5 things you can do now to reduce dementia risk | Professor Claire Steves
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- čas přidán 28. 04. 2024
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How early should you start taking dementia seriously?
In today’s episode of ZOE Science & Nutrition, Jonathan is joined by Professor Claire Steves to explore the multifaceted world of dementia. They delve into the significance of dental health, genetics, impact of diet and physical activity. By exploring the latest research, this episode will give you practical strategies for dementia prevention.
Claire is a consultant physician in geriatric medicine at Guy's and St Thomas' NHS Foundation Trust, and a senior clinical lecturer at King's College London. Claire is also deputy clinical director for the Department of Twin Research and Genetic Epidemiology. She leads the characterisation of physical and mental aging traits and frailty in the cohort.
If you want to uncover the right foods for your body, head to zoe.com/podcast and get 10% off your personalized nutrition program.
Follow ZOE on Instagram: / zoe
Timecodes:
00:00 - Introduction
01:26 - Quickfire questions
02:42 - What is dementia?
04:18 - Control over fate with dementia
06:52 - Why older people get more fractures
08:32 - Warning signs of dementia
09:55 - Unique aspects of dementia
12:12 - Cellular level discussion on dementia
15:49 - Risk factors for dementia
16:07 - Inheritance and dementia
18:29 - High-risk factors for dementia
19:15 - Fetal development and dementia risk
21:47 - Brain reserves and mental health
24:24 - New advances in dementia treatment
30:47 - Medications and life expectancy
33:21 - Diet and dementia prevention
35:58 - The role of physical activity
39:45 - Oral health and dementia
42:10 - Social interaction and brain health
44:02 - Diabetes and dementia
45:36 - Women, HRT, and dementia
49:09 - Recap: types of dementia
53:39 - Hearing aids and dementia prevention
55:39 - Episode sign-off
Studies related to today’s episode:
Brain-age is associated with progression to dementia in memory clinic patients from NeuroImage Clinical www.ncbi.nlm.nih.gov/pmc/arti...
Interested in a specific aspect of dementia? Email us at podcast@joinzoe.com, and we might cover it in future episodes.
Episode transcripts are available here joinzoe.com/learn/category/nu... - Věda a technologie
1. Diet (plant-based, fibre, healthy fats)
2. Going for a walk every day
3. Look after your teeth
4. Social interaction
5. Avoid Diabetes
Also: hearing aids help prevent onset of dementia.
You’re welcome.
The diet doesn’t have to be plant based but fats used be plant based not saturated fat.
Oh thank god! Appreciate you doing this, this interviewer is driving me crazy
@@kestag2110 What are you trying to say?
How should we look after your teeth? Avoid sugar, and brush well twice a day with fluoride?
@@katherinekelly5380 I know. Rage inducing. Everything about him makes my skin crawl.
As others have said, it becomes difficult to follow this very interesting conversation with the level of interruptions. I absolutely appreciate the aim is to clarify what's being said, but I would like to hear complete sentences from Professor Steves because they might actually make things clear enough.
So true!
I think I have noticed he does it more with females he is interviewing than males. I'm a retired scientist and trained to look at this sort of thing but I'm not going to waste time going through interviews and counting it all up.
PLEASE stop interrupting the guest.
Fascinating discussion. Would have been better if the interviewer didn't keep interrupting/cutting off Professor Steves.
Wholeheartedly agree. She's clear. Why is he constantly interrupting her to dumb it down. Her momentum is halted and his explanations are insulting and unhelpful. I mean, 'cognitive reserve' isn't quantum physics and then relating it to gas in the car...ffs.
Don't agree at all. Jonathan's a brilliant interviewer.
It makes sense for the interviewer to keep the language as simple as possible so that EVERYONE can access the information, not just people with experience and knowledge of scientific terms. I want to live in a society where everyone can be helped to improve their health.
There was a lot of neurological disease science specific jargon in this, or are words like proteinopathy something you use also use in regular speech? If so I understand your comment, otherwise J is doing a fantastic job in keeping this understandable to a much wider audience.
@@jemima9384 I have no problem with him reviewing and simplifying the information given. It would have been more helpful if he let the her finish her sentence and then give the clarification.
I accept that its useful to have a non expert sum up when needed, but really J speaks far too much and it becomes very irritating. Claire is perfectly able to explain things in a way in which most of us understand.
Very interesting and useful subject to explore.
I agree, the interruptions and summing up for the thickest of the thick, just made me move on to something on youtube less irritating.
Agreed!
Absolutely. At times I think I'm done listening to these podcasts because he's so irritating.
These remarks are true yet I felt he did a fine job b of reviewing and hearing two different souls speak adds more recall than listening to just one person speaking 51:33 😊
Agree, he talks way too much!
Professor Steves is very interesting, would be nice to hear her in full flow.
I’m relieved that others have also noted that Jonathan talks over and interrupts guests frequently.
It really interrupts the flow of expert opinion and advice coming from the guest and disrupts my ability to absorb and process the information.
Whilst I’m sure his intentions are good, his approach disadvantages rather than benefits the audience and defeats his own desire to ensure valuable advice to listeners
Yes, he's unfortunately quite annoying and affected as an interviewer, and also not *the* Zoe founder as he said, but one of three founders. So a tad dishonest and disrespectful to others on the team. He's probably too busy, but I think Tim would do well.
Maybe he will read the comments and correct his annoying behavior.
I think I have noticed he does it more with females he is interviewing than males. I'm a retired scientist and trained to look at this sort of thing but I'm not going to waste time going through interviews and counting it all up.
He is a bit self-important. My view is he will not modify his approach unless there is a coup and his place is taken by someone more amenable.@@johncarter1150
I wish the guest would be allowed to complete a sentence without being interrupted!
But then how would you know how smart the host thinks he is?
And how dumb he assumes his audience is, since he feels he needs to restate (multiple times) in ultra-dumbed down language every single thought the guest expresses so we plebs can hope to follow along. We get two minutes of the expert, then two (or more) minutes of elementary-level regurgitation of what the expert just said, that we all plainly heard.
I found his interruptions terribly confusing ... do I have dementia?
@rebeccalecomte3770 , no, i wouldn't bet on that.
Has an expert on and he speaks more than the expert!
I wish the host would let the conversation flow a little more and let the guest direct the conversation at times so we can hear what this wonderful guest has going on in her mind.
Please stop interrupting professor and let her speak. He constantly stops her in mid sentence ! So annoying.
Most folk learn and retain more effectively from listening to conversation as opposed to fiction, it's more laid back, there is clarification and repetition which most people benefit from when up taking new information.
Diction*
Yes!!
I hate the cut off intros so much. It's incredibly annoying.
There must be evidence that it attracts people as it seems to be getting more common but I find them irritating.
It seems to be since Steve Bartlett invested with them and has obviously suggested they do this on the videos like he does on Diary of a CEO.
He always does it, really spoiling the videos
I'm much more likely to watch a video if I hover over it and it shows me a few highlights at the start so I can judge if it's worth my time. Your complaints arent going to stop them doing what is proven to be effective, so get used to it.
Tap foreward?
This expert is quite capable of explaining her field of expertise clearly without constant annoying interruptions from the interviewer !!!! He spoke 2/3 of the time!
Claire is very knowledgeable and very interesting to listen to and I wish she was allowed to finish her sentences. Jonathan seems worse than usual this time, interrupting and forcing through his sentences even while she is speaking.
A close relative passed away recently after being a dementia sufferer for nearly 10 years (with symptoms actually starting to show a bit earlier) but that was vascular dementia, in most likelyhood caused by oxygen deprivation during a heart surgery.
Agreed. And it is a sad tend with Jonathan. He is more condescending and irritating day by day.
Simply cannot let the guests share their vast knowledge with us.
I watch/listen to less and less Zoe podcasts with tone. Nowadays I pass on most.
And they aren't listening to us.
If narcissism would hurt Jonathan couldn't stop screaming in agony.
I am also sorry for your loss. I think most people listening to this "interview/conversation" have someone in their life effected by dementia. And adjusting or own lives to avoid it is also a priority.
But Jonathan makes it extremely hard to finish this "interview".
Zoe should hire someone capable to make the podcasts and he should move to back office.
I'm so sorry you lost your relative, I recently lost a much loved Aunt with vascular dementia too, though it was actually Covid that took her. In her case the dementia came on suddenly after a hip operation, then worsened noticeably after the second hip op. I googled vascular dementia and was startled to find it happens relatively often after general anaesthetics when older, though ops throughout life are cumulative. The more you have, the higher the risk. No-one mentioned this before any of my general anaesthetics, as one of the potential risks. I do think it should be better known.
I agree.there's a balance and he overstepped many times this time. He stopped her exlaining and then we missed out on that. He should let her finish and then clarify .
Like most comments here: let' Claire Stevens talk and stop interrupting!
Yes he is annoying
Too much talking by Johnathan!
Glad to see others commenting the same already. Way too much interruption, cutting off, butting in with explanations. I get you need to explain in layman's terms. But really some of the points would be more clear if you let the guest finish her point first...then reflect any comments back. Or clarify with the guest beforehand what terminology to use/avoid perhaps? I never comment on CZcams but felt the need to with this one.
Very interesting but I do wish Jonathan would stop interrupting and talking over the presenter
He’s dreadful
Surely it's an interaction he is taking the place of the listener who may want to ask those questions to the expert, otherwise the expert is just making a speech x questions
I find him very condescending, and whats alllll theee exgerating...... ( pause) words
I agree. I can barely stand to listen to his interviews anymore. I asked him nicely in a comment to please stop talking so much, but to no avail.
@@suzangroves959 yes, good point but the interruptions in mid sentence are annoying
My mother died recently aged 95 with mixed dementia, osteoporosis, type 2 diabetes, ulcerative colitis and Crohn's disease. Her sister is still going strong aged 93 and looks 20 years younger. The difference being she walks 2 or 3 miles a day, is sociable and doesn't have diabetes. Mum was shy, ate the wrong things and alrhough never obese, didnt do any exercises, preferring to stay home and knit ...
So sorry to hear you've lost your mother, and wishing you peace of mind
So very sorry for your loss. My own mother passed this week and she had dementia for a long time. My deepest condolences to you and your family.
Very informative thank you but Jonathan should not be interrupting the lady this often
Yes, I appreciate the topic may be close to his heart, but he was actually rude this week, interrupting her so often it was painful.
@@jecookdale6793 I agree -- people think their audience won't follow or won't know what a word means or won'tt follow the argument, so they butt in and give their view. Patronising as well as rude.
@@NSBarnett He's no Michael Parkinson as an interviewer. A good interviewer knows when to keep quiet in order to extract additional information. The excitable Johnathan can't wait to jump in, often asking the same question in a number of different ways before letting the interviewee continue. This 58 minute interview could have been done in half that time with a bit of editing which would have achieved the same measure of information and been more interesting.
Even if it looks like this, it's not about interrupting the conversation, but about being inquisitive and asking important additional questions, for which I really appreciate the presenter. Your goal is to learn as much as you can from the podcast, not just listen politely
@@NSBarnettexactly patronising and rude.
Also the arrogance of assuming what the audience wants to hear. I want to hear what the professor has on her mind, not what the host thinks I want to hear, and proceeds to yank the conversation towards.
Jonathan, I know you're the founder and all - and I DO enjoy the podcasts. But for the love of nutrition, PLEASE stop interrupting your guests.
He's getting worse and worse at this. Making the podcast about him, rather than the topi/guest
I totally agree - it was so annoying and SO rude to his guest.
Indeed, that and 'mansplaining'!
I think he’s doing it because he believes they’ve said something that needs further explanation for the non scientist, but it would be better if they were allowed to get to the end of their answer before then asked to clarify any technical terms.
He does NOoT interrupt for no reason. He EXPLAINS IN BITES -AS IT SHOULD BE- for those ch people who are not sed to listen to speciamised languag. Well done Jonathan!!!!!! wh
When Jonathan has guests on this channel it would be interesting to hear from them instead of all of Jonathan's self-interested meanderings.
We all process listening and learning differently but for me I like to listen to the uninterrupted flow of an expert who is incredibly knowledgeable. Also Jonathon does tend to use 10 sentences when one would do. He over explains and the interruptions are just not working on overall understanding. Is there an ego problem?
Jonathan doesn't need to repeat everything the expert says - we're listening, and if we miss something we can rewind. Worse than usual this episode, presumably because he had a personal interest. So we learned about what pregnant women should do and those in their 40s,but that was pretty much it.
I hope Jonathan reads these messages and lets the guests talk more than he does from now on
Personally I find his questions extremely helpful!
I love these Podcasts but Jonathan, you are starting to speak too often and over-clarify. You are doing a great job but there’s a fine line between clarification and stopping the flow of the specialist. ❤
I agree with other comments about the interviewer; the content is fascinating but the excellent interviewee is overshadowed too often. Interviewing is a skill, let's find one who has the ability to draw out the expert and not be so irritating that it will put people off listening to the important and fascinating content.
What he is doing is getting repetition to make sure the listener hears n understands d important points
I’ve listened to Zoe from the beginning but I ‘m tired of the continuous interruptions from Jonathan .
Yeah!! Replace the host--immediately!!
Agree!
I agree with the previous comments that it's a great shame that a highly knowledgeable and interesting professor is continually interrupted. I wanted to hear so much more of what she had to say and the interviewer didn't really listen to her and cut in several times just as she was abiut to say something important. This is a topic close to my heart as my mother has dementia. I'm going to see if I can find an interview with this professor conducted by a more professional interviwer.
Good idea. My Mum has had dementia for over 20 years. I do everything I can to prevent it.
Why does Jonathan keep interrupting the expert? I'd love to also hear the ends of Prof. Steves's thoughts.
Wow what a brilliant person. Claire’s clarity is incredible. So yes we did not need so many recaps from Jonathan as it was all already pretty clear (I guess a topic close to your heart gets one a bit too excited…😊).
Whilst clarification is useful, continuously talking over your guest is rude and extremely frustrating for the listener. Your guest is the reason why we are here.
Professor Claire Steves is very gracious responding to the continuous stream of interruptions
If I visit an expert obviously it makes sense to remain silent and . . . LISTEN . . . i.e. keep mouth firmly shut
As others have said, this video has been spoilt by the continuous stream of unnessary interruptions
Johnathan is usually very good but in this episode he seemed super stressed and he didn't give professor Steve's the chance to talk....I felt there was more that she had to say but Johnathan kept cutting her off.
Ok, you feel Johnaton's usually very good but many feel he always interrupts the flow of these podcasts by constantly interrupting the expert to offer his inane comments meant to help but really only hinder.
JW is the main reason I only view these podcasts only occasionally. His inane comments add nothing to proceedings.
I get the impression that he is, as you say, super stressed. I feel it’s because he’s extremely worried about getting dementia himself
Some constructive feedback - could the interviewer please stop interrupting the guests (not just the guest in this podcast) so frequently. Keeping them on track is important, but overdoing it is irritating.
Interrupts and then repeats what he was told in a different more rambling way.
@@armed_but_blind2768sometimes inaccurately, which is worse because the guest has to repeat the point
It’s incredibly annoying how much the interviewer is interrupting and cutting off this brilliant woman.
Claire was really interesting and informative, but the interview was ruined by the extremely poor interviewer, who was constantly interrupting her, and explaining everything again, after Claire had already been vey clear! He did most of the talking and it was extremely irritating!
Have only just joined, and thought Jonathan was the interviewEE😂
Brilliant guest!
I like the conversational style rather than a lecture. Keep up the excellent work Jonathan. And may you live to be a healthy 90 year old!
I like it too, I leave it on in the background and the clarifications help the information go in while I'm doing other things, this has been the style of this channel all along, strange to see all the whinging now lol
Johnathan thank you for these fascinating and for me very beneficial podcasts. May i make a serious request though - PLEASE PLEASE PLEASE just sit on your hands when you are talking to your interviewee. Thanks so much.
Yes Jonathan is irritating in the way he unnecessarily over explains. Dumbing down the content. Not necessary. For most of the folk listening to this. Sorry Jonathan - work on only unpacking in this way if you are confused… most of your experts are very understandable
Exactly.
Exactly!
Shocked at how poorly they understand their audience. At least they have a large segment who need more technically in depth content.
He interrupted her to explain what haemorrhage means, he’s just so off the mark.
Sorry I disagree. Unless you can ELI5 then you can't truly understand the info. If he didn't do that, then this content would be far less accessible.
Disappointing that there was no follow up question to Claire's statement that women are more likely to get dementia than men!
It's worth watching Rich Roll's interview with Dr. Lisa Mosconi
It's down to good old estrogen
Agree with so many of the comments - the interviewer really needs to curb his interruptions and let us listen to Professor Steves.
Jonathon has been so annoying during this discussion constantly interrupting and talking over. Dreadful interview skills
Usually I appreciate Jonathan's interruptions but he doesn't nee to reframe everything. She is a good communicator and he didn't need to constantly interrupt. He has made it a difficult interview to listen to.
Interruptions may be partly due to personal anxiety specifically about dementia, alluded to by the revelation of Grandma’s dementia and Dad’s fear thereof. Pray she rests in peace, confident the host will absorb the feedback, grateful for such high quality health advice being available for free.
“It’s one of the diseases I’m most scared of having” direct quote, missed that the first time. I see this a lot with patients; what may appear to be rudeness is actually a (often very justified) fear.
Let someone else interview?
I believe there is a connection between the gut and the brain. However, my brain / memory/ recall has been noticeably improved since I upped my fatty meat intake. I tried a high fibre / low animal fat diet for many years, but gradually my recall deteriorated. My teeth have also improved since I reduced my sugar/carb intake. I’m 64 and feel better than I did in my 50’s.
I wish the host would talk less and allow the guest talk more since she is the experts ! It's a great subject !
Thank you Jonathan for your questions & summaries, as I find your style helpful to my understanding. As I approach my 80s & I'm permanently exhausted, my brain is slower than it used to be, therefore I'm grateful for what others define as "interruptions", "mansplaining", & unnecessary. I enjoy how you interview these experts, as they don't use ordinary everyday language; you help me understand more easily. I wish to live well as I age, and to be able to care for my health to the best of my ability. Everything that you bring to my awareness is an enormous help.
Thanks for sharing your point of view
Excellent in so many ways: highly relevant topic, knowledgeable guest and clear good advice. Jonathan, please try and ask more succinct questions without the long ‘back-story’s.’
I love Professor Claire's style and attitude and straightforwardness and integrity. What I missed in this presentation was a lack of analysis of the impact of processed/highly processed foods and a look at why diabetes and cancer and heart disease etc have all rocketed in UK and US populations since the 1970s. To be colloquial: What's that all about? What's the significance of those substantial rises across the board?
Jonathan, stop interrupting someone who knows more about this subject than you do.
Agreed. Sorry but these comments been made before. Quite rude!
Yes, Jonathan is so scared of getting Dementia. He almost turned it into a Q&A for him. I can understand that too.
@@carolbarrett5132 But that is no excuse for mansplaining. Thank you for your very informative explanation.
This is not mansplaining at all. There was a lot of neurological disease science specific jargon in this, or are words like proteinopathy something you use also use in regular speech? If so I understand your comment, otherwise J is doing a fantastic job in keeping this understandable to a much wider audience.
*SUMMARY:*
*What is a dementia?*
04:56 *A **_dementia_* is a condition that involves *_cognitive functions_* (of thinking, learning, memory, more than one domain of it) which is *_altered_* to such a degree that it *_causes problems in day-to-day living,_* and it *_gradually progressive_* over time.
05:16 The condition need to be existing at least for *_6 months_* or more, to be called a dementia.
*Dementia vs. normal aging brain:*
*A) Normal aging brain:*
- 06:13 There's *_brain atrophy_* in the older people.
- 06:28 *_Slower processing speed_* in older adults.
07:26 That's why when some older people (the *_younger_* ones) fall, they would *_fracture their wrists,_* while others (the *_older_* ones) might *_fracture their hips._* The _younger ones could move their hands quicker_ to protect their body.
*B) Dementia:*
- 09:10 *_Short term memory loss._*
- 09:18 *_Not able to function in normal activities_* of daily life.
e.g. 09:22 Not able to manage _finance_ or _medication._
*What is the cause of dementia?*
10:13 The most common *presentation and cause* of dementia is *_Alzheimer disease._*
Symptoms: *Not much change* in *physical appearance* or *mobility,* but that person would have *_short term memory loss_* (like, asking the same question again and again).
*What does happen in the brain with dementia?*
12:11 There's *_inclusion/deposition of a certain protein_* either inside of or outside of the cells.
55:53 There are *+/-25 types of dementia,* such as:
- 55:46, 10:13 *_Alzheimer_* is the most common type of dementia.
- 37:39 *_Vascular dementia._*
13:02 *What does differentiate each type of dementia?*
- The *_type_* of deposited *_protein._*
- The *_brain area_* where the protein deposited.
- The *_pattern_* formed by the deposited protein.
Progress of *drugs treatment for dementia:*
- 29:31 There's a *_new antibody-based drug_* which removes protein from the brain which could slow down dementia process, with some risks:
-> 31:35 *Edema:* swelling in the brain
-> 31:45 *Micro-hemorrhage/micro-bleeding* in the brain.
- 48:18 *_Hormone Replacement Therapy (HRT)_* is *not going to be the cure of dementia,* but probably *contributes to the cognitive reserve.*
27:34 *Early symptoms of dementia:*
*1) **27:58** **_Short-term memory loss_* --> Alzheimer.
*2) **28:03** **_Personality change._*
*3) **28:11** **_Falling over._*
*4) **28:15** **_Difficulty with the blood pressure regulation._*
*5) **28:19** **_Difficulty with sleep regulation._*
13:41 *Dementia vs cardiovascular disease:*
- *Similarity:* Both have *_accumulated substances_* in the body, mostly due to chronic poor diet.
*- **14:19** Difference:*
*-> Cardiovascular disease:* The accumulation is on the *_artery_* and *_blood vessel lining._*
*-> Dementia:* The accumulation is on *_neuron cells_* and *_neuron supporting cells (e.g. microglia)._*
16:54 Who does *have greater risk of dementia?*
*1)* 17:37 People with *_APOE 4 genes._*
18:23 APOE 4 genes affect *_how the brain cells use fat,_* and are *_influenced by our diet & medications_* that we take.
- 18:03 25% of people have 1 APOE 4 gene.
- 18:08 2% to 3% of people have 2 APOE 4 genes. 17:50 These people have *_8x greater risk_* of dementia.
*2)* 20:33 People with low *_cognitive reserve._*
20:36 *_Cognitive reserve_* = maximum *_cognitive ability (intellectual & psychological)_* that we might have.
19:56 *Cognitive reserve* should be built since *_fetus and early childhood,_* because:
20:56 If we start off with really high functioning --> we build a lot of cognitive reserve --> we might get dementia much later in life.
Examples of people *who might have low cognitive reserve:*
- 21:50 People *_whose mother was drinking alcohol or smoking_* while pregnant with them.
- People who were *_under/malnourished_* in childhood.
- People who grew up in *_dysfunctional family_* (suffered from *_abuse or neglect)._*
26:39 There are *strong interactions between brain and other body systems:*
*1) **26:50** **_Brain & hearing/sensory ability._*
Decrease in hearing or sensory ability --> *reduced stimulants for the brain* --> increased risk of dementia.
*2) **41:47** **_Brain & teeth._*
42:02 There's a strong relationship between periodontal disease and cognitive health:
*a)* The teeth are located very close to the brain. *Harmful germs in teeth cavities* or gums could easily enter the brain.
*b)* 42:26 It's a *viscious cycle:* Dementia makes it difficult to take care of teeth --> Bad teeth makes it difficult to eat --> *less nutrients are absorbed* --> dementia is worsening.
*3) **26:45** **_Brain & cardio-acrobatic health._*
Healthy cardio is crucial to pump blood to the brain --> ensures *brain gets enough oxygen & nutrients.*
*4) **37:28** **_Brain & vascular health._*
*Vascular health =* The health of *_the blood vessels_* within your body, including within your heart.
*5) **_Brain & digestive system._*
36:22 There's a *brain-gut axis* in the body, which means what happens in the brain affects the gut, and vice versa.
*6) **_Brain & immune system._*
27:02 *_Infection & chronic inflammation_* can affect how our brains resilient to those changes which might happen in that balance between proteins being set down or not.
*7) **_Brain & metabolic health._*
46:12 Having *diebetes significantly increases* the *risk of* having *dementia* of all types.
46:22 People who *have both dementia & diabetes* should be careful in *managing blood sugar level,* because *low blood sugar is dangerous for dementia.*
24:05, 35:31 How to *build/increase cognitive reserve* to delay/counter dementia, especially _since fetus & early childhood:_
*1) **21:38**, **24:13** **_Dietary nutritions._*
*a) **35:50**, **36:29** Eat **_fiber & many different colors of fruits & vegetables._*
Purpose: To *feed gut microbiome.* Because of *_the brain-gut axis,_* what happens in the gut affects the brain and vice versa.
*b) **35:55** Eat good **_plant-based fat._*
Purpose: To support *brain metabolic activities.*
*2) **21:22**, **24:14** **_Intellectual stimulation,_* through *education & parental influence.*
*3) **21:31**, **24:17** **_Psychological balance & stability_*_ (a.k.a. mental health)._
*4) **24:59** **_Healthy social interaction._*
44:19 One of *the most complicated things we do* in our brains is to really *interact socially.* It is even better than brain games.
*5) **25:07** **_Physical activities/fitness._*
- 25:45 *_Reduction in sedentary time_* has an effect not just on *dementia,* but also on *brain aging.*
- 38:58 *_Going out everyday._*
- 38:53, 41:03 *Exercise* at least *_walking_* for *_45 minutes 3x a week._*
- 45:17 Physical activities which are really good for cognitive task: *_table tennis, dancing._*
- 26:39 Physical fitness also includes *_taking care of other body systems,_* because of the *strong interactions between brain and other body systems.*
I was so surprised when this video began that Jonathan Wolfe is the CEO. I recall working with you many years ago in the venture space for technology. So glad you have begun this venture.
Not only people from the UK and US are watching these episodes, you know. You could integrate some other countries in the statistics. Thank you for your work. I enjoy every episode very much !😊
👆
Claire mentioned infections and inflammation as risk factors. Vitamin D deficiency is an endemic problem; and yet Vit D plays an important role in modifying inflammation and immune system effectiveness. Very simple and cheap risk factor to rectify that always gets overlooked.
Having healthy GUMS as well as teeth ie treating any Periodontitis (gum disease) by maintaining good oral hygiene, smoking cessation, no/ low alcohol consumption, as well as regular visits to your dentist and hygienist is key.
Thank you so much Professor Claire and Mr. Zoe for the great health analysis about dementia. ❤
Grateful for all the interesting, up to date science info and I am reassured I'm already doing everything I can to lower risk.
So the lack of dentists is a also risking many more more people getting dementia. The is horrific!
Thank you so much, both Claire and Jonathan.
I'm just now seeing this, it is so intresting. It appears that some people were expecting a lecture, I'm sure there's another channel for that. I can enjoy the back and forth, somewhat the kind of interactive thing I enjoy. We have a host, we have a guest, we have two very bright minds giving a full perspective. Thank you for all this enlightenment. If I wanted a lecture I would go elsewhere.
Thank you both professor Claire and Jonathan, lots of very helpfull info 😊
Great podcast, as usual. Thank you. So helpful.
The pre-diabetes / diabetes connection is clear from this interview (45:00). Reducing carbohydrate / blood glucose levels is essential for overall health. And not forgetting the vital importance of Omega 3 fatty acids (DHA in particular) naturally obtained primarily from fatty marine fish. Professor Michael A Crawford (of Imperial, London) has been “banging-on” about this for more than 50 years!
This is so. Alzheimer's is literally being referred to as type 3 diabetes in serious medical circles.
Thank you for that information. I get Omega 3s, but am not sure how much is recommended... I know my doctor thinks I need less vitamin D than I think I do...
@@marybusch6182 You’re probably correct re vit D levels. The norm was set decades ago to prevent rickets. These days we know vit D is essential for the immune system enabling it to attack viruses and bacteria etc. The modern norm now is suggested to be 100IUs per 10Kg body weight taken daily. I weigh 90 Ks and take 9,000IUs daily. Check out Dr John Campbell’s informative and fascinating You Tube discussions with consultant Dr Grimes ‘How much Vitamin D should I take’ & ‘The second pandemic’.
@@marybusch6182 minimum EPA+DHA 1000mg/1gm once a day
Plus these days with the contamination of our oceans with heavy metals and forever chemicals it's better to eat omega 3 from algae 👍
Thanks for the information Professor Claire Steves, but please manage Jonathan next time!!
What a fantastic guest is Professor Claire Steves. Really loved hearing her speak. I wish she has more long form video content.
Thank you both so much for this fascinating and very helpful exchange. I'm making great strides but will endeavour to do more! x
It would be interesting to know why urinary infections seem to make dementia much worse. My grandmothers dementia definitely stepped up a level every time she got an infection but I don't know why that happens 🤔
The UTI if not treated travels to the brain. Some UTIs don’t cause any symptoms until you have kidney pain, or your brain gets weird. If you find that you are going to the restroom more often, but little comes out, get to a dr to detect and treat your UTI. UTIs travel to the brain in men also.
I get more clumsy going up the stairs or walking around the block on the sidewalk. If that happens, I get it checked out.
With dementia, they forget to drink, being dehydrated brings on the UTI.
Inflammation caused by the infection. Inflammation is a response to infection and impacts the brain.
That has happened to our neighbour as well. She did say inflammation was bad.
Thank you for this information regarding dementia. My mum suffered with dementia from the age of 68 till she died at the age of 76. It was really hard on us her family and has always been on my mind if I will have it too. I will try and follow this information for my own good and my family too. Thank you 😊
Thank you for this informative broadcast.
Was diagnosed early onset 20yrs ago but do not have the gene. Young prof had interesting stuff to say from about 20 mins in. That bloke with her was a spare, but yeah I wouldn't have watched her without the Zoe branding.
I have mri scans of my brain. I'd love to know how to interpret the scans.
You seem to be doing excellent with your typing and computer use!!!
I have to say this interview is soooooo CONVOLUTED !
Very interesting! Thank you 🙏 going through the process right now of getting my mom tested. She currently has the issues you’ve mentioned, short term memory loss, inability to manage medications, and household appliances are now a challenge. Very difficult to manage the process here in the States.
Two examples of slow reaction time in the very elderly (by the way, I'm 76). In Vancouver BC I was walking and witnessed an '"accident." A man was in the process of parallel parking and somehow slammed into the back of the car behind him. He then reversed gears and slammed into the car in front of him. This back and forth slamming continued until someone walked across the road, opened his car door and turned the car off. The guy just couldn't process what was going on and come up with a decent solution - put on the brake, put the car in park, and turn the engine off. He was advanced in age.
Another time I was waiting for a bus in an area that was covered by a building, the location was a major bus exchange. A woman came driving into this area, very slowly. The area was restricted to all vehicles except buses. She then proceeded to drive up on the sidewalk while people scattered, very slowly I might add, taking a bit of time bringing the car to a halt. When the police arrived they had her walk to a cop car. Due to her age, quite old, she could barely walk and had to be assisted. She had entered the area with low lighting and that disoriented her, she couldn't process what was going on and the inevitable occured, with no one hurt fortunately.
Think there's an age at which one should no longer have a driver's license. Also think no one should be in high office after the age of 70.
@@hagbard72 I believe that drivers testing/evaluation should be mandatory based on a doctors recommendation.. The family does not necessarily want to be in that position and the auto insurance could request this information after 65... its hard to know when it is going to hit or how quickly it will progress and even regress... remember Dementia may be reversible... Any doctor worth their salt realizes the response times and whether the mental processing is logical based on a 20 minute interaction during a routine visit... My doctor sends my prescriptions electronically and could do this as well in minimal time to insurance companies and the insurance companies could let the MVA and the patient know that they should be evaluated... I have to report my mileage every year to the insurance company to maintain my premium reduction for decrease mileage...
Hate to say it, but this is a bit Orwellian, but it is a safety issue and there are massive numbers of boomers getting well past their prime..
@@hagbard72 There should definitely be yearly tests for elderly drivers, including rigorous cognitive and reaction-time testing. It might be unfair on some (I've known drivers in their eighties who were sharp as tacks in every way), but the more rational will understand the reason. Unfortunately, so many elderly drivers are heavily invested in their "independence" and ignore obvious symptoms that militate against their continuing to drive. My father-in-law in his late seventies had macular degeneration, but somehow his doctor cleared him for driving. Eventually he sideswiped a parked car that he simply hadn't noticed, and he gave up. He was delighted to find that he actually saved money by not driving and didn't eventually feel that he'd lost his independence. As for the elderly in high office, I can think of one appalling person who should never be allowed to run again, but then he's been morally diseased all his life and cognitively deficient for at least a decade. Otherwise, there have been many competent politicians over 70.
@@hagbard72 Patently you have not caught up with the fact that most 70 year olds are still very much compos mentis? The retirement age is now 67 I believe, so are we to assume just a mere 3 years on, we have suddenly become decrepit? When you reach that venerable age, you will realise wisdom takes time to accumulate... Too many of the current politicians seem to have very little common sense, regardless of their number of years or lack thereof. Likewise with the young stockbrokers/bankers who nearly destroyed the entire banking system around 2008 ,selling financial products they did not understand, in comparison to the 60's and 70's when stockbrokers and bankers were all over 50, the system was stable and the country profitable.
@@sarahsnowe Accidents by youngsters are usually far more serious, and cause more fatalities than those caused by people over 70, so maybe those in their 20's should be taking annual driving and common sense tests until they're 30? ps I think the chap you mention has been cognitively deficient for much longer than a decade...
This is a very helpful conversation, loved it.
Great info by the learned Professor Claire! Please keep it up!
Good stuff for a brief overview. Could be it's own series really, the demand is obviously there 👍
So wonderful to hear real communication
Very informative, thank you.
I found this very helpful. Thanks!
This is very interesting, and Claire is really positive. I have worked across care support, helping people with learning disabilities but also dementia. I have an interest in diet and food effects on our health. Look at blue zone study, people that live active lives, but live in zones around the world, which provides these people with the right types of food, which reduces the risk of heart disease, dementia and their are many centenarians.
Thank you Jonathan. Can you keep your questions short & to the point.❤
So much wow!! I'd love to hear more about the brain gut axis.... if you were thinking of revisiting this topic.
Thank you both so much
A very interesting and highly knowledgeable professional. Unfortunately, she was interrupted too many times. It feels like Jonathan is trying to dumb everything down and also making it quite personal to his own concerns about dementia. I have noticed recently how often men interrupt women or talk over them. Hmmm. Just saying
before I stopped monosodium glutamate, yeast extract and other food additives, I was constantly sick with severe migraines, nerve pain in the neck nausea and ate sick amounts of painkillers I was sick for 25 years before I read on Facebook about all our poisons in the food, I stopped immediately and cook all the food myself today I am healthy and never have any headaches or migraines or nerve pains, I love life and do yoga 🧘♀️ every day and only eat what I cook myself 🤗🙌🏼💛💫
🎉
In common with other commentators: Jonathan, your efforts to simplify and clarify what the experts are saying are very welcome, but you need to work on your timing.
I must say the summary is quite brilliant!
Again a facinating pod cast - thankyou :)
Jonathon you may want to read some of the comments.
Great information, thank you. 🌟🕊
Thanks for all the great information you’ve put out to the world. Following the recommendations all of you have shared have improved my family’s health a ton. Would it be possible to do a podcast with Tim about diet and gut microbiome for people with autoimmune diseases like rheumatoid arthritis? Considering Tim was trained as a rheumatologist and a world leading expert for gut microbiome, it would be so helpful to listen to his takes on the subject. Thanks
I'll just add my stone to the edifice: I want to have more guest speaking time with fewer interruptions mid-sentence.
Wonderful session. Very useful and could benefit millions around the world!
It would have been easier to take in what the expert was explaining if the interviewer stopped wittering about his own experiences and family.
Excellent episode though we felt, on this occasion, Johnathan should have interjected less, and have allowed Claire more time to expand on the points she was making.
I agree about his interruptions, but he has mentioned many times before he is anxious about developing dementia. So I think it is an outward reflection of his anxiety.
Presenter needs to educate himself. Professor is v informative and fascinating to listen to, but the language used by presenter “head explode” stops me from forwarding to people it could help.
Superb programme and great information from Zoe.
Question: does anyone from ZOE read these comments or is it just us viewers/listeners commenting on each other?