Cubane Ep 9 - *Actually* forming the MonoKetal
Vložit
- čas přidán 3. 06. 2021
- Some NMR results, planning out the UV cyclisation step and finishing off deprotecting the ketal. Are we actually achieving our goals?? Wild. Subreddit: / explosionsandfire
Join the Discord!! / discord
Twitter: / explosions_fire
Patreon: / explosionsandfire
Music is from the Aphex Twin soundcloud dump, track names are:
- m11stN lon
- 1 chunk 101
References: 1997 Lab scale paper: www.researchgate.net/publicat...
2013 Pilot Scale: pubs.acs.org/doi/abs/10.1021/...
"Cubane Derivatives for Propellant Applications" 1989
apps.dtic.mil/sti/pdfs/ADA210... - Věda a technologie
The tar is now tricking Tom into thinking that it's the product, it's getting smarter.
The tar will take over Tom's mind.
oh my fucking god lmao
@@californium-2526 it hasn’t already?
Organic chemistry is the art and science of creating large amounts of unidentifiable tar and a small amount of the intended product.
Me, trying to do a simple synthesis in a state-of-the-art lab, doing my best to be as careful as possible: gets absolute shit yield and shit purity.
This absolute madlad, doing a complicated as all hell synthesis in his fucking shed without a care in the world and super sketch methods: gets perfect purity and massive yields.
Fuck me mate, the fact that you got any product at all amazes me. Those ENEMA spectra are god-like tho. Fuckin get this man a Nobel prize already, jeez.
And the Nobel for absolutely massive nuts goes to; the scruffy lad on the back!
I absolutely feel you
Chemistry actually looks fun when explosion&ire is doing it. When I want to light a fire I need to follow a damm 12 step plan handed out to me by school. I understand we can't do dangerous things, but come on school your sucking everything that is fun out of practical chemistry with stupid step plans to follow.
He's come a long way from raging at s4n4
@@jeoshy1873 as stupid as it sounds, that type of step by step chemistry is what you have to do if you want to do the stuff he does. In my undergrad of college I thought I could do all this chemistry and that "easy" labs which taught me the basics were a waste of time. Looking back, it allowed me to learn all the skills I need with a safety net of not dying. Chemistry, especially inorganic can be extremely dangerous and the techniques like TLC can be expensive and dangerous to mess up. Not to mention even extractions&ire is following "steps" but is able to put his own twist on it because he understands the background chemistry. Trust me, if you stick with it you'll be able to do the cool stuff.
Mate. I'll be honest. I thought you would abandon us like everyone else, lmao
He left for cigarettes and actually came back
Just went to pick up some long neck VBs
LMAO - awesome
@@MySuperhappyfuntime ew, needs to smash a Milton Mango to get the gross taste of VB out of your mouth ;)
And cans of Somersby apple cider.
@@Alex-co7cq not to forget the trusty Strongbow
“Nothing but f***ing net.” Tom becoming the Ramsay of chemistry.
Finally, some good f***ing yields.
im an idiot sandwich
@@ExtractionsAndIre *tar sandwich
Ramsey is an aggressive unskilled cook that looks like a ballsack....
@@TheLinkoln18 and you are jamie oliver?
It's good to have you and your hate of yellow back in our lives. We have missed you.
I've missed uploading videos!
@@ExtractionsAndIre The new camera is lit too. It looks really well. I look foward to the next vid.
#StopYellowHate
@@IdiotWithEducation No
@@commanderarto3841 Issa joke man
I love seeing him excited about his purity
A rare moment, I'm so used to being disappointed
@@ExtractionsAndIre I'm a struggling chemist, I know the feeling. That's why I related with you. It's the best when your shit is the tits.
@@ExtractionsAndIre Man, the Dikethal NMR is beautiful, the tribromine, as you said is f*cking net
"HD extractions&ire doesn't exist, it can't hurt you"
HD extractions&ire:
It's ok. We don't know how reptiles work either. They are a little four legged mystery.
Mysteries science will never answer
I actually got inspired to look up why they need UVB and the answer was interesting:
• UVA light helps regulate behaviors such as feeding, diurnal movement, mating and similar activities.
• UVB light allows the synthesis of vitamin D3, which helps to absorb calcium.
• UVC light is not required for reptiles, but it can help kill bacteria. It’s important to note that at high levels of exposure this light can be harmful to most animals.
Source: www.zillarules.com/articles/understanding-uva-uvb-uvc-reptile-lighting (though google has many links for this)
....the more you know :)
@@LFTRnow thanks m8 you ruined the mysteries of reptiles for us.
(I am not actually this a joke)
was scrolling through my recommended and nearly shat myself when i realized this was a new cubane video
That's the enemahr effect.
@@carreg-hollt underrated comment
"Nothing but fucking net." That legit killed me
ahh, the TLC shenanigans and stuck stoppers really hit that synthesis lab course PTSD spot.
TLC = time lived crying.
When you become an organic chemist, your entire life becomes an endless synthesis lab course and you find many new ways to fail over the years.
@@AA-gl1dr it's like Biologists with PCR tests,
Pipette, Cry, Repeat
@@1224chrisng this is literally my life
@ Always exciting when you find a fun new unique way to fail a synthesis!
This isn't a series of videos, this is a saga.
It's a QUEST!
It's an Epic!
the quality really improved, looks like a movie
Worlds apart! Good to see the Cubane synthesis hasn’t died a death!
Cubane Crisis - in cinemas near you
He just bought a new camera that's 4k
I still don't know what Cubane is or does but this is just too entertaining.
Cubane is eight carbons, all bonded together in such a way that the molecule becomes literally a cube with carbons at the corners! It's a *really* tricky molecule to make, because carbon *really does not want* to be a cube, and so it's quite explosive :)
@@Nerdule quite quite explosive
@@Nerdule so, a substance for explosions&fire?
@@necrobynerton7384 im fairly certain that this part of his youtubes where he does all the cool chemistry has just become the factory for making more explosions&fire content. He has created his own infinite content loop!
@@Nerdule No cubane is not explosive, it is in fact very stable. It is instead a highly strained molecule with a lot of energy stored in its structure.
If you tacked on some more reactive and oxidizing functional groups like some nitro groups then you would have something energetic.
The further I get through my chemistry undergrad, the more I enjoy these videos!
Same tho
'congratulations, i'm sorry'
The emission spectrum of your reptile light might change as it warms up, so u could try taking another spectrum after a few minutes. Who knows, you might have more UV than you think!
You re probably right! Would explain why my spectrum and the spectrum on the box don't like up super well
@@ExtractionsAndIre Yeah always let gas discharge tubes warm up. It makes a huge difference.
I'm glad someone said this already
As a Canadian, I say "Enemar". Ain't nobody got time to enunciate 3 whole letters.
This was born the lawl
An enemahr a week keeps digestion in check!
HE'S BACK! It's good to see that you're still alive!
As usual i hardly understand any of it but i love watching ALL of it
I am binging your channels. I am 40 years old, have no knowledge of chemistry at all, and really haven’t a clue what you are making but I am totally mesmerised. The way you explain everything makes it easy to understand and exciting. I am amazed that you started most of this with chemicals I can buy at Bunnings. You are a legend mate and I hope you don’t stop these videos.
Thanks a lot mate, glad you like the videos!
Nice to have you back! There's nothing better than an Australian doing cladestine CZcams chemistry in his shed.
"I don't really know how reptiles work"
Better to keep your edge, don't let the Lab Lizard hear you say that. Through his reconnaissance he *probably* knows more about you than you do of him.
You had mentioned that you changed the audio and I was afraid that I would not get to see that microphone again.
But it is still here, and I can rest easy.
The last time though I think, so soak it in!
nooooooooooooooooooooooooooooooooooooooooooooooo!
See, the clamped mic is ICONIC for E&F/E&I. As much as PUSA.
What a legend the person who ran your samples. For free in the end?
For free like an absolute legend. Was happy to pay but nope
@@ExtractionsAndIre pay them in beers or spirit of their choice!
That analysis at a commercial lab would have been a pretty penny. Fucking analytical chem the bane of many a PhD students research!
@@ExtractionsAndIre Like an absolute legend that he is.
I did my chemistry masters on UV induced meta-photocycloadditons and I can confirm that cheap reptile bulbs are the best option for this situation. You touched on limiting the reaction time for clean products which is spot on. The way we did that was by pumping the solution through a thin transparent tube which we wrapped around the bulb (at a distance to prevent overheating). This way we got high intensity UV exposure over a short period which is designed to give high yield without too many side products forming from the product. I can recommend looking up flow setups for this. Also degassing your solution with nitrogen may help with your yield as dissolved dioxygen can get excited at those wavelengths and potentially run amuck with your reagents. Good luck and I look forward to your upcoming work :)
Replying so this comment gets bumped up, even tho it's been 8 months lmao
"I sometimes call it enemahr, I've had lots of people commenting they hate it, so I'm going to continue doing it" 🤣🤣🤣
Please never change
Hey there! I used to be a scientific glassblower for a university, and had to un-seize ground glass joints all the time. Take a gentle sooty orange flame like a candle (bunsen burner is ideal) and put it right on that joint. Keep rotating it to evenly distribute heat. With a little convincing, it will eventually come loose.... if its being stubborn tap it with something rigid but not metal. Use oven mitts ^-^
Wouldn't be one of those UV water sterilizer or germicidal lamps be perfect? They usually spit out a crapton around 310nm.
Ah yes, the crapton, my favorite subatomic particle
Are those craptons metric or imperial?
@@JazzyFizzleDrummers Craptonite is what causes his shitty yields.
I'll look into it!
@@mmmhorsesteaks Yes.
Uhhhm DCM and UV are not usually very good friends, I'd stay away from DCM and use methanol personally.
As to the UV step, I think your idea is great. You might want to consider actually running 2 or even 3 lamps (if they don't get too blisteringly hot) since you'll have much more secured coverage of the flask all around + consider doing this one inside due to the sunlight, might cause an issue (unsure on that one). If sunlight is mentioned in the paper as only being problematic if you *only* use sunlight for the cyclisation then it's probably fine to do this outside.
Good luck, and very glad to have you back!!!
Yeah maybe methanol is a better choice? The boiling point being higher is an advantage too
My man still refusing to buy a lav and hand-fumbling that shotgun mic.
Keeping it Shed.
imagine not keeping it shed just because you got an internship
No it's because of the audio quality, he MUST use the shotgun mic in his hand
Had a Cubane question on an organic chemistry exam this morning. Only knew what it was from your videos, cheers!
The ENEMAH machine is a real pain in the arse
This series began last August, when I was just starting my series of organic chemistry. Last week I finished the two semesters and I feel so different! I actually understand functional groups, NMR, TLC, and lots more
Ochem rly does make you understand chemistry as a whole.
*ENEMAH
Finally, Tom is back in making the cube!
Here's a reaction I never figured out that came about by chance decades ago, that anyone growing tomato plants could try, unrelated to things that go boom. At the end of the growing season when the vines are still green, tear up a handful or two of tomato vines in a kitchen blender with water added. Filter the mixture and save the filtrate. Add a small amount, maybe a few tablespoons or less of DMSO to the filtrate and you should get a green precipitate you can filter on a paper towel and let air dry for a couple of days. What might the product be and whether it would have any uses, I don't know.
"Sorry, I'm getting excited" - Mate, it's okay, you did this in your shed and had it confirmed by an enemar machine
XD
you need to get a UV lamp for a water purifier.
They'll also give your eyeballs a serious sunburn in a matter of seconds so if you do get one... be careful with it. seriously.
Mmm crispy eyes.
Yup, and be aware any real UV lamp will be crystal not glass (glass filters UV!), so take care in handling.
"2 out of 3 Australians will get skin cancer before 70"
"that's bloody *c o o k e d* "
saw this uploaded alt+f4 game its time to watch this
or as the first semester Students refer to it in organic chemistry: The Ænima machine.
Well, it is a Tool
"Die Eier von Satan", also on the Ænima album
"Dr.Satan", person posting about a Tool album
The name checks out.
HE'S BACK BOI
WITH SOME CUBE SCIENCE STUFF
the new cam is Lit !
Welcome back :)
I've got a tip for your KMnO4 TLCs. Either make it a bit more concentrated or don't blast it with your heatgun quite as much. In your compilation shot, on the bottom right is what you get when you get it right. With the complete palte staying purple and only the spots brighten up.
Since they already look like that when you take them out of the solution I'd say increase the concentration a bit.
I'm an engineering guy, not a chemistry guy, so tons of this content sails right over my head, but man do I find you entertaining to listen to!
Same, I'm so lost but enjoying it none the less
I love how unreasonably excited I get for a chemistry video not being involved at all. Always neat shit tho 🤙
Every now and then I have to stop and think how absolutely amazing this channel is.
I would think that in Australia you have enough UV radiation from the sun to push the reaction. Maybe go to the outback and perform it there, will make for a great chemistry+travel video.
(j/k)
True! Shame it's winter at the moment, but there's still probably enough sun
Travelling to the middle of the desert to do chemistry sounds kinda familiar...
@@ExtractionsAndIre right, you live in the bizarro world
@@pelegsap South hemisphere is the "bizarro world" lmao love it
our non-yellow overlord returns with another cubane video
that's some great enemahr results you got yourself there mate.
It's like every chemist has tourette's syndrome, they can't help but shake the flask.
They also can't keep from sniffing their reaction products, even if it's str8 up ether
@@Beardwhip could be worse, there's a guy on the e&f subreddit who likes to taste stuff, including carbon tet
I understand maybe 5% of what's going on, 10% at most but that doesn't stop me from enjoying the absolute chaos energy from this channel. I watch this a lot while I'm crocheting or knitting which is kinda funny to me.
There are also UV Tubes for water treatment in filtering systems for garden ponds.
You can buy them separately.
Just googled them. Seems to be UV C :/
But maybe there are others
Only a small part. There are practically no pure UVC sources out there.
HD minecraft chem is just the content i need for the summer.
I'm using that exact UVB reptile lamp with one of my students for a photochem project. It worked really well for us
Magic trick for removing glass stoppers stuck in the joint of the flask: heat up the joint with a bunsen burner from all sides for a few seconds. The glass expands and in a lot of cases you can easily twist off the stopper. Your hair dryer might also do the trick, if you heat up the glass for a while longer! Has saved the lives of countless round bottom flasks when I was in the lab...
I always worry I'll crack the flask and then the flammable liquid inside will catch fire and it'll all end in disaster... Haha i'm overthinking it for sure though
I don't understand 99% of the stuff in your videos but they are still some of the most entertaining content here on youtube. I guess I just enjoy watching some random Aussie synthesizing explosives in a shed in his backyard!
If you have several options, and one of the options uses the caveat 'stupidly powerful', that is ALWAYS the option to choose.
It's soooo good to get some new content from you! Excited to see how this shapes up.
"i got a lot of comments of people that hate that so im gonna continue doing that" golden
I really liked the segment before the end when you went in detail on which UV tool you are going to use. Keep up the awesome content! Glad to have you back!!
Woot, I wasn't expecting this what an early birthday present : D
Also, I wasn't expecting the product to be that pure and selective....I sense something terrible happening
Dude. Video quality is on point. Glad to see you again.
Just a day ago i watched your old videos for fun and feels and you posted new one. Thx mate
One kind of cheap way to get a lot of relatively pure UV light could be to stack different spectrum filters on a lens and use sunlight.
Bruh I'm traumatized af from ultrasonic baths, the amount of times I held an NMR tube inside to "quickly dissolve" my big boi ligands and it just spewing everywhere from a small amount of residual gas in the d-solvents fml
This channel is gonna blow up, keep up the good work man!
So glad to hear the enemahr proved you have more than just 🎉🎉TAR!🎉🎉
Hell yeah bro, glad to see you back and posting again!!
That focus depth, so cinematic. I like the new camera.
So much love!! Thx for the amazing vid
80%+ yield! I followed this series from start, and can't express my delight. Had to rewatch the nmr bit right away. All those points of likely failure on the way circumvented, bless you mate well done! (:
"I gotta stop overthinking this!"
Story of my life brother cheers
Been rewatching this in anticipation. Love this project.
I really like the new camera and video improvements! That was definitely a worthwhile investment.
Mate, I know nothing about chemistry, but love your videos. So thanks for sparking the fascination with it all!
Ah fuck I think I almost learned something
apologies
Return of the king. Glad to see you again.
At first I thought you were standing in front of a green screen but then I realized it's just the enormous jump in footage quality and focus.
Glad to see more videos again from you.......ignore people that complain about your personal idiosyncrasies for they are not chemists obviously
Legend! Love that you did some NMRs
Man it's damn good to see you back, damn youtube didn't notify me at all so I'm a few days late. Watched the other video too, hope everything goes well with your thesis too
Thank you!! Is great fun to be back posting videos again
Lol I'm just waking up for work to a new vid. Thanks for being on the bottom of the earth
I don't even know why I watch this channel it makes almost no sense to me but I love it. Welcome back!
I don’t know whether to be impressed or jealous of you for getting better yields in a shed than I get in a uni lab
I wish my yields in the real labs I've worked in were this good. It's the magic of the shed I reckon
so happy to see you back :,)
Lots of discussion about the UV band pass properties of borosilicate glass here. The physics department changed you, man. For shame.
Damn it is good to have you back. And I think the reptile UV lamp might be as good of a shout as you can do in off the shelf inexpensive equipment.
Haha yeah I spend most of my research caring about emission spectra and absorption properties of things like filters... I think it shows too much in this video
@@ExtractionsAndIre Hell, I'm an experimental aerodynamicist by trade, I'm guilty of physics myself here. Although most of my job seems to be explaining to people that obvious measurement errors in data aren't real and shouldn't be treated as gospel data. *grumble grumble*
Congrats on your enemar results!!
There are very cheap nail salon UV lamps that we use to cure UV glue and work very well, if you need a backup suggestion. Happy you’re back!
Rouge pet care person who was going to suggest that you might be able to use a reptile lamp. The animals use it to metabolize calcium, for those who were wondering. Very important, especially while they’re growing.
Also, that kind of UVB bulb really doesn’t get super hot when it runs for a long time. It’s not for heat, just UVB. You can run it for 12 hours and unscrew it like 30 seconds after you turn it off.
So glad to see you. Hope things are well
I used to think you were just an Aussie hack, but now I realize you're a lucky Aussie hack.
Congrats man
Bravo on a successful synthesis!
"Fahkin' Emetchah!" Why is your accent so perfect for your content 😂
For the UV lamps, a used 400w High pressure Hg might work ok. They are getting replaced with LEDs in industrial buildings, so ebay and such _should_ be full of them. Normally they shield the UV with an outer glass envelope, but you can cut/break that off and get unfiltered output from it which will give you sunburn in like a minute (ask me how I know lol). It does expose mains voltage parts, but then you wouldn't want to be near it when it's on anyway.
You'd also need a ballast to run it. Depending on how sketchy you want to do this, you could just buy an E40 400w HQL bulb on its own and wire some incandescent light bulbs in series. Or buy a proper fixture with everything included. I got a proper fixture and bulb for like 40€ a while ago, but then I'm not in Australia..
Search for "HQL" and watch out that you dont get a "HPI" lamp instead which look identical.
I needed this today
Holy fack it's the cubane episode for the decade, welcome back
Glad to have you back with us. Now... install your updates. Yours Sincerely, Your Friendly Neighborhood IT Engineer
I dont know why but the confetti when you said Tar i laughed super hard lol thanks for indirectly making my day
I love watching these