Microtubules | Cells | MCAT | Khan Academy

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  • čas přidán 25. 07. 2024
  • Created by Efrat Bruck.
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Komentáře • 145

  • @guguwf1991
    @guguwf1991 Před 8 lety +174

    I learned more in 13 minutes of your video than in 2 weeks of class, thank you very much!

    • @thibauteloy6841
      @thibauteloy6841 Před 4 měsíci

      maybe because you were playing to candy crush instead of listenning the teacher ? ( I am joking)

  • @Santa1936
    @Santa1936 Před 7 lety +251

    Can be taken OOf. I love the accent

  • @carolinegreen4771
    @carolinegreen4771 Před 7 lety +113

    Microtubule is a much more complex molecule. The building block of this protein is a dimer called tubulin, which is composed of two sub units: α-tubulin and β-tubulin. α-tubulin and β- tubulin form a filamentous chain called “protofilament”. Microtubules are built by arranging 13 such protofilaments around an empty core. This gives rise to a tube-like construction (hence the name microtubule), which is stiffer, longer and wider than actin. Microtubules have a distinct organizing site called the “centrosome”. Microtubule polymerization begins at this organelle. The end where faster polymerization occurs is called the plus terminus. The end where slower polymerization takes place is called the minus end. Microtubules grow from the centrosome towards the membrane, by anchoring their minus end to the organelle. Once microtubules reach the membrane they detach from the centrosome and create a highly dynamic network. The formation of this network is assisted by a group of proteins with microtubule binding domains called Microtubule Associated Proteins (MAP).
    -Creative BioMart

    • @um1569
      @um1569 Před 7 lety +9

      That's exactly the kind of information I was looking for in this video, nonetheless it was a fantastic video, gave me more info than my professors did lol

    • @nilanjanadani5629
      @nilanjanadani5629 Před 5 lety +4

      Hey! May I know at what standard are you studying these Microtubules and stuffs? And from which country are you studying?😁

    • @hafsahjan4107
      @hafsahjan4107 Před 4 lety

      great...thankuu soo much...this helped me a lot.....stay blessed

    • @virupannamedikinal
      @virupannamedikinal Před rokem

      Thanks

  • @pragyasharma8238
    @pragyasharma8238 Před 2 lety +1

    understood all the basic concepts .. cleared my head with all the doubts by watching your video..thank u !!

  • @guyseavey6634
    @guyseavey6634 Před 8 lety +1

    Very well presented. It is very helpful when so many details are presented in a way that is easy to retain. Thank you for a great video lesson.

  • @AvParreira
    @AvParreira Před 8 lety +3

    A great presentation that takes a very dry textbook concept and makes is simple to understand and grasp.

  • @colife5486
    @colife5486 Před 7 lety

    wow- one of the best Khan Academy videos I've watched. thank you so much!

  • @betb48
    @betb48 Před 6 lety +2

    Wish i had a teacher like you at highschool...very well explained....

  • @leahgrausam5368
    @leahgrausam5368 Před 5 lety +1

    This is a phenomenal video! Well done! Thank you so much!1

  • @user-xp5or3fg9b
    @user-xp5or3fg9b Před 7 lety

    now i understand the paclitaxol and the other taxols mechanism of action thank you so much

  • @johnvandenberg8883
    @johnvandenberg8883 Před 7 lety +6

    Great work Efrat! New York accent? I love it how you say "beezlebaddies"

  • @ingaa.
    @ingaa. Před 8 lety

    Thank you so much, this video helped me a lot for a presentation!

  • @zannatul23
    @zannatul23 Před 7 lety

    thank you efrat, its really helpful x

  • @kevinbennett5226
    @kevinbennett5226 Před 9 lety +30

    You sound like you grew up in New York but now live in Canada

  • @tkal123
    @tkal123 Před 9 lety

    This is a very helpful video of an otherwise very confusing subject. Thanks

  • @FatimahWaleed
    @FatimahWaleed Před 9 lety

    It is very clear 💗 thank you so much.

  • @briansalkas349
    @briansalkas349 Před 6 lety +20

    Error at 3:13, centrosomes do not duplicate during mitosis, they duplicate during the S phase.

  • @doanviettrung
    @doanviettrung Před 9 lety +2

    This teacher makes everything so clear. Anyone knows her channel, please? I want to subscribe.

  • @kiranakhtar7788
    @kiranakhtar7788 Před 3 lety +1

    Time saving explanation... thank you so much

  • @manuelblank8072
    @manuelblank8072 Před 8 lety +24

    Correct me if I'm wrong, but aren't interpolar microtubules the ones that do not attache to kinetochores, but go from one MTOC directly to the other?

    • @MrFreakj
      @MrFreakj Před 4 lety +5

      Interpolar microtubules are connected to the interpolar microtubules of the other MTOC. Kinetochor microtubulues bind the kinetochors. So I learned it that way, too.

  • @ChildishDicaprio
    @ChildishDicaprio Před 3 lety +5

    All I got from this video was “OOOF” lol cool accent

  • @erikak6450
    @erikak6450 Před 2 lety

    I learned about microtubules AND Canadian accents today. Thank you!

  • @Skurkey
    @Skurkey Před 8 lety +4

    Very clear and well presented. Thank you for your time and talent.

  • @zannatul23
    @zannatul23 Před 7 lety

    thank you, you are a lifesaver

  • @russelmiller7311
    @russelmiller7311 Před 7 lety +1

    Both the mitotic spindle and the interphase cytoskeleton are formed from rapidly tuning-over microtubule populations with half lives of less than a few minutes, which grow from and shrink towards the microtubule organizing centres.

  • @johntindell9591
    @johntindell9591 Před 7 lety +2

    great work

  • @sowmiyasubramani1323
    @sowmiyasubramani1323 Před 4 lety

    Clear accent , and explaining ,, choose this kind of people to explain the session

  • @farihaakhter3946
    @farihaakhter3946 Před 2 lety

    This vedio is very helpful for all of us who want to know more about microtubules very descriptively or elaborately...

  • @merlinmystique
    @merlinmystique Před 4 lety

    you are great at teaching, thank you

  • @comfortkaimbo3
    @comfortkaimbo3 Před 7 lety

    this was a good job well done

  • @Tante90Emma
    @Tante90Emma Před 4 lety

    One of the best khanvideo I have ever seen.

  • @Twoplusfouris7
    @Twoplusfouris7 Před 9 lety

    Great job!

  • @redshark618
    @redshark618 Před 11 měsíci +1

    I dont know if her accent is NYC or NJ, but I love it

  • @ntethelelocilo3728
    @ntethelelocilo3728 Před 5 lety

    ngithande nje izwi lakho ntokazi yomngisi....i learnt a lot from this video, thanks!

  • @ahmadaamir7684
    @ahmadaamir7684 Před 8 lety

    Extremely helpful

  • @khamikos1
    @khamikos1 Před 7 lety

    perfect.thanks

  • @wardhammoud
    @wardhammoud Před 7 lety

    Much appreciated

  • @rawda2167
    @rawda2167 Před rokem

    Thanks it helps me a lot !!!!

  • @annikas2225
    @annikas2225 Před 7 lety +1

    This is so helpful for my AP Bio test!!! Thank you!!!

  • @misssweethearted
    @misssweethearted Před 9 lety

    this was actually pretty good

  • @TheSharkSoul
    @TheSharkSoul Před 9 lety

    I'm so grateful for this!

  • @himalaydebsourav
    @himalaydebsourav Před 3 lety

    An excellent class.

  • @ayaabdi9141
    @ayaabdi9141 Před 8 lety

    thank you..

  • @sudiptasahaniloy976
    @sudiptasahaniloy976 Před 9 lety

    thank u so much buddy..... :)

  • @guynouri
    @guynouri Před 3 lety

    Excellent clear clearest yet

  • @yiiyatschan1395
    @yiiyatschan1395 Před 3 lety

    Thank you for this video.

  • @TadFishy
    @TadFishy Před 7 lety +42

    There is a mistake in your video. Interpolar microtubules are antiparallel microtubules that originate from opposite poles, and overlap at the midzone of mitotic spindles. They don't attach to kinetochores. The ones you showed are kinetochore microtubules. Would be good to make it clear that there 3 types of microtubules taking part during mitosis and they all have different functions.

  • @krisanthonysilveira8244
    @krisanthonysilveira8244 Před 8 lety +2

    Just a small correction doesnt the microtubule arise from the pericentriolar material rather then then centriole ??

  • @pinkfrosting0
    @pinkfrosting0 Před 7 lety +20

    Love the jersey accent. Great video :)

  • @LeaBrigitteMagret
    @LeaBrigitteMagret Před rokem

    Thank you so much!

  • @virupannamedikinal
    @virupannamedikinal Před rokem +1

    Thank you so much.

  • @user-xu8pt6uy8h
    @user-xu8pt6uy8h Před 2 lety

    You are great.

  • @BrandonSLockey
    @BrandonSLockey Před 5 lety +1

    why are there no more detailed videos on this :(

  • @AvocaSingleTrack
    @AvocaSingleTrack Před 6 lety +10

    Brooklyn ? Queens ?? ...haha

  • @slehar
    @slehar Před 3 lety

    Wow!!!

  • @matthewlee4834
    @matthewlee4834 Před 7 lety +2

    I liked her accent, but it took a while for me to understand when she was saying "anchoring" at 4:09 xD

  • @jaquesfrancais3030
    @jaquesfrancais3030 Před 5 lety +1

    9:19 I think there is something incorrect, in the 9+2 arrangement of the basal body the central microtubules are NOT paired as the other ones (1 complete and 1 incomplete microtubule, who attach each other). Indeed, the central "pair" is more like TWO SEPERATE and both complete microtubules, just connected by a bridge and not direcly attaching, as your drawing suggests. Pls correct me if I'm wrong.

  • @rangineechoudhury3755
    @rangineechoudhury3755 Před 2 lety

    Well explained.

  • @ayoadeodebode4405
    @ayoadeodebode4405 Před rokem

    Great illustration. I must point out that the centromere and kinetochore lead the motion, not the arm of the chromatids as illustrated.

  • @mr.anti-islam7313
    @mr.anti-islam7313 Před 2 lety

    Thank you

  • @shikhakashyap5591
    @shikhakashyap5591 Před 4 lety

    I just loved this video😍😍😭😭

  • @nikiene5764
    @nikiene5764 Před 5 lety +1

    There is a mistake in your video. The 'interpolar' microtubules in the video are actually kinetochore microtubules. The interpolar microtubules extend from opposite poles and meet each other somewhere around the center where they overlap and associate with motor proteins.

  • @normadicn5700
    @normadicn5700 Před 4 lety

    Lovely accent. 🤩

  • @hamidizouina4787
    @hamidizouina4787 Před 7 lety

    plzzz what aplication do you use ???

  • @angelavolkov1126
    @angelavolkov1126 Před rokem

    Neat :)

  • @tanishagavali5171
    @tanishagavali5171 Před 4 lety

    This was so good.

  • @Greenthumb-420
    @Greenthumb-420 Před 7 lety

    does this come up on the grade 12 course or biology 30? im in process of needed to redo mine dont wanna waste my time learning it, if i dont need to

  • @Ngonyen401
    @Ngonyen401 Před 2 lety

    Thanks a lot..i pass the test because of your video 🤧🤧
    Got 15/16 🤗

  • @foadazizpur7442
    @foadazizpur7442 Před 8 lety +1

    URGENCY QUESTION: in the fungi, how chromosoms move in their nucleuses?
    does the strips of duke transformed from cytoplasm to nucleus?

  • @shizzassimplesciencesss5590

    Coool, I never liked khan's but this lady overwhelm me, keep it up miss unknown u r doing great

  • @angelavolkov1126
    @angelavolkov1126 Před rokem

    Can also grow by branching, not just linearly

  • @ThePassportPapi
    @ThePassportPapi Před 7 lety

    bring back khan!

  • @Shimulnath96
    @Shimulnath96 Před 4 lety

    Let me clear,, During synthesis phase(a phase of interphases) do the whole centrosome become double or only centriole become double?

  • @meeha7604
    @meeha7604 Před 9 lety

    How do u spell dionene correct way and what would happen of some consumes more then that is required by the body and where is it devised from plants or animal what is the structure of it compound element ?
    What would happen if tubular over grow do that me brain mass grows

  • @niloufarm.n6330
    @niloufarm.n6330 Před 4 lety

    What's this app u use for drawing?

  • @peculiarezindu1043
    @peculiarezindu1043 Před 5 lety

    Tnx for the teaching but signals did not go back they go forward from d dendrite to the axon terminal and then d axon terminal takes received signal to another neuron and so on continuously,,,,tnx again ma'am

  • @oraclebjj
    @oraclebjj Před 7 lety

    Reminded me of school again. Lots of labelling of parts less actual explaining of how stuff actually works. Are those tubules in the neuron as she calls them "tracks" transporting electrical signals? Or something else.

    • @lovelytangcalagan9264
      @lovelytangcalagan9264 Před 7 lety +1

      kimura kano No electrical signals aren't "transported" and the tracks that she showed are within the cell. The actual electrical signals that neurons transmit are passed in its plasma membrane through a complex process involving ion channels.

  • @Petrov3434
    @Petrov3434 Před 4 lety

    Kudos to Lynn Margulis

  • @user-xb7vt7pk7l
    @user-xb7vt7pk7l Před 3 lety

    That's a lot of protein names to remember

  • @tomasmieger6826
    @tomasmieger6826 Před 3 lety

    Amazing stuff - Thx.

  • @MikeyIV
    @MikeyIV Před 7 lety

    How do most cells transport vesicles? Just in the cytosol, no railroads? Also what holds the organelles of a cell (nucleus ER, etc) in place? Is that microtubules?

    • @yashikaraghuwanshi7634
      @yashikaraghuwanshi7634 Před 7 lety +1

      Intermediate filaments hold the cell together I think, and the railroads you talk about, are microfilaments.

  • @sajidaiqbal3688
    @sajidaiqbal3688 Před 6 lety +1

    isnt it kinetOchore

  • @chrisjernigan1912
    @chrisjernigan1912 Před 3 lety

    Shouldn't it be cawled the 9 +1 arrangement?

  • @user-sj8es7jh7r
    @user-sj8es7jh7r Před 2 měsíci

    very good video if u are student who got exam 2 days after

    • @enacausmembrane
      @enacausmembrane Před měsícem

      we actually say "2 days from now". The Word "After", makes it seem like you are studying after the exam has already ended.

  • @TheFr3styler
    @TheFr3styler Před 6 lety +1

    I thought Centrosome wasn't an organelle? 2:12

  • @rehanahamid4328
    @rehanahamid4328 Před 3 lety

    Centrosome is absent in plants....how spindle fibers are formed in them

  • @benashley2955
    @benashley2955 Před 7 lety

    if microtubules are dynamic then how is their structure studied

  • @swerasharma5218
    @swerasharma5218 Před rokem

    slay video

  • @williamaderera3371
    @williamaderera3371 Před 5 lety

    waht is kinetichore ,i didn't get it

  • @Andrew-kh7rz
    @Andrew-kh7rz Před 5 lety

    Is astonishing how much information is wrong on this internet

  • @Max-vi9is
    @Max-vi9is Před rokem +1

    Anyone here to understand orchestrated objective reduction?

  • @sushritbisht7863
    @sushritbisht7863 Před 5 lety

    This girl’s from Brooklyn!?

  • @madisonmarano2171
    @madisonmarano2171 Před 2 lety

    you must be from Jersey with that accent !!!

  • @ellastewart8122
    @ellastewart8122 Před 2 lety

    kind of vague.i still dint get the main functios of microtubules

  • @FishoeShoe_da_great
    @FishoeShoe_da_great Před 5 lety

    5:06 is this inside a cell or a nucleus?

  • @godhelpme8977
    @godhelpme8977 Před 3 lety

    Cilia and flagella 9 + 2
    Centriole 9 + 0

  • @guynouri
    @guynouri Před 3 lety

    Fast and furious

  • @notlarry6689
    @notlarry6689 Před 6 lety

    kinetochore is spelt wrong, she spelt it with an i rather than an o

  • @jamesfilosa6277
    @jamesfilosa6277 Před 8 lety +1

    Great!! Thank you!! One correction: kinetOchore* (it's spelt with O, not I) :S

  • @robertogalletti1182
    @robertogalletti1182 Před 3 lety

    Since when does Harley Quinn teach a microbiology class?