Probing Principles of Genome Organization and Function - Bas van Steensel

The lab of Bas van Steensel at Netherlands Cancer Institute develops and applies new genomics technologies to elucidate principles of gene regulation in mammalian cells. In this seminar he discusses an approach to efficiently alter the linear structure of a large genomic locus in a highly multiplexed manner and study the impact of these perturbations on gene regulation and spatial chromatin organization.
The Monthly Seminar on Physical Genomics is a public lecture series sponsored by the Center for Physical Genomics at Northwestern University, the Robert H. Lurie Comprehensive Cancer Center, and NIH Grants T32GM142604 and U54CA268084. CPGE's (growing) archive of public seminars and talks can be found at:
physicalgenomics.northwestern...