Why Would My Sex Hormone Binding Globulin Be High?

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  • čas přidán 25. 03. 2020
  • Why would my sex hormone-binding globulin be high? not mine but maybe you're asking a question why is your sex hormone-binding globulin elevated what you can do about it. What are some of the driving forces behind that elevated section 1 binding? it might be a male with this or a female with this, in any case I'm going to discuss some of the driving factors behind sex hormone binding globulin secretion and production in your body. If this is something that interests you keep watching we're gonna get into the details so why would my sex when I'm buying a globulin be high if you're asking this question we're going to get into it in a second but first I wanted to explain just briefly about sex moment binding globulin so this is a protein that is produced in the liver and has different signals from the body that will make you produce more or less of this hormone its main function is to carry other hormones to make your body produce this protein but its main function of this protein as to carry different hormones throughout your body so that they don't immediately bind to receptors it can be more evenly distributed throughout your body so mainly the sex hormone binding globulin binds things like estrogens and testosterones there's various types of estrogen there's a e1 e2 e3 and there's different metabolites of those as well that probably does carry and same thing with testosterone there's dihydrotestosterone and other metabolites of testosterone that the sex hormone binding globulin probably does control some of that so that it's not binding to the receptors in the case that it would stimulate the receptors so basically so what are the things that can increase sex hormone binding globulin so there's a few the most notably and most commonly referenced is estrogen so we know this because females have more sex hormone binding globulin than males and we also know that birth control can be used to to raise sex hormone binding globulin so within women with PCOS for instance will sometimes get put on birth control and that will raise their sectional binding globulin it's not an absolute answer but it can help in the interim we also know when you're on birth control your testosterone females will have a lower free testosterone and sometimes that will because it lowers the raises a section on binding globulin it lowers the free testosterone and basically for for males and females you have total testosterone antal estrogen but we'll just use stas drone because it's a little simpler to think about it so yup total testosterone which includes the amount that's bound actually them out that's unbound or free and then the rest of it is is bound up so you have a small part of your total testosterone that is free and available or bioavailable and a big chunk of that is being bound up by the sex hormone binding globulin so when you have an issue with low testosterone symptoms part of the issue is instead of having your small fraction you may have much smaller fraction that is free or bioavailable so one of the things so estrogen comes in a lot of different forms and the abnormalities of this for males can happen when you have more fat mass than you do muscle mass that causes the adipocytes are where that's what the cells of the fat tissue are called and they tend to have more of these aromatisse enzymes and aroma or excuse me aroma taste enzymes basically take the testosterone and turn it into estrogen as a result that gets circulated back up to the liver causes the liver to make more of this sex hormone binding globulin there's also the issue with xenoestrogens or environmental estrogens things like plastics are most commonly referenced but there's other chemicals that are known as xenoestrogens and basically they can stimulate estrogen receptors in a similar way as the actual estrogens do and as a result is the theoretical I don't have any research on this so I'll just say it's theoretical at this point that those can also stimulate the receptors in the liver to produce more of this sexual and binding globulin things like soy products or soy isoflavones are also weak estrogen we kept estrogenic effects and potentially these could also bind to the same sites in the liver and produce so more this section one binding module think the salt soy thing with estrogen can be overblown but you know if you have this problem it may be something to consider. functional medicine practitioner
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Komentáře • 150

  • @Starchaser63
    @Starchaser63 Před 6 měsíci +2

    Boron is noted for lowering SHBG. Also Proviron ( mesterolone ) is effective for lowering SHBG and restoring Testosterone levels in men with symptoms of low testosterone. Proviron is legal and available here in UK to buy for personal use and in most countries but not in USA at the moment...

    • @jordixboy
      @jordixboy Před 3 měsíci

      Boron will increase it for 1-2 weeks, later it will have the opposite effect and increase it alongside estrogen... This is well-known and supported in scientific literature.

    • @Starchaser63
      @Starchaser63 Před 3 měsíci

      @@jordixboy it depends on the dose..various studies using various doses makes a difference...high doses of 10 mg works less effectively at some stage, however a lower off and on dose of 3 mg had a much long term effect...individuals differ.. Best is to see how each person responds .... higher dose usually backfires.. most studies used 10 mg Boron which ultimately has less effect....

  • @boplop5406
    @boplop5406 Před 3 lety +5

    Btw thyroid meds and hyperthyroidism can increase shbg :).
    Your video was very informative

    • @swintegrative
      @swintegrative  Před 3 lety +2

      Yes, true and this makes sense as it fits with the metabolic profile of being in a fasted low insulin state. So many things alter SHBG.

  • @MrX-rr8cw
    @MrX-rr8cw Před 3 lety +1

    Job well done. Question --- since it is produced in the liver. Would focusing on clearing out the liver/liver detox; glutathione and/or NAC be a good place to begin as well? Yes, cleaning up the diet: Gluten/Wheat/Dairy/Soy/Sugar --- of course. My wife has a SHBG of 169.0 and testosterone, serum at 15, Free Testosterone (direct) at 1.4. Her Doctor says the Test values are below normal range and clearing up the liver/diet is a good place to begin. Thank you for your help.

    • @swintegrative
      @swintegrative  Před 3 lety +1

      Hi Mr X, yes these things will not hurt and potentially help. You can also recheck in a non-fasting state.

    • @MrX-rr8cw
      @MrX-rr8cw Před 3 lety

      @@swintegrative Thank you for your response.

  • @almarco2341
    @almarco2341 Před rokem +1

    Good morning Doctor, thank you for the informative video. Beyond what level (nmol/L) would you begin to be concerned about SHBG blood levels please?

    • @swintegrative
      @swintegrative  Před rokem

      It all depends what you are optimizing for SHBG in and of itself it not something to be worried about it is in the context of your health symptoms and problems that it is relevant.

  • @Mrsjonnelle
    @Mrsjonnelle Před 4 lety

    Thank you sir.

  • @wanderlusttom
    @wanderlusttom Před rokem +2

    Great video. You should buy a microphone, will make them even better!

  • @michaelhampson749
    @michaelhampson749 Před 2 lety +1

    Hello thank you for the video. My labs recently were
    Male 30y/o weight 165lbs. Height 5’7”. Body fat 10 percent lifting 4 days per week compound cardio 2 times caloric surplus by 100 a day
    Total t 704
    Free T direct 7.7 low
    E2 29.1

    • @michaelhampson749
      @michaelhampson749 Před 2 lety +2

      Every lab since I have been in my twenties has got me at low free t and normal high total t

    • @swintegrative
      @swintegrative  Před 2 lety +1

      Growth hormone?

    • @rik9833
      @rik9833 Před 6 měsíci +1

      ​​@@swintegrative Sucks for this to be the only answer. Why is it th guys who take of themselves and family are targeted with something outside of their control. Naturally high shbg plus extremely low free t with normal total t, at age 22, I lift 6 days a week. Feels like I've been cursed. One thing I have noticed that is recurring is that 95 percent of guys with these symptoms are physical active.

  • @archanasuresh2846
    @archanasuresh2846 Před 4 měsíci +1

    subscribed from INDIA ❤

  • @BigSoul29
    @BigSoul29 Před 7 měsíci +2

    Mt SHGB is 198... I've been plant -based for the past 10 years.

  • @judsonjman26
    @judsonjman26 Před 2 lety +3

    Thanks for the video! I just got an at home Testosterone test done and my test levels where normal, but my SHBG was a bit high. I've been in a modest caloric deficit for roughly 14 months losing about 1.5 lbs per month and I've done so via intermittent fasting and tracking my calories. Sounds like there's a decent chance this is the reason for my slightly higher SHBG. Going to go off intermittent fasting and see how I feel and go get retested.

    • @swintegrative
      @swintegrative  Před 2 lety

      Best of luck! Thanks for sharing and I think that sounds correct.

  • @mikebrown965
    @mikebrown965 Před 2 lety +1

    Super active 40 year old male. Healthy diet. Lean body mass:
    SHBG- 117nmolL
    Total testosterone- 151.4ng/dl
    Free testosterone 2.2 pg/dl
    Dihydrotestosterine 4 ng/dl
    LH 2.9
    Estrodiol

    • @swintegrative
      @swintegrative  Před 2 lety +1

      Hi Mike, check other estrogen tests… estradiol LC/MS and total estrogens. Also growth hormone and low carb low calorie diet may contribute.

    • @RaginCajunDroid
      @RaginCajunDroid Před rokem +1

      Keto diet?

  • @DL-rl9bd
    @DL-rl9bd Před 2 lety +2

    I cannot find any information on men with: low-normal SHGB/low-normal total testosterone/elevated (just over the lab range) of free testosterone.
    What does this mean?
    My A1C was high-normal (just before “pre-diabetic”. I have read insulin resistance can lower SHBG, but I’m not even pre-diabetic, yet.

    • @swintegrative
      @swintegrative  Před 2 lety +2

      You can still have high insulin levels and this would be the first place to look as it is the most common.

    • @DL-rl9bd
      @DL-rl9bd Před 2 lety

      @@swintegrative the A1C was 5.5 so that’s definitely high while not yet being type 2 diabetic

  • @fartmonster6940
    @fartmonster6940 Před 3 lety +1

    My shbg runs high, free testosterone was low. I recently switched from testosterone cream to injections, due to fear of the cream getting on my children. My estradiol runs on the low side, since I am 45 and perimenopausal. I am on a low dose estradiol patch and 50 mg compounded estrogen, due to very low estradiol levels ( night sweats, fatigue, achy legs, etc). Testing still indicates lower in the range, but within the range estradiol. I am also on a combination of levothyroxine and sublingual Np thyroid. Two questions. 1- could the thyroid medication or transdermal estrogen be driving shbg up, despite my levels being in normal ranges? ( I don’t have a thyroid). 2- it could be a coincidence, but I am noticing that the two days after I inject 15 mg of testosterone cyprionate, I’m irritable and a little sad. Could it be the testosterone? Could taking testosterone cause a temporary increase in shbg, causing these moods, or is it just estradiol that does it? I’m perimenopausal, do I get moody, but it is just weird that it’s the couple days after I inject the testosterone.

    • @swintegrative
      @swintegrative  Před 3 lety

      Hi Katie Bugs Room. Here are a couple things to keep in mind, estradiol is the main estrogen that should be tested. The ranges for this vary widely through your monthly cycle. If you are not checking at the same time of the your cycle each month, the results don't mean much. The issues mostly like is coming from too much estradiol not too little. Estrogen increase SHBG. Testosterone increases estradiol. Typically women in perimenopause have estrogen dominance already. It is possible that you don't but you might be getting too much now. Hope that makes sense.

    • @Blkout2k1
      @Blkout2k1 Před rokem +1

      Hard to take anyone serious with a name like that.

  • @meltingpot1381
    @meltingpot1381 Před rokem

    dd a blood test at 9:00 am . Im 28 y old . Total testosterone higher than norms : 29,5 nmol/L ( normal range 8.64-29) . SHBG extremly high : 84,5 nmol/L (normal range:18,3-54,1) Free testosterone "in the frontiers of low" : 34,9 (normal range: 35-93). Why SHBG are so high ? i mean difference of more than 30 nmol/L makes me concerned ...I measure around 176 cm , 68 kg , muscular wide but with no fat ,and i look way masculine ( i do not have a full beard by the way , but my body shape , face are way masculine) ..
    And also in the blood test icteria was positive (theres like levels of icteria like +or ++ or +++ i believe by writing " positive" means +
    Noticed that at 28 years old my larynx "developped and become prominent" , while the length of my neck increased 1 or 2 cm ( before 27 i was more in the 174 cm with a very short neck ) With the neck thing and the larynx who became prominent i mean can be related to thyroid?

  • @rob2878
    @rob2878 Před 2 lety +2

    shbg - 120 nmol/l --- abnormally high
    free T - 80.9 pg/ml --- normal range
    3 total T results (all within 6 weeks - natural) - 1492, 1500 and 1165 ng/dl - abnormally high
    My blood panel showed all my other hormone results to be within normal range or just slightly on the high end, but nothing abnormal.
    Anyone ever experience these similar levels and if so what did you do to get everything back in normal range?

    • @swintegrative
      @swintegrative  Před 2 lety +2

      estradiol is likely high d/t high testosterone levels. This will then driving up shbg. If u are not taking something to raise your testosterone you should have an evaluation with a doctor.

    • @rob2878
      @rob2878 Před 2 lety

      @@swintegrative Thanks for the response! Estradiol was at 43 pg/ml which i believe is a bit on the high end, but nothing abnormal.
      The endocrinologist suggested there was nothing i could do about it and that i would be fine. I respectfully disagree with his diagnosis so i am going to get a second opinion.

    • @swintegrative
      @swintegrative  Před 2 lety +3

      @@rob2878 not a bad idea but I would not be too concerned either. The only concern with high testosterone is that it is coming from testicular cancer .once you rule this out, it seems fine. good luck

  • @beemrmem3
    @beemrmem3 Před 3 lety +1

    Hi. My total test is 854ng/dl. Free T is 16.3pg/ml , SHBG 54.3 Nmol/l and estradiol 43 pg/ml(slightly higher than normal range). I went to the doctor for mild to moderate. ED. He thinks it’s just psychological and gave me a Cialis Rx. Do you think my slightly higher than normal SHBG and estradiol could be causing it? I was thinking of taking a mild aromatase inhibitor to see if it will lower my estradiol and SHBG. He thinks I’m fine because my testosterone is high

    • @swintegrative
      @swintegrative  Před 3 lety +1

      Hello Logan! A free T of 16.3 pg/ml is decent. High or high normal estradiol can have a negative effect on erectile function. It won't do this to everyone though. It may be worth while to have a closer look look at the estradiol and check the MS/LC estradiol. This is a more accurate test.

  • @2001beril
    @2001beril Před rokem +1

    Hi, after 5 months of using birth control, my SHBG levels are very high (260 ish). How long does it take to get back to normal limits after quitting the bc pills?

  • @tomdaniels6709
    @tomdaniels6709 Před 9 měsíci +1

    If you do TRT what do you advice for this than?

  • @quantabyte
    @quantabyte Před 3 měsíci +1

    I found one CZcams video of a fellow saying he lowered his iron saturation and his SHBG decreased. I’m in same boat with high iron sat and high SHBG. Could high iron saturation raise SHBG?

  • @NightLetterLondon
    @NightLetterLondon Před rokem +2

    i went on to TRT due to low T symptoms. and, to hopefully lower my SHBG. after 7 weeks of 100mg/week of cypionate my total T has gone up significantly, but my free T is so low that it is not testable at all on a blood draw (result is NC). my SHBG is well over 200. my estradoil is not high, but i have gyno.. i'm frustrated and a little worried. i'm fit, healthy, gym training.. and have been all my life. would appreciate some advice..

    • @pauldrolone6912
      @pauldrolone6912 Před rokem

      I'm not a doctor but a small dose of proviron or masteron enanthate would be a great addition to your TRT. Good luck getting a doctor to prescribe you any.

    • @swintegrative
      @swintegrative  Před 11 měsíci +1

      Check growth hormone?

  • @Pete4875
    @Pete4875 Před rokem +1

    Great Video! 68years old T.729 But B.Globulin 80 nmol/l and Bioavailable 87.6 ng/dl. I think I was on the second day of a 5 day fast when taking. Any thoughts?

    • @swintegrative
      @swintegrative  Před rokem

      Thanks for sharing! Well the free would be higher if you were not fasting.

  • @amina-xe7wl
    @amina-xe7wl Před 3 lety +1

    Hi,
    Would you be able to help me. I am 26’year old female. All my blood work came back as normal apart from
    SHBG. What could this mean? I’m not on any medication or have any health issues. I was also told this is the reason as to why I have irregular period too

    • @swintegrative
      @swintegrative  Před 3 lety +1

      Hi Amina, it is hard to know what you mean by "all my blood work" different doctors test for different things. Insulin resistance and high insulin is a very common cause for high SHBG. You need to find a doctor that can look a little deeper than the surface level, like a functional medicine doctor.

  • @greeningout26
    @greeningout26 Před 11 měsíci

    hi! i’m a 20 year old female and just had a fasting blood test done. my shbg was 190.30 nmol/L and my t3 was slightly high at 4.1 pg/mL. i was wondering if these had any correlation? thanks!

  • @JamieVegas
    @JamieVegas Před 6 měsíci

    More importantly, why would it be LOW? And how does one fix it?

  • @nikunjpaturi2006
    @nikunjpaturi2006 Před 4 měsíci

    Hello Doctor I am from India.
    My name is Nikunj and I am 14 year old boy. I am suffering, (*sorry) having T1D (Type 1 Diabeties) but actually having a good control on sugar levels as I am taking Insulin and monitering blood sugar levels. But I have other problem in my body, I am growing hair all over my body, like arm hair, chest hair, hairy legs, and unwanted hair growth of forehead and surface of nose. None of my friends have this issue and I think I am having high testesterone. I went to dermatologist and she prescribed me two tests. One is testesterone serum and other one is the thing you are talking (SBHG). The only doubt now I have is, Is it anything connected to T1D? If I take medications for controlling Sbhg or testesterone levels, will it affect my diabeties? Or even any other hormones in my body? If yes, please inform doctor 😊
    Subscribed your channel

  • @samanthasantaw4915
    @samanthasantaw4915 Před 3 lety +1

    Hi,
    I'm confused as to why my SHBG is 173, my total testosterone is 53. I'm a 30 year old female. I have read that it usually isnt like this. I've never had birth control.
    Any insight on what might be going on? My progesterone to estrogen ratio is 45.16.

    • @swintegrative
      @swintegrative  Před 3 lety

      Hi Samantha, high estrogen is often a cause but bc estrogen is changing all the time (with your cycles), you have to check at different times of the month. Also you have to check when you are non-fasting as the level will be lower.

    • @swintegrative
      @swintegrative  Před 3 lety

      Also 53 total testosterone is not that high.

  • @iofferyoueternity
    @iofferyoueternity Před 3 lety +1

    47yo, SHBG is 75, total test is 798, NO free t, no insulin resistance, low estrogen, normal estradial, can't lose weight but don't have much, not diabetic, mild ed, runner and active, no one knows what's going on!

  • @michaelkmiec5842
    @michaelkmiec5842 Před 11 měsíci +1

    I have had every single symptom for about 2 years now I am wondering why my SHBG is at 120. I’m a 25 year old male.

    • @levishepard3696
      @levishepard3696 Před 2 měsíci

      Mine was just tested at 110. I’m 27. Iv felt like shit for like a year. Not sure what i did.

  • @piusnevitt9711
    @piusnevitt9711 Před rokem

    Watched a lot of these videos and no one as of yet tells you the range. I got three blood test, dates 4/6/23 SHBG 68.9 - Range 19.3-76.4 One lab. Second lab: 4/20/23 SHBG 57.2- *Range 22-77; Third lab: 5/15/23 69.5- *Range 21.4-67.8. So the third lab shows out of range according to the range all three were out of range if I used the thrird lab range. Anyone know what the true range is?

    • @swintegrative
      @swintegrative  Před rokem

      Reference ranges are based on the sample population averages so they will vary with said sample size. That’s why when you reach the high end or low end of a reference range, even if within the range, it’s good to look at it more carefully.

  • @alisyed9584
    @alisyed9584 Před 11 měsíci +2

    Hey there, I’ve got a bit of a weird one personally. 24M, my SHBG is 10, my thyroid, liver, kidney, lipid are perfect. I am lean enough for ab visibility. Muscle mass high, never take anything exogenous. test is in the low range of normal 12nmol/L. oestradiol is above average 132 pmol/L. my endo is saying my shbg is genetic. is this true or do I have something to be worried about?

    • @swintegrative
      @swintegrative  Před 11 měsíci

      I know there are SHBG snps but not something I have studied much. So it could be genetic.

    • @alisyed9584
      @alisyed9584 Před 11 měsíci +1

      @@swintegrative okay fair enough. unsure if you’d find this interesting but I got a bit fed up of my hormonal inbalance and started taking an aromatase inhibitor two weeks ago. received my results today and my testosterone has near tripled, oestradiol halved, prolactin halved, LDL decreased and triglycerides also decreased. I call that a successful self diagnoses (albeit a very very meticulously researched one)

  • @julianbrown7976
    @julianbrown7976 Před 11 měsíci +1

    What about iron overload ? I was wondering whether very high SHBG might be a safety mechanism when the red blood count is already too high and the body decides to shut down free T because testosterone increases haemoglobin on its own account. Hemachromatosis is a silent killer after all.

    • @swintegrative
      @swintegrative  Před 11 měsíci

      Not that I know of and I don’t think SHBG binds iron. It binds testosterone but the increase in RBC from testosterone is not the same problem of high iron in hemochromatosis. They are different problems and mechanisms.

    • @julianbrown7976
      @julianbrown7976 Před 11 měsíci

      @@swintegrative I meant: when there is chronic iron overload and there is a risk of RBC getting dangerously high, the body might increases SHBG production (by some currently unknown mechanism) in order to get low FT so that there is no further stimulation of RBC production from that source.
      I say this because as an otherwise fit and healthy 63, I have extremely high TT (32 nmol) and SHBG (120 nmol), high ferritin saturation and very low (symptomatic) FT.

  • @7TheWhiteWolf
    @7TheWhiteWolf Před 10 měsíci

    I’ve heard Matcha/Green Tea drastically raises SHBG. Is this true?

  • @johnc2743
    @johnc2743 Před 3 lety

    Hi
    My testosterone was high at 42nmol/l and SHBG high at 79nmol/l so it worked out my free testosterone was in normal range. Should I worry or is there anything I can do 🤷‍♂️?

    • @swintegrative
      @swintegrative  Před 3 lety +1

      Hi John C, total testosterone of 756 ng/dl seems normal to me. I would not worry but if you have low T symptoms, you might want to look into it more. You do have to check the SHBG in fed and fasting states bc it will change with this.

  • @zuzuki8422
    @zuzuki8422 Před 3 lety +1

    Hi. I have very high SHBG and very low progesterone. Does it mean I can have PCOS? Also suffer from hairloss. Might caused by this hormonal imbalance? Thank you

    • @swintegrative
      @swintegrative  Před 3 lety +1

      Hi Zuzana usually with PCOS there is low SHBG. Hair loss can be from high androgens but not low progesterone or high SHBG.

    • @zuzuki8422
      @zuzuki8422 Před 3 lety

      @@swintegrative thank you

  • @richguev
    @richguev Před 7 měsíci

    What are the symptoms?

  • @jimmijimmi7183
    @jimmijimmi7183 Před rokem

    Hello, I wanted to know if HIGH CORTISOL =
    HIGH SHBG, LOW CORTISOL = LOW SHBG?

  • @lil.k.i.2_fie749
    @lil.k.i.2_fie749 Před rokem +1

    I am 18 year old male total testerone 970 I play basketball what should free T and SHBG be and estradiol?

  • @gif24gt60
    @gif24gt60 Před 3 lety +2

    Can non alcoholic fatty liver cause high SHBG? If so, how do you effectively reduce fat on the liver?

    • @swintegrative
      @swintegrative  Před 3 lety +4

      Yes it can. There is a video on fatty liver and liver enzymes coming up.

    • @gif24gt60
      @gif24gt60 Před 3 lety +3

      @@swintegrative looking forward to it. Everytime I ask a traditional primary care Dr. How to eliminated accumulated fat on the liver as indicated by ultrasound, I get a blank stare. Well, among a lot of things.

  • @ElRevelator
    @ElRevelator Před 8 měsíci

    What if SHBG is too low? Mine is under 10, and it required me to do ED injections.

  • @simplysurreal6139
    @simplysurreal6139 Před rokem +1

    Total Testosterone - 1139.0
    Free Testosterone- 15.68
    SHBG- 70.3 (High)
    I’ve been vegan for 8 years, I’ve done intermittent fasting now for 2 years now. I’m 6’5” about 240lb. I workout regularly.
    Is there anyway to low my SHBH?

  • @zoz3692
    @zoz3692 Před rokem +1

    age 23
    SHBG:77.9 nmol/l
    Albumin 5.1 g/dl
    TT:580 ng/dl
    Estradiol: 23 pg/ml
    LH 5.8 miu/ml
    prolactin 11.4 ng/ml
    i believe i have this since puberty
    what are my options i live healthy life style

    • @rik9833
      @rik9833 Před 6 měsíci

      How do you feel a year later? Are the numbers about the same?

  • @mixshorty222
    @mixshorty222 Před rokem

    I found out I have very high SHBG I also have PMDD so I think that maybe why. I also have low progesterone and estrogen. What do u suggest would be a good way to fix this?

    • @swintegrative
      @swintegrative  Před 11 měsíci

      Could be usually estrogen and SHBG run opposite so u might double check that. It’s different at different times of cycle

  • @linnawatley
    @linnawatley Před 3 lety +1

    What would it mean if both my shbg and my testosterone is high? I did start birth control for regulation of hormones/period but I always see that the relationship for the two is that one is high and one is low

    • @swintegrative
      @swintegrative  Před 3 lety +2

      Hi Yolinna, high estrogen/ estradiol is a common cause of high SHBG in females. I'm not sure how your BCT will affect affect SHBG. It will reduce your bodies estradiol and therefore reduce SHBG. Because some BCT contain estrogen, it will likely increase SHBG more. There are too many variables to know for sure without and in depth evaluation.

    • @linnawatley
      @linnawatley Před 3 lety +1

      @@swintegrative thanks it was worth a try lol I know our bodies are complicated

  • @brennan1895
    @brennan1895 Před 4 lety

    hey im 34/male, gym 3-4 times a week, higher protein diet, moderate fats and carbs and eat at maintenance calories and im not to sure why my shbg is so high love to hear your thoughts thanks in advance , my blood results are
    thyroid fuction :
    TSH - 4.2 miu/l
    free thyroxine - 18.100 pmol/l
    testosterone - 27.4 nmol/l
    free test - 0.308 nmol/l
    SHBG - 82.8 nmol/l ***
    oestradiol - 65.9 pmol/l

    • @swintegrative
      @swintegrative  Před 4 lety

      Yeah that SHBG seems really high but I am use to different units. Have you had an estradiol done with MS/liquid chromatography? This estrogen seems normal but would be curious what the more accurate test shows. Was the test done fasting?

    • @Memic86
      @Memic86 Před 2 lety

      @@swintegrative will fasting cause it to be high? I did my testosterone blood test when i was fasting

    • @swintegrative
      @swintegrative  Před 2 lety

      @@Memic86 yes that can make SHBG higher than it would be in a fed state

    • @Memic86
      @Memic86 Před 2 lety

      @@swintegrative i appreciate the quick reply. What about estradiol? Both estradiol and shbg was slightly high. Estradiol at 44 Shbg at 56

    • @swintegrative
      @swintegrative  Před 2 lety

      @@Memic86 estradiol raises SHBG too

  • @osvaldovillarreal8750

    What is normal? What is high?

  • @tinamt221
    @tinamt221 Před 4 lety

    I am a 42yo female and my SHBG is high. So is androstenedione. Can you help me understand why? Does it mean my testosterone is high or low?

    • @tinamt221
      @tinamt221 Před 4 lety

      SHBG is 138 and the range is 30-135. Androstenedione is .915 and the range is .19-.82

    • @swintegrative
      @swintegrative  Před 4 lety

      Hi Tina,
      It sounds more like your estrogen is high. Androstenedione is converted into either testosterone or estrogen. Since you have high SHBG I would predict higher estrogen levels. As for the question why is harder to answer but the production of androstenedione comes from adrenal glands and the ovarian tissue. Do you have a direct measurement for estradiol or testosterone?

  • @kollywoodztv6690
    @kollywoodztv6690 Před rokem +1

    My total testosterone is 524ng/dl
    Free t is 1.1 ng/dl
    Estrogen is normal
    I have low t symptoms
    Is high shbg the reason?
    If so how to bring it normal

    • @swintegrative
      @swintegrative  Před rokem +1

      Low free T is caused by high SHBG. There is not one thing you have lo look at the things mentioned in the videos

  • @user-vv6cb9vo7d
    @user-vv6cb9vo7d Před rokem +2

    What if you have high SHBG(close to 200) and you're diagnosed insulin resistant?

    • @swintegrative
      @swintegrative  Před rokem +1

      You must be a female and producing a lot of estrogen?

    • @user-vv6cb9vo7d
      @user-vv6cb9vo7d Před rokem

      @@swintegrative Wow! How did you know and high andogrens and DHEA-S according to the DUTCH Test. My serum blood for estrogen and progrsterone is normal.

    • @swintegrative
      @swintegrative  Před rokem

      @@user-vv6cb9vo7d Just bc your shgb is so high.

  • @macss6615
    @macss6615 Před 3 lety +1

    Great info ......doc my shbg is 64.1 noml/l total test 19.4 noml/l and free test is 0.266 noml/l ....my doc in uk says it’s normal but iv had low t symptoms for years and it’s affecting my quality of life ....in yr expert opinion from my results do u think I need trt or just something to lower my shbg....I’m 40 years old and would really appreciate yr knowledge...thank u

    • @swintegrative
      @swintegrative  Před 3 lety +1

      Hi mac ss, free T seems a bit low (I'm not use to these units) so raising your free testosterone may help.

    • @alialidjameleddine7285
      @alialidjameleddine7285 Před 3 lety

      @@swintegrative
      Hi doctor cld you tell us what are the medicaments or trt protocole which rise free testesteron,thnks

    • @swintegrative
      @swintegrative  Před 3 lety +2

      Hi Ali, yes I may do a separate video on this topic.

    • @ryanmiskin8925
      @ryanmiskin8925 Před měsícem

      did you end up getting on TRT? I'm 38 and my free and total T is almost half of what yours is.

    • @macss6615
      @macss6615 Před měsícem

      @@swintegrative never seen yr reply doc thank you 🤙🏻

  • @jerrycaddie838
    @jerrycaddie838 Před rokem

    I saw two endocrinologist. Im a male, My Estrogen is above 250 with two test. Both Endos say this is nothing to worry about. I do not do any HRT. I don't believe them and I'm worried. Any advise?

    • @swintegrative
      @swintegrative  Před rokem

      Estradiol is what is important and you want to check the Ultra sensitive estradiol too. There r genetic alterations in aromatase enzyme but idk without knowing your whole picture…

    • @jerrycaddie838
      @jerrycaddie838 Před rokem

      @@swintegrative will you see me? do you do telehealth?

    • @swintegrative
      @swintegrative  Před rokem

      @@jerrycaddie838 DrT@swintegrativemedicine.com

  • @amina-xe7wl
    @amina-xe7wl Před 10 měsíci +1

    Is it normal to have a high shgb if you have type 1 diabetes?

    • @swintegrative
      @swintegrative  Před 10 měsíci

      Not if you are taking insulin. Insulin usually lowers SHBG.

  • @johnnymedd3899
    @johnnymedd3899 Před 8 měsíci

    What about finasteride?

  • @scottsmith7348
    @scottsmith7348 Před rokem

    Hi. I'm a 64-year-old male that works out 3-4 times a week. I do HIIT and lift weights. I also do intermittent fasting 16/8. . My total T is 1086 (high). SHBG is 89.00 (high) Free Adrogen is 42 (normal) and Free Testosterone is 12.9 (normal). I was taking a "natural" testosterone booster which I stopped when I get these results. I did have prostate cancer 3 years ago and did 2 rounds of brachytherapy radiation I am cancer free now. It runs on both sides of my family. I knew I was going to get it, just didn't know when. I didn't know if that could have something to do with this?

  • @tomaszzieba315
    @tomaszzieba315 Před 3 lety

    Hi!. I'm 27 male without libido problems, with quite good body composition. There are my last lab results with ranges:
    Albumin 46.1 g/l (35 - 52)
    FSH 5.06 mlU/ml (1.50 - 12,40)
    LH 4,64 mlU/ml (1.70 - 8.60)
    Estradiol 18,10 pg/ml (11.30 - 43.20)
    Prolactine 11.70 ng/ml (4.04 - 15.20)
    Total Testosterone 864 ng/dl (249 - 836)
    SHBG 65.76 nmol/l (18.30 - 54.10)
    I've calculated free testosterone, it is 12.2 ng/dL. So basically my total testosterone and SHBG are above range, free testosterone is below. What can be the cause of this result?

  • @mattanderson9283
    @mattanderson9283 Před 3 lety

    I’m a 28 year old male. My total T is 741 ng/dl, free T is 18.09 ng/dl, and my SHBG is 54 nmol/L which all seem to be on the higher end of normal. I don’t understand why my SHBG is this high given the amount of free testosterone I have. My estradiol was measured at 34 pg/ml which is also on the high side of normal. Could that be the reason why my SHBG is on the higher end?

  • @lolje2095
    @lolje2095 Před 2 lety +2

    Hi, could the cause of low sedrive, bad erections and low sperm volume be the cause of high shbg? My total t was fine. Shbg not checkdd yet

    • @swintegrative
      @swintegrative  Před 2 lety +1

      Yes it can because if something is causing high SHBG there is less bioavailable testosterone (low free T). Low Free T can cause low libido and ED. The part that does not fit is the sperm count. To my knowledge SHBG does not relate to sperm count.

  • @bettysanpedro
    @bettysanpedro Před 3 lety +2

    21 y/0 male = no past medical history only surgeries = Tommy John and Labrum slap 3 repair. Results are below. Seeking clarification = has seen 3 endocrinologist and all have different responses
    Free T = 899
    SHGB = 63.4
    Albumin = 5.2n
    T4 = All within normal range
    BMP = All within normal range
    No sex drive, losing weight and body mass, no history of diabetes in the family, loss of appetite, depression. All onset of symptoms for the last 3 months and no reason for this complete overall health change.
    Please help, I don't know where else to ask for assistance

    • @swintegrative
      @swintegrative  Před 3 lety +1

      Hi Beatriz, get a comprehensive evaluation of digestive tract (through a naturopathic or functional medicine doctor). You may not have any overt digestive symptoms but it is a common source for chronic health issues of unknown etiology. Also is that total testosterone or free? what are the units?

    • @bettysanpedro
      @bettysanpedro Před 3 lety +1

      @@swintegrative it is actually for my son, not me. I gave both free and shbg above for him

  • @ArizonaMMJ
    @ArizonaMMJ Před 3 lety

    Use. The. Board. Behind. You.

    • @swintegrative
      @swintegrative  Před 2 lety

      Thanks for the suggestion. I am working on some changes.

  • @Harishankar-ec4bk
    @Harishankar-ec4bk Před 2 lety

    Sir help me my shbg 57 please help me i am from india i never take supplements

  • @ikaikadowsett4508
    @ikaikadowsett4508 Před 3 lety

    How do we contact you best directly?

    • @swintegrative
      @swintegrative  Před 3 lety

      You can email me at DrT@swintegrativemedicine.com

  • @desmomotodesmomoto2033

    Stress, bad diet, low animal protein, and animal saturated fat consumption, vegan diet....watching porn....etc

    • @swintegrative
      @swintegrative  Před 11 měsíci

      Haha

    • @rik9833
      @rik9833 Před 6 měsíci +1

      You are underestimating this issue for high shbg low free test one and normal test one. Fix all of these and nothing changes it's like a curse. All of ot these guys with the symptos of mentioned in the beginning are aslo physically active. So its not like their a guy that jacks off all day and eat what ever they want.

  • @TyShep06
    @TyShep06 Před 11 měsíci

    Too scattered

  • @larrymalavear3099
    @larrymalavear3099 Před 4 měsíci +1

    I'm sure your are a good doctor but you talk too fast and you are assume we know what you are talking about. Please speak plain English.

  • @Karel8X
    @Karel8X Před 11 měsíci

    First half is a useless intro, second half lists a few irrelevant reasons like infections, but not one useful or relevant piece of info. Waste of time.