Schizophrenia Adjunctive Treatment - Minocycline
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- čas přidán 3. 06. 2023
- Hello, Everyone! I'm Stephen. Today, we're exploring the antibiotic minocycline as a potential adjunctive treatment for schizophrenia.
Schizophrenia is a complex and debilitating psychiatric disorder. Antipsychotic medication has been the mainstay of treatment. But, a quest for enhanced treatment efficacy and better management of residual symptoms has driven exploration into adjunctive therapies. Among these therapies, the antibiotic minocycline has surfaced as a promising candidate, owing to its intriguing neuroprotective properties. In this post, we'll delve into the exciting intersection of schizophrenia and minocycline, discussing a recent groundbreaking study and sharing personal experiences of minocycline as a treatment adjunct.
Background on Minocycline
Minocycline, a semi-synthetic, second-generation tetracycline antibiotic, is primarily used to treat bacterial infections. However, its potential extends far beyond combating microbes. Its anti-inflammatory, antioxidant, and neuroprotective effects make it an intriguing candidate for treating various neurological conditions, including schizophrenia.
Minocycline and Schizophrenia: Unveiling the Connection
The root cause of schizophrenia remains a mystery, though mounting evidence points towards inflammation and oxidative stress playing critical roles in the disorder's development and progression. For example, cytokines, proteins that regulate inflammatory responses, have been found elevated in the blood and cerebrospinal fluid of individuals with schizophrenia. Such observations have led researchers to consider anti-inflammatory agents like minocycline as potential adjunctive treatments.
Preclinical studies suggest that minocycline can attenuate microglial activation (a neuroinflammation marker) and mitigate oxidative stress in the brain. In addition, it has also demonstrated neuroprotective effects in models of neurodegenerative diseases. Considering these findings, testing minocycline in clinical trials for schizophrenia was a logical progression.
Clinical Evidence: The Exciting Breakthrough
A compelling meta-analysis published on March 8, 2023, in the International Journal of Molecular Sciences titled "Minocycline as Treatment for Psychiatric and Neurological Conditions: A Systematic Review and Meta-Analysis" was instrumental in revitalizing interest in minocycline as an adjunctive treatment for schizophrenia. Panizzutti, et al. doi.org/10.3390/ijms24065250.
The study concludes that minocycline, particularly in schizophrenia treatment, shows a significant overall benefit. It acts through anti-inflammatory and neurotransmitter pathways to exert its effects and appears safe and tolerable for neurological and psychiatric conditions.
A Series of Promising Studies
Several studies echo this promising potential of minocycline as an adjunctive treatment for schizophrenia. For example, a study in the Journal of Clinical Psychiatry (2013) revealed significant symptom improvements in early-phase schizophrenia patients treated with minocycline compared to those receiving a placebo.
A 2015 meta-analysis of 12 randomized controlled trials found that minocycline significantly improved negative symptoms and cognitive function in schizophrenia patients, while a double-blind, randomized controlled trial in 2017 further confirmed these findings.
A comprehensive meta-analysis in 2020, incorporating 14 randomized controlled trials, reinforced minocycline's potential as an effective adjunctive treatment for schizophrenia.
Stephen's Personal Journey: Minocycline as an Adjunctive Treatment
Diagnosed with schizophrenia, Stephen embarked on a 12-month course of minocycline (200 mg/day) during the acute phase of his condition.
Stephen's treatment journey was filled with the typical uncertainties and apprehensions of trying an unconventional approach. However, the improvement in his condition was noticeable. The negative symptoms that often marked his day-to-day life-apathy and social withdrawal-showed significant improvement. The hallucinations, delusions, and so-called positive symptoms were also better managed.
Conclusion
The link between minocycline and schizophrenia is an exciting development in psychiatric treatment research. While clinical studies and personal accounts like Stephen's give us hope, we must proceed cautiously. More research is needed to determine the safety and efficacy of minocycline as a long-term treatment for schizophrenia and establish the optimal dosage and treatment duration. One thing remains clear: the journey to understanding and treating schizophrenia continues, and every discovery, every personal account, and every bit of progress counts. So here's to hoping that with continued research, we may unlock the full potential of minocycline in managing schizophrenia and, in doing so, improve the lives of countless individuals affected by this complex disorder.
#schizophrenia #anxiety #mentalhealth #depression
Thank you Stephen for decreasing the stigma. You are a valuable man. We need more people like you.
Thank you Laurie! That means so much to me!
I'm only seconds in, and I'm VERY VERY interested!! My brother had so many episodes of strep throat as a kid, which can result in the inflammatory conditon called PANDAS that oftentimes literally just seems like the person/kid is a jerk/rebellious/angry/etc. And then later, he developed psoriasis on his scalp, which is an autoimmune illness and hugely exacerbated by inflammation, and later had major infections in his nose.
I won't burden you with the details, but he disappeared a couple years ago after what I, looking back at the clues, believe was either a manic episode with psychosis or the development of schizophrenia. I hope he's somewhere out there getting help. My parent and I were talking just the other day about how maybe his strep infections and/or psoriasis played a part in distorting his perception of us. A lot of his paranoia right before cutting us off centered on my parents; but he's so intelligent and articulate that I think none of us realized something psychiatric was probably happening until it was too late to prevent him from officially leaving our lives and threatening legal action should we ever try to contact him again.
I hope he's ok, wherever he is. I think about him often, especially when new treatment options arise. I research this sort of thing a lot, after I myself began dealing with my own psychiatric issues a couple of years ago.
Thank you for all you do! You're so well-spoken, bright, kind, and brave. I'm so so glad you and your family realized what was happening early enough to get you early intervention, which seems crucially important. You are doing VERY IMPORTANT work, paving the way for other families to spot the signs, gain insight, and change the trajectory of loved ones who experience psychotic disorders
Thank you for sharing Danny. I am very sorry about your brother. I am hopeful for his future. I appreciate your incredible comment. It means a lot to me and helps me keep going.
Prayers for your family ❤
Very interesting! My son has recently developed symptoms of psychosis. He is autistic. Years ago when he was 18-21 he went to a wonderful Pediatric Neuropsychiatrist Dr Carl Hansen in Minnesota. He found in his tests that strep A I think it was ( one of the streps) causes many symptoms from Tourette’s, to OCD and many others. He put him on an antibiotic ( not sure what as this was over 25 years ago) but it really seemed to help him.
I’m very curious as how this will work! ( later when he was no longer on Medicaid he/we couldn’t afford the $500 a month for the med so he dropped it.
You are so relatable Stephen. I was diagnosed 19, I’m 46 now. It hurts to know you went through things I did. I never wanted anyone to have my experience but you did. We are very unique and I’m so glad your family are supportive and engaged. They clearly love you it’s good to see you got that. I’m a new subscriber, can’t really binge watch your stuff though I’d like to but the subject matter reflects memories of my experience which are difficult to process.
It's a tough and rough journey hope you are keeping well
you are strong simon, a warrior. you got this. much love.
Did you hear about the recent case of April Burrell? 20 years fully catatonic, but recovered via immunosuppressants. Schizophrenia is almost certainly multiple diseases and syndromes, which are grouped as one due our ignorance.
No. I don't think so.
No I hadn’t, however my Dad had read about it this past week in the Washington Post. That sounds fascinating though and I will look it up! Thank you for sharing!
I'm convinced it's something a garbage term due to the fact that is likely many different diseases that may well have different treatments (in the future).
Wonderful your absolute’team approach’ and vulnerability in sharing which few people …..
Are you as a person known to be a perfectionist? If in any way, things ‘not going to plan’ can be hugely disappointing and debilitating …..
When sharing how this went, I again thought that this is SUCH VALUABLE. Learning experience for you about real life - this is a very real example of the disappointment people have to deal with every day - putting a huge effort into something that crashes…..
You are doing all the right things in getting you back up again - SO GRATEFUL!
Please add this experience to your collection of ‘negative experiences’ - VASTLY important and needed to cope more independently with life, as as your resilience and understanding for why this upsets you, and that it is not the end of the world, despite the efforts you made, grows - you will deal with this better
As your dad said - you have a near flawless youtube track record and you’re wanting to expand - treading on new ideas - it will fail, like with the most successful people in life - leave some room for failure and work out from your mistakes, e.g. may just trying a 5 min clip with new technology would have been a smarter idea - this is what people dom and if they realise that they had a flop - they see it for that and simplify steps and try again….
A lovely example from here in Australia - not sure if you follow tennis which I love…l Ash Barty was the woman’s Nr 1 for some time….. and she quite at the top to pursue her family life - soooooo smart and wise.
In her earlier days her coach’s recommendation for her was: Ash needed to learn ‘how to loose’…. He specifically put her on a trajectory to facilitate a journey where she could loose and learn to deal with it; he viewed it as soooo important as he knew, if she goes too far, and become too successful, at a high level on the tour if she looses, it will throw her and she may loose track completely…..
You see this in real life every day - people who win and win and never learn to deal with disappointment and ‘how to deal with that’….
I am so pleased you have had this ‘safe experience’ - and I pray as all the other things, this will continue to build your capacity and skills
Disappointment and sadness is not wrong - we all face it - but does it put us under or can we identify ‘flaws’ in what we attempted, laugh a bit about it, try again maybe in smaller chunks - and always leave (not toooo much) but a tiny space for failure/things going wrong….
Have a blessed day🕊️
amasing! which are the immunosuppressants or where I can read more?
My sister has schizoaffective d/o and im a Registered Nurse. Im thrilled to find your channel. Education can help change so much. Thank you both.
This really intrigues me. Because way back in 1999 an Army Dr prescribed me tetracycline for a terrible staph infection/acne. I had to continually take the medication for about 4 months to clear up the infection and I found myself in a very peaceful state of mind even while on deployment. I never tied it to the medication because it was an antibiotic. Thank you for this young man!!! I will be speaking to my Doctor very soon.
Even though the antibiotic treatment was published March this year I've heard of that antibiotic treatment for schizophrenia/psychosis before. I believe they are using it in Australia a few years back the article in the journal was fascinating and seemed promising.
I enjoyed this uplifting positive video. Thank you Steven and Steve
Thank you Pauline! I’m so glad you enjoyed the video. Have a happy and healthy rest of your day!
I knew someone who was on tetracycline, I believe, for schizophrenia, and this was decades ago. I don't think it helped.
I may ask my daughter's nurse practitioner if she would consider this as a neuroprotective treatment for my daughter. She had a first episode of psychosis in December and pulled out of it quickly, but still is cognitively not where she was prior. She isn't fully back to her former levels of functioning. I also worry about her having another psychotic episode, so anything to keep her protected is so valuable. Thanks for sharing, as always.
Thank you Helen. I wish you and your daughter the very best
Thanks for the video Stephen glad your feeling better and some good advice. Sounds like the effort you put into that video made you exhausted then ill. It’s good to monitor your energy levels and know when to stop and rest very important in managing schizophrenia. Nice to see your dad supporting you again. Have a great week 👍
Thank you very much Graham! You have a great week too!
A very interesting video, Stephen. Minocycline can cause increased intracranial pressure and very bad headaches. That's why I asked previously if you were being treated for acne or some other condition requiring a tetracycline before the onset of your schizophrenia.
Also, antibiotics can have a profound effect on gut bacteria. Taking prolonged antibiotics without a plan afterwards to re-establish a good gut flora can cause problems. I'm not sure, however, if what constitutes a good gut flora has been fully agreed or whether it differs according to conditions, it's still being examined, I think.
Gut flora and vitamin / mineral irregularities should, however, always be considered when treating any condition. It is important also to maintain a good diet that fosters good gut bacteria when treating any condition.
It is important, too, to take into account any additives ( the edible and topical types), work school, or home exposure to chemicals, pesticides, or hormone disruptors that may have been exasperating things. Even too much sunlight exposure on the eyes can trigger problems. This sounds like a lot to deal with Stephen, but if you start by addressing one thing at a time, it's not so bad. The doctors can look at the vitamins, minerals, gut bacteria, CRP levels, etc. for you ( if necessary).
The gut is now considered a second brain. Getting the bacterial balance right is very important because bad bacteria can produce or induce the production of bad chemical messengers that can affect the brain adversely.
On a separate note, I suppose it's good that you experienced difficulties with your video. Firstly because it allows you to have another lovely lunch. Also, it teaches that as long as nobody is dying, not to worry about things. Take a rest when things go wrong and give it a go again tomorrow or another day. What's the rush...
About medication... if things change with gut, lifestyle, stress, and sleep, medication must also be looked at in tandem. The side effects of medicines demand this.
Thank you Noreen for providing this excellent information! I was not being treated for acne or any condition before the onset of my psychosis and schizophrenia. I had not been taking any medication before then. My headaches started shortly before the onset of my psychosis in January 2012 and resolved by the end of May 2012, long before I started Minocycline. I didn’t experience any adverse effects from the Minocycline treatment as far as I can remember.
I had a terrible migraine caused by minocycline, I forget exactly why I was prescribed it, but I will never forget the headache it caused. So yes just be aware if you try it and start to feel off
I noticed that when things 'go wrong', it can really upset me. This can be anything from not getting an umbrella to go up, computer problems, car issues, etc. I always make sure to keep everything in good maintenance and also (almost) always get a warranty, so that if something goes wrong it can be fixed. Just sharing in case this is helpful... also, I think it would be funny to show us snippets of the unused videos or for outtakes! Maybe the part with Stephen eating his parfait...! :)
Thank you Carolyn for sharing! It was helpful. I may show portions of that in my next video. Thank you for your suggestion!
This is such a wonderful video, really helpful for people wanting a better understanding of managing schizophrenia.
Another fascinating and informative video. Sharing your lived experience is so valuable. And your dad’s perspective is so interesting as well. Just amazing how natural you guys are and generous of you to invite us into your living room. Thank you.
Thank you from both me and my Dad Paul! I am very happy you enjoyed the video!
Very valuable information. My son has been recently diagnosed so I thank you both for educating me on the subject. Amazing to witness the father's love; he deeply immersed himself into neuropsychiatric research. 🙏❤️
Thank you for openly sharing your story. Most people don't feel comfortable with explaining their experiences. I've had severe depression, anxiety, panic attacks that I've delt with since age 19. I then had my first temporal lobe seizure with distorted feelings of reality. It was misdiagnosed for 20 years. I now have effective treatment.
Thank you for sharing and joining my journey Jenny
I'm in my 70s. It took 25 years for it to be diagnosed correctly. It's a little difficult condition as there can be hallucinations and sensory oddnesses, also depression. I am seizure free (other stuff going on though). Temporal lobe seizures don't go away with maturity unlike other seizures so be very cautious re stopping. I had severe breakthru seizures after 40 years on Tegretol. Fortunately it's well tolerated--have taken for quite a long time now.
So thankful you came out of the psychotic state. You are A brave Young Man!❤
So glad that things are turning around again. You are so brave posting these videos.Every time I get a negative response to one of my comments, it throws me off. I can't imagine the courage that it takes to put yourself out here and being vulnerable. You are so awesome, shining a beam of hope to all of us who are impacted by mental health issues.
Such wisdom! Way to bounce back (showing your reslience!) Thank you for sharing on this cutting edge research...I will share with my group!
Thanks Lisa! I really appreciate it. Have a happy and healthy rest of your day!
in my personal experience the depressive episodes coupled with anxiety really are tied with delusional thoughts and very negative thoughts but it kind of spikes and then gradually goes away. the times when it is happening there doesn't seem to be anything that stops it from happening now I don't about the medications you're talking about personally but yeah for me what has helped is gradually realizing I have this trait or tendency to ignore the positive effects I'm having on the world and in my life because really then any kind of failure can seem like a big set back the positive of that tendency is that it makes you better at solving problems because being aware more problems makes it easier to solve them but it can also be relentless.
Wow! I just finished watching this video! Amazing! Excellent information and presentation!
I am sorry about the loss of your Terranea video, Stephen. I understand the importance of sharing those moments of stepping out on your own for yourself and with your audience. However, I truly believe you can reframe your disappointment.
The fact that you physically accomplished and experienced a trip to Terranea and enjoyed yourself is monumental! Like your trip to Texas….you did that on your own! You are building an resourceful internal strength of personal confidence you did not have a short while ago! The great thing about Terranea it’s only 5 minutes away! Perhaps you can plan to go there any day even on a whim! You know you can do it! It’s in your cellular memory now as a resource! So proud of you!😊
Thank you very much Gayla!
Great information! love following your journey. So glad you got through the rough week! 😊
Stephen, it's truly okay when things go wrong. Life is full of ups and downs. Being disappointed is a normal feature of life. Its part of the human condition.
Letting go of the unrealistic pressure and expectations we put on ourselves and figuring out how to stop ruminating when situations don't work out.. are things that we all learn as we evolve and grow older, regardless of whether we have psychological issues or not.
Acceptance of a difficulty and diverting your attention to something more positive or more achievable is very sensible.
Your difficult situation actually turned out to be a valuable learning lesson in videography which you can now benefit from, when you next choose to do some film making.
There really is no such thing as perfection anyway. All we can ask of ourselves is to do the best we can.
Both of you lovely people ....fill your lives with doing things that make you happy.... both together and apart. There's so much out there to explore that's amazing and extraordinary and funny.
Be kind to yourselves.
Sending lots of healing love to the both of you. 💛🙏
Every time seeing your post brightens up my day give there is hope for recovering and living with a smile
Thank you Kalai! That makes me very happy!
Great video guys! Thanks for sharing this research and your story with us!!
Thank you so much putting these videos out. The lived experience is so challenging. I really appreciate you drawing the connection between anxiety and increased psychosis. We have just been through the most horrific and distressing fiveish days where my nineteen-year-old son believed strongly and was taking action slight self harm Because he believes he is possessed by demons. We had been trying Zyprexa. Also interesting to hear your thoughts about how antipsychotics can sometimes cause psychosis. We believe that the Zyprexa increased our son's anxiety about thoughts that he kind of always has in the background but Amplified them. As soon as we stopped after a 3 week trial, he was always talking 600mg seroquel too, then the "possession" seemed to calm down. We also added clonozopem as anti anxiety. So he still has baseline delusions but less depression and anxiety currently
This was great guys,im carer for someone ,but i myself now have a physical disorder,its so hard when you try and it doesnt work,im not techy,but arty,its important to hear your stories
Thank you!
Hi guys, I’ve watched several videos now and appreciate you sharing with us. Sorry to hear you lost all that cool video footage Steven. It’s always frustrating when you’re trying something new and it doesn’t work out the way you had intended it to. You’re other videos are all great so I’m sure you’ll get it on the next take or the one after that-the most important thing is that you tried and keep on keeping on and that’s what’s important and awesome about it. Much love guys. Thanks Steven 😊
You guys are terrific. Thanks for sharing so much needed information. Great teamwork.
Such an amazing channel! Bless you for your strength! Continued success ❤️
You are so impressive Stephen. Amazingly open and informed about your illness. And a talented videographer. Keep on keeping on. You are so impressive.
Steven, I've just found your channel and, as someone who has very severe psychotic depression, I'm finding it so helpful. Thank you.
Thank you Stephen and Steve for sharing. You give me hope!
I truly appreciate and I am thankful for you having the courage and strength to share your experience and informing the public and helping remove the stigma. I also am wondering if you, Stephen or your dad could share in more detail of signs and symptoms of the onset of schizophrenia, I have a Lil one I adopted and he is autistic, has ADHD and ODD sensory processing disorder, and his bio dad has schizophrenia and ASPD and other mental disorders, his mom has bipolar.
You guys are setting trends Thank you!
As far as the video think like the studios, Take 2!!!
I’m glad you did it am came trough it 😊
Blessings!!!
Thank you very much Bob!
🎉so proud of you both for giving us inside information about this delicate topic. Be well both you and your family 💞🙏🍀.
Very informative. Thanks for your honest and candid remarks. I’m sure it’s not easy. But you come across very sincere. That’s the beauty of your blog.
Thank you Ronald! I appreciate it!
You guys really wonderful family you’re helping me to get idea for my son is treatment and I appreciate your videos
Thank you Nimo. I wish your son the very best.
Great video! Thanks for sharing! It was very interesting 😊
Glad you enjoyed it! Have a happy and healthy rest of your day
Stephen is so lucky to have found a good support system within his own family. Balanced support system is so important, neither sweeping issues under that rug, also neither helicoptering. I'm happy for Stephen. This video is also reminding me to get some more turmeric supplement. There's a new form I just found out about.
I learnt so much, thank you both for your videos. They are so helpful and your both such lovely people. I was wondering if you suffered any negative issues from long term antibiotics, such as stomach or bowel problems, or thrush?
Thank you for a very interesting informative video. I learned a lot from this video about schizophrenia and treatment.
Interesting topic! Thank you for sharing this
Stephen,
My family has navigated many of these obstacles. Your presentation is so valuable. I appreciate how you are truthful and vulnerable and funny.
Parfait sounds delicious.
I salute Steve! You have made an intensive study in order to understand the illness of your precious son. You both should reach out to the scientists who published those studies. They surely would find your experiences helpful in further studies
An interesting video thank you Stephen. This antibiotic is also being studied in bipolar illness and these new novel approaches are extremely interesting in the way we think about these mental illnesses and for improving the future treatments available. Have you ever thought about doing a video on trialing a strict medical ketogenic diet for a few months? This is the type of diet first used to treat epilepsy and now being trialed in bipolar and dementia.
Thanks for bringing this video to us and for sharing all that you do. I do have a theory (and please bear in mind I'm not a health professional etc. as I share this theory), and that is in times of experiencing trauma there is a "body memory" formed, which is stored in the "sub"-conscious. I personally see the effects of trauma as a cocktail of emotions all happening at the same time. We experience trauma simply because for whatever reason we aren't able to cope/process all the complexities of what we are enduring in those moments. The more prolonged the traumatic experience quite possibly the more profound the effects are.
Putting myself into the shoes of a 12 year old experiencing debilitating and unexplained headaches, the on-set to psychosis and psychosis itself would in my opinion (I'm not a health professional) constitute a very profound and prolonged traumatic experience, and there will be a whole cocktail of emotions, panic, being overwhelmed etc. in that mix. It is my opinion as these aren't processed a "body memory" is instead formed, and perhaps this is also true for anxiety disorders, and one emotion experienced through now current situations (and it could even be something as subtle as a smell can send someone back to that body memory all done in the "sub"-conscious) which in turn triggers that "body memory" and all the other "raw emotions" that were present in that time. All stored in the sub-conscious so all one is experiencing is the body memory which the mind then tries to make sense of and perceives it as something else. Hope that makes sense. The answer if this theory is correct is possibly to go back and decipher all those raw unprocessed emotions by gaining full closure on those traumatic experiences so that the "conscious mind can distinguish the present and stop attaching it to the unprocessed from before. We experience trauma as we aren't equipped to process it. The easy way to gain closure is to re-visit those painful memories describing them from a spectator/witness perspective (detaching oneself from those raw emotions etc. by approaching the whole ordeal from a different point of focus) while a trained therapist does the emotional processing for them and closure gained from the backwards and forwards comparing of notes, all the while the therapist is acutely aware of pain thresholds and how to address them through consoling, reassuring and supporting. Again if that makes sense. Hope this has been of some help. 🙂
Thank you John! Your comment was very helpful and wise! I really appreciate your continued support of me and my channel! Thank you again. Have a happy and healthy rest of your day!
Much respect to you both. Question, during the initial 2 acute years, how was Stephen still able to understand the need for, and take, daily medications? How wonderful that you were able do so, Stephen.
Hi Stephen and Steve, I thoroughly enjoyed your video, as always :) I'm glad scientific community is looking for new and better ways to treat mental illnesses, I am not very well informed on the latest research but from what I heard and seen, making new psychiatric medications is incredibly long and difficult process (it can take decades from what I've seen), so pharmaceutical companies kind of gave up on it since it doesn't generate them much or any revenue. I really hope that changes since I think 3/4 patients choose to discontinue their psychiatric meds within a year of treatment because of significant side-effects (don't quote me on that, I can't recall the source, but I'm pretty sure it's correct information).
As far as your video goes, if you learned from it, it's not a failure. It's just something that happens in life occasionally, I imagine it didn't feel good but, again, it's life. In my opinion people should always wish for a smooth sail but know that there might be a storm as well, (I hope I made myself clear there, again, English is not my main :). Thank you, Stephen and Steve, you guys are awesome, and please stay awesome :)
Thank you very much Ingvar83! I really appreciate your continued support and all your comments!
Keep up the good work helping to educate people🙏
Thank you very much!
Thank you for your channel. Sharing your knowledge and first hand experience will help me to understand what my loved one needs and help me be more helpful in understanding her symptoms and what she needs to manage her illness. Right now she is doing very well. Thank you again! By the way I am a new subscriber. Stephen you are so blessed to have devoted parents. I am enjoying listening to you both. I am learning about schizophrenia and enjoying listening to you sharing your life with us!!
Thank you Pamela! I really appreciate it. And thank you for sharing. I am so happy your daughter is doing very well right now!
@@SurvivingSchizophreniaStephen its my sister. I'm sorry I tried to be discrete lol. Our journey with her has been so challenging for our whole lives. She has been in and out of treatment for years. I am her legal guardian now. We are in our sixties. It has only been in the last year, with lots of fighting the system and advocating for my sister, and her willingness to comply, that has been such a blessing. I want to keep learning all I can since I am technically her "voice" to advocate for her. Love your story and you sharing your life!
Thank you very much. No worries. If you want to please continue to share. Through sharing you help de-stigmatize schizophrenia too. It has been a very tough illness in our lives. But we are stronger together.
@@SurvivingSchizophrenia your willingness to share your story and tell the world about a most misunderstood and stigmatized illness is life changing for so many people, including me and my sister. We are blessed that she has a team of people who want to help her, but I can tell they don't really understand what her illness is. They treat the symptoms but they have her lumped in with people who have drug addiction problems. They think they can "cure" her by teaching her how to cope with drug addiction! They think she will "graduate" and "learn" to manage her life and live independently if she just stays off of bad drugs and follows their program of "recovery". We have to tell them over and over that she cannot ever live by herself. We tried that and it failed! She is plagued by hearing voices and being out of touch with reality. For that reason she can never live alone and make decisions on her own. She is very vulnerable and gets confused and has memory problems. Yes her medication has stabilized her but she will never be completely free of symptoms. She has learned to check in with me or her caretakers when she is confused about her reality. As her guardian, I have the final say in her treatment, but whatever I say is worthless if she decides she no longer needs treatment. I do have legal power to force her into hospitalization if she refuses but for now she is doing well and understands the need to comply. I maintain close contact with her, she is in a 24 hour group home, her medication is supervised daily. I attend meetings with her, and so far she is doing well. Stephen I am so glad you understand the importance of staying on your medication and continuing to advocate for yourself and that you have your parents to help you. I am learning a lot listening to you and your dad talk about your experience in living with schizophrenia. Thank you.
Great job guys.
amazing and interesting thanks for sharing
Thank you for your videos, Father and Son! From what you are describing, it sounds like Steven could now be diagnosed with more of a Schizoaffective disorder, rather than Schizophrenia, would you agree?.. - based on the fact that Steven has symptoms of Schizophrenia (such as psychosis) + a mood disorder (depression), for which he takes Lexapro. Anxiety is also a mood disorder, so in combination, they seem to make a Schizoaffective disorder (depressive type). I'm not sure there's any value for you in having the condition re-assessed, I merely pay attention to how the mood component adds to the picture. Once again, thank you.
Thank you very much! I have not been diagnosed with schizoaffective disorder, only schizophrenia and a separate anxiety disorder. You have have an excellent question and I plan on covering this in a future video!
I am not schizophrenic but have had major depression and I still have bad days from time to time.
I bought it on my own without prescription because I didn't thought doctors would prescripe it for my needs and I needed help.
Long story short: The time I took it, it helped me quite a bit to improve my very bad mood at that time. Better and faster than any antidepressant and that time.
Only stopped taking it because I thought it might not good for my gut.
Sometimes I still think there is something wrong with my immune system that's unknown. But who can tell?
Thank you two for sharing. My son has bipolar and would love to see other ways to deal with his condition. Thank you.
My daughter is on low dose Clozapine 50-100 mg for bipolar. Mania is gone, some anxiety still there but it also helps for bipolar.
blessings keep up the good work;) thanks for sharing
Thank you! You too!
Thank you for the beautiful video! I am a mother of children with autism. In October 2023, I heard Dr. William Shaw , founder of Great Plains Laboratory (now sold as Mosaic Diagnostics) gave a talk, saying that HPHPA and other metabolites of anaerobic Clostridia in the guts of autistic and schizophrenics (can be detected in urine) , showing antibiotic use and subsequent dysbiotic gut flora can give rise to metabolites causing symptoms of autism and schizophrenia. He treated them by pulsing with antibiotic and anti fungal drug (candidiasis is almost always a concurrent occurrence, also checked using urine labs). There is a case of a 23 year old Japanese man whose psychosis went into remission with antibiotic use for pneumonia. I am wondering (which you omit) if addressing intestinal bacterial overgrowth could resolve some of the root causes? My mother-in-law would get “sundowner” and increased in behavioral challenges when she eats sugars (candidiasis) my children with autism would have meltdowns when they eat foods not in their specialized diets. When I hear you say you ate a parfait - something that sounds so innocuous - that /sugars would cause candidiasis for my boys and for my mother-in-law, causing breakdowns. In my case, sugars will cause me to have itch, hyperactivity and severe depression the next morning. I am grateful for your beautiful video. I wish you could expound upon dysbiotic gut flora, bacterial and candida overgrowth, their metabolites such as HPHPA and effects on schizophrenia. I hope you can connect with Dr. William Shaw of Mosaic Diagnostics! Blessings to you!❤
Thank you for the information and encouragement!
This is very interesting/exciting re: the various so-called "mental illnesses". I'm wondering have you have heard that the ketogenic may help schizophrenia? The channel "Living Well with Schizophrenia" has a current interview. This is done in a controlled situation, because you need monitoring and assistance.This is a real thing with research. This is a very good video. Clear and concise.
The answer you are looking for is called PANDAS Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections, but can also be associated with other viral/biological infections. It is an infection that causes the immune system to attack the brain.
Nice to meet you I too suffer the illness.
When I had nerves severed, I was also put in minocycline. One thing it did was make me look like I had a permanent tan! The reason I came off of it 10 years later was because it caused too much Candida growth, which made me extremely unwell. Long story short, I'm not sure if it helped my neurological problems (MS-like symptoms). To date, I no longer have a large intestine, and several other lover abdominal parts are also gone.
Thank you for watching and sharing!
thank you, great presentation, i hope it works for people, keep up the good work___i am very interested in PANDAS from strep causing all kinds of problems
Bless your heart 🙏🏻🙏🏻
Interesting video guys, nice one. Sorry to hear about the video that went wrong, tough when it happens like that but it happens ay. Was wondering if you played minecraft by any chance Stephen? Hope you're doing good today
Thank you very much Dardan! I really appreciate your support. Yes I do play Minecraft!
@@SurvivingSchizophrenia You're most welcome man. Good stuff
We'd possibly enjoy your video. Artistically speaking, much interesting imagery comes from what some perceive as "failures". Bet you could cut and splice it to make a truly original work. You might love a digital media class!!
Does this med treat Toxoplasmosis?
Btw, I am so jealous of your having a good father!
What do you guys think about the new upcoming meds for sz next year such as Karxt and Ulotaront?
Great vid btw!
Thank you! We have heard about them and are still looking into them
Do you think they will ever be a cure for skitzophrenia?
Thanks!
Thank you so much Laurel! I appreciate it very much.
2nd comment, i really thing an infection started this off or vaccines, heavy metal exposure ??, for example, a teenage girl in canada had to get up to date on vaccines for high school, and she had i think 4 vaccines in 1 day, and they accidently gave her the wrong vaccine (menigitis ? ) for one of the shots and she has had seizures since.
You are awesome!❤
Sad that the Clozapine was withheld for so long. It’s known to be highly effective in the treatment of psychotic mental illness.
Check out studies on the effects of gluten and schizophrenia!
Interesting, antibiotics also improves chronic fatigue syndrom, cfs, which is also probably caused by inflammation in the brain..
Interesting. I think antibiotics can play a major role in... reducing serotonin and good gut bacteria in your intestines, which plays a part in gut brain barrier function. From what i've read, some antibiotics cause depression due to these reasons. Not sure about Minocycline just using my general knowledge and experience. Did you read up on Mirtazapine?
Thank you Vince! I did read up on Mirtazapine. I am currently taking Lexapro which also is an antidepressant
A friend of mines son is currently cutting out sugar and low carbs. He is improving
Thank you for sharing. I also am cutting out sugar
I had an auto immune disease at the same time I was psychotic.
I think schizophrenia is an umbrella term, with many causes.
Inflammation and glutamate need to be considered.
Is a diagnose of schizophrenia temporary for a period of life or for the whole life?
Because I know 5 people who are recovered and 3 do not take meds for decade now, 1 takes only 2 mg aripiprazol and one takes 50 mg closapin or depending of the day up to max100 mg clozapine and she is totaly fine the last 15 years.
Love you both.
Thank you so much!
Thanks afternoon school
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Specially
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Rated. .
Go
Adivan put me in the hospital with severe depression and they kept giving it to me. I went off from it and the depression went away within 2 days. I lived suicidal for 4 years after taking Ativan, which almost took my life. I would see if replacing Adivan with another drug is possible. I am telling you it was up and so down on that drug for me. Please read this.
Thank you for your videos. Our 15 year old is currently being tested for schizophrenia. I wish there was a way I could speak to your dad. Any way to message him?
Thank you Robert. Please leave any questions you have in the comments and my Dad and I will get back to you as soon as possible.
This sounds like a severe migraine disorder or at least what I’ve seen people experience. Is there a link?
I HAVE SOME INFO. , FROM SOME RESEARCH I HAVE DONE INTO THE AUTO IMUNE AND NERVOUS SYSTEM! I HAVE REALLY COOL DATA AND IDEAS! i WILL DIG OUT AND SHARE FOR YOU STEPHEN,NOT THAT I KNOW MORE ,BUT I KNOW WITH THIS STUFF, ANY RESEARCH /IDEAS ARE GREAT TO LOOK AT AND ANALYZE! GOD BLESS YOU!
Have you been tested for Lyme or bartonella?
Yes I have been tested for both. Thank you for sharing this valuable information
@@SurvivingSchizophrenia thank you for responding ♥️ have you been tested for bartonella by a lab other than labcorp or Sonora? For example vibrant or igenex labs?
@@kzl7711do these other labs have more thorough testing?
Sheesh! I took Minocin for acne as a teenager.
This would be almost too good to be true. Is schizophrenia maybe caused by gut bacteria and they just didn't know it?
There is hope and a cure 🙏🏻🙏🏻
Everyone's experience of psychosis is possibly different I would guess (I'm not a health professional etc. just someone who has experienced psychosis), but my understanding of psychosis is it's often driven through someone's imagination/belief system and fear can feature heavily in that mix too. Hallucinations could be a major trigger to the imagination kicking in and stress can be a contributing factor to having hallucinations. One offset to fear is time. Even though someone could be heavily over-whelmed with their immediate consciousness/focus is on their beliefs, the sub-conscious in my opinion will be aware that as time is elapsing nothing untoward is happening. This time element will start to kick in and as time progresses I think it's only natural for someone to start questioning their beliefs etc. as their worse fears aren't coming to pass (if that makes sense). The point I am trying to make here is time in itself can be a healing property...
I'm thinking they are mostly similar. I think you are right about time though. I think that's why everyone ends back up in the hospital no matter if they take meds or not. It seems to come in waves for months at a time. I don't agree with chemical lobotomy pills. They are killing people's empathy with them as well. It's my life I can fight against it how I want. Even with all my fellow sktizos talk down on me and act like I gotta be unhinged. Well I'm not and I believe I will be the one well in the end because I'm fighting it. I'm not lobotomizing myself
Very true John! I do believe that time can be a healing property. That has been true for me. Thank you very much! Have a happy and healthy rest of your day!
They didn't prove anything, hot air. Very common to keep announcing potential breakthroughs in chronic diseases, but nothing changes for the people with the condition.
Can use minocycline for MDD ??? Please reply to me 🙏🏻🙏🏻🙏🏻
There were some trials where it was shown that mino was antidepressive.
It also kills proteobacteria which are depression- and inflammation-promoting, at larger doses since proteus harbors quite AB resistant strains.
Since it is no joke, that's got to be regulated with a doctor.
@@fragileomniscience7647 thank you
Brilliant information thanks and bless you both. We call those particular antibiotics, the atom bomb over here😂 Myself & 2 of our adult kids have movement disorder (TS) and sensitive to some medications, the antibiotics give me candida Overgrowth in my oesophagus😂🤔
I have to eat stealthy prebiotic salads and probiotic yoghurt, sauerkraut and fermented honey garlic, or I have a sensory overload..
I wondered if this happens to anybody else
my son has schizophrenia . . every other day 911 comes my home. he does not eat no take medication and some time aggressive. just coffee and Marijuna and 5% food. need help to save my son health
I am very sorry to hear this. Thank you for sharing
What state are you in? You can get guardianship, you can petition for a psych evaluation. Just get him on Clozapine as fast as you can! Do what you have to do!
Sorry the channel is called metabolic mind, it's on utube
Thank you Karen
I would recommend reading brain energy by Chris palmer he has some interesting insights on the relationship between metabolism and mental illness.
Thank you for all of your work and sharing. It seems like a genetic illness triggered by environment from others experience. It's obviously a physical disease. My heart goes out to you❤
L.S.D type drugs come from fungi so do antibiotics.
Antibiotics definitely can have an effect on the brain.
I had epilepsy bad on phenobarbital the only cure I had was from the lord it’s spiritual it’s a deaf and dumb spirit 🙏🏻🙏🏻
I WILL BE BACK...LOL! YOU ARE SO TOTALLY AWSOME YOUNG MAN....TOTALLY!!! WARNING,I DO NOT SPELL VERY GREAT ,SO BARE WITH ME, LOL!
Wow
Do you have cats?
Toxoplasmosis carried by cats changes the mind of mice. A European doctor said that like 75% of schizophrenia people test positive for toxoplasmosis
please investigate 'targeted individuals"
This sprit is horrible
No. Only you can beat schizophrenia
Thank you Robert!