What is primary myelofibrosis? | Hematologic System Diseases | NCLEX-RN | Khan Academy

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  • čas přidán 10. 05. 2015
  • Learn what is primary myelofibrosis as well as how to identify its signs and symptoms, diagnose it, and treat it. By Raja Narayan. Visit us (www.khanacademy.org/science/he...) for health and medicine content or (www.khanacademy.org/test-prep/...) for MCAT related content. These videos do not provide medical advice and are for informational purposes only. The videos are not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of a qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read or seen in any Khan Academy video. Created by Raja Narayan.
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Komentáře • 30

  • @moevici7117
    @moevici7117 Před 7 lety +6

    one hell of an explanation thank you very much sir !!

  • @sinanaltinkok
    @sinanaltinkok Před 7 lety +2

    Great video .Thanks really much.

  • @nomnomnom3110
    @nomnomnom3110 Před 6 lety +1

    Excellent! Much thanks!!

  • @dolladolly3465
    @dolladolly3465 Před 9 lety +1

    so helpful .... thank you :)

  • @juscogens9068
    @juscogens9068 Před 5 lety

    Awesome video, world class!! Thx!

  • @barriebriggs1802
    @barriebriggs1802 Před 2 lety +1

    Brilliant presentation, thank you for explaining it so simply.

  • @vvvpuff2203
    @vvvpuff2203 Před 5 lety

    Wow it really helped me to understand this👏👏👏 thank you a lot.m

  • @KefirTView
    @KefirTView Před 6 lety

    Excellent explainer vid

  • @damian.gamlath
    @damian.gamlath Před 8 lety +2

    I love these videos, and you for making them!
    May I ask, what kind of hardware/software do you use to draw these diagrams electronically?

  • @tx7128
    @tx7128 Před 4 lety +1

    Thank you. Very nice presentation. Helped me understand what’s happening without having to listen to too much scary scientific names.

  • @sabeelalam7422
    @sabeelalam7422 Před rokem

    Appreciate your clear explanation.

  • @MichaelsUgly
    @MichaelsUgly Před 7 lety +5

    fibrosis due to platelet derived growth factor PDGF
    bone fibrosis -> extramedullaary hematopoesis -> hepatoplenomagaly
    spleen cant stop immature cell-blasts from leaving into blood -> leukoerythroblastic smear
    *bone has reticulin gates that prevent blasts from leaving until mature

  • @shrotriyayash2716
    @shrotriyayash2716 Před 5 lety +2

    Ruxolitinib Can Be also used as it is JAK-2 Inhibitor.

  • @bharathiraja3233
    @bharathiraja3233 Před 7 lety +2

    awesome video man... neat... thank u...
    I have one question. Why are there abnormally large platelets..?

  • @user-rk2fm3bn3u
    @user-rk2fm3bn3u Před 6 měsíci

  • @huddini-1343
    @huddini-1343 Před 3 lety

    quick question
    How does the marrow get replaced with connective tissue?
    Sorry if I missed anything.

  • @moomoopuppy5810
    @moomoopuppy5810 Před 6 lety

    So, is this body/skeleton-wide and all at once? I'm here because a fave of mine musician was just diagnosed with it. What is the outlook, as far as long term? Is it like dialysis, where the patient has to undergo treatments?

    • @pbonney
      @pbonney Před 5 lety

      Moo Moo Puppy I have it. It affects the amount of platelets my body produces. I take prednisone as a form of treatment.

    • @tx7128
      @tx7128 Před 4 lety +1

      Moo Moo Puppy I was diagnosed in 2001. It is chronic. Takes a while to get used to the medicine. I went to work even during adjustment to the meds. It is good to read about it. Join Cancer Support Group. Enjoy life. Take it easy.

  • @SidKzr
    @SidKzr Před 6 lety

    It this a situation of blood or bone cancer?

  • @laramariechan9840
    @laramariechan9840 Před 5 lety

    This is what happening to my aunt right now.. But we're still seeking for her medication.

  • @tx7128
    @tx7128 Před 4 lety +1

    May I ask why is myelofibrosis being discussed in Khan Academy? This is a rare form of chronic leukemia, usually diagnosed in people 50+. I was diagnosed in 2001.

    • @hannahbeanies8855
      @hannahbeanies8855 Před rokem

      This is for nursing /medical students.
      I’ve also been recently diagnosed with MPN as well. Im having a BMB to see if it is ET or MF

    • @laurelharris7244
      @laurelharris7244 Před 6 měsíci

      Because kids with interest in blood may be interested in microscopic variations…particularly if their parent has a MPN. I think this was a great source for my middle school duo trying to understand my complaints.