Resveratrol: dosage and effect on cardiovascular health | David Sinclair
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- čas přidán 3. 12. 2019
- Over the past few decades, an abundance of scientific research has focused on resveratrol, a plant-based compound found in red grapes and peanuts. Much of this research has demonstrated that, at high doses, resveratrol exerts beneficial health effects - especially on the cardiovascular system - and has been shown to ameliorate the deleterious effects of an obesogenic diet in monkeys. Resveratrol is a "dirty molecule," however, known for its multiple cellular targets, so teasing out all the ramifications of its use has proven problematic. Furthermore, it is relatively unstable and demonstrates poor bioavailability in humans. In this clip, Dr. David Sinclair identifies some of the practical considerations of resveratrol supplementation and discusses his personal use of the compound.
This clip was taken from the FoundMyFitness interview with Dr. David Sinclair found at • Dr. David Sinclair on ...
Original episode published on Nov 6, 2019
⏳ #Aging #Resveratrol #Epigenetics 🧬
About FoundMyFitness: Rhonda Patrick has a Ph.D. in biomedical science from the University of Tennessee Health Science Center, and St. Jude Children’s Research Hospital. She also has a Bachelor’s of Science degree in biochemistry/chemistry from the University of California. She has done extensive research on aging, cancer, and nutrition.
It is Dr. Patrick’s goal to challenge the status quo and encourage the wider public to think about health and longevity using a proactive, preventative approach.
Learn more about Dr. Rhonda Patrick and her mission for FoundMyFitness at www.foundmyfitness.com
About David Sinclair: David A. Sinclair, PhD, is a professor in the Department of Genetics at Harvard Medical School and co-director of the Paul F. Glenn Center for the Biological Mechanisms of Aging. He is the co-founder of the journal Aging, where he serves as co-chief editor. His work on aging has earned him numerous awards for his research, including the Australian Medical Research Medal, and landed him a spot in Time magazine's Top 100 most influential people on the planet. Learn more about David Sinclair at sinclair.hms.harvard.edu/peop... - Věda a technologie
Watch the full episode:
czcams.com/video/5DtWqzalEnc/video.html
FoundMyFitness episode page:
www.foundmyfitness.com/episodes/david-sinclair
More clips from this guest:
czcams.com/play/PLrGxo-5Uw8gIMoEAG-62qQNA7xfiTcQZu.html
It would be great to know where he gets his resveratrol. I cut my trunature resveratrol pill in half, and it was brown inside.
Dear Doc. I had endometriosis when I was young. Now no more bcos of old age. Is it ok for me to take it. For now I take transresveratoral 350mg every other day. It seems to help a lot with my stomach and gastric pain. Need your advice please.
@@ParallaxView111
Shaklee would be my guess…he developed their resveratrol product.
@@michholl2 thank you. I will look into that.
Dr Patrick is positively prolific. Hugely influential! She’s everywhere. David Sinclair is a genius. Definitely recommend his books.
I think she might be crushing.
@@purpleduck3494 what do you mean?
Did you watch this video? czcams.com/video/JAFnD27ffqE/video.html
Na she just being passionate l would feel the same.
Not sure how well humans will do on all this resesrch, but mice are gonna be living for decades.
You've seen "Rise of the Planet of the Apes"..... well it's actually a mouse rising.
🤓👍
Hahahaha
Pinky & The Brain approved.
😂😂
The David Sinclair that is trying to stop all of us (by using the FDA) from being able to purchase NMN is a genius and hero? The above is from 4 years ago and I think he has shown himself to be more than self serving since then.
Just started taking it this week on Tuesday. I had pain in my left side. It came from my lumbar spine. I'm 75 so it will degenerate some causing pain on my left side. I do the physical therapy for that. Well I had some eye problems and the eye doctor suggested berries in my diet. On Tuesday the eye doctor suggested reveratrol. I'm a former marine so I'm obedient. I started taking it and you won't believe what has happened. The pain on my right side is gone. I mean I played ball with my grandson for a hour and no pain. I then got in the car and no pain when I sit down. No pain at night either. This was for my eyes and not my lumbar. In 3 months I go back to the eye doctor. I wonder what changes will occur then in my eyes. I hope there are no bad side affects.
So glad I came across this. I’ve been taking brown Reservatrol Pills on an empty stomach because the bottle said it was ok & storing the bottle near sunlight in my window. Will try to find non-brown Reservatrol, store it in a dark place, and ingest it w/ fat. Thank you.
czcams.com/video/nXC9W7st9B4/video.html
Memo: Take resveratrol with fat, increases intake 5 to 10 fold, also it is light sensitive, keep it in the dark
but fat breaks a fast. i take it with black pepper.
What bout coconut oil? Fair enough it breaks a fast but it'll give your ketosis a boost
@@simon824 - coconut oil is hi in LDL (bad) cholesterol. So maybe look for a different fat?
What about mct oil?
What is a reputable high quality brand ?
I like this hopefully this suppliment can be bought in Sweden.
Resveratrol, Circumin, Fish Oil, Garlic, Vitamin D and a high quality multivitamin once every couple days is the perfect for me.
You’re perfect for me
@@tfries72 thanks lol
@@tfries72 😘
NOT THE FISH OIL THO
No Magnesium?
Just a heads up, this vid made me go over and look at the resveratrol capsules I had. Opened the bottle and ah white, good. Opened one up and it was actually brown powder in a whitish capsule. They aren't very old so be careful what you buy.
Do you know any good brand?
@@lightningandthunder2861 Not really but am pretty sure it's available in bulk, I think that's how I'd go.
Dr Patrick is so beautiful, her skin glows im taking her advice.
Sinclair is a hero!!
So is dr Patrick!
He’s full of shit - his research is now debunked
On two occasions resveratrol caused my wife to go into afib. Both visits to the emergency room. She did have a thyroid issue beforehand.
Need more data.
@@scottpreston5074 Her a fib was the result of hyper thyroid. She got on medication, had the nuclear thing for thyroid and everything was good. Maybe a year or two passes and I gave her resveratrol. She has afib and out of concern we go to the emergency room. Maybe another year goes by where I didn’t give her resveratrol at all And then forgetting about the hospital visit and pulling out all the supplements for her I gave her a resveratrol and she had afib again. Serious enough to go to the emergency room and then I put two and two together.
It has been suggested that resveratrol may actually prevent AFIB, so this is interesting. Are you still fairly sure this was the trigger? Did the resveratrol upset her stomach or make her nauseous (both known triggers)? Thanks.
@@JohnnyWoodard I don’t remember any complaint about nausea, but the two times in the last I think 4 years that she did go into afib I’m fairly certain it was the resveratrol. This was after she had the thyroid removal by radiation pill. I could be wrong, but I would not want to chance it again. But I stopped giving her resveratrol and she has never had another occurrence. And plus the whole longevity thing was debunked so . . .
@@nikolasbbq Thank you for bearing with my questions, but did she have it literally the day she started taking it? Or was this after it built up in her system? I know many people are taking this to actually PREVENT atrial fibrillation, so it *causing* it would be a real shock.
Why are we still not hearing about this. I want to try it.
I started taking resveratrol six days ago today. Solgar’s 100 mg capsules - I take 4. An immediate boost in energy and a sense of general well-being was the result. More importantly the anxiety spells I used to get throughout night sleep stopped! But I developed cold-like symptoms, thickened saliva and sudden mucus which led to a horrible sore throat - that only just started going away today. (Others have mentioned the fact - but in my case it was really bad.)
May I ask where you bought it? I’m trying to get some in the UK
Yes..thicker mucus and phlegmy felt obstructing the airways at the throat..I always feel the need to swallow saliva just to clean that area. Also frequently burping and farting..seems a lot of wind/gassy effect.
Correlation is not causation.
Please update and review research on the efficacy of resveratrol
czcams.com/video/nXC9W7st9B4/video.html
which product does he recommend.
I'm starting to take this, whenever I have money to buy it!
I was thinking about it, between nad+, resveratole, omega 3’s and probiotics etc, I can just take them every other day (but take resveratole and nad+ together they are synergistic). I just figure that at least cuts in half the cost.
@@DaveE99 Thanks for the tip!
@@DaveE99what is NAD ? Thanks
@@ebazileyes1475 just look up it up
Whats opinion from cardiologist on use of resveratrol on heart desease?
Most doctors have not done the studies these and many other specialists on the subject have done. Unfortunately, most doctors who don't have this knowledge will likely tell you it doesn't work or that they wouldn't recommend it. This is the sad but good truth about taking responsibility for your health by at least trying something different. After all, we're talking about a substance taken from grapes.
Can you please recommend a brand of resveratrol Dr. Rhonda?
where are the safe sources for resveritrol, NMN, etc.?
Keep in a cool, dark place.
Thanks for that. Bought some last week. Every 2~3 days. Extract of grapes.
His heart looks like it's 20 under the MRI and he's like 40 oh my god resveratrol is amazing dr. David Sinclair I will definitely buy resveratrol eventually and he eats a late lunch or dinner
He has one more meal a day. It may not be the resviratrol that improves his health but the other things he does.
He’s actually over 50 years old
He is 54 his father hike’s mountains
Why do some resveratrol say to take on empty stomach?
Would liposome encapsulation help with absorption?
Is not expensive.
Thoughts on micronized resveratrol sublingual?
What about liposomal resveratrol?
Great, I got rid of all my ennemies (mices & monkeys) with that. Positively prolific recipe Dr. Seriously :)
Minimum age recommendation for resveratrol?
Brand recommendation?
Look how good mr Sinclair looks
He looked ten years younger, ten years ago. You're looking at good hair genes and relatively low photodamage.
Nit sure if it s bc of taking resveratrol capsules tho
He looks 50 - which he is. As another poster said, he has good hair and limited sun damage.
A scientist might say that he is a n=1, but the lack of gray hair at his age is amazing unless he's coloring it.
bigbobabc123
He might have good hair, color wise, but he’s obviously thinning
Please, someone tell me the cheapest way to take reservatrol. My budget is pushed beyond limits with all the nutraceuticals i take for mito dysfunction.
I purchased Zhou brand trans resveratrol from The Vitamin Shoppe this morning. I clicked on this video to find out the best way to take it. My capsules are brown and I just broke the seal on the bottle. Very disappointing. I have blood cancer and my oncologist mentioned resveratrol as part of my upcoming treatment plan but he's on a two week vacation and I'm not patient enough to wait for him to sip martinis for two weeks. The bottle was about $35 for 30 days of 1,000mg doses, so it wasn't even that cheap.
I’m want to know where he gets HIS resveritrol or if he could recommend a brand
me too baby.....
how to choose the best resveratrol supplement ??
Trierlabs has a 2000mg resveratrol I take.
I use resveretrol with pterostilbene, and I take them with a little oil like avacado oil for absorption.
Do we need oil for absorption?
@@goodfins8167Yağ ile 5 kat daha fazla emiliyor suya göre
@@goodfins8167 yes
What name brand do you use
@Good Finns ...... Yes!
What about the Wilson study? Showed it increased artery plaque in rabbits! Could it do the same in humans???
WELL, HOPEFULLY WE CAN FAHUAK LIKE RABBITS AT LEAST!!🤷♂️
maintenance ?
Any feedback from anyone, 3 years since video was posted?
Is resveratrol from Sunfood a good choice?
Does resveratrol and/or NMN supplementation effect blood glucose levels in type-2 diabetics?
Nope-pathways are screwed from insulin resistance. you need to get rid of the visceral fat and hyperinsulinemia first although admittingly resveratrol will help. - Meat based KD sprinter
I'm still experimenting with the effects of resveratrol in my Pinot Noir, lol.
I'm taking mine with a teaspoon of olive oil!!
George Burns smoked cigars for years...Lived to his 90's
Does that mean you will start smoking?
Have at it, Rick! 😂
He lived to 100, so N=1 sample... nice study you have going genius.
@ Rick WW2 vet Richard Overton lived to be 112 and drank whiskey, smoked up to 12 cigars a day and ate can food and butter pecan ice cream.
@@scottpreston5074😅
So I can take it with ghee?
If you're adding it to yogurt in the AM, you're breaking your fast, right? Can you please explain since IF is a huge part of the protocol? I'm truly curious because I feel like I'm missing something. Thanks!
try mct oil
I am also trying to figure out the solution…since i do 24 hours fasting …and if i take it in the morning it would obviously break the fast.
Could any recommend a real good source of this supplement?
Eating grapes. Also check out Toniq Resveratrol on amazon.
Yes ,go to this website can buy a high quality one with hight tech which is suspension gel technology,95% absorption...www.jeunesseglobal.com
Sponsor name " blessyr"..the company will delivery to you whatever you stay, same price golbaly as membership! Login and register as a member pls!
Red Wine
Japanese knotweed.
Im genuinly on a diet of red wine with a fatty diet and have been for years im 32 now and i got a ultrasound of my heart and blood tests of kidney and liver function and everything was spot on and i had a perfect bloodcount how weird is that
Yes but you are 32 so no matter what you are on you would expect normal results.
I need some help. The reservation that I am eating is trans -reservatrol, but the capsules are like reddish beige/brown. Is it not good then? Does this mean that the reservation has to be white?
I believe so. The powder should be white and stored in a cool dark place
I believe it has gone bad. You need to find a reputable supplier, there are a lot of crooks out there. Some supplements dont even have the label ingredients in them.
Is trans-resveratrol the same thing?
we can supply plant extracts like resveratrol powder
looks similar if you eat a grape every day...Any study about difference of take this medicine and grape-eaters?
Anyone know of a good brand resveratrol to take?
Let me know if you get a reply! Thank you 🙏
Bulk Supplements might be good, but I don't know yet.
Vinia from Bioharvest
@@scottpreston5074 I take bulk supplements, amazing!
is this true that resveratrol having estrogenic effects on men ? I do not want to live longer without my mojo. some guys on reddit experiencing resveratrol as anti potent DHT even if they take 200mg per day , how the doc is coping up with 1mg per day
Well the doc doesnt seems to be the most masculine dude around.. BUT my guess is it depends on how good is your body in dumping the estrongenic hormones out of the body. Thre is a balance right. You need more male sex hormones and some female ones in your body to work properly. So if you get more female ones outside of the body, the body will reduce your own production. Just like with testoterone. Its your liver that get rid of the hormones via that galdbladder secretion. So if your liver is fucked up its not gonna be as effective in destroying the estrogenic hormones, and if your galdbladder is fucked - then you are gonna have problem literaly disposing of them. Plus - depends on your diet. You need fiber to get rid of the bile (and all that shit in it). And all the diets that are high in resveratrol (wine for lunch and dinner and maybe afternoon) - the greeks, the italians, and the french - its a very high carb, high fat, but also high in spices and salads and vegies and low on sugars. + the quality protein. So keeping your youth for longer is a complex task even if you are using some cheat codes like suplements.
This is wonderful but where can we buy high grade trans rev at ?
www.amazon.co.uk/Trans-Resveratrol-Japanese-Knotweed-Extract-bioavailability/dp/B07JZTFB54/ref=sr_1_4?dchild=1&keywords=resveratrol&qid=1595149326&s=drugstore&sr=1-4
This resveratrol is white/odourless.
ATP Labs is what I go with. The thing with supplements is the quality and regulation varies among each country. Canada is pretty strict with their process, and I have had very good results with their products.
atplab.com/products/trans-resveratrol-99?_pos=1&_sid=3bb354bfd&_ss=r
Trierlabs.com has a 2000 mg product that I’m very happy with.
@@Naturalremedies44440 but is not trans.
There have been several studies that have shown Resveratrol to cause cellular stress, especially during cell replication. I’ve taken it in the trans-res form for several years. After reading these studies I’m inclined to stop taking it. My biggest concern is that in more than one study, there was an increase in cholesterol.
Stress is more and more shown to increase health. Be it hypoxic, metabolic, heat/cold exposure etc.
@@joost1183 You're likely mis-applying the trope that resveratrol is effective in this case. It's likely that resveratrol doesn't provide the benefits as claimed by Sinclair. His results have failed to be replicated in multiple studies. It's likely that he maintains the fiction there is substance to the lie in order to ensure his payout by a company remains protected.
@@dudertino51 I am inclined to agree with you. Results from Sinclair are not repeatable apparently by anyone else. He blocks people from his tweeter acct when they post reasonable objections, that he could easily answer. I read his book, and liked what I read. But not all he says is solid.
So many years have passed and you are proven wrong. How does that feel?
@@user-pz7qv6ey4z no one has been “proven” wrong. This is the nature of nutritional science. We find positive effects, we try to trace the origins of those positive effects, then we attempt to replicate those effects, then we try to find the mechanism of those effects… We often get it wrong, or we often don’t understand the synergy that is occurring. So to use a blanket statement is not a way to conduct any type of conversation.
I am taking liposomal resveratrol. About 200 mg/day. But it is difficult to assess how this affects the bio-availability. There are so many questions. What kind of liposomes (research on liposomal CoQ10 revealed big differences in the various versions).
Trans-resveratrol has very bad bio-availability bit Sinclair says that if you take it disolved in Olive Oil the availability becomes 5-10 times higher.
Also: high disages of resveratrol could have adverse effects as it seems to be taxing on the liver (if I remember correctly). So I think resveratrol in a liposomal form could be a lot better, but who knows. It is more expensive.
I don't know if anyone can fill in here? Thx.
Resveratrol is beneficial for the liver in many ways, you’re misinformed.
@@shaygill5260did you ignore the part where he stated “high dosages”?
@@campersruincod6134 high dosages of anything will kill you even water, yes of course dose is important dose is everything we must tinker to find the right dose I agree but from what I've read in healthy doses it aids the liver
Solgar Resveratrol 500mg once a day is okay or not?
You've mentioned per gram that you are taking in powder form. Where did you get your source from? Are NMN available online like in Amazon are authentic NMN?
Pls advice.
Thank you Dr.Sinclair
I personally take 1g every day (since 5 July 2020) and so far i've had no side effects.
Unless you're 50 or older, there's no need to take NMN.
I’m taking 2000 mg a day.
@@madamex5541 after 30 , it is to think about
@@madamex5541 From where do you have the information about the age of 50?
500 mg diem still here doing very well. Make sure to exercise, it activates it. PLUS eat with fat a must. I keep mine in refrigerator trans micronised version with perion.
Vinia is the purest most absorbable resveratrol. Its cheap and amazing!
Sound quality... please improve it for this set.
I bougth transveratrol, I keep it in dark and fresh but inside the capsule it is brown.
Some people seem to say its dangerous so im confused.
Same here. The information is confusing and different everywhere you look.
Yo we need an update on da grape juice. I herd it wuz negative, am I rite?
I blend my resveratrol with organic cottage cheese and flaxseed oil, not sure if it helps.
WHY COTTAGE CHEESE 😭 But it doesn’t sound bad
@@hata6290 Google the Budwig Protocol
I noticed a very cost-effective, quality, and harm-free brand Vitruvin.
Hey, Anne! I am a Vitruvin user as well. I'm taking 500mg a day. So far it's been very effective. I've been complaining of fatigue before. But now I don't find it difficult to keep up with my day-to-day routines anymore.
I am a Vitruvin user as well, this keeps me going everyday... like seriously! My life has changed.
They say red wine isn’t a great enough source based on the quantity but what about the bioavailability of resveratrol from wine
Just read this article: Resveratrol: Twenty Years of Growth, Development and Controversy. I´m kind of confused... Anyone?
I'm concerned about Dr. Sinclair's kidneys now.
I wish these negative studies were addressed more often.
@@cuentadeyoutube5903 what should be wrong with his kidneys?
Article link for those interested. Really interesting perspective from one of the early researchers of resveratrol. www.ncbi.nlm.nih.gov/pmc/articles/PMC6319551
Please up date . Last research on resveratrol on human with Crisp genetic tecnology , show the opposite . No sirt acrivation and even some demage.!!!!
The damage is obviously from CRISPR. It is a known risk of CRISPR
I’d like to know the truth about Resveratrol: is it good for you or is it potentially dangerous? Why did I have a very obvious, repeatable result from taking resveratrol?… I never expected any visible results from taking it but I began to see that it was indeed responsible for increased endurance in a strenuous “ yoga with weights” class during which we increased heart rate and worked our muscles to their limit. I tested it over and over again. I stopped taking resveratrol because of the negativity around it, but I also had to stop taking the class!
The 1000 mg doses people like to do are megadoses and hepatotoxic since the liver intercepts and purges it so efficiently. 100 mg. liposomal resveratrol is the gold standard. - Meat based KD sprinter
I alternate, weekly, between alpha lipoic acid and resveratrol.
Interesting! Any logic and/or literature to support this cycling? Thanks.
Good stuff
And use can prolong life if someone is living with cancer for a long time.
Dosage please? And what type of fats do you use?
Olive oil or little (greek) yoghurt
I just bought resveratrol from Nutricost they look brown are they still good then I’m confused not I keep them in a dark cold place
a lot of this stuff is fake. Liposomal resveratrol from Renuebyscience would be the gold standard. - BCAA/Protein restricted keto sprinter
My Resveratrol is brown... I just assumed that was because of the ingredients. Japanese knotweed and grapeskin extract.. now I am wondering if it is rubbish???
It's rubbish. There are so many snake oil nostrums on the market that many should be banned.
@@scottpreston5074what color is it suppose to be? Powder and capsule thanks
Interesting that PeterAttia does not believe the Resveratrol results from David’s lab, hence the possible positive effects of it ... any feedback on that would be very interesting
I don't know what to believe. I read a bad metastudy in which the Autor was not Objektive but rather hateful. Not sure if it is the hate club David mentions or if the author was just really annoyed.
@@SoulRoh interesting
I take a gram, or maybe it's a half gram, I don't know, I'm a scientist. Wait, what?
Exactly!!
I just got my first - Trans-Resveratrol 1000 - by ProHealth. And it's light green in color but David says it should be white. I bought it from ProHealth only after thorough research, but I feel disappointed as it is not white. Shall I throw it because it is not white, but light green? It's not brown either. It was shipped to me to Dubai, could be due to the distance it had to travel to reach to me ? PLEASE HELP !!!!!!!!
Why don't you take a picture of it and contact prohealth?
Just got some trans-resveratrol 600mg (japanese knotweed) ... however, it's brown ... which is making me think if I should return it hmm. thinking supposed to be white?
I'm using a brown one to great affect.
Thought it was said the capsule should he white and the powder brown? If so you should be fine.
Rhonda I watched your 30min video breakdown of NMN, NR precursor to NAD+ , you mentioned the side effect of enhancing cancerous tumor growth, but myabe not a cause of cancer itself. I am seriously thinking about taking NMN, but this bit of info scares me a bit. How great of a risk is there?
NMN supplementation is pretty experimental at this point. There's a whole lot a person can do before even crossing that chasm... why not let the research proceed for a bit first? You also have the problem of actually sourcing real NMN in the first place.
@@FoundMyFitnessClips I saw its experimental status, but by all accounts it sounds like it makes sense to take, your vid was the only source so far that I saw that reported potential adverse.
It seems there are many sources to get an NMN supp online, but that's another situation. What are other sources before considering NMN?
Hi Robert, listen to David Sinclair on his podcast addressing this (33:39-40 mark specifically, but the entire podcast is good): czcams.com/video/bRWT7hVgwuM/video.html
Hope it helps
ربي يشفي كل مريض
Questions: if your Glycocalyx Structure is not working properly then you may have a big problem absorbing anything.
How to improve ?
Dr DS says not to take brown resveratrol but he doesn't say which colour it should be!! So, my question is: What colour should resveratrol have? 🤔
White
umm, i just bought some resveratrol and it was brown. i thought it was supposed to be white. should i be concerned?
i think i got my answer. well then the supplment I got was bull.
How about pterostilbene?
Great!
i noticed the most popular brand is NutriVein
Why would Glaxo ditch resveratrol research after spending much time researching resveratrol???
Nothing 'natural' works for them. They have to be able to patent something so that the patient must get a script. Especially with Post pandemic vaccine agendas. The nano tech is patented and the body that it occupies essentially will belong to the company. it's not about health but control.
Maybe because they couldn’t replicate it and make big bucks from a pharmacy made concoction. Studies of Redox molecules were also dumped because big pharma couldn’t replicate it.
I started taking resveratrol in response to the NIH recommendations that resveratrol is likely effective in treatment of COPD. I am taking high dose, always over 1000 mg per day. If anyone has information on specific sourcing of this supplement I would appreciate advice. Right now I am getting varied brands off Amazon and alternating them, since I am sure some are more effective than others.
Lipo resveratrol is the new gold standard. drop the standard non bioavailable garbage. - BCAA/protein restricted keto sprinter
What about Pterostilbene?
the problem is you cant take it everyday , i did experiment and used it one day was perfect and next day caused damage and oxidative stress weakness , you need to recover like 2-3 days before next dose
@meow purr because i tested it on myself ?
@meow purr of overdose ? Basically my genetic material got damaged heavly , huge stress and my organs went crazy during meal intake like they havent seen this in months , rememebr blade 2 scene when blade drop some blood on suckers body , thats how i digested my food at my "break " resveratrol fast
@meow purr damaged your genetic material heavily? Bro u sound idiotic. Please dont give out advice if your barely know what the fuck youre talking about
@@damiandamiano3651so your generic material has been damaged by grapes
funkyguy9 Grapes? Yes, if you ferment them and drink like mad.
What colour should it be? The ones are on sale are all brown. What is the best source please? Thanks for the video.
www.british-suppliments.net
Clean and very high quality.
Pure resveratrol is colorless. In powder form, it is white.
IncognitoTorpedo where do you find the good stuff?
@@Splassshhh1234
I have provided a link already for the best out there.
I have no affiliation with the company.
The link is bad
So in short don’t take resveratol when you’re young and competing athletically? Take it when you retire to reverse crllular aging?
which brand does he take ?????
He uses conventional NMN. but the gold standard since 2019 is Renuebyscience or Codeage's liposomal NMN. NR or NAD. - Meat based KD sprinter
So does resveratrol cause breast cancer??? Cuz my mom had breast cancer and I’m taking resveratrol for a long time already but still have confusions and concerns
I am confused too! I have had breast cancer 14 years ago and it was oestrogen ‘fed.’ So I do not want a reoccurrence and have just bought trans resveratrol. Now I am not sure if I should take it?? Wish someone would clear this question up - in simple words.
Gorgeous1x always I stopped taking it. It does act as estrogen so yeah. It’s not for us unfortunately
@@gorgeous1xalways122 try to take supplements of iodine. I read that iodine is poor in every body it will help with vitamin D
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The only one I can find and use is 60mg (twice a day so 120mg total) and David has been taking a lot more. Sometimes I feel like I am just wasting money on supplements because dosages are inappropriate (too low). Same thing with D3. Recent studies (can be found here on YT) suggest that you need something like 50K IU, and we are being sold something in the lines of up to 5K IU which has no effect or insignificant effect (not to mention that the cost is not negligible for people not living in the high income countries).
you do not need 50k iu of d3 every day. that's something your doctor will tell you to take if you're defficient.
5000 is good it’s all you need
2:39 Take it with fat, olive oil or yogurt fro instance.
Are they saying to much antioxidants may be bad?
Yes
I have started taking 1000mg NMN on an empty stomach and then afterwards 1000mg resveratrol either with food or yogurt....but I find that I am feeling really tired after taking the resveratrol, is this normal?
Resveratrol absolutely hates being on its own. it likes it when there's a sirtuin activator already present (exercise. fasting. NMN), It also has serious bioavailability problems on its own since the liver intercepts and purges it as a foreign agent. the 1000 mg doses you are using is a megadose.. in other words. hepatotoxic. Switch to liposomal resveratrol and dial back to 150 ng. -Meat based keto sprinter
I like to get it naturally in Ho Shou Wu.
That’s great stuff
Knot weed I think.
@@purpleduck3494 Yeah I heard of that too.
My dad is 68 and hes willing to take 1g a day. Ill update you all!
Any updates from him? I started taking 1g a day since 5 July 2020 (I'm 26 years old).
@@madamex5541 thinking about doing the same...
He forgot about us!
?
How many milligrams are in 1 g. The most I have found per serving us 2000 mg.
Twice a week I take liquid brown resvereteol and it works.
Its a very low dose
How much resveratrol and NMN to take?