Best Weekly Dose Of Primobolan (Side-Effect Free Anabolic?) Methenolone Deep-Dive
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- čas přidán 24. 07. 2024
- Bayer Rimobolan Medical Insert Translation: www.dropbox.com/scl/fi/h1wu9o...
Schering Oral Primobolan Medical Insert Review: • Schering Oral Primobol...
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TIMESTAMPS:
00:00 - Intro Teaser
00:22 - Analyzing Primobolan
00:43 - Medical Insert
05:22 - Methenolone Unique Characteristics
09:19 - Aromatase Enzyme Inhibition
10:45 - Methenolone Acetate & Enanthate Metabolites
12:41 - Detection Times
15:13 - Methenolone Studied In Human Conditions / Diseases
17:19 - Anemia Studies
21:16 - Stroke Rehabilitation In Hemiplegic Patients Study
22:32 - Methenolone And Liver Toxicity In Patients With Chronic Illness
24:05 - High Dose Primobolan Studies
31:01 - Summary Of Studies
32:36 - Kidney, Cardiac, And Brain Health
33:36 - Methenolone Enanthate Dosing
37:58 - Methenolone Acetate
39:45 - Closing Thoughts
#VigorousSteve #Primobolan #SteroidCycle - Sport
Bayer Rimobolan Medical Insert Translation: www.dropbox.com/scl/fi/h1wu9opdlgjtdvfmnszgo/Bayer_Rimobolan_Medical_Insert_Translation.pdf?rlkey=j0ssrd54mz34iiz83m274wcmy&dl=0
Citations:
Eales, L. et al. (May 1, 1972) Symptomatic Porphyria in a Case of Felty’s Syndrome. I. Clinical and Routine Biochemical Studies. Clinical Chemistry, 18(5):459-461. doi: 10.1093/clinchem/18.5.459
www.tesble.com/10.1093/clinchem/18.5.459
Frankle, M. et al. (1990) The effects of testosterone propionate and methenolone enanthate on the healing of humeral osteotomies in the Wistar rat. Journal of Investigative Surgery, 3(2):93-113. doi: 10.3109/08941939009140340
pubmed.ncbi.nlm.nih.gov/2285677/
Almustafa, M. et al. (1992) Effects of treatments by calcium and sex hormones on vertebral fracturing in osteoporosis. Quarterly Journal of Medicine, 83(300):283-94
pubmed.ncbi.nlm.nih.gov/1321457/
Fritzsche, D. et al. (1994) Effect of an anabolic steroid (Metenolon) on contractile performance of the chronically stimulated latissimus dorsi in sheep. European Journal of Cardio-Thoracic Surgery, 8(4):214-9. doi: 10.1016/1010-7940(94)90118-x
www.tesble.com/10.1016/1010-7940(94)90118-X
Fritzsche, D. et al. (April, 1995) Anabolic steroids (metenolone) improve muscle performance and hemodynamic characteristics in cardiomyoplasty. The Annals of Thoracic Surgery, 59(4):961-9; discussion 969-70. doi: 10.1016/0003-4975(94)01013-3
www.tesble.com/10.1016/0003-4975(94)01013-3
Shimodozono, M. et al. (September, 2010) Addition of an Anabolic Steroid to Strength Training Promotes Muscle Strength in the Nonparetic Lower Limb of Poststroke Hemiplegia Patients. International Journal of Neuroscience, 120(9):617-24. doi: 10.3109/00207454.2010.505352
www.wellesu.com/10.3109/00207454.2010.505352
Ikeda, S. et al. (August 25, 2013) The effect of anabolic steroid administration on passive stretching-induced expression of mechano-growth factor in skeletal muscle. Scientific World Journal, 2013:313605. doi: 10.1155/2013/313605
www.tesble.com/10.1155/2013/313605
Ozdemir, O. et al. (September, 2013) Side effect of metenolone enanthate on rats heart in puberty: morphometrical study. Experimental and Toxicologic Pathology, 65(6):745-50. doi: 10.1016/j.etp.2012.09.009
www.tesble.com/10.1016/j.etp.2012.09.009
Hussain, Z. et al. (August, 2016) Aspergillus niger-mediated biotransformation of methenolone enanthate, and immunomodulatory activity of its transformed products. Steroids, 112:68-73. doi: 10.1016/j.steroids.2016.04.007
www.tesble.com/10.1016/j.steroids.2016.04.007
El-Hawaz, R.F. et al. (June 18, 2018) In vitro mineral nutrition of Curcuma longa L. affects production of volatile compounds in rhizomes after transfer to the greenhouse. BMC Plant Biology, 18(1):122. doi: 10.1186/s12870-018-1345-y
www.tesble.com/10.1186/s12870-018-1345-y
Siddiqui, M. et al. (February 2020) Whole-cell fungal-mediated structural transformation of anabolic drug metenolone acetate into potent anti-inflammatory metabolites. Journal of Advanced Research, 24:69-78. doi: 10.1016/j.jare.2020.02.009
www.wellesu.com/10.1016/j.jare.2020.02.009
Kedzierski, J. et al. (August 1, 2023) Assessment of the inhibitory potential of anabolic steroids towards human AKR1D1 by computational methods and in vitro evaluation. Toxicology Letters, 384:1-13. doi: 10.1016/j.toxlet.2023.07.006
www.sciencedirect.com/science/article/abs/pii/S0378427423002205?via%3Dihub
Karim, A.A. et al. (February, 2024) Biotransformation of metenolone acetate and epiandrosterone by fungi and evaluation of resulting metabolites for aromatase inhibition. Steroids, 202:109345. doi: 10.1016/j.steroids.2023.109345
www.sciencedirect.com/science/article/abs/pii/S0039128X23001733?via%3Dihub
Clinical Trails:
Kaltwasser, J.P. et al. (February, 1988) Effect of androgens on the response to antithymocyte globulin in patients with aplastic anaemia. European Journal of Haematology, 40(2):111-8. doi: 10.1111/j.1600-0609.1988.tb00806.x
pubmed.ncbi.nlm.nih.gov/3278927/
Shimoda, K. et al. (May, 2007) The effect of anabolic steroids on anemia in myelofibrosis with myeloid metaplasia: retrospective analysis of 39 patients in Japan. International Journal of Hematology, 85(4):338-43. doi: 10.1532/IJH97.06135
www.tesble.com/10.1532/ijh97.06135
Okamoto, S. et al. (February 2011) Change in thigh muscle cross-sectional area through administration of an anabolic steroid during routine stroke rehabilitation in hemiplegic patients. American Journal of Physical Medicine & Rehabilitation, 90(2):106-11. doi: 10.1097/PHM.0b013e31820172bf
www.tesble.com/10.1097/phm.0b013e31820172bf
Human Studies:
Marquardt, G.H. et al. (December, 1964) Failure of non-17-alkylated anabolic steroids to produce abnormal liver function tests. The Journal of Clinical Endocrinology and Metabolism, 1334-6. doi: 10.1210/jcem-24-12-1334
www.wellesu.com/10.1210/jcem-24-12-1334
Olvey, D.N. et al. (August, 1965) Thyroxine-binding by the throxine-binding globulin as a measure of the anabolic activity of congeners of testosterone. Metabolism, 14:891-8. doi: 10.1016/0026-0495(65)90127-7
www.wellesu.com/10.1016/0026-0495(65)90127-7
West, H.F. et al. (November, 1965) Controlled trial of methenolone acetate in prednisolone-treated rheumatoid arthritis patients. Annals of the Rheumatic Diseases, 24(6):576-80. doi: 10.1136/ard.24.6.576
www.wellesu.com/10.1136/ard.24.6.576
Kennedy, B.J. et al. (1968) Effect of methenolone enanthate (NSC-64967) in advanced cancer of the breast. Cancer, 21(2):197-201. doi: 10.1002/1097-0142(196802)21:23.0.co;2-r
www.wellesu.com/10.1002/1097-0142(196802)21:2%3C197::aid-cncr2820210207%3E3.0.co;2-r
Palva, I.P. et al. (1972) Treatment of aplastic anaemia with methenolone. Acta Haematologica, 47(1):13-20. doi: 10.1159/000208491
www.wellesu.com/10.1159/000208491
Notter, G. et al. (1975) Treatment of disseminated carcinoma of the breast by metenolone enanthate. Acta Radiologica: Therapy, Physics, Biology, 14(6):545-51. doi: 10.3109/02841867509132696
www.tesble.com/10.3109/02841867509132696
Knobel, H. et al. (October 1975) Effect of an anabolic steroid (methenolone enanthate) on the intra- and extravasal albumin pool in liver cirrhosis. Zeitschrift für Gastroenterologie, 13(6):583-7
pubmed.ncbi.nlm.nih.gov/1224752/
Haak, H.L. et al. (1977) Acquired Aplastic Anaemia in Adults. Acta Haematologica, 58(6):339-52. doi: 10.1159/000207848
www.tesble.com/10.1159/000207848
Lockner, D. (1979) Treatment of refractory anemias with methenolone. Acta Medica Scandinavica, 205(1-2):97-101. doi: 10.1111/j.0954-6820.1979.tb06010.x
www.tesble.com/10.1111/j.0954-6820.1979.tb06010.x
Van Hengstum, M. et al. (March, 1979) Clinical course in 28 unselected patients with aplastic anaemia treated with anabolic steroids. British Journal of Haematology, 41(3):323-33. doi: 10.1111/j.1365-2141.1979.tb05865.x
www.tesble.com/10.1111/j.1365-2141.1979.tb05865.x
Najean, Y. et al. (October, 1979) Prognostic factors in acquired aplastic anemia. A study of 352 cases. The American Journal of Medicine, 67(4):564-71. doi: 10.1016/0002-9343(79)90226-2.
www.tesble.com/10.1016/0002-9343(79)90226-2
Garbrecht, M. et al. (March 27, 1981) Hyperlipoproteinaemia during additional methenolone administration in the treatment of metastasizing carcinoma of the breast. Deutsche Medizinische Wochenschrift, 106(13):400-3. doi: 10.1055/s-2008-1070325
www.tesble.com/10.1055/s-2008-1070325
Detection Times:
Fragkaki, A.G. et al. (May, 2015) Comparison of sulfo-conjugated and gluco-conjugated urinary metabolites for detection of methenolone misuse in doping control by LC-HRMS, GC-MS and GC-HRMS. Journal of Mass Spectrometry, 50(5):740-8. doi: 10.1002/jms.3583
www.wellesu.com/10.1002/jms.3583
Rzeppa, S. et al. (November-December, 2015) Analysis of anabolic androgenic steroids as sulfate conjugates using high performance liquid chromatography coupled to tandem mass spectrometry. Drug Testing and Analysis, 7(11-12):1030-9. doi: 10.1002/dta.1895
www.wellesu.com/10.1002/dta.1895
He, G. et al. (January, 2016) New long term metabolite in human urine for metenolone misuse by liquid chromatography quadrupole time-of-flight mass spectrometry. Steroids, 105:1-11. doi: 10.1016/j.steroids.2015.10.015
www.wellesu.com/10.1016/j.steroids.2015.10.015
Albertsdottir, A.D. et al. (April 12, 2021) Enabling the inclusion of non-hydrolysed sulfated long term anabolic steroid metabolites in a screening for doping substances by means of gas chromatography quadrupole time-of-flight mass spectrometry. Journal of Chromatography A, 1642:462039. doi: 10.1016/j.chroma.2021.462039
www.wellesu.com/10.1016/j.chroma.2021.462039
Clinical Trails:
Kaltwasser, J.P. et al. (February, 1988) Effect of androgens on the response to antithymocyte globulin in patients with aplastic anaemia. European Journal of Haematology, 40(2):111-8. doi: 10.1111/j.1600-0609.1988.tb00806.x
www.wellesu.com/10.1111/j.1600-0609.1988.tb00806.x
Shimoda, K. et al. (May, 2007) The effect of anabolic steroids on anemia in myelofibrosis with myeloid metaplasia: retrospective analysis of 39 patients in Japan. International Journal of Hematology, 85(4):338-43. doi: 10.1532/IJH97.06135
www.tesble.com/10.1532/ijh97.06135
Okamoto, S. et al. (February 2011) Change in thigh muscle cross-sectional area through administration of an anabolic steroid during routine stroke rehabilitation in hemiplegic patients. American Journal of Physical Medicine & Rehabilitation, 90(2):106-11. doi: 10.1097/PHM.0b013e31820172bf
www.tesble.com/10.1097/phm.0b013e31820172bf
man, this is like university material lol, but not even bachelor but master or even phd level.... Vigorous Steve to the pharmacology faculty !
Agreed our Dr Roid knows what he is talking about
You've never actually taken graduate courses have you lol
Love it when Steve releases videos back to back. I know it takes a lot of time to put all of this research together so thank you for your hard work 💪🏻🙌🏻
The best video i have seen about primobolan by far. So much information in a 40 min video,i usually spent weeks of research for a coumpound.This guy is amazing, he really loves what he is doing.Thank you ,thank you ,thank you.
Mate, being completely real, you're a real top g for sharing this knowledge with us, much aprrecation is being send from Poland, wish u the best❤
🙏🏽🙏🏽🙏🏽 citations, text summary, evidence and experience based guidelines and practical application. This is awesome!!! ❤
can't describe how much love I got for this channel and this guy. He simply covers EVERYTHING one would need to know about hormones.
Bro you are amazing,you do all the hard work for your followers.Thank you so much bro.
Nicely done VS.. Always bang on with another intelligent and descriptive video
Exactly the info I was looking for today haha. Thank you Steve 🙏🙏
1 day before i start my Benjamin button cycle man you are a treasure
Best source of information out there
No one else does it better Steve! Thanks for the information, top notch as always 💪💪
I followed your old primo protocol video for a first cycle for excellent results. Safe and effective. Thank you for the education and peace of mind as I did a first cycle. Wanna go again! Blast off :)
What video was it?
@@joshuam3903 hiya! Old video, don’t remember accurately…look for 1st cycle or ‘safer’ cycle :)
"I could pay you beer, or bratwurst, I'll bring it over in lederhosen if I have to, danke shoen!"
I know he's not a comedian, but that right there made me laugh out loud!
Such a wealth of information. I have to watch these videos several times to try to absorb even a fraction of the information.
I am really excited for Boldenon breakdown 👌 love form Germany 🇩🇪 Steve :)
Let's fkng go brothers!!! Primo is king!
Great video Mr. Uncle Vigorous 💥💪🏻💯...
Can see Steves Boulder Shoulders Splits & lines fanning Across, ready to Fire 🔥‼️ 💪🏻🥩🥩🥚🥚🍶🍶🍓🫐🥗🧇
Thanks for the info Steve. As of last week, I’m running 300T/250P. 😎 I have enough primo to last for 10 weeks at that dose but I may purchase a bit more if I’m feeling good 6 weeks in.
Where do you get it from ?
Maybe I missed this somewhere, but seems that Primo is good for controlling aromatization in a high BF% person?
Starting first cycle to cut fat: 200 test cyp a week (subq 3x a week). Every 2 weeks push test up 50 until estrogen sides to establish tolerance, then switch to 1:1 test primo up to that total. I am starting hypothyroid. Bloods every 6 weeks
Thanks Steve
Steve what can we do for the hair loss side effect.Do you think is a good idea to take minoxidine during my primo cycle?
Thanks buddy
I'm on 1400 teste and 1250 primo. Y'all can lob hate at me but this my stack and my bloods are great
Blood 🩸 in your urine?
Personally I would still be scared about things you can’t test for. But pros are pretty high too.
Dang broski, lean and mean!
Homebrew?
you dont need that much
Currently running 300testE/100Deca/400primoE and 2-4 iu of HGH daily, going on week 14 and bloodwork still looks good and I’m looking/feeling great. Having the Deca in there for my joints has been nice and I haven’t had any water retention due to the ratios that I am running. Love your videos Steve!
Was about to do this my self 375 test now and got 100npp in. Was gonna add 100 primo and work up. How’s your sex drive on this combo ? Through roof or not so much. Inwant a good sex drove stack
Recommend any good sites?
@@adamrochester1 I have 250iu of Hcg 3x - week in there as well. Forgot to put that in there, but my sex drive is through the roof. The wife and I haven’t been able to keep our hands off of each other. I’d recommend bumping the primo up higher to help with the AI effects. The ratios I have keeps my estrogen level in a perfect range.
@@user-fb8wh8cq1o do some research. Not putting any source info on here potentially getting Steve in trouble. Sorry.
How’s the cycle going bro?
whats better for acne sides like what is less likely to cause acne mastoron or primo or even var?
my primo is 200mg/ml haven't tested it but it supposed to have mct as the carrier oil but I don't get pip maybe it's under dosed but it definitely stronger than the previous brands I've tried
@vigorousSteve ,do you know of any channels that do pharmacology and endocrinology on females in the fitness industry?
How eq compare...and how how about hair eq vs primo
what ancillaries should you run?
It would be awesome if you did a video for the history on the medical applications of steroids. I am
Wish I had some primo...
Yet my doctor doesn't allow me 20mg test prop (I tolerate 50mg of it great). Even eating nutella on mass is forbidden by her. 😞
Next about drosta plz ❤
Do you lose beard hair on primo ?
I have a bigger problem, I cant find Rimobolan anywhere in Turkey!
Reasons to run methenolone acetate: 1. Anavar gives me bad psychological side effects. I believe someone said that it stimulates the sympathetic nervous system.
2. It was cheap 3. There is an independent lab test report available saying that it is real. 4. They were out of enanthate. 5. No Primo Pinning. It's not THAT bad. But it sucks.
I would greatly appreciate a bit more info on dosing the oral. From what i have read, 100mg/day orally is supposed to be roughly equivalent to 400mg/week injected. Can you confirm or deny this rumour? Great video, liked and subscribed.
I wonder about the oral dosage too
Anyone here ever had gallbladder issues, digestion issues and or Liver toxicity while on Primo?
I have a Japanese Bayer Primobolan acetate insert if you need one. Not interpreted though.
Yes please email it over buddy!
Hoping that adding minoxidil with microneedling on top of my current finasteride dose will curb any hair loss, may end up adding slight additional finasteride weekly as well
What about liquid oral primo?
5:45 He! I can translate it for you. If you have the publication
What about 100mg trt a week with 100mg NPP plus 100mg primo? I like to microdose everything and people think I’m juiced to the gills. That’s what I’m always on and I hold a shit ton of muscle
Before that I was on 140mg trt and 3cc HCG a week for 7 years, when I lowered the test and added the other two I felt better than ever and my muscles grew. Didn’t feel good on the 140mg trt only
Does primo hair loss go away after primo cycle is done? Or does the hair stay gone, or is it time and dosed dependent? Like if someone did 500mg test 500mg primo for only 3 months and came off would the likely hood of the hair coming back be high?
Depends if you're pre disposed. If you are, badluck :(
100mg prime ace oral for 30 days pre contest is my recommended dose.
This popped up as 'related' in a search for 'increasing breast size.'
Can I run 500 test - 600 primo?
I could translate you English studies 👋🏿
Greetings from Germany 🫶🏾
Wait, 1gram isnt the standard nowadays?
Algo!
Steve should do eq vs mast for us dudes too cheap to run a full gram of primo 😂
Haven't seen the video yet, but My guess is as much your muscles can soak up! 2500mg 1:1 with Test E FTW!!!!!!!!
Love primo
My 2 cent from a Turk
I ran 800mg sus, 800mg primo and 400mg npp for 16 weeks in the off season. My egfr was at the bottom of the reference range and my creatanine was slightly above the reference range. Last cycle I ran 600mg test and 300 deca and bloods were fine. Not sure if it was the primo or just a combo of everything hammering my kidneys but I jumped off straight away. E2 was also in the gutter so it seems like for me I need to run test 2:1 with primo not 1:1 as steve has suggested in other videos
How’s ya sex drive on that
Sex drive surprisingly was still quite high. Problem was not getting proper erections, even taking 20mg of ciallis wouldn't get my dick to a full sized erection
@adamrochester1 not too bad surprisingly considering how low my e2 and shbg was. Only issue was not being able to get a maximum erection I was about 1cm down on size and girth lol even when taking 20mg ciallis
@@elcucuy8486 try just taking the Npp out I reckon or was problem
Fixed when you did 600 test 300’deca ?
Unless you ran Rimobolan then it’s not the same thing. Primo cannot be copied no matter how good the underground lab is.
“Side effect free” yet the only roid that’s ever made shed hair like crazy 😂 wish I could run it without that happening.. still have a full 200mg/ml vial
I’ll buy it off ya
I'm already bald... 🤔
Use ru58841
I'll pay what piger offers. Plus a dollar
I volunteer myself as a hair loss experiment. Please send to my P.O. Box and I will let you know whether or not I still have hair.
LeeLu Dallas Primo Multipass
Arnold took two shot of primo a week and his kidneys are still fine 😂
Dang Steve, you ramble.
I wish trt clinics sold it.
It's an anabolic steroid lol...
So what. My clinic sells eq anavar and deca.@@zachb86
Problem is they prescribe at low dosages. I got no noticable gains on 100 mg deca.
The reason of running oral Primo is because if it`s real Primo is a lot safer for lipids and liver. Anavar just ruined lipids for most of the people, raised ALT, AST because is 17α-Alkylated anabolic steroid. So thats quite strange that you asking this obvious question.
Can you go more into depth with Turkesterone? I hear its not effective but then i hear it is
It's not. Go another route
No noticeable effect for me. Everything else that source had was pretty good quality, so, it was probably good stuff.
If you could ever find real (full) Primo to begin with.
All they’re buying these days are all counterfeit shit, dianabol has been phased out since 1982 from CIBA, and Primobolan and Testoviron also has been phased out from BAYER long time ago 🤷♂️
Primo needs 800 MG and up
I dont like ling vidéo. How much for safe cycle and trt ?