Organometallic Reagents and Reactions - Grignard, Gilman, Organolithium

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  • čas pƙidĂĄn 10. 07. 2024
  • Leah4sci.com/Metallic presents: Organometallic Reagents, formation and Reactions overview including the Grignard, Organolithium and Gilman Reagents
    đŸ“șWatch Next: Grignard Reagent, Reaction, Mechanism and Shortcut ‱ Grignard Reagent, Reac...
    Need help with Orgo? Download my free guide ’10 Secrets to Acing Organic Chemistry’ HERE: leah4sci.com/orgo-ebook/
    In this video, you’ll learn about the 3 most common organometallic reactions including how to create the individual reagents, similarities and differences, and how they react with different molecule types
    This includes the Grignard reagent, organolithium, and Gilman or organocuprate.
    You’ll learn how organometallics can be useful in organic synthesis questions for chain elongation, ring-opening reactions and more.
    You’ll also understand why the carbon in an organometallic reagent is so reactive, acting as the nucleophile in a reaction.
    â†Ș Links & Resources Mentioned In This Video ↩
    ▾Grignard/Organometallics Series Leah4sci.com/Metallic
    ▾Grignard Reagent Tutorial + Cheat Sheet Leah4sci.com/Grignard
    ▾Polar Covalent Bonding ‱ Ionic, Polar Covalent ...
    ▾Nucleophile and Base Analysis for Substitution-Elimination ‱ Nucleophile and Base A...
    ▾Oxidation and Reduction Series + Cheat Sheet Leah4sci.com/redox
    ▾Michael Addition Leah4sci.com/Enolate
    - - - - - - - - - - - - - - - - - - - - - - - -
    ⏱ In this video:
    [0:19] Defining Organometallic
    [1:48] Comparing Reactivity of Organometallics
    [2:53] Grignard Reagent - Organomagnesium
    [5:27] Grignard Reactions Overview
    [6:12] Organolithium Reagent
    [7:47] Gilman Reagent - Organocuprate
    - - - - - - - - - - - - - - - - - - - - - - - -
    Follow along with your semester by using my Orgo Syllabus Companion: leah4sci.com/syllabus
    For more in-depth review including practice problems and explanations, come join my online membership site, the Organic Chemistry Study Hall: leah4sci.com/join
    ❓Questions? Ask me here: Leah4sci.com/contact
    đŸ‘©â€đŸ« For private online tutoring visit my website: leah4sci.com/organic-chemistry
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Komentáƙe • 56

  • @xerib
    @xerib Pƙed 6 měsĂ­ci +1

    Leah, I really have to thank you for a deeper understanding in organic chemistry!!

    • @Leah4sci
      @Leah4sci  Pƙed 6 měsĂ­ci +1

      You're very welcome! Glad my videos are helping

  • @kozkirsehirli
    @kozkirsehirli Pƙed rokem +1

    I love u queeennn, u make this so easy đŸ€©đŸ€©

    • @Leah4sci
      @Leah4sci  Pƙed rokem

      Thank you so much! glad to help

  • @Souluble_87
    @Souluble_87 Pƙed 16 dny

    Thank u mam i was crying that i didnt understand this in coaching
    U simplified it a lot

    • @Leah4sci
      @Leah4sci  Pƙed 15 dny

      I'm sorry to hear this topic had you in tears, but I'm glad I was able to help clear things up for you!

  • @abirdas3955
    @abirdas3955 Pƙed rokem +6

    After a long time you are finally back, we would love to watch your organic chemistry videos regular basis..

    • @Leah4sci
      @Leah4sci  Pƙed rokem +1

      Thank you and you are most welcome to. With over 300 videos posted you should hopefully find plenty on any topic you're currently working on

    • @happysinghfrompatiala964
      @happysinghfrompatiala964 Pƙed rokem +1

      @@Leah4sci keep uploading mam

    • @JustLikeYouYT
      @JustLikeYouYT Pƙed rokem

      @@happysinghfrompatiala964 skm sir proud student

    • @irshadullahkhan6800
      @irshadullahkhan6800 Pƙed rokem

      ​@@Leah4scihi mam

  • @MsAbby.3
    @MsAbby.3 Pƙed 9 měsĂ­ci +3

    Thanks ms Leah ❀

    • @Leah4sci
      @Leah4sci  Pƙed 9 měsĂ­ci

      You are so welcome

  • @user-qk6nm1xp6c
    @user-qk6nm1xp6c Pƙed měsĂ­cem

    Hey, I love your videos. It has helped me out so much. Thank you.
    Can you make an in-depth video on gilmans reagent, it’s a little difficult to understand.

    • @Leah4sci
      @Leah4sci  Pƙed měsĂ­cem

      Glad my videos are helping and thanks for the suggestion. I don't know when but I will consider it at some point in the future

  • @BOLYANA
    @BOLYANA Pƙed měsĂ­cem

    Very clear..Thanks

    • @Leah4sci
      @Leah4sci  Pƙed měsĂ­cem

      You're very welcome!

  • @skandaswaroop
    @skandaswaroop Pƙed rokem

    Hello mam
    I am a student studying in high school in India
    I really loved your way of teaching organic chemistry
    There is no online tutor in India who can make organic chemistry this easy
    Thank you

  • @macho8555
    @macho8555 Pƙed rokem +1

    Thank youuuu 💐

  • @hashidulislam2911
    @hashidulislam2911 Pƙed rokem +2

    I dont have these topics in my syllabus but i understood n i love it moreâŁïžâŁïžđŸ„°đŸ„°đŸ„°đŸ„°đŸ„°

    • @Leah4sci
      @Leah4sci  Pƙed rokem +1

      Awesome that you're understanding it! This usually shows up in organic chemistry part 2

    • @hashidulislam2911
      @hashidulislam2911 Pƙed rokem +1

      Yeah its greatđŸ„°đŸ„°

  • @msvbalasubramanyam4601
    @msvbalasubramanyam4601 Pƙed rokem +1

    Hi mam your voice is very nice and your way of teaching is very nice ❀❀❀❀

    • @Leah4sci
      @Leah4sci  Pƙed rokem +1

      Thank you for the compliment!

  • @biswaditya938
    @biswaditya938 Pƙed rokem +1

    Thank you maam

  • @bakybabyx
    @bakybabyx Pƙed rokem

    Thanks for the awesome vid :)
    May I ask why the Gilman reagent [(CH3)2CuLi] wouldn't just attack the carbonyl carbon?
    Also do you have a vid on latent polarity and why it occurs?

    • @Leah4sci
      @Leah4sci  Pƙed rokem +1

      You are very welcome!
      Regarding why the carbonyl doesn't get attacked, this is considered a weaker attacker and follows a 1,4 addition mechanism. (Review Michael addition for this.)
      As for latent polarity, I'm sorry but I don't have a video on this.

    • @bakybabyx
      @bakybabyx Pƙed rokem

      @@Leah4sci Ah brilliant, thanks for the reply :)

  • @amberhealth9792
    @amberhealth9792 Pƙed 10 měsĂ­ci +1

    Awesome

  • @ChemSurvival
    @ChemSurvival Pƙed 9 měsĂ­ci +1

    After all of the MO theory and structural analysis is done (a tough task in itself), it is always about just two things: 1. where do the electrons want to go? 2. Can they get there? If not, see step one for the next easiest pathway and repeat!.

    • @Leah4sci
      @Leah4sci  Pƙed 9 měsĂ­ci +2

      I like it! So many Organic mechanisms can be simplified by just thinking about the electrons flowing from high density to low density situations. Thanks for watching.

  • @tientaicao4200
    @tientaicao4200 Pƙed rokem +1

    thanks,by the way can u tell me the product of this reaction?:C3H5RCOOH+H2O->?

    • @Leah4sci
      @Leah4sci  Pƙed rokem

      I'm sorry, but I don't offer tutoring over social media. For help with questions like this and more, I recommend joining the organic chemistry study hall. Details: leah4sci.com/joinï»ż or contact me through my website leah4sci.com/contact/

  • @anshdesai8238
    @anshdesai8238 Pƙed rokem +1

    Tommorow is my exam this video help me alot

    • @Leah4sci
      @Leah4sci  Pƙed rokem

      I'm so glad to hear that! I hope the exam went well.

  • @kakherbi
    @kakherbi Pƙed rokem +1

    Can you tell us how to make a video like this? Can you share what devices you use

    • @Leah4sci
      @Leah4sci  Pƙed rokem +1

      Let's keep the comments relevant to the video topic please.

  • @msvbalasubramanyam4601
    @msvbalasubramanyam4601 Pƙed rokem +1

    What are your best organic chemistry books reference ❀

    • @Leah4sci
      @Leah4sci  Pƙed rokem +1

      I prefer my own resources over any textbook! Find my entire free Orgo collection on my website at Leah4sci.com/syllabus.
      Or, for details on my membership site and resources, visit Leah4sci.com/join or contact me at Leah4sci.com/contact

  • @techofbengal3137
    @techofbengal3137 Pƙed rokem +1

    Reaction with acid chloride shoul be addition and elimination... Therefore first acetone will form..

    • @Leah4sci
      @Leah4sci  Pƙed rokem

      Are you implying there's a mistake in the video? If yes, thank you for bringing it to my attention. which reaction? (what time in the video?)

    • @techofbengal3137
      @techofbengal3137 Pƙed rokem

      @@Leah4sci reaction with acid halide ang grignard reagent... It should be addition via elimination... I mean grignard will react untill u use water... In first step u did not use water.. So first acetone will form... Then again grirnard nucleoplhilic addition occur..

    • @techofbengal3137
      @techofbengal3137 Pƙed rokem

      @@Leah4sci in the thumble given...

    • @techofbengal3137
      @techofbengal3137 Pƙed rokem

      @@Leah4sci otherwise u r wright... The answer will be decided by the given question....

    • @Leah4sci
      @Leah4sci  Pƙed rokem

      @@techofbengal3137 I still don't see an error in the video. Water was not added until after the second addition of the Grignard reagent to form the alcohol. An acid halide reacts with excess Grignard reagent to form a tertiary alcohol, NOT a ketone.

  • @rahulradhakrishnan2964
    @rahulradhakrishnan2964 Pƙed rokem

    Hi mam which software is using to create this animation video

    • @Leah4sci
      @Leah4sci  Pƙed rokem +1

      Let's keep the comments relevant to the video topic please. Thanks!

    • @rahulradhakrishnan2964
      @rahulradhakrishnan2964 Pƙed rokem +1

      @@Leah4sci not only you are creating the chemistry video in you tube. You thought all science and everything is in your mind, actually you got from alone.
      Anyway I got your software by the helps of artificial intelligence, I just paste your video link and asked to artificial intelligence, like below.
      Hi their, can you just tell me which software is used to create this video, here I am pasting the youtube video link.
      Lol Suddenly with in fractions of second the AI gave me the answer.
      😂

  • @arvindthakare5592
    @arvindthakare5592 Pƙed rokem +1

    I am really struggling in physical chemistry can you pls help me

    • @Leah4sci
      @Leah4sci  Pƙed rokem

      I'm sorry, but I don't offer tutoring over social media. Additionally, I am not a Physical Chemistry tutor. I help students with Organic Chemistry through my Organic Chemistry Study Hall.
      Details for that found at leah4sci.com/joinï»ż or contact me through my website leah4sci.com/contact/