Antiviral Pharmacology

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  • čas přidán 9. 07. 2024
  • ​​SUPPORT/JOIN THE CHANNEL: / @dirtymedicine
    My goal is to reduce educational disparities by making education FREE.
    These videos help you score extra points on medical school exams (USMLE, COMLEX, etc.)
    For educational purposes only; NOT medical or other advice.
    Some videos contain mild profanity and hyperbole solely used to assist with memorization. Viewer discretion advised.
    Opinions are entirely my own.

Komentáře • 98

  • @Lucky-ff9pd
    @Lucky-ff9pd Před 4 lety +251

    The voices of med school I've become very attached to: Dr. Sattar, Dr. Ryan, Sketchy Micro guy, and Dirty USMLE

  • @alitantawy2222
    @alitantawy2222 Před 2 lety +11

    one way to remember the hep c drugs :
    -If it ends with "previr" like "previous" so think NS3/4A , also starts with p as in protease .
    -" ASVIR " like after and starts with an A so think "NS5A"
    -"BUVIR" starts with b so think "NS5B"

  • @professorkhan5315
    @professorkhan5315 Před 4 lety +48

    Really great video!! I wanna add that a major differentiating factor between Foscarnet and Cidofovir is that Foscarnet has a seizure risk (I just think of S for seizure)

  • @redache467
    @redache467 Před 4 lety +50

    -previr = protease
    -buvir = 5B RNA bolymerase
    -asvir = 5A

  • @user-ul2sd8yc3g
    @user-ul2sd8yc3g Před 3 lety +34

    As usual, Great video
    One note , i think that viral thymidine kinase adds only one phosphate to some of the anti-herpetic drugs ( acyclovir , valacyclovir and famciclovir as I remember) and the other 2 phosphate groups are added by cellular kinases, not the viral one

  • @obadadaher4851
    @obadadaher4851 Před 2 lety +15

    give CIDofovir with probeneCID

  • @akinolarukayat6475
    @akinolarukayat6475 Před 2 lety +2

    Have had trouble remembering and understanding these drugs. You made it easier to assimilate. Thank you

  • @brookeanderson2631
    @brookeanderson2631 Před rokem

    Love the way you come up with tips and tricks to remember names and mechanism of action. Thanks!

  • @IG-qv6sh
    @IG-qv6sh Před 3 lety +6

    I'm waiting for part 2 of it. This was the most helpful thing in my learning antivirals

  • @Umir445566
    @Umir445566 Před 4 lety +31

    Thank you so much dude You are a legend. Any chance we can get a signaling mechanisms videos for hormones?

  • @SG-gw5xo
    @SG-gw5xo Před 2 lety

    Thank you so much for the video, you deserve 1 million subscribers!!!

  • @latifullah8574
    @latifullah8574 Před 3 lety +5

    You made it so easy and I am waiting eagerly for HIV anti vitals. Thanks for helping us

  • @serellamadole
    @serellamadole Před 2 lety

    Great video! You made the material so easy to digest.

  • @pallavighatnekar1653
    @pallavighatnekar1653 Před 3 lety +2

    For cidofavir you can remember given IV saline as I V is in the name cidofa VI r. Thanks so much for your information Dirty Medicine.

  • @wacomundo9599
    @wacomundo9599 Před rokem

    Dude, thanks so much! I’ve had to give avyclovir a handful of times in the ED and i never new the actual mechanism behind it.

  • @saintsam7397
    @saintsam7397 Před 2 lety +1

    THANKYOU FOR NEVER ADDING MUSIC TO YOUR GOLDEN VIDEOS.

  • @Muuip
    @Muuip Před 4 lety

    Great summary!
    Very helpful! 👍

  • @xaaboopinkly
    @xaaboopinkly Před 4 lety +3

    I really don’t know how to thank you!!!!!!

  • @stephenharris-dr
    @stephenharris-dr Před 8 měsíci

    8:23 - I think it is because of the purine ring structures in the drugs (Acyclovir, Valcyclovir and Famcyclovir). Anyway, your channel help me a lot during my preparation for MRCP part 1 and part 2 written exams. I really appreciate it. Thank you.

  • @ddfelder2
    @ddfelder2 Před 4 lety

    Thank you!

  • @xxamulyaxx
    @xxamulyaxx Před 4 lety +1

    thanks mate...
    simple slides...
    love from INDIA.

  • @raulblancoazcuy8308
    @raulblancoazcuy8308 Před 3 lety

    I loved your video. Thanks

  • @4agus
    @4agus Před rokem

    Great video, so useful! you made it really easy. Thanks Dirty

  • @AnilKumar-lo5rn
    @AnilKumar-lo5rn Před 3 lety

    i watchd ur videos ovarion tumours very excellent sir....nice pneumonice.....its very help a lot for me

  • @PowderChaser
    @PowderChaser Před 3 lety

    Another beautiful video!

  • @marianacostaR
    @marianacostaR Před 3 lety

    Very good!! As usual

  • @drswetaruparel
    @drswetaruparel Před 4 lety

    Very helpful !!! Thanks 👍

  • @marine3144
    @marine3144 Před 4 lety +2

    You just taught me better than my prof

  • @junaidmushtaq9421
    @junaidmushtaq9421 Před 3 lety

    Thank you so much.. This is high yield for board examinations and u made is easy for us.😍

  • @raghadraghad7976
    @raghadraghad7976 Před 2 lety

    so helpful ! thanks a lot

  • @luckymaisha
    @luckymaisha Před 4 lety +26

    Can you possibly do one on antibiotics/microbials? Love your videos by the way!!! Thanks so much for making them

  • @ambersani6889
    @ambersani6889 Před 3 lety

    Thank you, Sir... plz upload part 2 as well

  • @mahnoor7726
    @mahnoor7726 Před rokem

    Love all of your videos 👌👌👌👌

  • @tijinmathew6478
    @tijinmathew6478 Před 3 lety

    In hepatis C NS5B inhibitor which is a RNA -DEPENDENT RNA polymerase is supposed to block step n0 .3 right?

  • @drhoneybee973
    @drhoneybee973 Před 2 lety

    Dirty med you are great👍👍..thank you for making things easy-peesy..by any chance we could get a vid on anti-microbials!!!

  • @abdulmohsenalmutairi7102

    Thx 🙏

  • @awesomepabla7061
    @awesomepabla7061 Před 3 lety

    God bless you

  • @MedManiac1
    @MedManiac1 Před 3 lety

    legend!🔥🔥

  • @bhatwasim2831
    @bhatwasim2831 Před 3 lety +1

    Love from Kashmir

  • @cayladoo_1
    @cayladoo_1 Před rokem

    u r amazing

  • @Lucky-ff9pd
    @Lucky-ff9pd Před 4 lety +1

    Cellular enzymes add the 2nd and 3rd phosphate

  • @yashpawate1306
    @yashpawate1306 Před 4 lety +3

    This is just in time for my Microbiology shelf exam. Thank you so much! Please upload the HIV drugs too before saturday!

  • @Lopakaracing
    @Lopakaracing Před rokem

    I can't find the JOIN button anywhere.

  • @enginoengin1174
    @enginoengin1174 Před 4 lety +3

    Part 2 pretty please 🤓🤓

  • @christopherpatrick6949
    @christopherpatrick6949 Před 4 lety +9

    Dirty, the absolute worst topic to learn is pediatric developmental milestones. If you could make a video for that I would be eternally grateful.

  • @ramzarukia120
    @ramzarukia120 Před 4 lety

    love it

  • @Greanestbean
    @Greanestbean Před 6 měsíci

    Awesome

  • @mohamedmetwalli3064
    @mohamedmetwalli3064 Před 2 lety

    awesome

  • @vinodalbuquerque2488
    @vinodalbuquerque2488 Před 2 lety

    Sir plz explain on Lamuvidine HBV antivirals inhibitors.

  • @pramodthapa2517
    @pramodthapa2517 Před 4 lety +1

    desperately waiting Viral Hepatitis doc

  • @nurulaliahrizal
    @nurulaliahrizal Před 4 lety +1

    You're an incredible teacher! Btw please do anti-HIV video.

  • @tinashealthbeautyworld8396

    Can you also please do Molecular cell videos too? Thank you 🙏 so much in advance

  • @emerecene
    @emerecene Před 10 měsíci

    Can you do one about NSAIIs and Antibiotics? And I wonder why you didn't mention other Hepatitis types?

  • @crimzonart1269
    @crimzonart1269 Před 3 lety +1

    Please upload video on floppy infant
    Regards
    Dr. Gawher

  • @kenmiguel2986
    @kenmiguel2986 Před 3 lety

    Please do an HiV antiviral video

  • @alih6953
    @alih6953 Před 3 lety +1

    Great video mate amazing job! I think there is mis-spelling. It is Simeprevir

  • @elsatkkful
    @elsatkkful Před 4 lety +7

    Hey Dirty! Thank you for your videos, I know you're working hard to bring us these videos. Could you please make a video on the high yield microbiology. Thank you

    • @DirtyMedicine
      @DirtyMedicine  Před 4 lety +11

      It’s a huge topic of that I would need to break into several smaller videos

    • @aj7147
      @aj7147 Před 4 lety +1

      @@DirtyMedicine pls make more and more pharma and immuno videos pleaseeee !you the besttt....pls open a blog too like medicoawesome

    • @christopherpatrick6949
      @christopherpatrick6949 Před 4 lety +2

      This is what sketchy is for

  • @monirafarah4391
    @monirafarah4391 Před 3 měsíci

    Is this for step 2 only? I heard him say step 2 and I’m studying for step 1?

    • @kenibe3507
      @kenibe3507 Před 2 měsíci

      You need to know this for step 1.

  • @yasinozkul6590
    @yasinozkul6590 Před 3 lety +1

    l-e-d-i-p-A-svir (5A)
    s-o-f-o-s-B-uvir (5B)

  • @missionvision99
    @missionvision99 Před 9 měsíci

    3:39 6:14 8:11 10:15 11:12 12:29 17:27 18:40 fo SSS carnet

  • @lichh64
    @lichh64 Před 3 měsíci

    I love u.

  • @mohammadadnan6374
    @mohammadadnan6374 Před 3 lety

    U need to make your own course like pathoma or b@b

  • @usmleislife3396
    @usmleislife3396 Před 4 lety +2

    Hey can u make video on biostat hypothesis alpha and beta errors confidence interval... it will be very helpful

    • @otto9875
      @otto9875 Před 4 lety

      Search on here USMLE biostatistics. There’s a guy i think his names Dr. randy something who Dirty endorsed for his bio stats review. It’s good

  • @PtolemyXVII
    @PtolemyXVII Před 4 lety

    Very interesting! However 1) the antivirals in the AMI group would also block exosomes- due to exosomes uptake of sialic acid, and therefore also affect exosomes' action on T-cells by inhibiting them. Wouldn't this be hugely problematic and compromise the immune system? 2) the antivirals in the cyclone group, wouldn't it also inhibit RNA polymerase in cardiac cells as well as other normal cells due to its inhibition of thyamine kinase? This would mean that normal cells wouldn't be able to replicate. Thoughts?

    • @Ifeany1
      @Ifeany1 Před 3 lety

      the drugs are activate by the virus....the first phosphylation step, making it more specific to cells infected by the virus.

  • @Ruqaya_pearl
    @Ruqaya_pearl Před 4 lety +4

    I dont know why im here, i have a surgery exam!

  • @alhasanmd7305
    @alhasanmd7305 Před 4 lety

    Pharmacology profs disliked this video

  • @lgchinadragon
    @lgchinadragon Před 3 měsíci

    thymidine kinase, not thymididine kinase, which you keep on saying. I get this too with phenylalanine lol

  • @majidbashir7102
    @majidbashir7102 Před 4 lety +1

    Hi sir.
    Isn't part 2 yet available,???
    Part 2 of this video Non HIV drugs ??

  • @coverton
    @coverton Před 2 lety

    Sofo5Buvir

  • @maryalex9316
    @maryalex9316 Před 3 lety

    I just wanna express my gratitude to Dr.Ono on CZcams for curing my HSV 1&2. God will bless you Dr Ono

  • @bobbyboygaming2157
    @bobbyboygaming2157 Před 3 lety

    your video would be half as long and easier to watch if you didnt wast so much time saying "this is like so high yield" like every 5 seconds

  • @younaskhan7343
    @younaskhan7343 Před rokem

    For best pharmacology classes follow Dr Malik Nouman official