I love the way she just listens, she doesn't keep interrupting him trying to show off her own intelligence like so many interviewers do. Awesome information.
It's because she doesn't know anything. Ha ha. Gotcha. As you said, she's a great interviewer and much better than a few other "scientist" podcasters. I can say who, but ppl will think I'm a "hater", so I won't, even though it's just a genuinely honest experience/observation.
Seriously, thank you so much Dr. Patrick. After listening to your podcast I’ve lost 45 pounds. My life is filled with energy and I feel like I have a new lease on life. You are such an inspiration and we are all lucky to have you as a resource. Thank you so much again and I’ll never give up my broccoli sprouts!
I live in Southern California in an off the grid community, I've been growing broccoli sprouts from fall to spring, it's too hot in the summer. I also have a moringa tree, every part of the tree is edible. My goal is to create a food oasis through permaculture. Funny, I do dehydrate a variety of lettuce, spinach, kale, green beans, okra, blueberries, raspberries, strawberries, pomegranate, cherries, mango....also I have a desert peach tree, fig tree, a palm date, a Palo Verde tree, 2 mesquite trees, an orange tree, a lime tree and an apple tree. I can easily dehydrate all of this and I make jerky from the chickens and turkeys I raise. I feed them wheat grass sprouts among other sprouts and forage like purse lane. I mostly stick to a keto diet, I've reversed diabetes and lost 75 pounds. I feel younger at 46 than I felt at 26.😁 Learning about the science of nutrition is like my religion. ❤
Oh Lord, my God, When I in awesome wonder Consider all the Life Thy Hands have made. I study the cell. I graph the complex pathways. Thy wisdom throughout the human body displayed. Then sings my soul, My Savior God to Thee, How great Thou art. How great Thou art. Then sings my soul, My Savior God to Thee, How great Thou art. How great Thou art. I personally sit in silent awe every time I listen to these chemists, biologists, MDs, and researchers on CZcams. First in awe of their knowledge, of course. But then at the incredible complexity of the physical system we still are so far away from understanding. But I believe one day we will grasp its full complexity, as God intends we should.
Rhonda has an incredible ability to slice through all the jargon and layers and find out how something can benefit the health of people. I am thankful to have someone like this to give us this valuable information.
I watched a lot of videos with Rhonda Patrick. She is so remarkable to listening the people like here to Dr. Jed Fahey or Dr. Bruce Ames, as if she is in a constant flow like once Mihaly Csikszentmihalyi described. One can feel that she has a fulfilled professional life and is very happy being in that environment. My congratulations to her and all the successful videos she posted..And many thanks.
In this 2-hour and 30 minute interview, we discuss... • 00:00:00 - the early history of sulforaphane research, including key initial discoveries. • 00:00:37 - the serendipitous unfolding of events that lead to the converging of the research on the NRF2 stress response pathway with the sulforaphane-related research going on at the same institute Johns Hopkins. • 00:05:06 - why cruciferous vegetables bother to create isothiocyanates in the first place. • 00:07:26 - the involvement of the heat shock proteins, in addition to the increased activity of Nrf2, as an additional cellular response mechanism that's been observed in association with sulforaphane. • 00:08:11 - how sulforaphane affects a diverse array of biochemical processes from glutathione synthesis to elimination of reactive oxygen species and detoxification of harmful compounds, including carcinogens. • 00:15:01 - whether or not to cook your cruciferous vegetables. • 00:15:34 - the epidemiological (associative) evidence that cruciferous vegetable consumption may help reduce the risk of cancer. • 00:18:30 - the extremely unpredictable nature of endogenous conversion of glucoraphanin (the precursor) into sulforaphane between person to person. • 00:22:14 - practical information surrounding supplementation of sulforaphane. • 00:27:05 - the effect one particular french sulforaphane supplement had on the doubling rate of PSA, which is a marker for prostate cancer recurrence in prostate cancer patients. • 00:28:17 - the role that the Cullman Chemoprotection Center at Johns Hopkins has played, in addition to fundamental research, in providing early, vital infrastructure enabling some of the efforts of the international research community in elucidating the effects of sulforaphane and related compounds and the underlying biological pathways. • 00:28:26 - the incredible, almost geometric growth in new studies that has occurred since the advent of a few of the key discoveries about sulforaphane and its method of action. • 00:32:48 - the practicality of probiotics as a way to improve endogenous myrosinase activity needed to convert the precursor to sulforaphane into the bioactive sulforaphane. • 00:33:26 - the involvement of our gut bacteria in our ability to convert the precursor of sulforaphane into its active form. • 00:37:13 - whether or not endogenous myrosinase activity improves as a function of repeated challenge with glucoraphanin (the precursor to sulforaphane). • 00:39:30 - why probiotics may vary in their degree of efficacy. • 00:43:00 - why consuming isothiocyanates to reduce the number of bacterial colonies of h. pylori, a risk factor for peptic ulcers and stomach cancer, may turn out to be a better intervention than complete eradication of the species with antibiotics. • 00:47:21 - the bizarre relationship h. pylori has with childhood asthma, where it has been shown that having some h. pylori seems to reduce asthma incidence in childhood. • 00:52:28 - the effect sulforaphane has on inflammation and why inflammation is often a great therapeutic target for many different diseases, including diseases of aging. • 00:54:05 - the life extension properties broccoli has been shown to have in an insect model of aging. • 00:59:27 - the underlying causes of Hutchinson-Gilford progeria and the promise sulforaphane may hold for this disease of rapid aging. • 01:09:00 - the effects of sulforaphane or Nrf2 activation on diseases of the brain, such as autism (human evidence) and Alzheimer's (animal evidence), possibly through anti-oxidative or anti-inflammatory effects. • 01:11:09 - the so-called autistic fever response whereby autistic patients report a sudden reversal of symptoms during brief periods of fever. • 01:10:05 - the role heat shock proteins might play more broadly in the prevention of certain neurological diseases. • 01:19:00 - the challenges inherent in clinical trials where scientists may be extremely optimistic about the effects that might be observed, but still have to exercise caution and choose trial conditions that may be conservative, for the good of the people whose lives and hopes hang in the balance. • 01:27:01 - the role of inflammation and depression and what some studies on animals have demonstrated in terms of sulforaphane's potential as an antidepressant. • 01:42:30 - a special isothiocyanate-containing plant known as Moringa or sometimes referred to as the drumstick tree or the horseradish tree. • 01:46:32 - Dr. Fahey's inadvertent foray into the consumption of exotic meats during a visit to Africa. • 01:51:15 - a compound commonly associated with broccoli: indole-3-carbinol and its downstream product diindolylmethane (DIIM). • 01:57:00 - the practicality of using mustard seed powder as an extra source of myrosinase, possibly for your cooked cruciferous vegetables. • 02:00:13 - whether or not it makes sense to freeze broccoli sprouts in order to extend their shelf life, and possibly even increase sulforaphane within certain contexts. • 02:05:25 - Dr. Fahey's thoughts on where endogenous conversion of glucoraphanin occurs in the body, as well as how long it takes before sulforaphane metabolites hit the bloodstream after ingestion. • 02:07:25 - Some general thoughts on frequency in terms of how often one might need to take sulforaphane to elicit its biological effects. • 02:12:16 - why sulforaphane may one day be a component of sunscreen. • 02:12:31 - what some of the upcoming trials involving sulforaphane are at the Cullman Chemoprotection Center. • 02:17:07 - the incredible way in which a sulforaphane-rich broccoli sprout beverage was shown to dramatically enhance the detoxification of benzene through excretion: one study showed up to 61% starting immediately after supplementation.
Your sulforaphane videos have turned me into a health geek. I'm blown away by this info! Even bought broccoli sprouting kits for my friends and family and forced them to watch some of your videos.
I've been doing my own trial for almost a year with broccoli sprout capsules twice a day while undergoing chemotherapy once a week and can report that my stage IV lung cancer has currently been arrested so far. I'm not sure if it's the broccoli or the chemo but I'll keep on doing both till I find something better or cancer continues to grow again.Thanks, Doc, I'm watching you and trying to learn and understand all those big words you say so I can later look them up and try to save my own life.
Loved all the helpful information but particularly the part on Moringa that started at 13:15 and then again at 1:33:58! As a holistic nutritionist I completely loved the material on gut microbiome as well!
I am very interested in this, since I've had 2 surgeries for bladder cancer (8.5 yrs ago). At 63 now, I want to stay healthy (who doesn't??). I'm also treating my gut biome with fermented milk which has really helped. I was on antibiotics for 14 yrs for rosacea; my dermatologist finally found a topical med that works great. I've grown sprouts before, so will probably add the brocc sprouts to my salads and smoothies.
Brenda Wollenberg Moringa is also called horseradish tree. The peeled root is very pungent, but has proven to be unhealthy if too much of the grated root is eaten or eaten too often.
@@pearlas6943 Yes. I went to purchase moringa on Amazon. Upon reading the reviews, each brand has many reviews that are people saying they got violently ill. Including a brand the expert mentioned in another video.
What a genuinely nice and knowledgeable man!? The interview is so long and it just keeps striking me how he is so pleasant and so careful in laying out his arguments and sharing his immense knowledge! He has a great voice too. :-)
Thanks for another incredibly informative and deeply interesting interview. This was the best I've seen (and you've done many that are truly great). Dr Fahey is a wonderful person - thoughtful, sensitive, poised...and has impressive and vast knowledge. You too are a wonderful woman Rhonda. Thanks for sharing your work. You are doing a great service to the many people dedicated to enriching their lives - although I must say, at least in my case, distracting me from the work I should be doing. Your interviews are too damn interesting not to watch.
Dr. Greger talks about ways to cook broccoli after chopping it so that the conversion to Sulfuraphane happens before cooking it. Or eating a little raw with your cooked to maintain the enzymes needed for conversion
I never watch a 2 hr video on CZcams but this was well worth time spent. Thank you both for this valuable insight. Please do more videos on broccoli sprout SEEDS.
What a great interview and what a nice guy, really down-to-earth and dedicated to his work with the ultimate purpose of doing good for people. Thanks Rhonda for what you’re doing, now back to eating those sprouts.
Awesome interview. I was particularly struck by Dr. Fahey’s apparently high level of self-awareness and communication skills (e.g. he communicates very efficiently with little filler words and provides helpful sentence cues about where he intends to move the conversation).
I'm 53 and have eaten a lot of sugar over the years and about 30 pounds overweight and as a programmer use my brain non-stop all week. So over years the brain fog has built up and just a couple weeks into getting lots of sulforaphane I can tell a huge difference in brain clarity. This substance may not help a young person much but if you are older I would sure recommend it!
Thanks Dr. Patrick, and I have been working on sulfur deficiencies after viewing Dr. Seneff's work, along with yours. Would never meet these Dr.s of Science if it was not for you ...Big fan ..Also, the equatorial and tropical diet, in fact does have fruits available year around, but nothing like the "Sweet - Less Bitter" we have hybridized. 70 Going On 10
Apparently the broccoli seeds contain an anti-metabolite: erucic acid, which inhibits the absorption of the glucoraphanin. Therefore it's not a good idea to consume the seeds directly. The acid is broken down during the sprouting process.
i dont think its true. erucic is not inhibitor, but it is just "proven" to cause heart problems in mice, and was never proven to damage humans in anything
It's cool how now everyone can speculate together and comment and share to grasp these overly complicated systems into manageable and hopefully useful ways. Thats crazy about the fever study. I just assumed "fevers" were a reaction to pesticide on processed and store bought food but to truely understand how all these compounds interact and commune is really cool. I normally don't like scientist and doctors but I like these two curious and smart people. They are sticking their necks out even making these videos
Rhonda I love your videos. Please don't ever stop. I love how much effort you put into them, from the definitions of terms to the time links to specific topics discussed. Yes yes yes
Thank you so much - extremely informative and has reignited my interest in moringa products - and of course the various pathways involved with broccoli sprouting and the goodness thereof - it is amazing to me why I and others have not taken to growing broccoli sprouts every day since there is now such a wealth of information as to how healthy it is for us - (and for such a modest output) - thanks to you and Dr. Jed Fahey who make it so understandable and interesting!
Thank you for the work that you do in editing these videos. The time stamps for the topics are nice but I imagine you did that as a way to maximize your own understanding of the information shared with you during this very rare encounter ;). Also, overlaying the commentary with the relevant data really puts into context what he's bringing up and helps in grasping what he's discussing. It helps too, that he talks in a very understandable manner.
Great webinar Dr. Patrick and Dr. Fahey, we need more people like you ! I love details, Dr. P asked awesome questions I would have asked. I’ve been sharing your podcasts
Thank you for the simplified explanations and extra info at the bottom of the screen Rhonda! Awesome interview. Thank you Jed & Rhonda! Keep fighting the good fight :)
Thanks Rhonda dear for your wonderful podcast ! It has opened my eyes and Horizon on the multiple Health Benefits of the Mooring which I planted in my backyard & consuming fresh Broccoli Smoothies !👍🌈David🌈
I have a supergreens suppliment of kale, moringa, and wheat grass, I get high when I consume some. I kid you not, the feeling is almost instantaneous, light headed and feeling happy.
Thank CZcams! I can’t imagine having to listen to all of these scientists, professors, and doctors on 1X speed! Always at least 1.5X, but if possible, 2X speed!
You are a genuine gem Dr patrick, you constantly keep bringing to light information that would otherwise take us 'the masses that care' year to stumble across... Genuinely keep up the good work, this info is making people's lives better. lol! if they're smart enough to listen and then try for themselves.
Thanks fo this webinar. I have learnt so much from it. Interestingly i eat muringo but i never knew that it's such a wonderful plant. I will encourage my family from back home in Kenya to eat more of it because it's a very common plant there. As concerning Brocolli sprout i have started growing my own. Thank to Rhonda and her video on Sulforaphane. Cheers
I believe it is Brassica Protection Products that makes the SGS for Dr. Fahey's Hopkins research. www.prweb.com/releases/Brassica/JHU/prweb12261501.htm At the bottom of the article they list the nutraceutical companies that they sell their patented SGS: Xymogen and Thorne are amongst them. At Amazon Jarrow's BroccoMax -- despite not having the patented SGS -- looks more popular than Thorne's Crucera SGS. And it has myrosinase: "BroccoMax® uses a patented process that presesrves myrosinase, the enzyme in broccoli that metabolizes SGS (Sulforaphane Glucosinolate, a.k.a. glucoraphanin) in the small intestine into sulforaphane." If not doing sprouts my inclination would be to go with the patented SGS of Thorne or Xymogen,, altho Jarrow's BroccoMax is a lot cheaper. Dr. Patrick, any guidance here?
I buy organic Moringa powder and put a teaspoon on my food once in a while. I also use organic Astragalus powder in my coffee 2 or 3 times a day along with Reishi mushroom powder. I also eat Fo-Ti root powder with Chaga mushroom once a day I mix it with avocado or peanut butter. I work out 3 times a week and i am 61 years old and feel like I am 30 I could say honestly that i feel like i am getting younger and i see my grey hair turning back to it's original color and wrinkles are diminishing. I also don't have a gallbladder so my stomach bile is limited.
Raw nuts and seeds often have enzyme inhibitors on the outside which is only removed by soaking and rinsing at which point you are on the road to sprouting having germinated the seed.
Mustard seeds sprout like Broccoli seeds, or at about the same rate. I'm tossing them in together in the same sprouting Jar to sprout. The mustard seeds are light yellow that stand out against the black Broccoli seeds so that you can see if the mustard seeds are viable and therefore have active myrosinase (unbaked).
"Boiling broccoli prevents the formation of any significant levels of sulforaphane due to inactivation of the enzyme myrosinase. However, researchers from the University of Reading found that the addition of powdered mustard seeds to the heat processed broccoli significantly increased the formation of sulforaphane.Feb 9, 2016"?
Well done, yet another great interview on Sulforaphane! here in Thailand, moringa is the "tree of life." I have 9 in my garden. I make my own oil and seed content capslues, which are very effective combined with serrapeptase. I have a nasal spray charged with NO as a blood thinners and blood clot buster it dissolves the clot chains, kicking backsides to walk 3+km a day
Thank you! I was making a presentation on sulforaphane, NRF2 and a paper about it relieving doxorubicin induced heart attacks. This video was a great help as some of the papers I cited were by Dr. Fahey
I make an organic broccoli salad with organic raisins, organic sunflower seeds, organic red onion and bacon..... The dressing is organic mayo, ACV and a little stevia..... I make a big bowl weekly.... SUPER FOOD 🥦
One of the biggest problems with the food service industry is we treat eating as entertainment rather than nutrition. Also food suppression is real. Most people are not growing edibles in their yards.
Absolutely fantastic! Mesmerised for the entire talk. One question! Given that turnips and radishes are the same Family as broccoli, does that mean that myrosinase and sulforaphane are present in both? Or are they stacked up in the different members of the family in different concentrations? Eg turnips and radishes max on myrosinase while others like broccoli are stacked with sulforaphane?
So i ground a teaspoon of seeds in a spice grinder and mixed the powder with an ounce of peanut butter. tasted good, sort of like crunchy PB. will i now live to be 100? Is this all i have to do? next time i'll wait 10 minutes before eating for the sulforaphane to get stronger. Thanks for the info!
Wow! From this I took that I can grind broccoli and mustard seeds (about a tablespoon each) put it in my smoothies and sprinkle fresh ground seeds on my cooling cooked foods. I’m interested in any further studies on the effects of the seeds on cell activity. Any hints? Thank you for your well thought out information! It’s so refreshing and enheartening for me personally to see professionals disbursing this information freely. It’s helping me to change my attitude to everyone with a ‘Dr.’ before their name!
Dr Patrick, so i can grind broccoli seeds and add them to my smoothies and i would be getting the most out of them and i don't have to grow the sprouts ?
Dr. Patrick! How was your broccoli seed smoothie? Did you blend them with other fruits or veggies? Are there fruits or veggies that might deactivate the sulforaphane or stop the enzymatic reactions e we want?
Great interview, very interesting topic, thank you so much! So what is the conclusion to get the best effect? Eat ground broccoli seeds directly, or eat the sprouts? Does is make a difference to eat the sprouts or to drink them blended up in a smoothie?
Tobias Bader im not sure of the blending thing but in my own opinion, id go with the broccoli sprouts. just because the broccoli seed thing seems to have no studies that i know of.. but broccoli sprouts is a conclusive "yes" it is safe and good for you just dont go over board
Here's an easy way to quickly and easily spot a particular word or mention in a CZcams video (especially useful when the video is lengthy). Click on the three dots next to the SAVE button under a video to open it's transcript on the top right side of the video. Place the cursor at the beginning of the transcript. Now press Ctrl+F on your keyboard to open the Find Search field and type in the word you want to locate into it. You'll see that your cursor will automatically go to the first occurance of the word. You may use the up and down arrow keys next to the Find Search field to locate more instances of the word above or below the current one. Once located, just click on the line that contains your word to be taken directly to the replay of the exact conversation in the video. If it doesn't play just click the play button. Have fun!
It would be nice to have a supplement that includes Broccoli sprouts, Broccoli seeds, Moringa, Wasabi and Mustard greens to enhance its cumulative effects.
Wonder if it could help cancer victims now. I watched someone growing sprout 🌱 order organic seeds untreated. Watching this I am going to chew tablespoon each morning. Tested a pinch to see if any reaction first. I am Carnivore but think this seeds mine say Broccoli Sprouting organic no pesticides use.
Dr. Fahey is incorrect. I put broccoli seeds in my coffer grinder and the powder actually has a pleasant nutty flavor - not particularly bitter to my taste at all. Can easily see sprinkling on my oatmeal in the morning or smoothy. Sprouting is a pain.
I has an idea along these lines too. The correct probiotic bacteria in fermentation might take care of all of the precursor work. The question would be is there a cheap, simple test for sulforaphane that would allow for experimentation with different fermentation batches.
Can you activate the legend option in your videos? I'm from brazil and some times is difficult for me understand complicated names of hormones or substances. Love your channel! Thanks
Thank you Rhonda and Jed for your amazing and very important work! I wonder if lacto fermenting the seeds/sprouts will convert glucoraphanin to a shelf stable form and ready to eat sulforaphane.. maybe even more bio available, but maybe instead of lacto fermenting a specific species of bacteria starter should be used, a Myrosinase producing bacteria which would pre-digest for people that don't have enough. Also, the fermenting environment should have this main bacteria and other harmful ones hopefully don't survive, like e.coli from unclean sprouting I would love to hear Rhonda's thoughts on this Edit: I just saw on Mercola's website fermented broccoli sprouts, They write "...And because we use fermented broccoli sprouts, the conversion to sulforaphane happens before you even take it!..." I wish I could find more information on this And this patent: patents.google.com/patent/US20160279090
I love the way she just listens, she doesn't keep interrupting him trying to show off her own intelligence like so many interviewers do. Awesome information.
It is exactly what I thought while listening) Dr. Rhonda is a skillful interviewer
COMPLETELY agree!
It's because she doesn't know anything.
Ha ha. Gotcha. As you said, she's a great interviewer and much better than a few other "scientist" podcasters. I can say who, but ppl will think I'm a "hater", so I won't, even though it's just a genuinely honest experience/observation.
Seriously, thank you so much Dr. Patrick. After listening to your podcast I’ve lost 45 pounds. My life is filled with energy and I feel like I have a new lease on life. You are such an inspiration and we are all lucky to have you as a resource. Thank you so much again and I’ll never give up my broccoli sprouts!
What is that podcast called please
How donit loose ?
I have fatty liver .. pls share what diet you did and did you worknout
I live in Southern California in an off the grid community, I've been growing broccoli sprouts from fall to spring, it's too hot in the summer. I also have a moringa tree, every part of the tree is edible. My goal is to create a food oasis through permaculture. Funny, I do dehydrate a variety of lettuce, spinach, kale, green beans, okra, blueberries, raspberries, strawberries, pomegranate, cherries, mango....also I have a desert peach tree, fig tree, a palm date, a Palo Verde tree, 2 mesquite trees, an orange tree, a lime tree and an apple tree. I can easily dehydrate all of this and I make jerky from the chickens and turkeys I raise. I feed them wheat grass sprouts among other sprouts and forage like purse lane. I mostly stick to a keto diet, I've reversed diabetes and lost 75 pounds. I feel younger at 46 than I felt at 26.😁 Learning about the science of nutrition is like my religion. ❤
Wow so awesome
Thanks for allowing your guests to give long and detailed answers. This way one gets to the logic behind their answers
Oh Lord, my God,
When I in awesome wonder
Consider all the Life Thy Hands have made.
I study the cell.
I graph the complex pathways.
Thy wisdom throughout the human body displayed.
Then sings my soul,
My Savior God to Thee,
How great Thou art.
How great Thou art.
Then sings my soul,
My Savior God to Thee,
How great Thou art.
How great Thou art.
I personally sit in silent awe
every time I listen to these chemists, biologists, MDs, and researchers on CZcams. First in awe of their knowledge, of course. But then at the incredible complexity of the physical system we still are so far away from understanding.
But I believe one day we will grasp its full complexity, as God intends we should.
Rhonda has an incredible ability to slice through all the jargon and layers and find out how something can benefit the health of people. I am thankful to have someone like this to give us this valuable information.
I watched a lot of videos with Rhonda Patrick. She is so remarkable to listening the people like here to Dr. Jed Fahey or Dr. Bruce Ames, as if she is in a constant flow like once Mihaly Csikszentmihalyi described. One can feel that she has a fulfilled professional life and is very happy being in that environment. My congratulations to her and all the successful videos she posted..And many thanks.
In this 2-hour and 30 minute interview, we discuss...
• 00:00:00 - the early history of sulforaphane research, including key initial discoveries.
• 00:00:37 - the serendipitous unfolding of events that lead to the converging of the research on the NRF2 stress response pathway with the sulforaphane-related research going on at the same institute Johns Hopkins.
• 00:05:06 - why cruciferous vegetables bother to create isothiocyanates in the first place.
• 00:07:26 - the involvement of the heat shock proteins, in addition to the increased activity of Nrf2, as an additional cellular response mechanism that's been observed in association with sulforaphane.
• 00:08:11 - how sulforaphane affects a diverse array of biochemical processes from glutathione synthesis to elimination of reactive oxygen species and detoxification of harmful compounds, including carcinogens.
• 00:15:01 - whether or not to cook your cruciferous vegetables.
• 00:15:34 - the epidemiological (associative) evidence that cruciferous vegetable consumption may help reduce the risk of cancer.
• 00:18:30 - the extremely unpredictable nature of endogenous conversion of glucoraphanin (the precursor) into sulforaphane between person to person.
• 00:22:14 - practical information surrounding supplementation of sulforaphane.
• 00:27:05 - the effect one particular french sulforaphane supplement had on the doubling rate of PSA, which is a marker for prostate cancer recurrence in prostate cancer patients.
• 00:28:17 - the role that the Cullman Chemoprotection Center at Johns Hopkins has played, in addition to fundamental research, in providing early, vital infrastructure enabling some of the efforts of the international research community in elucidating the effects of sulforaphane and related compounds and the underlying biological pathways.
• 00:28:26 - the incredible, almost geometric growth in new studies that has occurred since the advent of a few of the key discoveries about sulforaphane and its method of action.
• 00:32:48 - the practicality of probiotics as a way to improve endogenous myrosinase activity needed to convert the precursor to sulforaphane into the bioactive sulforaphane.
• 00:33:26 - the involvement of our gut bacteria in our ability to convert the precursor of sulforaphane into its active form.
• 00:37:13 - whether or not endogenous myrosinase activity improves as a function of repeated challenge with glucoraphanin (the precursor to sulforaphane).
• 00:39:30 - why probiotics may vary in their degree of efficacy.
• 00:43:00 - why consuming isothiocyanates to reduce the number of bacterial colonies of h. pylori, a risk factor for peptic ulcers and stomach cancer, may turn out to be a better intervention than complete eradication of the species with antibiotics.
• 00:47:21 - the bizarre relationship h. pylori has with childhood asthma, where it has been shown that having some h. pylori seems to reduce asthma incidence in childhood.
• 00:52:28 - the effect sulforaphane has on inflammation and why inflammation is often a great therapeutic target for many different diseases, including diseases of aging.
• 00:54:05 - the life extension properties broccoli has been shown to have in an insect model of aging.
• 00:59:27 - the underlying causes of Hutchinson-Gilford progeria and the promise sulforaphane may hold for this disease of rapid aging.
• 01:09:00 - the effects of sulforaphane or Nrf2 activation on diseases of the brain, such as autism (human evidence) and Alzheimer's (animal evidence), possibly through anti-oxidative or anti-inflammatory effects.
• 01:11:09 - the so-called autistic fever response whereby autistic patients report a sudden reversal of symptoms during brief periods of fever.
• 01:10:05 - the role heat shock proteins might play more broadly in the prevention of certain neurological diseases.
• 01:19:00 - the challenges inherent in clinical trials where scientists may be extremely optimistic about the effects that might be observed, but still have to exercise caution and choose trial conditions that may be conservative, for the good of the people whose lives and hopes hang in the balance.
• 01:27:01 - the role of inflammation and depression and what some studies on animals have demonstrated in terms of sulforaphane's potential as an antidepressant.
• 01:42:30 - a special isothiocyanate-containing plant known as Moringa or sometimes referred to as the drumstick tree or the horseradish tree.
• 01:46:32 - Dr. Fahey's inadvertent foray into the consumption of exotic meats during a visit to Africa.
• 01:51:15 - a compound commonly associated with broccoli: indole-3-carbinol and its downstream product diindolylmethane (DIIM).
• 01:57:00 - the practicality of using mustard seed powder as an extra source of myrosinase, possibly for your cooked cruciferous vegetables.
• 02:00:13 - whether or not it makes sense to freeze broccoli sprouts in order to extend their shelf life, and possibly even increase sulforaphane within certain contexts.
• 02:05:25 - Dr. Fahey's thoughts on where endogenous conversion of glucoraphanin occurs in the body, as well as how long it takes before sulforaphane metabolites hit the bloodstream after ingestion.
• 02:07:25 - Some general thoughts on frequency in terms of how often one might need to take sulforaphane to elicit its biological effects.
• 02:12:16 - why sulforaphane may one day be a component of sunscreen.
• 02:12:31 - what some of the upcoming trials involving sulforaphane are at the Cullman Chemoprotection Center.
• 02:17:07 - the incredible way in which a sulforaphane-rich broccoli sprout beverage was shown to dramatically enhance the detoxification of benzene through excretion: one study showed up to 61% starting immediately after supplementation.
Those are some big ideas.
Thank you for the time stamps! Much appreciated.
Merci
FoundMyFitness thank you for the time stamps.
bob dylan only if you chew. + heat, I'm gonna put it in my coffee
Your sulforaphane videos have turned me into a health geek. I'm blown away by this info! Even bought broccoli sprouting kits for my friends and family and forced them to watch some of your videos.
Lol.. Just did the same thing this morning... Well done!
Where you buy in Canada..does it need to be organic ..can you buy in powder😊
I have issues pcos insulin resistance and fatty liver
I just want a girl that looks at me the same way Dr. Rhonda Patrick looks at cruciferous vegetables. : P
saferseas me too
Maxineyoung1
Lmao!
🤣🤣🤣🤣
Ha ha ha 😂, that would extend our lifespan more than eating cruciferous vegetables.
I've been doing my own trial for almost a year with broccoli sprout capsules twice a day while undergoing chemotherapy once a week and can report that my stage IV lung cancer has currently been arrested so far. I'm not sure if it's the broccoli or the chemo but I'll keep on doing both till I find something better or cancer continues to grow again.Thanks, Doc, I'm watching you and trying to learn and understand all those big words you say so I can later look them up and try to save my own life.
How are you doing now?
Are you alive SANDMAN? Please respond, If you have died, then do not trouble yourself with replying it's alright.
How you doing
I am sooo encouraged by your commitment to researching autism, schizophrenia, and bipolar diseases, allof which have affected my family!!
Pls share are things improved and how
Loved all the helpful information but particularly the part on Moringa that started at 13:15 and then again at 1:33:58! As a holistic nutritionist I completely loved the material on gut microbiome as well!
I am very interested in this, since I've had 2 surgeries for bladder cancer (8.5 yrs ago). At 63 now, I want to stay healthy (who doesn't??). I'm also treating my gut biome with fermented milk which has really helped. I was on antibiotics for 14 yrs for rosacea; my dermatologist finally found a topical med that works great. I've grown sprouts before, so will probably add the brocc sprouts to my salads and smoothies.
Brenda Wollenberg Moringa is also called horseradish tree. The peeled root is very pungent, but has proven to be unhealthy if too much of the grated root is eaten or eaten too often.
Please be careful with moringa
@@KellyDaAngel Could you elaborate a bit ? That was brief.
@@pearlas6943 Yes. I went to purchase moringa on Amazon. Upon reading the reviews, each brand has many reviews that are people saying they got violently ill. Including a brand the expert mentioned in another video.
What a genuinely nice and knowledgeable man!? The interview is so long and it just keeps striking me how he is so pleasant and so careful in laying out his arguments and sharing his immense knowledge! He has a great voice too. :-)
Dr Jed is amazing, so easy to understand and listen to. thank you for all your hard work and bringing us all these great interviews .
supernova1976 dammit!! Lol
This is fantastic. Knowledge from the source. Not filtered by journalists that don’t understand and get it wrong. Knowledge is power.
WOW!!! I will have earned a PHD in Sulforaphane after watching this several times, LOL. A wealth of info. THANKS!!!
Do you have mustard powder?
Not get some broccoli lol
Thanks for another incredibly informative and deeply interesting interview. This was the best I've seen (and you've done many that are truly great). Dr Fahey is a wonderful person - thoughtful, sensitive, poised...and has impressive and vast knowledge. You too are a wonderful woman Rhonda. Thanks for sharing your work. You are doing a great service to the many people dedicated to enriching their lives - although I must say, at least in my case, distracting me from the work I should be doing. Your interviews are too damn interesting not to watch.
Thank you! Dr. Fahey was an amazing guest. I'm very pleased he took the time to come on.
Dr. Greger talks about ways to cook broccoli after chopping it so that the conversion to Sulfuraphane happens before cooking it. Or eating a little raw with your cooked to maintain the enzymes needed for conversion
I never watch a 2 hr video on CZcams but this was well worth time spent. Thank you both for this valuable insight. Please do more videos on broccoli sprout SEEDS.
What a great interview and what a nice guy, really down-to-earth and dedicated to his work with the ultimate purpose of doing good for people. Thanks Rhonda for what you’re doing, now back to eating those sprouts.
What an amazing doctoral researcher. This is true and powerful, healing information for everyone.
54:20 - Rhonda: "Have you seen this study?"
Jed: "No"
Rhonda: "OK, so let me tel l you"
She is sooooo happy!
I’m happy that’s she’s so happy 😁
Awesome interview. I was particularly struck by Dr. Fahey’s apparently high level of self-awareness and communication skills (e.g. he communicates very efficiently with little filler words and provides helpful sentence cues about where he intends to move the conversation).
I'm 53 and have eaten a lot of sugar over the years and about 30 pounds overweight and as a programmer use my brain non-stop all week. So over years the brain fog has built up and just a couple weeks into getting lots of sulforaphane I can tell a huge difference in brain clarity. This substance may not help a young person much but if you are older I would sure recommend it!
Thanks Dr. Patrick, and I have been working on sulfur deficiencies after viewing Dr. Seneff's work, along with yours. Would never meet these Dr.s of Science if it was not for you ...Big fan ..Also, the equatorial and tropical diet, in fact does have fruits available year around, but nothing like the "Sweet - Less Bitter" we have hybridized. 70 Going On 10
Apparently the broccoli seeds contain an anti-metabolite: erucic acid, which inhibits the absorption of the glucoraphanin. Therefore it's not a good idea to consume the seeds directly. The acid is broken down during the sprouting process.
Oh thank you for this!
Wondering if simply soaking the seeds for a few hours will help with the acid dissipation?
i dont think its true. erucic is not inhibitor, but it is just "proven" to cause heart problems in mice, and was never proven to damage humans in anything
Thanks, I just ground up a tablespoon in a coffee bean grinder, oh man feeling a burn in the esophagus, back to sprouting for me.
@@kevindecoteau3186 no, it kills sulphoraphane
In philippines, we cook Moringa in chicken soup or with monggo (moong soup). It is the only vegetable i eat when i was young.
It's cool how now everyone can speculate together and comment and share to grasp these overly complicated systems into manageable and hopefully useful ways. Thats crazy about the fever study. I just assumed "fevers" were a reaction to pesticide on processed and store bought food but to truely understand how all these compounds interact and commune is really cool. I normally don't like scientist and doctors but I like these two curious and smart people. They are sticking their necks out even making these videos
Rhonda I love your videos. Please don't ever stop. I love how much effort you put into them, from the definitions of terms to the time links to specific topics discussed. Yes yes yes
Dr Fahey is a very compassionate man. That's my impression from listening to him here, talk about people's suffering.
I love these videos! Unfortunately I will have to watch them a couple times with notebook in hand. 2+ hours well spent. :)
Fascinating interview! The footnotes and graphs are INCREDIBLY helpful! Thank you so much for all the hard word making these videos. I subscribed!
Thank you so much - extremely informative and has reignited my interest in moringa products - and of course the various pathways involved with broccoli sprouting and the goodness thereof - it is amazing to me why I and others have not taken to growing broccoli sprouts every day since there is now such a wealth of information as to how healthy it is for us - (and for such a modest output) - thanks to you and Dr. Jed Fahey who make it so understandable and interesting!
Thank you for the work that you do in editing these videos. The time stamps for the topics are nice but I imagine you did that as a way to maximize your own understanding of the information shared with you during this very rare encounter ;). Also, overlaying the commentary with the relevant data really puts into context what he's bringing up and helps in grasping what he's discussing. It helps too, that he talks in a very understandable manner.
I love a scientist who will say "we don't know". I have noticed a huge difference personally in the past couple weeks from sulforaphane.
Great webinar Dr. Patrick and Dr. Fahey, we need more people like you ! I love details, Dr. P asked awesome questions I would have asked. I’ve been sharing your podcasts
Thank you for the simplified explanations and extra info at the bottom of the screen Rhonda! Awesome interview. Thank you Jed & Rhonda! Keep fighting the good fight :)
Great interview. Dr. Fahey was VERY informative. Love your work, Rhonda.
Thanks Rhonda dear for your wonderful podcast ! It has opened my eyes and Horizon on the multiple Health Benefits of the Mooring which I planted in my backyard & consuming fresh Broccoli Smoothies !👍🌈David🌈
You're the best Rhonda. Keep doing what you do.
I have a supergreens suppliment of kale, moringa, and wheat grass, I get high when I consume some. I kid you not, the feeling is almost instantaneous, light headed and feeling happy.
Is it heavy metal free? Organic gmo?
supposed to be organic, I am sprouting my own brocoli seeds now
i Feel guilty for eating 2 slices on pizza and chicken wings while watching this
lol
😂
.We live in a free country, one can die is ignorant as s/he wants to
Put a bunch of micro greens on the pizza, crush a spoonful of fresh mustard seeds into the ranch you dip your chicken wings. Profit. XD
Ice cream filled by PBJ lol
Followed by
Thank CZcams! I can’t imagine having to listen to all of these scientists, professors, and doctors on 1X speed!
Always at least 1.5X, but if possible, 2X speed!
You are a genuine gem Dr patrick, you constantly keep bringing to light information that would otherwise take us 'the masses that care' year to stumble across... Genuinely keep up the good work, this info is making people's lives better. lol! if they're smart enough to listen and then try for themselves.
Thanks fo this webinar. I have learnt so much from it. Interestingly i eat muringo but i never knew that it's such a wonderful plant.
I will encourage my family from back home in Kenya to eat more of it because it's a very common plant there.
As concerning Brocolli sprout i have started growing my own. Thank to Rhonda and her video on Sulforaphane. Cheers
I believe it is Brassica Protection Products that makes the SGS for Dr. Fahey's Hopkins research. www.prweb.com/releases/Brassica/JHU/prweb12261501.htm
At the bottom of the article they list the nutraceutical companies that they sell their patented SGS: Xymogen and Thorne are amongst them.
At Amazon Jarrow's BroccoMax -- despite not having the patented SGS -- looks more popular than Thorne's Crucera SGS. And it has myrosinase: "BroccoMax® uses a patented process that presesrves myrosinase, the enzyme in broccoli that metabolizes SGS (Sulforaphane Glucosinolate, a.k.a. glucoraphanin) in the small intestine into sulforaphane."
If not doing sprouts my inclination would be to go with the patented SGS of Thorne or Xymogen,, altho Jarrow's BroccoMax is a lot cheaper. Dr. Patrick, any guidance here?
Watching this while drinking my moringa tea - who knew...
Far, one of the best dialogues showing all the life behind this topic
I buy organic Moringa powder and put a teaspoon on my food once in a while. I also use organic Astragalus powder in my coffee 2 or 3 times a day along with Reishi mushroom powder. I also eat Fo-Ti root powder with Chaga mushroom once a day I mix it with avocado or peanut butter. I work out 3 times a week and i am 61 years old and feel like I am 30 I could say honestly that i feel like i am getting younger and i see my grey hair turning back to it's original color and wrinkles are diminishing. I also don't have a gallbladder so my stomach bile is limited.
How does moringa taste?
@@TillyFloss Don't taste to bad Leafy but with a little sweetness
Anyone else here for Dr Rhonda’s voice? I could listen to her talk all day😍
Thank you Rhonda . Excellent interviewing abilities . Cheers from Pat nz
AUTISM IS NOT A DISEASE.
Raw nuts and seeds often have enzyme inhibitors on the outside which is only removed by soaking and rinsing at which point you are on the road to sprouting having germinated the seed.
Mustard seeds sprout like Broccoli seeds, or at about the same rate. I'm tossing them in together in the same sprouting Jar to sprout. The mustard seeds are light yellow that stand out against the black Broccoli seeds so that you can see if the mustard seeds are viable and therefore have active myrosinase (unbaked).
"Boiling broccoli prevents the formation of any significant levels of sulforaphane due to inactivation of the enzyme myrosinase. However, researchers from the University of Reading found that the addition of powdered mustard seeds to the heat processed broccoli significantly increased the formation of sulforaphane.Feb 9, 2016"?
Adding broccoli seeds to my vacuum blended smoothie sound like a great idea :)
Definitely one of more interesting people you've interviewed. Please find more people like this. Excellent!! *****
Well done, yet another great interview on Sulforaphane! here in Thailand, moringa is the "tree of life." I have 9 in my garden. I make my own oil and seed content capslues, which are very effective combined with serrapeptase. I have a nasal spray charged with NO as a blood thinners and blood clot buster it dissolves the clot chains, kicking backsides to walk 3+km a day
Truly enjoyed! I stayed intrigued for the entire episode. Very informative. Thanks!
Marvelous. The interview was great too.
120:44. Studies use Avmacol for their SFN because its got 35% bioavailabilty and its consistent.
eat real food , grow sprouts .It takes ONLY 4 days
learned a lot and hoping to be an instrument of change in allowing this knowledge to be shared to people who need to hear this.
I'm not sure I'm smart enough to be watching this, but even though 90% of this is going over my head, Iam stilll finding it interesting.
Outstanding video once again, tell Dr. Ames we'd like to hear from him again.
Thank you! I was making a presentation on sulforaphane, NRF2 and a paper about it relieving doxorubicin induced heart attacks. This video was a great help as some of the papers I cited were by Dr. Fahey
I make an organic broccoli salad with organic raisins, organic sunflower seeds, organic red onion and bacon..... The dressing is organic mayo, ACV and a little stevia..... I make a big bowl weekly.... SUPER FOOD 🥦
AWESOME video. I liked how the mechanisms and pathways were thoroughly explained and related back to one another.
Thank you for this wonderful video. I know I will watch it many times to assimilate all the information.
One of the biggest problems with the food service industry is we treat eating as entertainment rather than nutrition. Also food suppression is real. Most people are not growing edibles in their yards.
Absolutely fantastic! Mesmerised for the entire talk. One question! Given that turnips and radishes are the same Family as broccoli, does that mean that myrosinase and sulforaphane are present in both? Or are they stacked up in the different members of the family in different concentrations? Eg turnips and radishes max on myrosinase while others like broccoli are stacked with sulforaphane?
So i ground a teaspoon of seeds in a spice grinder and mixed the powder with an ounce of peanut butter. tasted good, sort of like crunchy PB. will i now live to be 100? Is this all i have to do? next time i'll wait 10 minutes before eating for the sulforaphane to get stronger. Thanks for the info!
Wow! From this I took that I can grind broccoli and mustard seeds (about a tablespoon each) put it in my smoothies and sprinkle fresh ground seeds on my cooling cooked foods.
I’m interested in any further studies on the effects of the seeds on cell activity. Any hints?
Thank you for your well thought out information! It’s so refreshing and enheartening for me personally to see professionals disbursing this information freely. It’s helping me to change my attitude to everyone with a ‘Dr.’ before their name!
Thanks so much for this treasure of a video!
To patreon your efforts is something I value every time more and more!
Cheers from Italy, dr Rhonda!
Dr
Patrick, so i can grind broccoli seeds and add them to my smoothies and i would be getting the most
out of them and i don't have to grow the sprouts ?
Wonderful news! Great interview! Fantastic people!
hes doing an amazing job at not making eye contact with her boobs. A man of pure genius. im sorry but Dr Rhonda Patrick is an A++++
Dr. Patrick! How was your broccoli seed smoothie?
Did you blend them with other fruits or veggies? Are there fruits or veggies that might deactivate the sulforaphane or stop the enzymatic reactions e we want?
Well paced for my enjoyment... good team!
Absolutely fascinating....I'm sold on sulforaphane...
I did not intend to watch this whole video. Somehow it held my interest the whole way through!
Same here
Breasts can do that
Tattas!!!
@@swisstrader lol. I was going to write the same thing.
Can we hang up the broccoli sprouts to dry and them powder them up into pills?
Dr. Rhonda, broccoli stems are sweet and crunchy and easy to eat raw if peeled. Do they contain the active enzyme?
I appreciate any answer, Thanks.
Reading the comments. She simply is an unusually attractive woman, body, mind and probably soul. Great interviewer.
Glad your videos/podcast is back!
Thank you Dr Rhonda for this amazing podcast..keep going...ربي يحفظك اميييين🙏
Great interview, very interesting topic, thank you so much!
So what is the conclusion to get the best effect? Eat ground broccoli seeds directly, or eat the sprouts? Does is make a difference to eat the sprouts or to drink them blended up in a smoothie?
Tobias Bader im not sure of the blending thing but in my own opinion, id go with the broccoli sprouts. just because the broccoli seed thing seems to have no studies that i know of.. but broccoli sprouts is a conclusive "yes" it is safe and good for you just dont go over board
christopher laffy thanks for your thoughts! :)
Here's an easy way to quickly and easily spot a particular word or mention in a CZcams video (especially useful when the video is lengthy). Click on the three dots next to the SAVE button under a video to open it's transcript on the top right side of the video. Place the cursor at the beginning of the transcript. Now press Ctrl+F on your keyboard to open the Find Search field and type in the word you want to locate into it. You'll see that your cursor will automatically go to the first occurance of the word. You may use the up and down arrow keys next to the Find Search field to locate more instances of the word above or below the current one. Once located, just click on the line that contains your word to be taken directly to the replay of the exact conversation in the video. If it doesn't play just click the play button. Have fun!
There are quite a few animal or in vitro studies on Sulforaphane but still i am reluctant to be a advocate because human trials are stil scarce.
It would be nice to have a supplement that includes Broccoli sprouts, Broccoli seeds, Moringa, Wasabi and Mustard greens to enhance its cumulative effects.
What a great guy
Wonder if it could help cancer victims now. I watched someone growing sprout 🌱 order organic seeds untreated. Watching this I am going to chew tablespoon each morning. Tested a pinch to see if any reaction first. I am Carnivore but think this seeds mine say Broccoli Sprouting organic no pesticides use.
Dr. Fahey is incorrect. I put broccoli seeds in my coffer grinder and the powder actually has a pleasant nutty flavor - not particularly bitter to my taste at all. Can easily see sprinkling on my oatmeal in the morning or smoothy. Sprouting is a pain.
Thank you Dr Rhonda Patrick excellent knowledge and interesting facts!
Thanks for the footnotes!! 👌
Turmeric is more bio-available when fermented. I wonder if this is also true with broccoli sprouts?
I also wondered about fermenting - the sprouts and the seeds. Will try myself both using honey and salt brine
I has an idea along these lines too. The correct probiotic bacteria in fermentation might take care of all of the precursor work. The question would be is there a cheap, simple test for sulforaphane that would allow for experimentation with different fermentation batches.
Look up Meriva sf. 30x more absorption if curcumin
Add black pepper to ramp up turmeric
Can you activate the legend option in your videos? I'm from brazil and some times is difficult for me understand complicated names of hormones or substances. Love your channel! Thanks
Hi, Lais! I turned it on and it will be on by default from now on.
Thank you! :)
My new go to snack? Raw broccoli with sprout powder in a whole mustard seed, mustard sauce. Super legit
Finally a new Video! :) Love em.
Btw you look great.
Thank you Rhonda and Jed for your amazing and very important work!
I wonder if lacto fermenting the seeds/sprouts will convert glucoraphanin to a shelf stable form and ready to eat sulforaphane.. maybe even more bio available,
but maybe instead of lacto fermenting a specific species of bacteria starter should be used, a Myrosinase producing bacteria which would pre-digest for people that don't have enough.
Also, the fermenting environment should have this main bacteria and other harmful ones hopefully don't survive, like e.coli from unclean sprouting
I would love to hear Rhonda's thoughts on this
Edit:
I just saw on Mercola's website fermented broccoli sprouts,
They write "...And because we use fermented broccoli sprouts, the conversion to sulforaphane happens before you even take it!..." I wish I could find more information on this
And this patent: patents.google.com/patent/US20160279090