Sympathomimetics or Adrenergic Receptor Agonists pharmacology MADE EASY!
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- čas přidán 25. 07. 2024
- Sympathomimetics/ Adrenergic agonists are substances that mimic or modify the actions of endogenous catecholamines of the sympathetic nervous system. Direct agonists directly activate adrenergic receptors while indirect agonists enhance the actions of endogenous catecholamines.
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Norepinephrine acts ona1a2andb1 so it never increase blood pressure you said why????u
Instead of increase, use word decrease and your query will be solved.
Because she said, it will never decrease B.P.
Beta 1 receptors r in the heart, so by stimulating beta 1, B.P will not be decreased.
Can I get these notes.
You can find them on the website. Link is in the channel description
@@MedMadeSiriuslyeasy ok thnku
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I don’t understand a point ! Alpha 2 is minimizing sympathetic so how it’s classified as a sympathomimitic drug
Same question
Sympathomimetics are those agents which act on all the receptors of the sympathetic nervouc system that includes alpha one, alpha two, beta one, beta two and dopamine receptors.
If you say that it will activate alpha two receptors and thus negative feedback will inhibit further norepinephrine release, then you can say the same about normal norepinephrine release during a normal sympathetic response. By that, I mean that let’s forget about the alpha two agonist and just say that we simply have a normal physiological sympathetic response, even then, there will be functional alpha two receptors on the presynaptic neurons.
That means that you shouldn’t focus on it like that. You should only think that sympathomimetic drugs are those which act on the sympathetic NS receptors regardless of where they are present because these receptors have different functions even in normal physiological response.
Don’t just think about it in terms of fight or flight response because different receptors have different functions
It'll be better if you call them Adrenergic Receptor Agonists
and then you can figure out their uses by thinking what receptors have what function normally
I hope that explains your concern
Thankyou so much for making it clear!♥
@@MedMadeSiriuslyeasy thank u sir 💗yesterday we learnt our first lecture in pharmacology,im 2nd year med student,and today i asked about this to my doctor she had the same answe of urs 💗
You’re welcome. ⭐️