Making Piperidine to piss off my FBI Agent

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  • čas přidán 3. 06. 2023
  • Making Piperidine via the hydrolysis of piperine from Black peppers
    My source: www.sciencemadness.org/talk/vi...
    Chemdelic ahh title numero tres
    Everything in this video is common knowledge and is meant to educate people about chemistry, even though i use satire , this experiment has many dangers dont attempt.
  • Věda a technologie

Komentáře • 164

  • @pxlseyy
    @pxlseyy Před rokem +437

    Now, turn piperidine into black pepper to get off the FBI watchlist

    • @markiangooley
      @markiangooley Před rokem +6

      Piperine is more complex than I’d thought! Probably more work than making many controlled substances.

    • @popbomb6528
      @popbomb6528 Před 10 měsíci

      Power play.

  • @konstimikirtychyants5862
    @konstimikirtychyants5862 Před rokem +221

    Your polish accent can be heared from space and its wonderful

    • @Sans-hf9cx
      @Sans-hf9cx Před rokem +2

      i'm polish but i didn't hear it

    • @bazooka93
      @bazooka93 Před rokem +9

      @@Sans-hf9cx oh no, it's very clear.

    • @nezu_cc
      @nezu_cc Před rokem +3

      idk if I would call it "wonderful". I'm Polish, and I have to actively focus on what he's saying to understand everything. I can watch most English videos at like 2x-3x speed but not this one.

    • @Jmvars
      @Jmvars Před rokem +2

      heard*

    • @mrdanger4851
      @mrdanger4851 Před rokem +4

      Polish are know to be extremely smart

  • @ForgottenModders
    @ForgottenModders Před rokem +189

    Please never stop this unhinged chem. We all love it ♥

  • @nylanx5737
    @nylanx5737 Před rokem +81

    Rusty ballisong = essential lab equipment

    • @GerinoMorn
      @GerinoMorn Před rokem +4

      you need to occupy the ADHD somehow while shit is filtering

  • @randomcat1015
    @randomcat1015 Před rokem +96

    discovered you yesterday! you are a perfect mix between nile red and explosions and fire

    • @DC_DC_DC_DC
      @DC_DC_DC_DC Před rokem +2

      YES!!

    • @cashlin86
      @cashlin86 Před rokem +2

      The spiciest of the 3.

    • @GerinoMorn
      @GerinoMorn Před rokem +2

      A big NurdRage influence, the clandestine vibe and all xD

    • @highbread817
      @highbread817 Před 11 měsíci +1

      It's like NileRed and Explosions and Fire
      After Dark

  • @rexaimo1
    @rexaimo1 Před rokem +61

    As your FBI agent i can confirm you are making me pissed

  • @nik.akhmetov
    @nik.akhmetov Před rokem +25

    the junkiest synthesis I've ever seen... love it!

  • @SlimThrull
    @SlimThrull Před rokem +6

    You know he's a legit scientist when he wears gloves to grind pepper.

  • @canonicaltom
    @canonicaltom Před rokem +5

    When you think you've made something super toxic, step one is tasting it.

  • @fbgmerk8178
    @fbgmerk8178 Před 11 měsíci +20

    Bro I literally love that you showed loperamide(immodium) as a opioid! It shows your knowledge :) not many know that! I just found your videos today, I love chemistry and pharmacology and this is all super interesting and your videos helped me read chemical formula’s better!

    • @Prussian_Blue
      @Prussian_Blue  Před 11 měsíci +4

      heh, the uses of piperidine were on wikipedia, and ive used loperamide to not use fentanyl, because it just sounds bad, thank you though!

    • @Suitswonderland
      @Suitswonderland Před 11 měsíci +1

      mu-opioid receptor agonist, we don't call all of them opioids because then it would be a mess with classification, amitryptaline would be an "Opioid" if this was the case, pharmacology and science in general is terrible with terms and names, also lol wikipedia, lol fentanyl bad, I knew this channel would be garbage when I looked at all these comments which came straight from reddit.

    • @rolux4853
      @rolux4853 Před 9 měsíci

      @@Suitswonderlandhe sad it sounds bad because of the current epidemic of dirty chinese powder that’s coming through Mexico into the USA.
      It has become a very bad stance in society, even if it’s the most important and safe(!) opioid in a medical setting.
      You absolutely need it in every hospital for every bigger surgery and you can safely does it for pain patients in patches.
      It’s one of the most prescribed opioids in Europe because of this in other countries that don’t have an opioid crysis because the threshold to overuse it is much bigger when it’s a patch that only releases a certain amount every hour.
      I don’t want to into the possibilities of how a person could easily extract it or use it not subdermal like prescribed, but in a different way, but that’s usually not how pain patients up their doses.
      It’s not as easy as popping one more pill than usual and it’s very short acting on it’s only and only the patch form makes it very convenient for a lot of people since they just have to slap it onto their leg and „forget“ about it and live their life.
      Unfortunately the American public is unbelievably dumb and so are the media companies and the politicians.
      They could easily pressure China to stop sending tons of that stuff over, but they love the sweet sweet money that China prints without any repercussions for their own ecosystem.
      They have closed markets and all the money they print to buy foreign companies is never coming back into their own economy, so no inflation, only more and more wealth and power all over the world.
      This is well known, but managers and politicians all over the world still suckle on their little wanna be red Schmeckels for their own personal gain.
      This world is doomed because of fucked up people in powerful positions like them.
      Who only care for money, bloody, dirty money from fascist governments that try to destroy what’s left of the dystopia we once called the free western world.
      The most insane thing is how dumb the masses have become that they believe all the insane Bullshit the politicians talk and how they ignore the real problems completely, while caring about the most minuscule dumb shit.
      But I guess that’s what you get if your public schools are so unbelievably bad, that it’s even allowed that they teach fake biology and history lessons.
      Manipulating children into thinking that the world is only 2000 years old is insane and should be considered a crime against humanity!
      Everyone can have their own religion, but they still ahead to accept sciences and have to understand that religion isn’t to be meant word by word.
      Hell that’s exactly what Jesus himself is saying over and over in the so called good book!
      Listen to the moral behind the story and not the story itself!
      It is batshit crazy to me that in the age of unlimited information for even the poorest of our western society we managed to become much dumber than in the ages when knowledge was an almost unachievable luxury!
      The whole worlds knowledge is literally at our fingertips!
      I bet this completely off topic rambling made you think „ok weird guy, who asked?“
      But sometimes I need to get on my soapbox, even if there’s usually nobody listening and people just rolling their eyes about my take.
      Yes, I know.
      I know.
      I guess I’m the crazy one then..
      I wish I could live like Moebius in a lovely insane asylum with likeminded highly intelligent and intellectual people like in the satiric drama „the Physicists“ by Friedrich Dürrenmatt.
      I just love the read the written book, but unfortunately could never see it on stage yet.

    • @user-in8bz3kd7d
      @user-in8bz3kd7d Před 4 měsíci

      ​@@Prussian_BlueTo be honest, your video is very interesting and inspired me a lot, but I don’t want to do this at the moment. What I want to do most is to extract ricin from castor beans.

    • @robertguenther6710
      @robertguenther6710 Před 2 měsíci

      People have been using loperamide for years to combat opioid withdrawal but its dangerous as fuck, you take to many and you can end up being a vegetable for the rest of your life among other diseases, the two shouldn't really even be used in conjunction but lots of people Hear there an opioid and think they work like one but they don't, better off using Kratom or very small dose of benzodiazapine

  • @tonyflamingo3285
    @tonyflamingo3285 Před rokem +47

    Could you not just make a birch reduction on pyridine? It would be cheaper I think.

  • @joho0
    @joho0 Před rokem +5

    I was just sitting here thinking about all the different psychoactive substances Sasha Shulgin was able to make starting with piperidine.

  • @shatterthemirror8563
    @shatterthemirror8563 Před rokem +5

    Sometimes the clandestine and the chemistry go hand in hand. Sometimes they go in handcuffs.
    Sometimes they just get out of hand.

  • @geekswithfeet9137
    @geekswithfeet9137 Před rokem +44

    When crashing out of a dual solvent mixture, do it drop wise under minimal stir. You will grow larger crystals.
    And if contaminated with a non-polar wax like this from isopropyl, gradually add a salt such as CaCl2 that's strong enough to break the miscibility and salt out the isopropyl into an organic layer. Carefully done, this does half the work up for you, and means not filtering gunky mess but nice clean powder.

    • @tomasmarz6713
      @tomasmarz6713 Před 7 měsíci

      Exactly! If this is done carefully, the piperine crystals are not contaminated with oil and other ballast substances. When using highly pure piperine, the subsequent piperidine is also purer. It is a good idea to subject the extracted piperine to several recrystallizations. After all, the whole preparation of piperidine is then easier.

  • @Antonio-qm3bi
    @Antonio-qm3bi Před rokem +3

    Bro you need a Büchner and a vacuum pump so bad... 😂

  • @chemistryofquestionablequa6252

    Funnily enough, I was talking about piperine to piperidine synthesis just yesterday. Totally not for nefarious purposes...

  • @joejoemyo
    @joejoemyo Před rokem +3

    Pepper: sold in stores
    Drain cleaner: sold in stores
    Pepper+drain cleaner: watchlist

  • @That_Chemist
    @That_Chemist Před rokem +3

    I mean, its not _that_ much like benzene, but hey it was a segue

  • @superturkeylegs
    @superturkeylegs Před 10 měsíci +1

    Nilered did a similar extraction. Word to the wise: a soxhlet extractor makes the process more efficient and uses less solvent.

  • @bradgirod3292
    @bradgirod3292 Před rokem +3

    I use a butterfly knife to support my chemistry apparatus too.

  • @skyethebi
    @skyethebi Před měsícem

    The best part is you can also use the piperic acid to make other illicit drugs

  • @frankroberts9320
    @frankroberts9320 Před rokem +6

    The molecule shown at 00:24 is pyridine, not piperidine.

  • @Hamza-B3
    @Hamza-B3 Před rokem +3

    The most blunder filled video ive seen to date😭cant wait for the next

  • @nunyabisnass1141
    @nunyabisnass1141 Před rokem +7

    Was, was that a chemistry grade butterfly knife?

  • @docE3885
    @docE3885 Před rokem +2

    Why do you not pull a vacuum to help with the filtering process?

  • @oleg3123
    @oleg3123 Před rokem

    i love these simple, short videos

  • @galleryofrogues
    @galleryofrogues Před 9 měsíci +2

    How to make fentanyl from black pepper 😂

  • @williambock1821
    @williambock1821 Před 11 měsíci +1

    The FBI is gonna be watching for the three Imodium AD pills you can make ,now.

  • @AlligatorKrokodil
    @AlligatorKrokodil Před rokem +7

    0:23 no piperidine is not like benzene with a nitrogen, that would be pyridine. you get piperidine by hydrogenation of pyridine and it is aliphatic and non aromatic, therefore has vastly different properties.

  • @reichsman9537
    @reichsman9537 Před rokem +9

    Man why do you hate your fbi agent?

  • @originalmianos
    @originalmianos Před rokem +1

    Get a Buchner funnel and a cheapass vacuum pump or a water Venturi pump. Super handy for any filtration.

  • @YeeModz
    @YeeModz Před rokem +1

    I want to see synthesis of mescaline , o-dsmt, amphetamines , amphetamines

  • @derLeomitmBenzer
    @derLeomitmBenzer Před rokem +1

    This is the eastern Europe Nile red we needed 😂

  • @thetaintpainter5443
    @thetaintpainter5443 Před 2 měsíci

    A benzene ring with a nitrogen would be pyridine. Piperidine is cyclohexane with a nitrogen

  • @robertguenther6710
    @robertguenther6710 Před 2 měsíci

    Please explain the relationship between piperine/black pepper and pyridine, there completely different compounds, I've looked it up but find nothing about piperine being used this way, what in piperine are you trying to isolate? What does it have in common with copper sulfate?

  • @artyombugrov3364
    @artyombugrov3364 Před 11 měsíci +1

    nile red’s evil cousin, prussian blue

  • @ananteshesha5788
    @ananteshesha5788 Před 10 měsíci

    Turning pepper into salt, nice

  • @personious_k
    @personious_k Před rokem +1

    Okay, i followed the steps exactly, but instead of ritalin, there's a squirrel water skiing in my pool. I think i messed up.

  • @TheUncleRuckus
    @TheUncleRuckus Před rokem +1

    @1:56 seeing a Balisong in such a sad state is absolutely heartbreaking!! 😭😭

    • @jamiehughes5573
      @jamiehughes5573 Před rokem

      Don't worry it's enchanted to inflict tetanus on use on targets

  • @CartiGIazer
    @CartiGIazer Před rokem +1

    Yo if u see this late comment just know I’m watching the live count rn waiting for the 10k post so I can suggest 2 things. Early congrats on 10k 🎉

  • @Amipotsophspond
    @Amipotsophspond Před rokem

    What if you repeated some of the extraction steps to increase purity.

  • @Plesio_
    @Plesio_ Před rokem

    when uranium extraction from ore or thorium dioxide from gas mantle?

  • @profpuffofficial2
    @profpuffofficial2 Před rokem

    Dont worry aboit a watch list,theres literally a gmp paper on how to make mdm@ from black pepper in kilogram on pubmed

  • @hotketchup100
    @hotketchup100 Před rokem +1

    I'm gonna be waiting for that pizza.

  • @jogandsp
    @jogandsp Před rokem +2

    It definitely is not like a benzene ring??? It's an aliphatic heterocycle, not aromatic.

  • @pawepiszczaka4490
    @pawepiszczaka4490 Před 6 měsíci

    I see Chemland enjoyer - i upvote.

  • @neffix6976
    @neffix6976 Před rokem +2

    So the benzaldehyde methylamine route didnt work? ;)

  • @MidMo4020
    @MidMo4020 Před rokem +1

    1:59 is that a butterfly knife under those rusty pliers? 🤣🤣 right tool for the right job 🤘🏻🔥

  • @roeberdt-bT.1021
    @roeberdt-bT.1021 Před rokem +1

    ...Thanks for the post, absolutely appreciated.
    (And hopefully you gave your fbi agent a good smile as well, you did make the dis-claimer and what else could you do.,...)

  • @yagvar
    @yagvar Před rokem

    this channel is so good

  • @koukouzee2923
    @koukouzee2923 Před rokem +3

    The chess blunder reference lol

  • @c.j.rockwell5803
    @c.j.rockwell5803 Před 11 měsíci

    You know you're in for some real shit when the chemist uses a rusty butterfly knife as an essential part of his distillation setup.

  • @amandahugankiss4110
    @amandahugankiss4110 Před rokem +3

    you may benefit from a vacuum filter setup
    love the anarchy :)

  • @emceeboogieboots1608
    @emceeboogieboots1608 Před 8 měsíci

    You have an FBI agent?
    Awesome!

  • @phobos1963
    @phobos1963 Před 2 měsíci

    Why didn’t you just hydrogenate pyridine ?

  • @jackass6257
    @jackass6257 Před rokem +1

    Ayyy I’ve been on Ritalin for my entire life basically, also buspirone, always been interested with pipers they are very versatile

  • @youregonnahaveaskeletontim1925

    ayo im subscribed, the pizza better reach me the next week.

  • @lookingforamxevendor2116
    @lookingforamxevendor2116 Před 3 měsíci

    How can piperine be converted into piperdone then 4-piperdone??

  • @jamiehughes5573
    @jamiehughes5573 Před rokem

    Jesse,we have to cook

  • @chanheosican6636
    @chanheosican6636 Před rokem

    Cool video. Dragondroff works as a test.

  • @TheHuntermj
    @TheHuntermj Před 8 měsíci

    Could you make Piperidine from 1-Pentylamine?

  • @Ori-lp2fm
    @Ori-lp2fm Před 5 měsíci

    This literally look like those caught meth pictures you get from your local Sudanese dealer

  • @justinblake420
    @justinblake420 Před rokem +1

    interesting you saved me some research steps
    i know what i want to make with peperidine

  • @chasemurfree3118
    @chasemurfree3118 Před 8 měsíci

    Catalytic Hydrogenation of pyridine using nickel will yield a greater amount of piperidine or using sodium and ethanol solution two in pyridine, tin, and HCl works as well, but what this guy doing is child's play he's a hack.

  • @spiderdude2099
    @spiderdude2099 Před rokem +1

    Slow filtrations make me want to uninstall life

  • @fifthycharaktersforaqualit7468

    Looks like a very basic chemical ingredient just because you can turn some chemical into a drug wich basically almost every chemical can be I wonder why its so "dangerous" I mean its not an extremely effective poision or explosive right?!

  • @thomasvanwyk
    @thomasvanwyk Před rokem

    Amazing job well done how are you well we not the only ones watching you

  • @Tjrissi96
    @Tjrissi96 Před rokem +1

    so is this like crack house brand Nile Red?
    I'm sold, subscribed.

  • @michaelharned8741
    @michaelharned8741 Před 3 měsíci

    Do not mix with carbon disulfide

  • @dronelabs556
    @dronelabs556 Před rokem +1

    I just lit of some cannon fuse attached to a ball of tape to piss of my Mafia fbi agent. Dumbass drove by real slow waiting for a boom. But it was just tape and cannon fuse. 😂

  • @ging35zid
    @ging35zid Před rokem +3

    Love this video ❤and thx for being European edit: oh wait your not

  • @900stx7
    @900stx7 Před rokem

    I will admit that all of this went right over my head, but how exactly does this piss off the FBI ?

    • @Prussian_Blue
      @Prussian_Blue  Před rokem +5

      pcp

    • @douglassmalls6934
      @douglassmalls6934 Před rokem +6

      @@Prussian_Blue I looked into it and even though it is far too efficient to matter you can synthesize MDMA from piperine. Its documented in a 2016 paper called "The synthesis and characterisation of MDMA derived from a catalytic oxidation of material isolated from black pepper reveals potential route specific impurities"

    • @johngotti332
      @johngotti332 Před 10 měsíci

      the main reason is because you can make fentanyl out of this

  • @pauljohnson3851
    @pauljohnson3851 Před rokem

    Phosgene next please!!!!!

  • @adrixyn
    @adrixyn Před 11 měsíci

    I dont understand how to make piperidine from piperidine hydrochloride, you just added water ? Wikipedia say that piperidine is a colorless liquid, why are your liquid yellow?

    • @Prussian_Blue
      @Prussian_Blue  Před 11 měsíci +1

      its yellow because of impurities, piperidine HCl is a salt of piperidine and hydrochloric acid. that's because HCl ions bond to the piperidine molecule when there is a bunch of HCl in the solution AKA its acidic if you increase concentration of OH ions, you make it more basic, the reverse of acidic. once its basic, the HCl ions leave the piperidine and piperidine gets "freebased", which means its now bonded to nothing. piperidine HCl is a powder and piperidine freebase is a liquid.

    • @adrixyn
      @adrixyn Před 11 měsíci

      @@Prussian_Blue thank you for the explanation !

  • @Hepad_
    @Hepad_ Před rokem

    Please make VX

  • @JeffreyCC
    @JeffreyCC Před rokem

    You have a FBI agent??!

  • @mrbaffo8359
    @mrbaffo8359 Před rokem +2

    when are you planning on making a rocket engine? This time btw you're gonna piss off the FAA and the NAR

  • @user-qf8sv2gb6o
    @user-qf8sv2gb6o Před 23 dny

    It's not on the DA watch list?

  • @monika.alt197
    @monika.alt197 Před 9 měsíci

    pyridine=piperidine now?

  • @DuckyFlips
    @DuckyFlips Před rokem

    that youtube money kicking in 💪

  • @djisydneyaustralia
    @djisydneyaustralia Před rokem

    Don't stop there , take it all the way to MDMA

  • @freexe392
    @freexe392 Před rokem

    Nice video

  • @thomasfranks8598
    @thomasfranks8598 Před rokem

    Can someone please remind me what piperidine is used for.

  • @lalolanda2239
    @lalolanda2239 Před rokem

    i dont understand when you say the words

  • @albatroz6966
    @albatroz6966 Před rokem +1

    Polski Czerwony Nil

  • @HouseBricksDoor187
    @HouseBricksDoor187 Před 9 měsíci

    Make piperazine next

  • @aga5897
    @aga5897 Před rokem

    How come you got your own FBI Agent ?
    Does that come with Amazon Prime or something ? xD

  • @DjEmo200
    @DjEmo200 Před rokem

    kozak total goat ziomek

  • @user-ir1fo4ne8e
    @user-ir1fo4ne8e Před rokem

    Something are met to be done by professionals at pharmacy Co not at home when have to make comment about Dea then that when not to do .some kid may try it and hurt himself or others

  • @unintentionallydramatic
    @unintentionallydramatic Před rokem +2

    Well RIP in peace ahead of time.

  • @monariza.
    @monariza. Před rokem +1

    Remember me when you get famous

  • @seungmoohan8152
    @seungmoohan8152 Před rokem

    yo benzene ring with a nitrogen in it is pyridine..!!

  • @pindamonhangaba72
    @pindamonhangaba72 Před rokem

    Tell us how to make tnt

  • @kazumasempai8002
    @kazumasempai8002 Před rokem +1

    Joder, que épico.

    • @minutemantercero1702
      @minutemantercero1702 Před rokem +2

      No esperaba toparme con un comentario español en este bidio. Aquí tienes tu like

  • @rotmistrgaal3784
    @rotmistrgaal3784 Před rokem

    Make Trinitrotoluene

  • @Zboubtoumou
    @Zboubtoumou Před rokem +1

    I wonder how your Channel survive.
    I have the impressions that CZcams do not care about Drugs related video
    Anyway, Very cool channel !

  • @Anon256-64
    @Anon256-64 Před rokem

    bruh nile red's cousin

  • @andrewmodell5889
    @andrewmodell5889 Před rokem

    Smoke a beer .....

  • @adambruh4339
    @adambruh4339 Před rokem

    Awsoem

  • @AbdullahMalik-yr2yr
    @AbdullahMalik-yr2yr Před rokem

    u r like the brother of nile red from whom u were separated in a crowded place. even ur name has a color name in it. but considering all the blunders, it makes sense that u r on the complete opposite side of visible light😁.