Finasteride || How it acts? || Mechanism, side effects & uses

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  • čas přidán 5. 07. 2020
  • Finasteride (Proscar) inhibits metabolism of testosterone but still antagonizes its actions. How its possible? Its all due to its active metabolite dihydrotestosterone (DHT) which leads all the actions of testosterone as it shows more affinity on androgen receptors.
    So elevated levels of DHT leads to few of the pathological conditions like Benign Prostatic Hyperplasia (BPH), acne, alopecia and even hirsutism. In this context, Finasteride inhibits type II 5-alpha reductase enzyme therefore it reduces DHT levels in serum.
    #finasteride
    #topicalfinasteride
    #finasteride5mg

Komentáře • 197

  • @jaquelinemanuel5716
    @jaquelinemanuel5716 Před 3 lety +6

    Thank you so much for your videos. They are easy to understand and I am learning a lot.

  • @dasfunkateer7573
    @dasfunkateer7573 Před 3 lety +5

    Thanks for the pertinent info... 👍

    • @egpat
      @egpat  Před 3 lety

      Welcome, thanks for watching.

  • @kgopu24
    @kgopu24 Před 3 lety +1

    Very nice explanation, How long Finasteride is taken for grade 3 prostate enlargement. Should it be taken throught life like anti diabetic or hypertension drugs. looking forward to your valuable reply

  • @princeberry626
    @princeberry626 Před 3 lety +6

    Very good info, makes me know what is taking place in my body👍

    • @Krishnaaa2244
      @Krishnaaa2244 Před rokem

      Still taking it?? Do u face any side effects?? Hope u will reply:()

    • @TheUwaisPatel
      @TheUwaisPatel Před 6 měsíci

      ​@@Krishnaaa2244been taking for 7 months, no side effects

  • @jhiludevnath3420
    @jhiludevnath3420 Před rokem

    Thanks a lot for the information.

  • @sudiptakumardas6159
    @sudiptakumardas6159 Před rokem +1

    What is it exactly that finasteride does when we say that it "inhibits 5-Alpha reductase"? Does finasteride cause your body to reduce the production of 5-aR?

  • @josepe2448
    @josepe2448 Před 3 lety

    Is there a way to contact you to ask a question?

  • @mikeanthony8699
    @mikeanthony8699 Před 2 lety +8

    What is it exactly that finasteride does when we say that it "inhibits 5-Alpha reductase"? Does finasteride cause your body to reduce the production of 5-aR? Or does it specific prevent 5-aR from working on testosterone? If it is the former, than there may be unintended consequences because 5-aR is also needed to reduce progesterone to dihydroprogesterone as just one example. In other words, 5-aR is responsible for the reduction of many hormones to their dihydro-version. If we reduce the body's production of 5-aR, then it would seem that we are aslo reducing the conversion of many hormones to the dihyro-version

    • @roya89
      @roya89 Před 2 lety

      Anyone know the answer to this?

    • @mrofnocnon
      @mrofnocnon Před rokem

      @@roya89 It reduces DHT and shrinks the prostate.

  • @videowithsongsandmotivatio4073

    How many month take it results??

  • @mumtazahmed8099
    @mumtazahmed8099 Před rokem +1

    Excellent video. Very helpful to understand the treatments. I am 80+ and taking both Proscar and Tamsulin daily. Please advise how long these be continued? Thank you.

  • @acquiesce100
    @acquiesce100 Před 2 lety +1

    Why does it cause ejaculation problems and loss of libido?

  • @ravikumarmeshram6226
    @ravikumarmeshram6226 Před 3 lety

    Nice explanation sir. Thank you

    • @egpat
      @egpat  Před 3 lety

      You're welcome, thanks for watching.

  • @MisterPete3
    @MisterPete3 Před 2 lety +1

    Nice video very clear

  • @-Hooman-
    @-Hooman- Před 3 lety +31

    In 6 months of taking it 1mg a day it did reversed my hairs to when I was 18 years old

    • @illimattic
      @illimattic Před 3 lety

      What age did you start losing your hair?

    • @-Hooman-
      @-Hooman- Před 3 lety +4

      @@illimattic I first noticed when I was 29 than after 32it just went crazy

    • @illimattic
      @illimattic Před 3 lety +4

      @@-Hooman- finasteride must be a miracle drug for you then if you got your 18 year old hairline back. I'm only 2 months in with fin and min and getting good results so far.

    • @-Hooman-
      @-Hooman- Před 3 lety +3

      @@illimattic Yup after literally month 4 I did noticed dramatic result I'm in month 7 now but I am really pleased with the result if I wasn't starting with finasteride trust me couple years down the line I was completely bold

    • @illimattic
      @illimattic Před 3 lety

      @@-Hooman- Are you still seeing even better results at month 7?

  • @ahmadal-khaldi2663
    @ahmadal-khaldi2663 Před 3 lety

    Thank you

  • @Govind80567
    @Govind80567 Před rokem

    Sir can u explain.. How does Topical finasteride work. .. Does it have same side effects as Oral..)??

  • @logoutjason4689
    @logoutjason4689 Před 4 lety +7

    well done, very succinct and clear

    • @balmightys
      @balmightys Před 4 lety +2

      Cmon man you don't gotta lie

    • @leofrasier6716
      @leofrasier6716 Před 3 lety

      @@balmightys lol I'm done lol

    • @leofrasier6716
      @leofrasier6716 Před 3 lety

      U dried it lol

    • @logoutjason4689
      @logoutjason4689 Před 3 lety +2

      @@balmightys for a guy that doesn't speak English well, he gave a pretty straightforward and concise presentation about a fairly complicated biological process. let's see you do that in his language

    • @TwinMillMC
      @TwinMillMC Před 3 lety

      Really? His accent is so heavy I could hardly understand him.

  • @Priteshlodh
    @Priteshlodh Před rokem

    Sir, what is the role of type 3, 5 alpha Reductase enzyme?

    • @Vectorman2X
      @Vectorman2X Před rokem

      keep your self away from this, you will regret it those enzymes have many actions on human body and hormones plus neurosteroids that act as modulators of human behavior dont take the risk

  • @SureshCSCNetcafe
    @SureshCSCNetcafe Před 3 lety +2

    If we use finasteride.
    It prevents testosterone convertion into DHT
    but finasteride doesn't prevent testosterone convertion into Estrogen.
    So please tell me the best Estrogen blocker.

    • @workingclassilliuminaty
      @workingclassilliuminaty Před 3 lety +7

      brocolly

    • @rrnmd
      @rrnmd Před 3 lety +2

      Excellent question Suresh. Anastrozole is the most common ingredient we use in our molecular medicine rebalancing clinic. The 'precise' dose of each molecule is dependent upon one's natural genetic enzyme rate of activity, discovered in your BRC lab analysis. We commonly use between 0.05mg QD to higher doses every 5 days, depending upon follow up monitoring of the biomarkers inside the person's body. I'll share a secret, due to the short half, Finasteride will not be effective long-term for prevention of hair loss. And remember that the prevention of further hair loss does not equal 'regrowth' of miniaturized follicles. That requires another molecule, latanoprost, for example, a specific prostaglandin agonist, used topically. I hope this helps. -dR nettles, StopandRegrow Hair Inc. , Chief Scientist

  • @andy_collins91
    @andy_collins91 Před 3 lety +5

    Derek has entered the chat...

  • @theartist9505
    @theartist9505 Před 3 lety +1

    👍👍👍

  • @itshamdounbitch
    @itshamdounbitch Před 2 lety +2

    Is taking 5mg of finasteride every 2 weeks effective will minimizing side effects? (Similar to the 1mg x3 per week?)
    Cant seem to find the 1 mg tablets where I’m from, can only get my hands on 5mg gel capsules (cant be split into smaller doses).

  • @abhishekbhardwaj583
    @abhishekbhardwaj583 Před rokem +1

    I am using finastride from 2 weeks and my haifall increased is it normal ?

  • @friendofbeaver6636
    @friendofbeaver6636 Před 2 lety +4

    I've been taking finasteride for over 6 years to treat BPH. My facial hair is substantially thicker than before.

    • @musiccanfirst5697
      @musiccanfirst5697 Před rokem

      What is your dosage ?

    • @friendofbeaver6636
      @friendofbeaver6636 Před rokem

      @@musiccanfirst5697 5 mg/daily.

    • @jspbipro
      @jspbipro Před rokem +1

      Have you experienced any negative side effects? Thanks.

    • @friendofbeaver6636
      @friendofbeaver6636 Před rokem

      @@jspbipro I've gotten used to the occasional balance issues. The retrograde ejaculation isn't much of a negative. My breasts have enlarged, slightly. ED symptoms and decreased libido are inevitable with BPH.

    • @mrofnocnon
      @mrofnocnon Před rokem +1

      @@friendofbeaver6636 yikes!

  • @hardiksatani6688
    @hardiksatani6688 Před 3 lety +1

    my hair become be thinning on my crown area. And I have no hair fall, can I take finastreride ...

    • @S4h4r4s
      @S4h4r4s Před 2 lety

      How old are you?
      Also, I recommend having your blood tested and speak with a doctor to see if your body can take it or not, and what dose size mg/day.

    • @hardiksatani6688
      @hardiksatani6688 Před 2 lety

      @@S4h4r4s I'm 21 year old।।। I taking 3 mg per week

    • @tomshaji
      @tomshaji Před 2 lety

      Should consultr a doctor first

    • @eop3otrima231
      @eop3otrima231 Před 2 lety

      @@hardiksatani6688 any results? side effects?

  • @videowithsongsandmotivatio4073

    How many month take this result??

  • @markoshea8993
    @markoshea8993 Před rokem

    Nice video

  • @badalbhadke7060
    @badalbhadke7060 Před rokem

    I m using this from 2 year 1 mg daily but I feel that my sexual desire decrease so I stop using this. Now what side happen on me it will be normal as before or hair fall increase fastly...?
    My sexual desire increase or not..if yes then how much time it take...?

    • @DilshadAlam-gr4qt
      @DilshadAlam-gr4qt Před 3 měsíci

      Bro did u get recovery from sexual side effects of finasteride?

  • @doctorarvindram
    @doctorarvindram Před 3 lety +1

    I got a notification

  • @dannypope1860
    @dannypope1860 Před 3 lety +72

    That’s some thick accent homie

    • @shans2408
      @shans2408 Před 2 lety +20

      and some knowledge which you are welcome to find elsewhere if you don't like the accent

    • @johnblah1040
      @johnblah1040 Před 2 lety +4

      @@shans2408 lmao

  • @reignrelic
    @reignrelic Před 3 lety +8

    I’m scared as fuck to take this drug 😫

  • @ramakrishnaraop3968
    @ramakrishnaraop3968 Před 2 lety

    I am using 5mg Finasteride for the last six years for prostrate control. The drug seem to be working well.There are no side effects except gradual loss of sexual desire. Want to know whether it is safe to continue the drug perpetually?

  • @silentkiller4722
    @silentkiller4722 Před 3 lety +12

    I am taking finastride 4 months for hairloss.side effects premature ejaculation,watery semen,ED,chronic fatgue.This problems are only in first month.

    • @perkabi9678
      @perkabi9678 Před 3 lety

      did you relized hair regrowth or thicking?

    • @silentkiller4722
      @silentkiller4722 Před 3 lety +7

      @@perkabi9678 Yes.It increase hair density and thickness.

    • @SuperRickyjenkins
      @SuperRickyjenkins Před 3 lety +2

      @@silentkiller4722 Do not come of it yet what ever you do matey. Go get blood work done now before you come of it. cortisol testosterone everything.If you haven't had blood work done before there is no maker to work back too.But at least if you have it done now when you stop taking it you will have a benchmark to work too before your apocalypse.Stay safe bruv.

    • @Law116
      @Law116 Před 3 lety

      How do you use it? 1mg every other day?

    • @silentkiller4722
      @silentkiller4722 Před 3 lety

      @@Law116 Every day 1 mg .

  • @videowithsongsandmotivatio4073

    Does smoking causes increase dht level??

  • @doctorarvindram
    @doctorarvindram Před 3 lety +2

    Where is the Chinese dude who commented on it

  • @الغاز_اسلامية

    How long does it take for Finasteride side effects to appear?

    • @RandomGuy-hv7tb
      @RandomGuy-hv7tb Před 3 lety +3

      It taked 3 months for me i am using it From 10 months and i am feeling it's side effects, i have to much low sexual desire now, i am thinking to discontinue

    • @RandomGuy-hv7tb
      @RandomGuy-hv7tb Před 3 lety +10

      Update: i have reduced my dose from 1mg to 0.25mg per day, now i am not feeling any side effects and finastride is working fine too...

    • @الغاز_اسلامية
      @الغاز_اسلامية Před 3 lety +3

      Great update man !!! , hope your results get better and better

    • @RandomGuy-hv7tb
      @RandomGuy-hv7tb Před 3 lety +2

      @@الغاز_اسلامية yeah my hairfall is stable now and i have a bit more quality hairs than before

    • @hannesbolman4710
      @hannesbolman4710 Před 2 lety +2

      @@RandomGuy-hv7tb How are you now my friend?

  • @MisterNarrador
    @MisterNarrador Před rokem +1

    I can't never understand Indu English, so confusing

  • @magnificencetv7424
    @magnificencetv7424 Před 3 lety +1

    i'm worried about fertility issues

  • @1stmoviefan
    @1stmoviefan Před rokem +2

    The ugly truth about all medicines for enlarged prostate is that they can't stop the prostate from getting larger as u age. I urge anyone suffering to have prostate surgery.
    I had it done it wasn't painful . I just regret not doing it sooner.

    • @mrofnocnon
      @mrofnocnon Před rokem +1

      What kind of prostate surgery did you have?

    • @fatfrreddy1414
      @fatfrreddy1414 Před rokem +1

      any surgery comes with risks...

  • @gbwhitewarrior
    @gbwhitewarrior Před 2 lety

    Here is a helpful hint for you you need to slow down your speech because your dialect is almost totally understandable to us English people either slow down or get someone else to do the presentation

  • @cray9925
    @cray9925 Před 2 lety +2

    Extremely and I mean extremely strong accent. Cool content thought but man that accent. Wow!

  • @zj3117
    @zj3117 Před 4 lety +11

    That accent is too tight but good info tho lol

  • @aliasgharmaleki7563
    @aliasgharmaleki7563 Před 2 lety

    Thanks. I'm eat 2mg 😂

  • @was544
    @was544 Před 3 lety +1

    Fe Nasty Ride

  • @anuragkhaund8363
    @anuragkhaund8363 Před 2 lety +2

    Be very careful about taking Finasteride guys, it causes hypertension.

    • @dukemd69
      @dukemd69 Před rokem +2

      Wrong! It can contribute to HYPO-TENSIN........lowering of BP.

    • @anuragkhaund8363
      @anuragkhaund8363 Před rokem

      @@dukemd69 It made my BP shoot up in just two months.

    • @fatfrreddy1414
      @fatfrreddy1414 Před rokem

      @@anuragkhaund8363 interesting ...my blood pressure is up so much I'm on medication to bring it down! not sure if it's the finasteride, or all the cakes I eat!

  • @michaeldomansky8497
    @michaeldomansky8497 Před rokem

    It is a poison!

  • @kinston201
    @kinston201 Před rokem

    Horrible drug. Post finasteride syndrome is real

  • @balmightys
    @balmightys Před 4 lety +22

    Could we get a dude that speaks english for christ sake

    • @doctorarvindram
      @doctorarvindram Před 4 lety +23

      I bet you can’t produce this knowledge if asked to reproduce in front of your senior. Shame on you , having a name of almighty and mocking someone for a mere language, which isn’t even an original language .

    • @dayumboydayum8461
      @dayumboydayum8461 Před 4 lety +41

      He is speaking English. He’s took the time to learn a secondary language for the benefit of people like YOU and myself. A little bit of respect goes a long way. Have a nice day

    • @doctorarvindram
      @doctorarvindram Před 4 lety +8

      Dayum boy Dayum well said my man 😊🙏🏻

    • @seductivegoat2403
      @seductivegoat2403 Před 4 lety +3

      Have a bit of respect mate, thank you come again

    • @subie1019
      @subie1019 Před 3 lety +8

      Sorry bro, but the world ain’t americans/ British, you gotta respect someone from another country who tries to learn your language even if their first language isn’t English

  • @donlessnau3983
    @donlessnau3983 Před 2 lety +1

    Good info but why not have someone who can speak clear English. I can't understand half of what this guy is saying. Very poor.

  • @rene2582
    @rene2582 Před 3 lety +4

    when you speak english, i will see your videos