016 - Could a fecal transfer abolish your chronic pain and fatigue?
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- čas přidán 12. 05. 2024
- A new study suggests that fecal microbiota transplantation (FMT) can significantly reduce fibromyalgia pain, fatigue, and mood problems. I want to share what I think about the study, and what needs to happen next. The link to the paper is below. I don't think the complete paper is open-access, but if you search the title with Google, you may find it posted somewhere. - Jarred Younger
pubmed.ncbi.nlm.nih.gov/38663... - Věda a technologie
Dr Jared Younger: “ This is really quite an interesting study. “
Me: “ 😳 🤯 🤯 😳”
I would think the real difficulty in the current state of the world would be to find donors with a truly healthy gut biome.
I didn't even think about their part of it until now! - Jarred Younger
I believe there’s already at least one company in the US that produces fecal transplant capsules from approved donors - it is a nonprofit created by MIT researchers, called OpenBiome. Their web site says these oral capsules have been used in research clinical trials, as well as for C. difficile treatment.
I would love to try FMT. My me/cfs and chronic pain always is much better after I take antibiotics, which I’ve needed to do quite a few times over the past 30 years. I was a subject in the Jackson Labs study that included fecal microbiome testing, but unfortunately I haven’t been able to figure out what probiotics might help to restore my gut microbiome.
Import samples from Bali etc, where everyone is stress-free and eats fresh,healthy foods.
Especially unvaxxed.
@@roxyiconoclastdo you have hypomobility I've had CFS 27 years fybromyalgia 6 found out I have autism ADHD causation
Very interesting to see this, unfortunately I do not have experience with Fibro and FMT. I still feel like I should chime in. I tested 50+ potential donors and helped many dozens people do FMT in Barcelona ES (probably a dozen with CFS/ME). My anecdotal result is that the gut dysbiosis is clearly A CONSEQUENCE of disease processes. However, improving the microbiota mostly improved the disease state, unfortunately the effects are mostly temporary, noting that sometimes the homestatic level is improved in the longer run after the therapy. So, yes FMT can make sense, I say, in particular if you have tried it all and/or you have access to FMT material from a healthy individual with an overlap in genetics and environment, but don't think it is the end all be all, it is NOT a cure, at lease I have never seen it be one. It can be very helpful. Good luck.
I appreciate the great perspective! I agree I was most surprised by how the symptom timecourse differed so much from what I've seen reported before in FMT trials (with only transient improvement). I'm still not quite sure what to make of the results in this paper. I really need to see the independent replication. - Jarred Younger
@@youngerlab yes, agreed
Yes and I know somebody who had it done and it changed their life.
Oh wow great! What condition did that person have and how did it change their life?
Thank you for posting this, Dr Younger. For what it's worth, I had FMT (from a clinic in the United Kingdom) and it did nothing for my ME/CFS. Nada. However, I didn't take any antibiotics prior to the transplants, and perhaps that was why it didn't work.
FMT is highly dependent on donor quality. Most sources don't bother putting in effort to find highly effective donors, especially due to how rare they are.
Vielen Dank dass sie so unermüdlich weitermachen. ❤
Wir brauchen dringend jede dieser Hilfen .
Grüße aus Österreich
I remember one guy doing massive research on this in a CFS forum. The donor was really important and he said he had the best results with young healthy university athletes' feces. He has quite the story along with the type of donor to avoid.
Probably me :)
People can look up "human microbiome forum" if they're interested.
Wow my rheumatologist at UCSD just told me she thought this might the ticket to helping many with fibromyalgia and similar conditions (Dr Katherine Nguyen)
The paper is not publicly accessible, if anyone needs it you can probably get it accessing through a Uni library PC. Or shoot me a msg, I can send it to you.
Thanks! I wish everyone did the open-access model, especially for treatment studies, but I understand the $3000-$4000 fee can be too much. - Jarred Younger
I am going to try this soon for fluoroquinolone toxicity. I'm a former pharmaceutical rep who became disabled from Levaquin. There are tens of thousands of us on the online support groups.
I've heard of many individual success stories with Fecal transplants for ME/CFS, but regulatory restrictions keep it from being an available treatment from what I understood. Has anyone heard of this?
AFAIK at the present time FMT is only approved for C diff infection here in the US. There have been deaths after FMT so regulators are cautious (overly so IMO). It reminds me of what happened with gene therapy after there was a tragic death in a trial in 1999.
Dr Cheney has gone on record to say that while CFS and FM may present similarly, CFS is a different beast altogether. His FM patients would improve from exercise while CFS ones would crumble, for instance. That one simple fact would suggest an entirely different pathology.
Really looking forward to the UK study completion. Should give us a good quality decent study to give us firmer answers on this, and that's about time (as with all ME treatment studies), it's good to see some things getting crossed off the list now - ruling things in or out with greater level of certainty.
Bad gut microbes and/or parasites retreat into intestinal biofilms when their under attack by antimicrobials, antibiotics or even just foods that they don't like. These intestinal biofilms make a lot of the bad gut microbes/parasites antibiotic resistant. So don't forget to take into account 'biofilms'
I started taking a different approach to some of the issues I was having due to Chronic Myelogenous Leukemia, FM, around 3 yrs ago. Using Fulvic Acid powder in a soak only. Some people drank it in their coffee. It was banned by the FDA but I still used it to soak in as I had a viral plantars wart on my foot, and several odd looking black holes in the pad of my feet that when I tried to pull out , they retreated only to appear again. Fulvic is a known “ anti parasitic “ ( I put a tad in my dogs water bowl and he expelled worms) after months of soaking or using a face mask my feet healed completely. I also make note that my CML PCR trend went from -1.07 to -3.67 over this period. Which means I gained a deeper remission CML wise. When I could not get any more of the powder, my plantar wart is back full bore and I feel horrible. I just recently reordered as it is back on market but not labeled “ for consumption.” Idk if this is significant at all.
Fenbendazole may help with that issue.
I believe Lumbrokinase has been shown to dissolve biofilm. Canada RNA claims to be the best brand. Idk.
1 simple infusion will do nothing, specially if you have been sick for years and you are using a bad quality donor. Donor is key in Fecal Transplantation. I have been able to recover around 50-60% (unfortunately not fully healed) with many FMT enemas, castor oil packs and neural retraining. I will start a new round of FMT in September and plan to be doing it for 3-4 months.
Prof Younger, could you please start putting the date of recording in the you tube title because the site doesnt show this clearly. thank you.
There's an FMT group on Facebook where people experiment on their own.. 🙈 I joined it but I couldn't stomach the idea.. It's so so gross.
Yeah, I'm going to say wait until it is an accepted medical therapy! They typically use sedation to make the process bearable. - Jarred Younger
If studies show that this works for ME/CFS I would 💯 to get my life back!! Housebound is not a life.
Donor is the most important factor in FMT, that's why studies will not be useful for this, donor and compatibility seem to be the key factor, I have used a few donors and only one of them has been really helpful for me.
This sounds like a breakthrough in FM treatment. Unfortunately, I had rheumatic fever in childhood and require antibiotics prior to routine dental work, such as cleaning, so it wouldn't be an option for me.
I gave Over the counter probiotics to my mother. She has had gastric issues for most of her life, so I thought that probiotics might be a good idea, especially since she has had repeat doses of antibiotics at the hospital. I asked her doctor if it might be a good idea and he said yes. ……. She had to be rushed to the hospital again, this time with sepsis. The doctors say it had a GI tract origin. I will never know whether the probiotics that I gave to her definitely caused it, but I’m no longer enthusiastic about that approach. At least not for her. I think that if fecal transplants were standardized 20 years ago for a number of conditions aside from C diff, she might’ve been able to benefit. I am afraid to do anything now. I’m watching this series of videos to potentially help myself and family.
I wonder if probiotics in capsules are dramatically more concentrated than in feces. Like the concentration of an active ingredient in a supplement pill may be a thousand times that in the herb. For example curcumin pills vs turmeric.
Probiotic yogurt...
Some strains of probiotics raise histamine levels. After dental work I took antibiotics and got a terrible rash. Red blotches all over except my face and super itchy-this was a histamine reaction. So I took probiotics, but had problems. Then I found out that some strains of probiotics raise histamine levels (some more than others). There are some strains that don’t and supposedly some strains can counteract the histamine caused by others. You can google what strains don’t raise histamine if that’s an issue..
One point which actually has nothing to do with this very interesting study… I am a board-certified lactation consultant …and I know how profoundly damaging it is to interfere with the lining of the gut with colostrum in the newborn infant. Well intention but uninformed medical staff often give water or formula to “let the mother rest” or other unscientific reasons.
Second point : I’m very curious as to what criteria is used to be a fecal sample donor? I’ve often thought I would qualify as I eat a diet rich in fermented foods
* My ME started in 1996 after a long term systemic yeast problem that caused leaky gut syndrome. I was successful in reversing that through fermented foods. But that does not appear to have had any effect whatsoever on my ME.
The list of criteria for the donor is quite long (it is a page long in the paper). The donor has to be perfectly healthy and pass a number of additional tests. In this study, they used only two donors for all the patients. Maybe it is hard to find people who meet all the criteria. - Jarred Younger
Fermented foods can be horrible for people with raging mast cell problems and histamine intolerance. Colostrum supplements can be the completely wrong thing for people with very high secretory IgA. Colostrum can increase SIgA.
@@youngerlab My idea is to pay people to be professional donors. They would live near the facility and their job is to eat healthy food and go in to 'make a deposit' each day. $500k per year salary - works out to only $1370 per 'deposit' - that's less than the cost of 2 tubes of Eucrisa!. This would be an excellent 2nd career for a family member of mine who is enviably healthy.
Thank You for Sharing your knowledge and your experience. Thank you for all your great work.
Another possible big confounding factor is the use of antibiotics before the FMT. My colleagues at Renegade Research are doing a "Remission Biome" experiment where there is a remission after antibiotics help reset the system. They are in the middle of their second phase with 50 people. Tess and Isabel will probably present the single-cell data from Tess's remission induced by antibiotics at the Unite to Fight conference this week.
My biggest bump in baseline came from 2 antibiotics during diverticulitis. Like Nicotine Patches, it is not a cure, but results can last and benefits are important.
Just want to mention that some antibiotics can have other effects besides being antimicrobial. For example, doxycycline is anti-inflammatory and minocycline inhibits mTOR and was shown to be protective against TBI in rats.
I have ME/CFS, I tried this by travelling out of the U.S. to a clinic after reading a study by Dr Borody that pointed to potential amelioration of symptoms.
May have helped GI a touch, but it certainly did not fix my PEM, neurocognitive, etc. (and I don’t have CCI issues). No duloxetine involved.
Maybe this is a FM thing and not an ME/CFS issue.
I do feel that creating a healthy microbiome should be standard care.
Interesting..... wow... definitely different but i believe something natural is better than pharmaceutical.
Tq for sharing 🎉😊
I would do it and to help with both disorders I am diagnosed with and my AuDHD.
Some probiotics (gut bacteria) can actually raise histamine, some more than others, and some don’t. Histamine rising in the body is an allergic response from what I understand.
I agree with others questioning what “healthy” means as far as donors go. I’d want to know how they’re screened, and if that can be somehow confirmed/disclosed-transparency. I also wonder if this can evolve to isolating the organisms from the fecal matter. Someone will probably want to do this. But then maybe it’s not just about the good bugs but certain co-factors; some interrelated symbiosis with other stuff in the terrain going on, so you’d lose something that’s effective with these good bugs isolating them. I’m talking about some body chemistry not necessarily the body’s probiotic terrain. What do you think Jared? And many thanks for you’re contributions, ongoing interest and research with these miserable illness’s.
I have mast cell, so I do t break down histamine in food, my body doesn't produce the enzymes. I do believe it's partly because of my gut, as when I was following a modified SCD , GAPs diet for 6 months, then went back to my healthy eating. It seemed I was having g no more problems. Until the shutdown hit, I lost my good PT gig, started eating candy and cookies I'd never eaten before, became homeless, and can only eat what I get now. The histamine reaction and everything else has doubled and tripled in intensity
This is exactly why I haven’t done it.
Very good points. I wish I could share the paper -- the screening criteria for the donors were quite comprehensive. Most healthy people probably wouldn't pass. It looks like they could find only two individuals and used those two for the entire study! It is possible that different healthy donors would have different effects on recipients, but I haven't seen that tested. Like custom "cocktails". - Jarred Younger
Sounds very promising. I didn’t know they needed to wipe out the gut microbes prior to transplant - but it makes sense. Thank you!! 😎❤️
I've been open to the idea for 15 years but never came across a practitioner who would fascilitate the process. It seemed only to be considered for chronic diarreah.
And I never could get myself to DIY it.
However I would much much rather first do it without taking antibiotics.
Maybe afterwards if that felt ok and wasn't effective I'd consider taking antibiotics.
I'm guessing the fear with FMT minus antibiotics is that the resident bacteria would win out versus the introduced sample. And I will just go on the record and tell everyone not to go the DIY route! The criteria used to verify the appropriateness of the sample and process is much more involved than most people would expect. Thanks! - Jarred Younger
First, love the artwork behind you.
Given the standard diet these days, I wonder if the number of healthy donors may be decreasing. It’s difficult to be patient, wait for results of the studies. I want to try every new idea. I crashed hard last week, and with that comes the depression. I want my old body back!
Have both fibro + sibo/gut dysbiosis..long civid made all worse..absolutely, need firward movement asap..give dies nothing, +my drs dont know what im talking about..living w daily chronic pain is debilitating , a living hell.
Healing the gut, is a long slow process..now have developed food sensitivities, hi histamine, low fodmap, difficult + pricey..was pre med, so aware of gut amino acidd, enzymes, antifungals..open to and resources, USA, a gut info would be helpful , esp w long covid .i try to avoid rx, go herbal whenever possible, tu..appreciate all u are + do 🙏💞
I have questions too. Like, why did it continue to improve? Gut biome tends to worsen over time, not improve. Mine surely does without the dietary adjustments.
Possibly, the drug is of a great influence here. Or diet. What diet did they use?
That is a good question.
This is an aspect where modern use of strong antibiotics, even when necessary is impacting a person's natural gut biome. If shortly after an intense or even just mild viral infection at a particular vulnerable time then leads possibly to a cascade in the body to a post viral syndrome cascade. Aka, CFS/ME/FM/LC.
With this study, it would be good to see a follow up by that team over following two years to see if this was a permanent significant moderation or recovery from FM.
(On your comments reading research, that is exactly how I do it. And depending, then read through it to check the details. And yes, if it is too good, that is something I note also. Been watching research for 40 years! )
I did this at a private clinic in the UK. I had 10 FMT treatments from a variety of screened donors. I didn't help me unfortunately. Obviously I had no way to quality control the clinic so who knows what exactly I received...
Intersting are you hypermobile heds
Wow.. interesting
Very interesting. My first reaction looking at the diagram was that Duloxetine only group seemed to react too quickly to medication? Wouldn't it typically take longer to see improvement with this SNRI?
I’ve listened to a few of the Zoe podcasts, which makes me think this could only be temporary without wider dietary changes. Perhaps working on improving the gut biome is a simpler way to help? 🤔
Can you recommend a physician in the Raleigh Durham Chapel Hill area of NC. I am willing to try non-traditional treatments.
For fibromyalgia? There's a mainstream doctor at Duke named E. William St Clair; it's very difficult to get an appt. Most of the doctors around here are biopsychosocial types ('Yes, of course your pain is real. Here's an Rx for an antidepressant and a referral to a therapist. Have a nice day. Bye'.) There's the 'mold doctor' (and tea sommelier!) Dr Sonia Rappaport. She charges lots and there's no guarantee you'll get rid of your mold or your pain, but she has reportedly helped some people. If you have ME/CFS there's the Hunter-Hopkins Center in Charlotte; I've thought about taking my daughter there (she has ME symptoms). They don't take insurance (like Rappaport) and the initial appt takes several hours - so for us, that would mean an overnight stay. They would not tell me if they do CPET for some reason - they make that decision after an initial exam I guess. I've thought about trying Carolina Total Wellness. Again, lots of $$$ and I don't know if they can actually help me. IIRC they require that you already have a regular primary care doctor (this is the case for many functional doctors). I've mostly managed my chronic pain on my own so far. I get my LDN Rx online from AgelessRx. If you find a good doctor, please post.
I remember hearing a long time ago of the use of this treatment in case of intractable diarrhea, and being so impressed. Later on, I wondered why something like that was not done routinely after a course of antibiotics which wipes out all your guts microbes. It leaves to chance which bugs will the fastest to recover and could some bad guys not take over, mafia like. But I realize that it would be too costly and would be difficult to find enough healthy doners. But cannot the most beneficial bugs be grown and kept alive in labs? I have an inkling that to start colonies would mean at the minimum, knowing how to feed them. Probably those livings organisms may be too complex to turn into some sort of pets. LOL Anyway, the research you mentioned is exciting, especially when, if I understand a little bit, that the guts bugs have a major influence/control over the brain functions. Thank you. Pierrette
I had to look into it after I did the video, and I see there are groups working on various ways to for FMT without the donor. There are artificial stool samples. And one person in the comments above mentioned an oral substitute. They both involve real bacteria, but cultured in the lab without needing human donors. It makes good sense to me to use these approaches, but I'd have to hear what my colleagues doing this work say about those newer products. Someone would have to run a trial with them and see if they work as well as the 'real thing'. - Jarred Younger
@@youngerlab Good to hear. Thanks for responding.
I was initially very enthusiastic ten years ago when I heard about the resounding success c-diff patients had using this therapy. For some reason I lost hope for this type of treatment I can't remember why. You would think an official study would have been conducted 10 or 15 years ago when it was recognized how well it worked for patients with c-dff.
My understanding is that FMT for c-diff is on solid ground and works well for the majority of patients. The reasons it wasn't tested in chronic pain and fatigue back then are: 1) the people using it originally were gastrointestinal experts who weren't interested in brain inflammation, and 2) it wasn't fully appreciated 10 years ago how impactful the gut was on the brain. - Jarred Younger
Would it be possible to make synthetic poo? I realise they have many microbial components. However, a synthetic one would be safe and contain the particularly good microbes (once we know what they are). Just a silly idea from a science enthusiast with ME……..
Dr Younger, do you know whether the subjects were required to change their diets during the study? I wonder how much improvement can be made just with a healthier diet alone? And whether the improvements can be effected by the patient's lifestyle /diet changes after completing their treatment phase.
Dr Younger, I would like to do MR spectroscopy of the brain in my country, similar to what you did for patients in your study 5 years ago. What should I tell my doctor or MRI specialist so that they understand what is needed? Can you provide some kind of protocol?
Hi. The neuroinflammatory scans are too experimental for hospitals/clinics to run. There are only 5-10 groups worldwide that can do that scan. The only way to find it is to search for universities that do MRI and PET neuroimaging work. If you search for MRI or PET neuroinflammation in your country, a team might come up in the results. Another scan that is useful is called TSPO (translocator protein) microglia scan. There might be a medical research team using that scan. Good luck! - Jarred Younger
Just wondering does the FMT transfer happens once or several transfers?
It was just once in this study. I have heard of protocols where it is done every few months. - Jarred Younger
Great info! I’m wondering if it would cause the positive effects of the FMT to last much longer (or even forever) if the test subject committed to adopting the same lifestyle of eating as the FMC donor.
Yeah I wouldn't expect the intervention to last long without committing to significant lifestyle/dietary changes. It seems that good donors are hard to find. - Jarred Younger
Very interesting because what I have is genetic but causes IBS certainly I have heard of it and have had to deal with pts with C-Diff. I personally take high refrigerated probiotics and prebiotics and think that our diet as we used to say “ we are what we eat.” Maybe the use of both interventions would help some or many. I would want to know the donor, even though it is washed. I would definitely want to see more studies and if they received their FMT from others with CF. For all their pts to say that their pain is a 7 all the time is a bit questionable. Yes independent groups need to test with and w/o diloxitine. Thank you. I certainly believe the brain gut connection and maybe the specific bacteria can be isolated to find out for the future it’s effects on the microglia. I certainly think that would be a worthwhile study to have the FMT donor bacteria checked and isolated. It seems the more our food chain is affected and other choices are taken the more our health is affected but I am certainly not saying that it is the cause of all these diseases.😊
Hi Jarrod. Have you read any of the research on Grounding mats? After 3 weeks my pain has decreased, brain stem inflammation has decreased, my sleep has become deeper, my brain fog has virtually gone, and my bowel movements have become normal (after years of not being normal).
Do you have a local clinical trial for chronic fatigue?... im not officially "diagnosed"... but have been severely fatigued for more than 3 years. Tq for your reply.❤ i am a UAB patient and former employee
I heard Elaine Colby, MD sees ME/CFS patients in this area, but I have not spoken with her. I don't think she is part of the UAB medical system. - Jarred Younger
I my own case I developed food intolerances (wheat, soy, all common spices, etc etc) when I was 16. Three years later I developed CFS and a little later FM. Both CFS and FM went mostly into remission after about 3 years. I eventually figured out my food intolerances and stopped eating anything I react to. A few years after that CFS and FM returned and I've been disabled ever since.
This treatment seems great in theory... And might fix my food intolerances? But in my case at least it seems unrelated to my CFS symptoms and since things like IBS are highly common in autism and other diseases I would lean more towards this being a symptom of something rather than a cause. Just my 2¢
I have autism fybromyalgia CFS heds have you tryed ldn it helps fatigue but not pain for me
Hi Jared,
There are some case reports of stellate ganglion blocks successfully sustaining long term remission of idiopathic cases of trigeminal neuralgia and central post stroke pain popping up in the literature. I am also aware of one woman who claim's she was put into complete remission of Fibro and CPTSD for 9 months following two SGB injections, and when the condition returned, once again achieving sustained remission since September 2023 with two additional injections. This is something that I think warrants further investigation. Are you aware of any bodies investigating its use?
Thanks again,
Dr. Younger, the paper is not open access. 😮💨
I'm wondering what these people might experience if they require antibiotics, post treatment? Also, are there any known US researchers working on this? Finally, is your co-research counterpart in the UK going to analyze glial cell status, post treatment? And what bacteria do you think may be the most important?
I don't know anyone in the U.S. right now using FMT for chronic pain or fatigue. The U.K. group just has a fairly small non-profit pilot grant, so they won't have the money to do glia imaging. If they have results as impressive as the fibromyalgia paper, I may get involved at that point and add my neuroinflammation imaging to definitely show if FMT works by calming microglia. - Jarred Younger
Do they kill viruses and fungi as well as bacteria?
Certainly fungal, but I don't know about viral. I don't know of anyone who has looked at FMT impact on viruses. - Jarred Younger
If anything the power of stomach bacteria will be studied. Apparently cicada have unique bacteria strains, will be in my diet as soon as they are out!!!!
Eating cicadas?
Wow, how do you prepare them and which bacteria strains or what's your goal?
So this would mean fibro is a gut issue?
It would mean that, and I'm definitely not at a point to adopt that view. It would be a significant shift in our approach. I can see GI issues being a major trigger for a subgroup of individuals with FM. - Jarred Younger
@@youngerlab I think identifying subgroups is key to treating fibromyalgia.
I did this last year, it really helps with gi issues but did not help with whatever the hell is going on.
It's heavily dependent on donor quality, and high-quality donors are very rare.
Nothing is 100%. Did you have all your gut bacteria killed off first?
@@jas340 I did a week of two different antibiotics, prior to it I had lost 30 kilos in 8 months, I stopped losing weight so it definitely did something.
The lack of a control is concerning. Perhaps the bowel prep had some effect?
Well, I wanna get a fecal microbiota transplant.
Didn't work for me.
Can you elaborate?
I would love to try thos because I feel a connection between bowel symptoms and cfs neurologucal symptoms.
So frustrating that they don't fund large studies
If the UK study turns up good results, I bet money will become available for a larger trial. The funders will want to see just a bit more evidence that it is likely to work first. - Jarred Younger
Dueloxetine is a horrible drug. I would never take it.
*again
There is definitely a significant group of people who can't take it or find it isn't worth the benefits. That's another reason why I would have liked to see the FMT tested without the duloxetine. - Jarred Younger
@@youngerlab Thanks for replying Jarred. Be interesting to know who! It did help. It completely ridded me of awful shoulder and much of the muscular skeletal pain *for a while, but it did come back which is why I stopped taking it. It was really horrible to start and really horrible to stop taking and I have had thoughts about long term effects as with similar drugs, although I know it isn’t a benzo but I have read about it having a similar effect to it. Nothing like the dream LDN was. I am generally much more unwell now because of MCAS anyway. I’d love to be as sick as I was then 😂
Looking forward to updates on everything else you are doing. As always, huge thanks for all you do and really hope you visit the conference in the UK this year. I would love to get on the FMT trial but I live too far away. Dr Myhill has done a DIY version for years I expect you are aware of, but I never fancied trying that!
What is DIY version do you have fybromyalgia heds
Would I try FMT? As Fry from Futurama would say - "Shut up and take my money!"
I already have to spend all of my working life absorbing other people’s s**t.
Wait is this real? I thought this was just a South Park thing
It's real and there have been really interesting/promising results from preclinical and also human trials for various conditions, e.g. Parkinson's - even aging; right now it is only approved in the US for the treatment of C. diff infection, which can be life threatening. You'll see a lot of comments here from people saying they did FMT through private clinics, but they don't say what type. It can be done through oral capsules (aka 'crapsules'), colonoscopy, enema, or nasogastric (NG) tube. The colonoscopy type seems to be more effective - or at least it was in a clinical trial for Parkinson's which compared colonoscopy delivery vs NG tube ('Fecal microbiota transplantation therapy for Parkinson's disease: A preliminary study'). The origin of FMT goes back to 4th century China where patients were given 'yellow soup'. I would not do 'yellow soup', but I would try an FDA approved colonoscopy FMT for fibro or eczema if it were available.
No thanks. I cured my 15 year journey with severe ME/CFS that left me bed ridden and housebound. My condition lifted somewhat when I started eating ketogenic diet. Finally in 2023 I jumped into carnivore and within weeks my fatigue and brain fog lifted. Over time my joints and random pains have all gone. I no longer have migraines that have plagued me for most of my adult life and many other chronic conditions have healed over time.
Best of all I have lost 4 stone without ever being hungry or really trying.
That does suggest it's the gut. A round of FMT can easier and cheaper than carnivore diet for some people. Good to have options and glad to hear you found a solution.
Hello, How long do you have to be on this carnivore diet for?
Nothing but meat or anything else?
@@SIRIUS3540 Some people eat just beef, eggs, butter and water but tbh that's a bit extreme for me and wasn't necessary for me to heal. I simply have a mix of steaks, beefburgers (no bun!) belly pork, all roasted meats, poultry and game meats. I eat a lot of eggs - boiled, scrambled, omelettes and fried in butter. Cheese omelettes are a good standby. I DO sometimes have some blueberries (or other berries)with extra thick double cream and I have double cream in my coffee but generally avoid fruits.
It sounds restrictive but honestly if you had been bed ridden with ME/CFS you will understand why I don't want to risk going back to that and there is no other treatment that has worked for me.
I started noticing some fatigue and brain fog lifting quite quickly on ketogenic. But the carnivore diet was a complete life changer though - everything else disappeared in weeks/months. I still feel as though long term issues are still healing.
(Please note I am not anti-plant based or any other diet. We should support anybody who finds a good way to manage their health without being judgemental)
@@MichaelMerritt I adopted the carnivore diet because people with ME/CFS need to feed the mitochondria in their cells (including nerve cells) and allow the compromised myelin sheath on our nerve comnections to repair with good healthy saturated fats and protein. As do many other conditions such as MS, autism, epilepsy, etc.
I'm not disputing good gut health but I don't think that was the answer for me.
@@gwynhyfer I appreciate your detailed response. And that makes sense!
I heard: ‘Trapped for twelve months’ 😅😂
No
Sounds a right load of keech to me.
That sounds totally disgusting 😒
Indeed. But if it can help people, it’s wonderful! 😊
Yeah, But I would enjoy it.
Feeling sick all day is way worse 😢