanks for the report James.
Thank you, this is the first I've heard of the additional benefits of berberine in relation to dopamine and serotonin. I have rather extreme ADHD and was wondering if this should be stacked with any other supplement to boost dopamine and if so, are you able to recommend something in particular? Great information, thank you.
Ally, you could but far better options include Saffron and Maritime Pine Bark Extract. I have videos on this channel for both.
Hi David, what are your thoughts on using berberine as a preworkout? The increase in catacholamines would be nice, but I hear it reduces some of the beneficial adaptations of exercise - particularly increases in VO2 max. I'm not sure if Metformin does this and berberine doesn't. I don't have any issues like diabetes, I'm just in it for the stimulation effects. Thanks for all you do! I learn a lot from you.
Jacob, I don't think you would get any special benefit for your workout from using Berberine. There are other better options as a pre-workout supplement.
Hello David, first, want to say that I've been immensely educated regarding nootropics as a result of your videos. What I'd like to know is can Berberine hcl and reduced Glutathione be taken together? Thanks in advance for your feedback.
Lynn, as long as they both work for you they can safely be used together.
Thank you so much for finding all this info. 500mg 3 times a day is for concentrated berberine. If we use oregon grape root or other whole herb with berberine, how much would suggested doese would be?
Berberine is an alkaloid extracted from plants. It is not 'concentrated'.
But if you wanted to get your Berberine by using Indian Barberry (tree turmeric) or Oregon Grape you'd need to send it to the lab and have it tested to know how much Berberine you were getting.
And that amount would vary depending on where it is grown, how it is harvested, the time of year it is harvested and several other factors the are needed to produce this alkaloid in each plant.
You said that people with heart problems should ot take Berberin. However i see tons of studies that say that it helps with heart problems, and is as efficient for lessening arrhythmia(especially combined with C & D vitamin, along with magnesium), also it greatly reduces atrial fibrillation, and is as good or better than the best known drug for it(which has nasty side effects). Very good results on treating congestive heart failure, and this has been verified in a lot of studied. In general if somoene has these heart problems its good to take Berberin, not something you should avoid.
When exactly did I say someone with heart problems should not use Berberine?
What about dihydroberberine?
Joe, dihydroberberine is an extended release form of Berberine which is supposed to make it more bioavailable. Clinical studies from the looks of it don't back that claim up.
Since berberine stops the breakdown of choline should this be cycled, like huperzine a?
If I was using this just for fat loss would you recommend the same dose of 500mg x3?
Berberine is an acetylcholinesterase inhibitor but NOT on the same level as Huperzine-A. It has a short half life which is why you need to use 500 mg 3-times per day to get its full benefit.
Same dosage for whatever you are using Berberine for.
But berberine increases liver enzymes. I want to take it but have NAFLD and overweight. What shall I do? My doc has no clue about it.
Berberine does NOT increase liver enzymes. Please read my full review here including the Side Effects section: nootropicsexpert.com/berberine/
Fascinating information. I’m T2 diabetic, is it safe to take this whilst fasting? I’m currently taking a capsule of Berberine 500mg +Turmeric+Black pepper once a day.Thank you.
Paul, it shouldn't be a problem.
I just started it today. I got hot and itchy very quick but it passed. I also took the full dose and a Whole Foods energy shot. So I don't know which cause the itchy hotness. If you take an SSRI like Lexapro ok?
Kym, chances are high that it was the energy shot that caused that. Berberine will lower blood sugar and blood pressure however. But it is not contraindicated with SSRIs.
Great stuff as usual, I only eat twice a day as I do Intermittent fasting. How can I take 3 capsules per day? Can I take it without a meal?
Youssef, Berberine is water soluble so it doesn't matter if you use it with a meal or on its own.
Hello David, may I know if you are interested in trying PEMF(Pulsed electromagnetic field) devices? DHA is highly synergistic with frequencies like PEMF.
If you have an affiliate program I am definitely interested in trying it. Pls. send me an email [david (at) nootropicsexpert.com]
Would yu provide searchable references for the studies cited?
I cannot include them here on CZcams because CZcams only allows me so much space for notes. But every video review of a supplement includes a link to my website in the notes section. Those reviews on my website contain dozens of clickable links to peer-reviewed clinical studies for each supplement.
Interesting, can i use it before bed or in a morning, pls? can i share it with my cats?
You need to use 500 mg Berberine morning, noon, and then again late afternoon to get its full benefits. As for your cats, you'll need to check with your vet.
I don’t have diabetes or pre-diabetes. I was interested in berberine for weight loss and some of the other benefits. Is it ok to take it everyday longterm? Does it need to be cycled? Thank you.
Berberine is safe to use long-term for pre-diabetes just like Metformin. I like taking it with Milk Thistle extract because it can be hard on your liver if used long-term. Milk Thistle helps negate those effects,
Did they use berberine hcl for thousands of years surly it was the bark or fruit?
Plants containing Berberine have been used in traditional Ayurvedic and Chinese medicine. They did not have the technology that we have today to extract individual compounds from these plants. But they were wise enough to know and use the plants that contained the highest amount fo berberine.
Is it safe to take if I am already taking an MAO-B inhibitor (Rasagiline)?
Deb, Berberine inhibits cytochromes P450 (CYP3A4, CYP2D6 and 2C9) in your liver. So find out if the drug uses any of those to metabolize that drug. Because it can cause a substantial increase in the bioavailability of certain drugs and nootropics. Which can be dangerous.
Does it help in eliminating bad bacteria from the gut?
It helps keep Candida under control.
Is Berberine good for fatty liver disease
Yes, according to this study: www.ncbi.nlm.nih.gov/pmc/articles/PMC9459907/
What kind of Milk Thistle is good to take with Berberine
This is the one I use: geni.us/Vfo1C
Do you take it on an empty stomach?
Cindy, Berberine is water soluble so you can take it with or without food.
How do researchers evaluate the mood of mice? 🤷🏻♂️
www.frontiersin.org/articles/10.3389/fnbeh.2022.931964/full
What doesn’t it do?
Dain, I can think of a few things it cannot do. But go back and listen to the section called "Berberine benefits" for its biggest benefits.
Why were you insulin resistant?
Diet overweight and sedentary
Not sure but likely being overweight and eating the wrong foods contributed to it. I'm sure there is a genetic component involved as well.
But using Berberine 500 mg 3-times per day soon normalized everything. And my labs (including yesterday) are normal and within range.
I think I’ll give it a miss🙁
James, Berberine is not for everyone. Just like any of the other supplements I review (and use). Some work and some don't for each person.
wtf u saying about using milk thistle and berberine?
it's unclear
Dan, go back and listen to that section of the video again. Or read the original transcript.