Hypersensitivity and Allergic Reaction Types Made Easy [Simple Rhyme for Type 1, 2, 3, and 4]

Do you want an easy way to remember the different types of hypersensitivity reactions? Use this simple rhyme to remember hypersensitivity reaction types 1-4.
The immune system has 4 main types of hypersensitivity reactions: Type 1, Type 2, Type 3, and Type 4. The pathophysiology is unique for each one.
A Type 1 hypersensitivity reaction is a typical allergic reaction. It uses IgE antibodies produced by B cells against an allergen. This causes histamine release from mast cells and basophils to cause an allergic reaction. Examples include anaphylaxis, food allergies, medication allergies, and allergic rhinitis.
A Type 2 hypersensitivity reaction involves IgG and IgM autoantibodies that attack the host. Examples include autoimmune hemolytic anemia, Goodpasture Syndrome, and Myasthenia Gravis.
A Type 3 hypersensitivity reaction involves IgG antigen-antibody immune complexes that deposit in the joints, kidneys, and blood vessels. The immune complexes activate the complement system leading to inflammation, arthritis, glomerulonephritis, and vasculitis. Examples include lupus and serum sickness.
A Type 4 hypersensitivity reaction involves T cells rather than antibodies. The classic example is poison ivy. Antigen presenting cells such as macrophages present the antigen to helper T cells. The CD4 helper T cells then become memory T cells and produce an immune response the next time they are presented the antigen.
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[@mavrakhan8254]

Always struggled with hypersensitivity reactions. Not anymore 😊 thank you

[@ezmed]

Awesome! 👏 Glad this video could help!

[@daughteroftheking5875]

This was super help…Thank you so much!!!

[@ezmed]

You're welcome! 👍

[@saramaria-]

MSN student here, thank you for this

[@ezmed]

No problem! Good luck to you!

[@androidplus.1]

Bravo ♥

[@ezmed]

Thank you! 🙏🏻