Ramachandran Principle: Protein Atomic Clashes vs. Phi & Psi

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  • čas přidán 9. 07. 2018
  • Animated atomic models illustrating Phi and Psi dihedral (torsion) angles in proteins, and how atomic clashes make certain angles impossible, favoring the secondary structures of alpha helices, beta sheets, and turns. Clashes are shown forming in real time as phi or psi rotate. Related resources:
    -- Quiz (9 questions): proteopedia.org/w/User:Eric_Ma...
    -- Slideshow: tinyurl.com/RamachandranPrinciple
    -- Interactive 3D tutorial with rotation controls:
    -- bioinformatics.org/molvis/phipsi or
    -- proteopedia.org/w/Tutorial:Ram...
    -- Other Ramachandran and Phi/Psi Resources: proteopedia.org/w/Dihedral/Index
    EN ESPAÑOL:
    -- Cuestionario: proteopedia.org/w/Dihedral/Ram...
    -- Presentación: tinyurl.com/PrincipioRamachandran
    -- Otros recursos: proteopedia.org/w/Dihedral/Index
    The RAMACHANDRAN PLOT shown excludes glycine, proline, and pre-proline. Those other plots are available at en.wikipedia.org/wiki/Ramacha...
    Also recommended: Understanding PHI and PSI Angles, Ramachandran Plots, & Newman Projections -- • Understanding PHI and ...

Komentáře • 124

  • @marksteve8373
    @marksteve8373 Před 5 lety +112

    The best Ramachandran plot video out there! Many thanks!

  • @singing.winnie
    @singing.winnie Před 3 lety +21

    Wow. Just wow. I’ve been struggling to imagine these angles with my head nor by looking at the textbook. This solved the problem!!!!!!! Thank you so much!!!!

  • @nabarunr3
    @nabarunr3 Před 3 lety +2

    Noting but gratitude to you, SIr. And the best part is you enable teachers to present this material, and they can choose not to mention your name. This is truly what open knowledge is, and it cannot come from small minds. I'll strive to achieve this kind of mindset. Thanks a ton.

  • @m.t1446
    @m.t1446 Před 5 lety +1

    Best explanation of Ramchandran plot on youtube. Bless your soul!

  • @nancysong9581
    @nancysong9581 Před 4 lety +2

    The first time I actually understood Ramachandran plot and the phi and psi angle!!! (I first came across it during first year uni and now I have graduated) It's so hard to understand without animation. Thanks a lot!!!!!!!!

  • @leahdavis6265
    @leahdavis6265 Před 3 lety +14

    I just want to say here because I don't think this is mentioned enough but this video is perfect for visual learners and especially students with ADHD. This is definitely the best ramachandran plot video and visualization I have seen!
    P.S. I am a BME PhD student with ADHD who came in with a non-biology engineering background currently thrown into graduate biochemistry so if this 1 video can bring a part of an entire biochem course chapter together then you deserve to know how awesome this is!

    • @ericmartz9100
      @ericmartz9100  Před 3 lety +3

      Thank you so much for your insight about ADHD learners, Leah. Good luck with your graduate work!

    • @abhishektripathiii
      @abhishektripathiii Před 5 měsíci

      True :)

  • @ambar9232
    @ambar9232 Před 4 lety +1

    Great explanation and the best thing about it is the 3D Animation which sets it apart from the other videos.

  • @rialc6238
    @rialc6238 Před 3 lety +2

    The visualizations really helped understand this topic. This is just what I needed. I wished textbooks would have explained as you did. Thank you sir!

  • @ojaswibiswas6
    @ojaswibiswas6 Před 4 lety +3

    I never understood this concept so well. Thank You so much this is the best possible explanation.

  • @teresavillalaz1779
    @teresavillalaz1779 Před 2 lety

    I've read infinity of books and nothing was better explained than this! Great work, keep it up!

  • @Tanya-xl3oy
    @Tanya-xl3oy Před 4 lety +4

    Wow. this video was perfect! i can confidently say i understood everything in this video having no prior knowledge. thank you!

  • @mauriciomrable
    @mauriciomrable Před 5 lety

    Thank you for this video and all the support material. Amazing!

  • @shivi3132
    @shivi3132 Před 15 dny

    Thank you so much for making this, i was beginning to think id never understand phi and psi angles, after your video i was left wondering why i thought i couldnt

  • @00metta00
    @00metta00 Před 5 lety

    Absolutely sublime video; concise and coherent. This has really helped me with my understanding of these plots. Thank you so very much 🙂

  • @soumilibera8282
    @soumilibera8282 Před 3 lety

    The best video on Ramachandran Plots . I really want to thank you for this. I was really struggling with this . Thank you so much

  • @ionapay6681
    @ionapay6681 Před 3 lety +1

    This was incredibly helpful, thank you so much for creating this!

  • @Erik-um7hq
    @Erik-um7hq Před 4 lety +1

    A fantastic an easy to understand illustration. Good Work!

  • @kiruthikabalasubramani8874

    It can't be more better than this explanation...I struggled imagining all those angles.. Now I got it...Thank you sir

  • @james4727
    @james4727 Před 6 lety

    the animation makes it so much easier to understand, thank you for the video :)

  • @jessicalv6442
    @jessicalv6442 Před 9 měsíci

    Can't live without this video! Saves my life thanks!

  • @nanosciencebyjalal3793

    it's not fairrrrrrrrrrr , your channel must have millions of subscribers, you are a genius

  • @helenc40
    @helenc40 Před rokem

    I understand Phi & Psi at last. Thank you! This is the best explanation I've seen.

  •  Před 5 lety

    it's the best explanation about Ramachandran plots !. Thanks ever so much !

  • @2361243
    @2361243 Před 3 lety

    This is truly amazing.Nice animation. Thank you so much.

  • @Tiago211287
    @Tiago211287 Před 3 lety

    This was an excellent lesson on basic biochemistry. Loved it. Thanks for this.

  • @okpolihenry983
    @okpolihenry983 Před 3 lety

    OH MY GOD , JUST WOW . I HAVE BEEN STRUGGLING TO UNDERSTAND THIS TOPIC FOR DAYS UNTILL I CAME HERE . THANK U SO MUCH

  • @nanosciencebyjalal3793

    it was the best of Ramachandran i've ever seen

  • @noorakhtar5536
    @noorakhtar5536 Před 4 lety

    exceptional thank you so much! love the links to resources as well; very useful

  • @neellohitsarkar9183
    @neellohitsarkar9183 Před 3 lety

    @Eric Martz lifesaver!

  • @joshuawhittick4496
    @joshuawhittick4496 Před 3 lety

    great video, love the visualisation of steric clashing

  • @abhiramips
    @abhiramips Před 4 lety

    The video is very concise and informative. Thank you for that!

  • @janbrezovsky2227
    @janbrezovsky2227 Před 3 lety

    Wonderful work! Many thanks for your work.

  • @auroshikhamohanta1087
    @auroshikhamohanta1087 Před 2 lety

    This video is amazing to correctly imagine the rotation of torsion angles. It really helped a lot. thank u so much for making this video.

  • @mahamali605
    @mahamali605 Před 5 lety +1

    Best most clear and concise explanation . Many many thanks Sir. :]

  • @nataliepopielski1125
    @nataliepopielski1125 Před 3 lety

    Thank you! This clarified much of how this works for me!

  • @bioethno3219
    @bioethno3219 Před 5 lety

    Thank you for this video, I understood this part of my course thanks to you!

  • @lorbasaurus2000
    @lorbasaurus2000 Před 5 lety

    Great visuals and explanation!

  • @qn9cmo0kjoi9
    @qn9cmo0kjoi9 Před 2 lety

    Thank you sir so much for making this video! It's the best on CZcams. So nice and clear! Big thanks from Taiwan. May God bless you and your love ones!

  • @majakornaj2264
    @majakornaj2264 Před 3 lety

    great video! really helped me understand the concept. thank you so so much!

  • @mayanksangam9205
    @mayanksangam9205 Před 3 lety

    This is fantastic and really helpful. Thank you.

  • @yongshancelinene-eh1165

    What a great video. Thanks for the content

  • @slimmathers5665
    @slimmathers5665 Před 2 lety

    WOW. Amazingly done.

  • @mvcnj9700
    @mvcnj9700 Před 4 lety

    Really the best video help visualizing the dihedral angles.

  • @vahid8050
    @vahid8050 Před 2 lety

    Very interesting and clear to understand, thank you.

  • @verteeger
    @verteeger Před rokem

    Thank you for this video with the visualisations and great explanation of what we are looking at! I feel a little bit enlightened :D Thanks again!

  • @vipulkumar7035
    @vipulkumar7035 Před 4 lety

    Very nice video. Keep up the good job.

  • @javaidchoudhary4653
    @javaidchoudhary4653 Před 5 lety

    I watched lots of videos on Ramachandran plot but none of them make me understand . Thanks a lot sir for this well explanation. Plz make some more videos on protein structure and chemical bonding we shall remain thankful to you

  • @tushardhyani9007
    @tushardhyani9007 Před 5 lety

    Best one on CZcams for the plot

  • @PraneetPaidisetty
    @PraneetPaidisetty Před 4 lety

    This video made it so easy to understand.

  • @abhishekchatterjee1709

    Very nice demo. Thank you!

  • @saumya4655
    @saumya4655 Před 3 lety

    Ty for the video. The quiz was also helpful!

  • @johnl6361
    @johnl6361 Před 5 lety

    Thank you so much for this video!

  • @suprajaganganapalli5880
    @suprajaganganapalli5880 Před 4 lety +1

    thank you for the video really helping to understand concepts i have seen many videos and books to understatnd it bu t i felt better

  • @jayamalwanniarachchi1437

    simple and amazing explanation.. Thnak you sir

  • @jessicamartins7544
    @jessicamartins7544 Před 3 lety +1

    Great explanation! Thank U so much!

  • @soumendash3911
    @soumendash3911 Před 2 lety

    Hey, I dint know how or thank you this is really amazing I have never seen someone giving a test after a lesson on youtube really happy for that Nice explanation too. Good start to my day.

  • @Biocreator
    @Biocreator Před 3 lety

    best Ramachandran plot video on youtube

  • @anjaligupta6180
    @anjaligupta6180 Před 4 lety

    thank you soooo very much sir...i express my heart felt gratitude to you for making this video....its a saviour....!! thanx a tonn....love from india🙏🙏

  • @b.b.bhattarai9198
    @b.b.bhattarai9198 Před 6 lety

    Good explanation. Easy to understand

  • @shruti.7660
    @shruti.7660 Před 2 lety

    Thank you. I was so confused with the understanding of phi and psi angles

  • @siniorashani
    @siniorashani Před 4 lety

    That was indescribable , thanx very very much

  • @goliadkin830
    @goliadkin830 Před 6 lety

    Very good explanation! Thanks!!!!!

  • @michellearchuleta7881
    @michellearchuleta7881 Před 4 lety

    Amazing video! Thank you.

  • @giammarcoferrari1738
    @giammarcoferrari1738 Před 3 lety

    Thank you very much. I have no other words.

  • @sameloliveira6169
    @sameloliveira6169 Před rokem

    Thank you, my teachers could never explain it better.

  • @subha_jit_roy
    @subha_jit_roy Před 7 měsíci

    Best explain video in youtube after saw many video

  • @amirkiamehr1073
    @amirkiamehr1073 Před 3 lety

    This is awesome !! , Thank you so much !!!

  • @JP11994
    @JP11994 Před 5 lety

    Amazing explanation thank you

  • @user-sm3oq4lc9f
    @user-sm3oq4lc9f Před 5 lety

    thank you so much. it was very helpful.

  • @navidhoseini8680
    @navidhoseini8680 Před 5 lety

    thanks you very much. the best explanation...

  • @amirkiamehr627
    @amirkiamehr627 Před 5 lety

    So helpful especially the simulation

  • @tamer4456
    @tamer4456 Před rokem

    great explanation thanks a lot.

  • @elississy177
    @elississy177 Před 10 měsíci

    awesome video !

  • @paulinbarajpillai3569
    @paulinbarajpillai3569 Před 4 lety

    Thank you very much very clear explanation

  • @spkm4tube
    @spkm4tube Před 3 lety

    I hope, my teachers had this kind of tools and willingness to make this concept so much clear. BUT I WILL SHOW THIS TO MY STUDENTS AND TRY MY BEST.........

  • @gokcezora2575
    @gokcezora2575 Před 3 lety

    Thank you, better understanding now

  • @durgamthirupathi1838
    @durgamthirupathi1838 Před 4 lety

    Wonderful video

  • @sunghjung9621
    @sunghjung9621 Před 4 lety

    Love the visuals

  • @sofiapallais6479
    @sofiapallais6479 Před 4 lety

    Excelent! Thank you so much!

  • @vanessakeating
    @vanessakeating Před 5 lety

    Awesome video!

  • @geetarautela1
    @geetarautela1 Před 5 lety +1

    Nice explanation👍👍👍👌👌👌👌☺️☺️☺️☺️thank you sir

  • @sarahihernandez5434
    @sarahihernandez5434 Před 3 lety

    I was completely discouraged because I wasn´t unable to understand this but now I realized how it works, thanks a looooot! Cheers from México.

  • @mayadaahmed2094
    @mayadaahmed2094 Před 5 lety

    very helpful video thank you soooooo much

  • @zayilsalazar5749
    @zayilsalazar5749 Před 3 lety

    Thanks, I finally understood it!

  • @arefsalehi2821
    @arefsalehi2821 Před 3 lety

    That was amazing!

  • @damh7621
    @damh7621 Před 4 lety

    Super helpful! Thanks.

  • @_toom
    @_toom Před 4 lety

    Thank you!

  • @brnkaik
    @brnkaik Před 3 lety

    Thank you very much!!

  • @MrMigzz29
    @MrMigzz29 Před 3 lety

    Amazing!

  • @abhisheklakhera8322
    @abhisheklakhera8322 Před 4 lety

    thank you so much !

  • @anupammishra5443
    @anupammishra5443 Před 3 lety

    Good visualization

  • @bikrammajhi7278
    @bikrammajhi7278 Před 3 lety

    thank you sir

  • @KidScipio
    @KidScipio Před 3 lety

    excellent

  • @narendra5769
    @narendra5769 Před 9 měsíci

    Pls upload more video with animation thanks ❤

  • @benleohollis
    @benleohollis Před 4 lety +2

    4:40 is the most satisfying thing I've ever watched

    • @ericmartz9100
      @ericmartz9100  Před 4 lety +5

      Thank you. It was fun to do. I knew for years that it was possible to show the clashes forming dynamically. Since nobody else did it, I finally got around to it.

  • @rialc6238
    @rialc6238 Před 3 lety

    Sir, could you please tell where in the Ramachandran plot do beta turn conformations (type I and II) and conformations of unfolded proteins lie?

  • @sweetyroy6890
    @sweetyroy6890 Před 4 lety

    Thanks

  • @stipepavic843
    @stipepavic843 Před 3 lety

    best video !

  • @fontexstudios
    @fontexstudios Před 2 lety

    Thanks for the video Eric. What program did you use to animate the bonds with electron clouds and the clashes? very nice to visualize.

    • @ericmartz9100
      @ericmartz9100  Před 2 lety +1

      I'm sorry I forgot to credit Jmol. All molecular graphics were done with it: Jmol.org.

  • @Zunnuarya8047
    @Zunnuarya8047 Před 4 lety

    Very well