What all dieters need to know about Ozempic
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- čas přidán 12. 07. 2024
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Chapters:
00:00 Intro
00:18 Miracle weight-loss drugs
00:49 How these drugs work?
02:26 Industry response
03:01 Problem 1: Exacerbating nutritional deficiencies
03:45 Problem 2: Muscle loss
04:48 Problem 3: These drugs are expensive
05:02 Problem 4: Side-effects
05:57 Problem 5: Regaining the lost weight
06:53 Similarity to anabolic steroids
08:01 Conclusion
Reference:
pubmed.ncbi.nlm.nih.gov/38029...
www.frontiersin.org/journals/...
www.bmj.com/content/384/bmj-2...
#ozempic #wegovy #rybelsus #semaglutide #weightlossdrugs #nutrition #weightloss #steroids #dieting #healthwarnings #mennohenselmans #personaltrainer #personaltrainers #personaltraining #personaltrainerlife #personaltraineronline - Věda a technologie
Addendum: if this video sounds overly negative, note that there is direct research showing that weight loss aids reduce self-efficacy during dieting. Basically, weight loss supplements make people focus more on the drugs and less on their diet. The people most drawn to these types of drugs are the least likely to make sustainable lifestyle changes in the process, in my coaching experience.
www.ncbi.nlm.nih.gov/pmc/articles/PMC4182347/
Bless you
Pin your comment so people can see it
Edit: yasss
I’m just going to keep eating well and building muscle knowing that my body will gradually fix itself as I maintain this healthy balance over the course of my life. Letting go of the idea of short term results has made my whole journey so much more productive, along with the massively peaceful inner certainty that I will get where I want without needing to focus on it all so darn much.
I don't know, I lost 225lbs naturally without drugs or surgery and there's something weird that happens when you get to a lower weight, I honest to god believed in my heart of hearts that my diet was sustainable, ample of amount of calories, balanced macros, junk food in moderation, I even worked with a RD to make sure my diet was as sustainable and healthy as it could be- until the "food noise", fatigue, and night eating started happening. It's crazy to think that I had willpower and discipline at 400lbs and now I don't at 180lbs. Ozempic would be a lifesaver for those of us who put in the effort but are at the mercy of a physiological backlash from a body that has adapted to obesity.
@@LN-lr4rg Sounds like a cop-out tbh.
Messege understood; taking ozempic and steroids for the rest of my life! Jacked and shredded!
I'm happy I am not the only 1 who understood that this is the real solution.
The Ozempic will not help with that lol. Steroids, hell yes. Way ahead of you, bud. Stick with GH instead of the Ozempic. Pun intended.
That life will be super short. Congrats.
Bro, there's few people like us who take in and process information then use it to apply it to themselfs as effectively as possible.
You also need a ton of sleep to grow, may I suggest xanax?
Uhhh.. the rest of your life...? When you use this medicine and steroides without medicale indication your life expectany will be 3 to 5 years in poor health.. at most!
Ozempic will probably be a game changer 1 or 2 decades from now, and I'm happy for people who will be able to benefit from it. Now, if only we could get a drug that makes people "obsessed" with working out, sleep, and have a balanced diet 😮💨
No, I'd rather have more people lazy and unmotivated to work out. It makes me look better in comparison; since other people's health (strangers) is not my concern.
@@SteveJonesOwnsDSPit’s your concern because you subsidize their obesity through your insurance costs and taxes. Something like a third of healthcare costs go to type 2 diabetes related conditions.
@@SteveJonesOwnsDSPwe literally are all in it together. We should want good for all
I'll be real. I'm on Ozempic and it did more for me than just make me less hungry. It started a kind of upward spiral where I started strength training again to avoid muscle loss, so I lost weight and maintained muscle. It felt so great that I started to really get into fitness again after several years of struggling. It has changed my relationship with food and that has created a cascade of other positive changes. I'm not obsessed with food or bingeing, which makes all the other stuff so much easier. Still not easy, but finally more doable and exciting.
@ flabio7074 Yeah man. That actually makes me so angry as someone who lives in the US.
Ozempic = not natty: Confirmed.
In all seriousness, good and fair video. I'm 'lucky' in that I don't have severe issues with hunger on a diet but it is a gamechanger for those that do. I think Ozempic for fat loss + some maintenance could make transitioning into healthier body weights easier with strong hunger signaling is a great path. Problem is that most people will likely let the pill do the work, still eat 'intuitively' and they will need to stay on for life to keep the benefits.
The vast majority of obese people could easily lose weight without any drugs if they actually wanted to. Problem is they don't. They prefer being lazy in terms of unhealthy food choices, unhealthy habits and exercise.
It’s an injection, not a pill
Wait till the side effects and lawsuits pile up. Also, it’s not a pill. JFC.
I think some physician expert on hunger said that they've learnt from studying ozempic that even after quitting, they kept the weight off after months so it's promising
Thank you for taking the moment to share this video. Very relevant and answered both of mine and my wife’s questions about GLP-1. Thank you and have an awesome day brother!
What bothers me the most is the having low overall energy. Getting through the day without a nap is tough. Getting through my workouts is tougher. Getting through an intense leg day is unthinkable.
Sleep. Food. Less cardio and stress.
Great video on an important topic.
Thank you sir for the free information!
Thnx Menno Really interesting!
really informative video
Here’s why to use the drugs in the first place as you pose in your last question. To reduce the constant gnawing hunger so that you can disassociate from it and THINK about all the unhealthy things you’ve been doing and think about all the lifestyle changes that need to occur to move forward. I was never able to make these significant changes because my need to eat over rode everything else. Taking this drug has given me breathing room. Room to look around. Room to study what I’m eating and how healthy or unhealthy it is. Time to plan and build new habits. Breathing room. It’s worth it for that. Stop the constant background noise and allow me to focus on making the most major lifestyle change of my life. It’s worth it for that.
I lost the same 40-50 pounds 3 or 4 times in my life. I started wegovy after hitting 260 a year and a half ago. Got down to 200. The plan was to take it the rest of my life but my insurance wont cover it now. Back up to 218 but I’m hitting the gym and trying to eat well.
Keep it up brother, just stick to it 👍
I had lost 97kg through lifestyle changes before going on Ozempic six months ago. So far I've lost another 13kg. Side effects such as stomach cramps and nausea were prevalent in the first 4-6 weeks, at first relatively strong the day after taking a dose, but then they disappeared. The biggest change I would say is that my desire to snack has almost entirely disappeared.
I d say good on you mate that feels like the understatement of understatements . Jeezy well freaking done sir.
Thanks very much, that means more than I can say! I feel incredibly fortunate that I took the plunge and got some health and lifestyle coaching, it helped me stick it out when I would probably have otherwise quit.
@@energonjunkiegood work. How long do you plan to use the med for?
At this stage? At least another 5 months, which will make it 12 months total. I can see myself using it much longer than that, but I do want to try coming off for a bit and seeing if the snacking urges come back.
I'm very disappointed for liking this video....too early. Wanted to give it another like further into the video due to the great information. Really great and important points that you make, especially when it comes to sustainability, which is probably one of the biggest problems for people trying to lose weight. Doesn't matter if you use a drug or some crazy diet or so, after all, you need to change your lifestyle, your thinking, maybe your environment and even some people you surround yourself with. Thanks Menno!
Excellent information - my SIL is on injections and has tried every fad diet of course sigh
Does slowing gastric emptying then mean nutrient absorption is potentially improved?
The nausea and the most acute side effects can be mitigated through a more frequent administration protocol. I.e daily or EOD injections. That is of course very hard with the pre dosed pens...
Just watched the video, not much discussion on the newest version of the obesity medication, the GLP-1/ GIP tirzepatide. 25% muscle loss data on trizepatide based on data from the clinical trials, "Is Weight Loss-Induced Muscle Mass Loss Clinically Relevant?"
[(Conte, et al., 2024)]. Also, anecdotally, lower reported side effects.
Thanks for covering both sides of this issue. Is there a way to get some of the benefits of GLP-1 without taking the drug? Would some change in diet slow gastric emptying?
There are many ways to reduce appetite with dietary changes, yes, such as a higher fiber intake.
Eat a bowl of low cal soup before your main course.
Correction - when you reach a new equilibrium you will have considerably more body fat due to the loss of lean body tissue and the return to the same diet.
Menno henselmans for Hollywood debut 🗿
Damn, the way my friends described it, it's too good to be true. I think one of them puked at his own dinner =/...Twice. I noticed he had A TON of muscle loss at the shoulders =/. I'm 24% bodyfat, but I don't think I'd ever consider taking this, seems like a waste of money. It is super expensive, $900 per month in Ontario Canada. It doesn't seem to be working either...I think the lifestyle change is the biggest factor, but this gives them an excuse for status quo.
Semaglutide is outdated. Tirzepatide is more effective since activate also GIP receptor and no digestive side effects.
Tirzepatide is outdated. Retatrutide stimulates GLP-1, GIP, and glucagon receptors.
I Have Worked For 10 Years To Rebuild The Muscle Mass I Lost During The Three Years I Was On Metformin.
I Was "Prediabetic" They Said, I Lost 100lbs And My Upper Arms Looked Like I Lived In Africa. I Could Squeeze My Upper Arm And It Was About 1.5 Inches Thick. I Looked Great, But Once I Hit 129lbs My Body Started To Shut Down... I Still Have Muscle Gain Issues And Now I'm Overweight From The Health Issues, Which Has Disrupted My Gut Biome. In A Much Shorter Story, Pharmaceuticals Are Bad For You, Even If They Claim To Save Your Life.😊
Hi friend, You are aware Africa has a population of 1.2 Billion with thousands of ethnicities spread across a landmass 3 times bigger than the US or Europe? When you reduce that many people down a stereotype it makes you sound as ignorant as if you said I’ve become fat like a European.
I’m not saying this to be combative but I hope it makes you reconsider your image of Africans / how you speak about large groups.
Hope you take it in the spirit intended. I’m sorry you had a bad reaction to metformin & I hope your health issues improve.
I'm obese and I've considered hopping on Ozempic. The reason I've hesitated is for the reasons this video discusses: is it really a sustainable long-term solution? I don't think so. Losing a shit load of weight through caloric restriction is easy, especially with meal prep and choosing nutrient-rich foods that help with satiety. Keeping it off long term when a lot of that weight lost was lean muscle is not as easy. I am trying to do it the slower, more sustainable way: long-term lifestyle and diet changes with essentially all weight loss being fat due to adequate protein intake and rigorous resistance training. If I fail and the consequences of staying obese kill me when I could have succeeded on Ozempic, I will have to accept that.
Theres a big benefit for many people of just getting the weight off so they can start eating normal. by that i mean many think "well im so fat theres no point in even trying". ozempic comes in, gets the fat off, and then they start to finally realize "oh shit i can actually look good" and it's only then that they can make eating well a priority. its often hard to prioritize eating well when you think weight loss is literally impossible for you and that you'll never achieve anything close to your goal.
btw good on you for doing without drugs like ozempic. thats without question the best scenario, but for many who really stuggle with weight loss (and the mental issues that go along with it) a kickstart like ozempic is what they need to even try.
I have considered getting my old man on it because he has trouble sustainably losing weight. I have instructed him how to eat and even wrote a meal plan for him to follow. He drinks quite a bit and doesn't really want to adhere to it. This would be like "training wheels" so he can at least just get the weight off and get immediate results, while I tell him to drink a lot less and eat a healthy diet for long-term success.
@@jeffbunnell9961 The thing is that it wouldnt be training wheels and you know it. As long as the drug exists, theres no real incentive to change your lifestyle. Just keep taking the drug. For him, it may be the only way to sustainably lose weight since it sounds like he's never going to change his diet. So he can just stay on the drug for life.
My Father In Law Is On Ozempic, And He Is Still Morbidly Obese Because He Doesn't Move (Gamer) & Only Works 20 Hours A Week.
Ozempic Will Give You Gastropariesis As Well.
I think the goal is to form a habit of leaving out dinner for example while on the drug and keep it after one comes off of it
A further point not addressed in your video that people might want to consider before going for these medicaments purely for weight loss is the moral aspect. At least in Europe there is currently such a demand for these medicines, that people who really rely on it for their diabetes cannot get it.
I’m taking ozempic, I have 0 side effects at this point. Where I live it costs about 100 euros per month and I’m planning to be taking it forever, or a better medicine as they become available.
I’ve been lifting for 10 years, done many diets, etc., etc. This medicine is a game changer and I don’t think you did it enough justice in this video honestly
Sounds like you’re getting the best use of these medications. I’m happy for your success.
@@frightfactoryYTthese drugs will be even better in 10 years
if uve been lifting for 10 years didnt you learn to control hunger by now? i fail to see the benefit unless you're really preping for a show and semaglutides make it easier on you mentally
I follow Dr Tyna Moore and she hypothesizes that our levels of natural GLP1 deteriorate with age. So yeah, struggling with hunger is an uphill battle and the glp1’s are one tool in an arsenal.
What better medicine g. Its a willpower issue. The only things that work are the ones not allowing you to eat anymore, not even just satiating you, literally not allowing you to eat cuse if u can you will. U need to find the medicine with a psychiatrist or something, cause this is just a symptom and if u erase it it will come in some other form
i`m curious if lets say you eat the amount of protein you should, if that would counteract the lean body loss
Should help but you still need to keep the calories up out of inadvertent starvation territory.
@Sam_Saraguy the problem is based on this and many other videos, that these drugs slow down diggestion, so if you "force feed" yourself 180g protein 180g of carbs, you would probably be full throughout the day, what impact would that have of protein synthesis
Taking it for live may not even be working. I assume that the body will adjust. If you take it for a year and the body doesn't get enough nutrients the hunger signal will probably adjust so you still eat as much as you did before, just with the drug. Similar to how most people get into a deficit when going to intermittent fasting because they aren't used to that style of eating. But you can learn to eat 3000 kcal in a few hours and gain weight on that too. If you start to eat more often and are still used to eating bigger meals, well ...
I honestly think-under a doctor’s care and with carefully dosed product-that DNP is far safer and way more effective than Ozempic for the average person. Yes, DNP. The drug that the pharmaceutical industry is trying to make into a boogeyman simply because they haven’t found a way to massively profit from it yet.
The problem in the DNP situation isn't pharma. It's stupid people. Just like with Ephedra. About 8 or 9 years ago a bunch of British researchers wrote a serious paper pretty much saying it has efficacy and is widely used UGL so we should consider legalizing it and make it safer by bringing it above-ground/white market. Went nowhere of course. Once these bans/illegal designations happen it's all but impossible to reverse them. Here's a quote from the paper (whole thing is on ncbi)
DNP deaths were caused by reckless use or incidental overdose; either by young individuals who suffer from some form of eating disorder or inexperienced users
Was 500, now 310. I know ozempic won’t help me, when I’m stuffing my face I know my stomach is already bursting. I don’t eat from appetite. I eat to cure depression loneliness anger frustration anxiety fear overexercising overthinking dehydration lack of sleep etc etc etc
1. Get therapy
2. Force feed yourself a big ass salad and a vegetable stir-fry 3 times a day
3. Get a personal trainer or coach who is specialized in eating disorders.
Done.
ALL your mental health issues are from a completely disrupted body. If you fix your lifestyle habits, your mental health WILL improve. You don't even have to try that hard to fix your mental health, if your physical health is on a good level. Seems like bullshit but it's true
AS this drug ist releasing insulin, you may develop hyperinsulinamea and Insulin resistance, which may lead to many health issues, even If you have low blood sugar.
Unfortunately, members of my family are having terrible side effects from Ozempic. Individual results will vary, obviously. Terrible pain as food seems to be pushed to one side of the her stomach…I may have phrased that incorrectly.
so if you take ozempic and work out to save muscle mass and get lean ? seems like an okay option for a cut phase
Theoretically, as long as you're hitting your nutrition macros, that should be true. The problem menno mentions is that its difficult to consume 200g protein while on these drugs.
I would say that is a very bad idea... from the weight loss 1/3 comes from fat, 1/3 comes from muscle and 1/3 comes from bone .... so yeah the drug causes you to lose "weight" but its not all fat, its just as equally muscle and bone ... this is a bad idea to take unless you are morbidly obese. but for someone who is just overweight, I would suggest avoiding it and do it the old fashion way of changing diet and moving more
@@adminintellidm6806would this still be the case if you’re hitting healthy protein macros?
@@thatf_inguy8220 nobody needs 200g of protein unless you're on roids
@@adminintellidm6806 not sure where you got that statistic. the decrease in bone density (and everything else) comes from undernoursihment. the deficiencies that exist are not equal and depends completely on diet and supplementation
I'm doing well with traditional weight loss strategies, but I tend to reach a point when my hunger surges and I feel a strong pull to rebound. I wonder if a drug like this would be good to take during an intentional weight maintenance phase (to try and adjust my body's set/default weight).
Since there is no such thing as the body's set weight, not really. But it can be helpful deep in a cut to finish your prep for whatever photo shoot / show you have.
Otherwise, the body gains and loses weight with how much you eat, and how much you eat is governed by nr.1: stress, nr.2: friends & vacations, nr.3: lifestyle.
Sleep more -> eat less because you don't feel you need it.
Go out more -> eat more because you drink alcohol and stay late and hunger signaling is really messed up when there's loud music around.
Eat when you watch TV / phone -> eat more because you're eating too fast and also not being aware of the food.
It's not easy, but it's just.. that.. simple.
There's a body set weight and it has been researched and experienced by thousands, it's not a set number but it's a range, and it might have to do with body composition, not just weight, but the range definitely exists @@floriancazacu4504
@@floriancazacu4504I was 140p for years eating like I want, never gained weight never lost, now over a couple of years I reached 165 with the same fat% and I still eat like I want, going down to 160 is a breeze, going any lower is just hell, and going above 170 is hell too
Just take diet breaks where you eat at maintenance until you feel better.
Facts 📠
Has this research opened up the door to any supplements that work in a similar way that might be beneficial for long term use?
Ozempic is too drastic and too short term.
But it seems there is new knowledge that might mean we get a supplement that acts as something akin to a "metabolism booster" and helps promote fat loss when combined with exercise. Almost like GLAs.
Has anyone identified such a supplement yet?
no thats an entirely different mechasism(s) of action
If you're in good shape, could you use this during a cut?
The gastric emptying part, does that mean that you're taking a shit less often? That could come in handy at work but come on, I enjoy my toilet time 3-7 times a day.
If you stop the drug your future body composition will likely be even worse for those who don't do weight training because you will not gain back the lost lean mass. That's one major negative effect I would add to your list
Nope it's even easier to regain muscle mass if you've "lost it" because the cells don't go anywhere. Muscle memory is real and it doesn't just apply to bodybuilders
@@blink182bfsftw this applies only if you do weight training and the average ozempic user certainly doesn't
@@sunttu333 how did they get their muscle mass in the first place, without working out, to lose it with ozempic? That's right, from carrying their weight around. If they gain that weight back there's no reason to assume they won't have the same body composition back
So from what I understand, I should just do Clen? 😂
Does it slows metabolism!?
Metabolism slows when muscle loss occurs.
So I'd answer yes it does slow metabolism.
"It" does not inherently slow metabolism above what dieting would... However, yes, the fact that you are eating much less does slow down metabolism. This is exacerbated by muscle loss from the mechanism mentioned in the video, loss of muscle definitely slows metabolism. That is one of the ways people who go off the drugs regain the weight
Great information as always and fairly laid out. The sad thing about this drug is that once again it is one more way that people who have issues of suppressing their emotions and trauma (which then causes responses like over eating ) are putting a band aid on the issue, instead of doing the work to get to the root cause. Once again , people are so focused on what they look like that they are missing out on what they feel like (mentally and spiritually) We need people to be healthy all the way around , not just have a good looking physique. And i find is disappointing that so many fitness coaches are saying do this when they knwo that people are losing lean muscle instead of fat. Because that does so much damage to a persons ability to keep the weight off, much like crash dieting does. Its a sad state of affairs that our society is so into the instant gratification way of life, because hard earned health does more than just give you a great physique, it also gives you a healthy mind and soul, which are priceless.
you say at the end "if you are going to change your lifestyle then why do you *need* the drugs in the first place" but i think that's a *very* narrow minded view, the point would be to make the transition easier. its not about *need* its about making it easier for people to simply start.
having a boost to your fitness journey at the beginning when it is ostensibly the hardest (for people who are morbidly obese and have difficulty walking, which would be the primary target of this drug). its much easier to make change when your joints have 100lb less weight on them, since moving your body is required to lose weight.
This is true and generally I agree, but there is an argument to be made that going through the hardest part of the process is necessary to create a sustained change. If you know that you can always go back on the drug, theres no real incentive to change for most people. That said, we have a major obesity problem and this drug makes sense for people who would never have had the will to start in the first place. At least they have a chance now. But, IMO, I think people should make a serious attempt to push through the beginning of their lifestyle change using fundamental principles of diet and exercise, not fad diets.
Yea, it's like painkillers. Yes, I can handle some ankle pain after straining it, but do you mind if I use some anyway? It's a tool after all
We don't need to make the transition easier for people. We need to properly teach parents and their kids about nutrition at a young age. Then we need to tax sugar and unhealthy fats more, make vegetables cheaper, make it more attractive to use bikes or to go by feet.
The healthiest countries are the countries where healthy food is more easily available and where you can easily walk or bike to places.
This is the entire problem. People are not biologically made to fight the power of nutritionally dense foods (sugar, refined processed crap, fats etc). We have to change the system, just like with climate change. Some guys driving a Tesla won't change shit, one guy succesfully losing weight won't change shit.
People will keep getting unhealthier and fatter in the countries where this is a trend. No amount of weights loss tricks, hacks or magic pills will change your biology
I'd love to be able to afford semaglutide. It seems wonderful. Had to go the oldschool way and it wasn't pleasant. Cravings and constant hunger are awful.
what do u mean by oldskool? u mean diet and exercise?
@@DarkoFitCoach Yeah. Counting calories, getting enough protein, weights and walking. It works, but it's a slog. Would love a ozempic shortcut.
@@JumaiPL yes but ozempic has downsides: nutrient deficiencies, side effects, LOTS of muscleloss even up to 40% etc
@@DarkoFitCoach Yeah, but as far as I understand, it's people keeping the same food habits, with less intake. I've got good habits going on, with vegetables and quality carbs. I just wish I could get rid of the hunger.
Can we talk about how people on these drugs have breath that smells worse than a dumpster full of rotten eggs on a hot summer day? What is up with that? Why and how is it so unbelievably bad?
interesting- is the use of these GLP1 antagonists considered natty?
no banned by WADA
watch the video before commenting lol. he answers this.
Incorrect information. 1. The research shoes it does NOT cause more lean muscle loss than bariatric surgery or other forms of restriction. 2. The evidence shows that while most ppl regain SOME weight after discontinuing meds, it is not all regained. Most who lose very large amounts of weight keep much of it off. And lets not forget that nearly every form of significant weight loss is associated with regain
Most people be looking for the easy way out.
So proud of you that you don't need it. You are an amazing person. So much better than all those fatties right?
Okay. What does doing things the hard way get you? Do you get an award at the end of your life? Do you go to some special place when you die? Or are you just creating an imaginary personal reward that only exists in your head and not in reality?
@SPRVLN27 society has mostly been conditioned to be quitters. When things are hard, it's not worth doing. Weight loss is no different.
It also isn't difficult when you stop making excuses and make a change. This video lists the negatives of just taking the drugs and not changing your lifestyle and habits. You're losing more weight from lean mass than fat, so you're only trading fat fat for skinny fat.
But no, there's no trophy at the end. When you die, you'll have died healthy and fit.
Its not yet clear in the scientific literature whether the massive health benefits of being lean is due to a high level of physical activity AND a low calorie intake or if its just the calorie intake doing the job. Before you disregard hypertrophy training or cardiovascular exercise- remember these things will help you more in the long run than a drug which if you stop taking- you’ll lose all its benefits due to the massive hunger surge
This is human nature. Why work hard and deprive yourself of delicious food when you can just take a weekly shot and carry on partying?
The only argument I can come up with, is the following; while making a lifestyle change, less suffering from hunger, may increase the success rate. Then once the new pattern of behavior has been adopted and the desired weight loss attained, going off the the GLP-1 will not result in regression with the same frequency. This would be similar to nicotine patch, etc. However, the suffering may be necessary to condition the brain and personality of the individuals to never want to go through it again thus creating a more powerful feedback mechanism. However, given the relapse frequency is incredibly high, with all addicts, it is very unlikely that any individual who requires medical intervention, for weight loss, will actually keep the weight off.
So basically, eat less. If you can keep your mouth shut and not stuffing junk in your face, then you don't need ozempic.
In the UK, you can get a prescription for these from an 'online doctor' who works for the shop selling the drugs 🤦♂️. There's already multiple accounts of young people who weren't even overweight ending up in the hospital with severe malnutrition.
brutal
Have you tried Lizzo? It's way cheaper
Menno says cut with Ozempic. Got it.
I think that with lifestyle changes, temporary use (1-2 years) of semaglutide is both safe and reasonable for anyone with a BFP over normal. However, lifetime use may not be cost-effective at the current price. But if the cost comes down to ~$100/mo., I can see half of the planet using it in the long run.
I have also heard there's significant psychological side effects like severe depression, and anecdotal stories of pancreatitis. Maybe the brain doesn't like being told it's artificially not hungry? The drug is powerful to save diabetic lives after all, but many think it's completely benign. Either way the lifestyle habits have to get developed eventually for people wanting fat loss.
Calorie restriction itself at some point might make you lethargic and less motivated to do things, not much of a suprise here
@@kacperpasternak3075 I believe there might be some unique effect Ozempic has regarding the psychological effects, such as messing with the leptin-ghrelin feedback loop, and thereby having an effect on the brain. I have dieted pretty hard a few times but wouldn't say it resulted in any kind of clinical depression (after having seen my brother deal with depression), merely a feeling a bit more tired. This is something that might become more evident with time.
There is no free lunch
Things will start to show up
You can bank on it
More reason to stay natty
Cancer incoming
Yeah actually we have no idea why it affects appetite, although it's almost certainly far more complicated than you state. Mounting evidence suggests it's a general drive inhibitor, i.e., it's more psychological than anything else.
Citation or delete please because this is a settled issue.
Obesity is a chronic disease which will usually need a life long treatment, so yes you are supossed to use some kind of treatment for the rest of your life and so far a GLP1 analog is one of the best alternatives
Please just stop. That's an Ozempic commercial not an argument.
The decision to designate obesity as a "chronic disease" was an arbitrary self-serving move by the AMA house of delegates at their 2013 annual meeting in Chicago. That specific enough for ya? No? How 'bout this: That decision actually went directly against the advice of the research committee the AMA established to study the issue. The designation is not founded in the AMAs own research or any other legit science or in reality. It's purpose was to make CMS/insurance reimbursement for gastric surgery and (waiiiiit for it....) these very weight loss drugs easier. Guess what occurs when that stuff gets easier? Doctor's and Pharma get more $$$. For the vast, massively overwhelming majority of people obesity is simply too much input and too little output. It is not a "disease." Period. End.
So your argument is literally: They willfully ignored their own research to fake designate something a disease for the purpose of selling more drugs, therefore, people should buy more drugs and take them for the rest of their lives.
You do see that now, right?
Put it in the water supply. Make the frogs shredded.
Fatto Menno 🤣
Taking ozympic is like cutting off your leg to lose weight. It works, but at what cost…
No it isn't wtf. It's like keeping unhealthy eating habits with some side effects to lose weight. You can't compare nausea to cutting off a leg
@@atherosclerosisheo3379 or loss of up to 40% of your lean muscle mass, destroying your metabolism and your health.
@@atherosclerosisheo3379 ahh the internet. its a turn of phrase not a literal argument.
yea if cutting off your leg somehow improved all your health markers
Tell me you haven't been in a WalMart without telling me you haven't been in WalMart. Or even a WalMart parking lot. topline indices of obesity are off the chart across the developed world, which one could attribute to "healthy lifestyle" advice proffered over the past 50 years. The giant role played by genetics, epigenetics, microbiome and environment (including food availability and expense) puts this relatively solipsistic viewpoint into trash can where it resides with other well-meaning, well-intended but simply ineffective advice and counsel.
If regular people can use semaglutide for weight loss, then it should be ok for body builders. Meat heads may be an even better use case, because they'll use it, hopefully, for just a short time. I wonder if semaglutide will usher in yet another body building influencer wave where they are at 5% body fat? Or maybe there will be less of a need for weight lifting influencers, because now anyone, barring side effects, can somewhat easily drop weight.
so maybe next time watch the vid before commenting b/c he literally said this.
"If these drugs get cheaper"
(Laughs in capitalism)
can't this be microdosed?
Hahaa. Most effective drug for weight loss... 10% with half of the year of bodyfat. Are you kidding me? Most effective weight lose drug is doing meth or heroin 🤣 when side efects are not important. I think it was Peter Attia who said, nothing helps you lose weight like a good heroin addiction :D
Your APPETITE goes BACK TO NORMAL once you STOP taking this CHEAT DRUG. If you have a naturally FAST metabolism and/or you train hard (heavy weight and intense conditioning), you DON'T have to count calories, watch portion sizes or avoid cheat meals. You DON'T have to be obsessive with diet then. You can just enjoy the challenge of tough training.
But most people WANT/NEED an easy and quick fix. They don't have that intrinsic motivation to MAINTAIN a TOUGH (progressive) regimen. So, if they DON'T continue to take these CHEAT drugs for a lifetime then they'll just go back to what they were originally - WITH a SLOWER METABOLISM. Why are people always looking for an easy and quick fix?? This just proves HOW MUCH people WANT HOT BODIES. We ALL view STEROTYICAL HOT STRONG bodies as the TOP of the totem pole. And if they DON'T have that, or NEVER had that? I imagine they lack body confidence.
OzemPigs lmao
Unhealthy cheater pill