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wellnowdoctor
Registrace 26. 10. 2015
Caplyta
Caplyta occupies the dubious honor of being the 13th second generation antipsychotic granted FDA approval. Other members of the family include Zyprexa, Abilify, Risperdal and Rexulti. Unlike some of the others, Caplyta is only marketed to treat symptoms of schizophrenia. Caplyta is an oral drug administered once daily with meals. The dose is 42 mg.
Schizophrenia includes positive and negative symptoms. The positive symptoms of delusions and hallucinations may improve with Caplyta but the drug appears less likely to help the negative symptoms of apathy, social withdrawal and blunted affect.
Short term trials involving relatively few patients demonstrate relatively unremarkable improvement. Caplyta does not appear to offer any distinct or unique advantages compared to the other 2nd generation antipsychotics. For the cash price of nearly $1600 a month one would expect special benefits. The cash price of other popular generic antipsychotics may be as low as $10 a month.
Caplyta may interact with a variety of other medicines. A special black box warning cautions against use in elderly patients with dementia. Sedation and somnolence occur in up to 1 in 4 patients. Difficulty swallowing due to esophageal problems may lead to aspiration. Dystonia presents as spasm of the neck muscles, tightness of the throat and difficulty breathing.
Unusual movements of the mouth, lips, tongue and eyelids known as tardive dyskinesia may or may not resolve with discontinuation of therapy. Metabolic changes include increase in blood sugar, weight gain and elevation of serum lipids. The white blood count may decrease and potentially serious declines in blood pressure on standing also known as orthostatic hypotension expose the patient to potential falls and fractures. Seizures may occur.
Schizophrenia includes positive and negative symptoms. The positive symptoms of delusions and hallucinations may improve with Caplyta but the drug appears less likely to help the negative symptoms of apathy, social withdrawal and blunted affect.
Short term trials involving relatively few patients demonstrate relatively unremarkable improvement. Caplyta does not appear to offer any distinct or unique advantages compared to the other 2nd generation antipsychotics. For the cash price of nearly $1600 a month one would expect special benefits. The cash price of other popular generic antipsychotics may be as low as $10 a month.
Caplyta may interact with a variety of other medicines. A special black box warning cautions against use in elderly patients with dementia. Sedation and somnolence occur in up to 1 in 4 patients. Difficulty swallowing due to esophageal problems may lead to aspiration. Dystonia presents as spasm of the neck muscles, tightness of the throat and difficulty breathing.
Unusual movements of the mouth, lips, tongue and eyelids known as tardive dyskinesia may or may not resolve with discontinuation of therapy. Metabolic changes include increase in blood sugar, weight gain and elevation of serum lipids. The white blood count may decrease and potentially serious declines in blood pressure on standing also known as orthostatic hypotension expose the patient to potential falls and fractures. Seizures may occur.
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How about sciatica
Time for an update on the vaccines available now.
I wonder if rebound binges can occur when the body tolerates a dose of vyvanse or discontinues the medication. The fight or flight activation as a side effect of Vyvanse used to make me stress eat with sugary food items
My urologist didn't mention one single side effect to me. I'm not taking this drug now, Screw that. Thanks, Doc!
I took it with good results when I was younger, but now it causes extreme sweating.
20 year ago, I was told I would probably not be able to walk in 10 years without surgery that would leave me in considerable pain. I was nearing a point of daily opiate use. I was a drug abuse counselor, living out a story I'd heard about a thousand times. I knew where the road lead. For the past 10 years I have used kratom and physical therapy to remain upright, mobile, and off of opiates. Surgical techniques have improved considerably, so it is much less threatening, should I need it. I'm relatively healthy for my age. With the help of meds for blood pressure, and a low dose statin, statin, my blood work comes back within normal limits every 6 months. Not bad for 72 yo. Today's climate within the medical community toward opiates would have made it impossible for me to remain pain free. I would have been on street drugs without kratom.
I was prescribed 3x 200mg a day for two weeks now it’s been increased to 3x 400 mg I’m concerned this is too much! No side effects as yet AFIB gone and having ablation in 2 weeks! Should I continue with this strong dose until ablation!?
Is this guy trying to scare ppl off my taking meds
RIP. I loved you doc ❤
Yes there are very real dangers of this drug, however he NEVER mentions the benefits of it at all
Zostavax is dangerous. I got it in 2016, and have suffered Meneire's profound and chronic since 2019, Additionally eye problems and nerve symptoms. Another patient suicided. Zotavax needs to be banned worldwide, to prevent others from suffering what I have suffered. I am now on Valacyclovir which has suppressed Meneire's, but still have occasional episodes, and afraid may result in suicide.
I would love to hear him talk about magic mushrooms psychedelics. 😊
Which nsaids should someone with gastrointestinal ulcers take
Ruined my life...
Take it for sphincter off oddi dysfunct ion. It's been a blessing
Exercise? That’s what we’ve got? I cant frigging walk without pain.
Take your own fucking brain out and don’t screw with mine. Fucking quacks!
I’ve been taking kratom for 2 years now I was on gabapentin, wellbuteron and 3 other drugs that I have dropped for about a year now and no longer take anything but kratom daily. My chronic pain is also lower. So what’s safer the six drugs I was on or a plant. I feel it’s big pharma and their paid drs pushing this narrative.
Use Zyprexa and Depakene The problems I have are Weakness in perception and understanding Weakness in memory Aberration of mind Inability to talk to people normally Blurred feelings and sensations I feel like a restricted person With a loss of passion and nothing that interests me in all areas of life There is no sexual desire I suffer from bipolar disorder type 1 I am 29 years old
I got off that crap, now I have a cup of passion flower tea before bed, works like a charm, best sleep ever, with no side effects and no destroying my natural brain chemistry, and ling term dementia, are alytimers down the road, that no one talks about.
Dependence is not and has never been addiction. A diabetic is dependent on insulin not addicted. Severe chronic pain has always been successfully controlled by opiods. Fact.
The weight gain is crazy. Even on small doses you will gain a ton of weight
This must be a little bit old because last year over 100,000 people overdosed. mostly on Fentanyl.
Except for extreme pain, Why in the world would anyone ever want to be even close to a drug like Fentanyl. It just looks like an overdose waiting to happen.
I was on 10mg of Zoloft my whole pregnancy my doctor said it was safe 😢 my daughter was born early and had lots of problems and couldn’t eat on her own or breathe on her own she had excessive fluid in her brain and no bone in her skull her head was the size of a four year old at birth 😢 I named her Saphyra she died at 10 days old 😢 I’m still heartbroken
IF ANYONE IS GOING TO TELL YOU, IT'S THIS MAN.
Good heavens, look elsewhere for reliable information regarding dependency within very short period of time. Withdrawal after dependency, possible protracted withdrawal. Potential for serious heath consequences…
Worck good for lot of people.Not for me sadly ...im gonna try aubelity less bupropion 75mgr and cough supresor dextrometo ...? Adhd and mdd.sexualy assaulted with 7 -8 years .Disociative a lot.only methilfenidate help me jump from bed and be funcktional at worck but cant take a lot happened in my life .Excuse me im not anglo parlant 😅
I know this guy 😉, 30 yrs on opioids. Many, many attempts (all but once by medicated methods) to quit. Lots of 7 to 90 day duration failures. An ER Doc had a non-sensical, pig latin conversation with the opposite side of the privacy curtain before handing him a clonodine Rx for elevated BP due to withdrawls & sending him home. Stiff Clonodine/Kratom 5 & 10 days respectively, tapering both from day 1. Absolute cakewalk. Not even loss of sleep. He relapsed to the Kratom about 30 days later, but there was no real point/reward. He did take small doses of Kratom occasionally for another 6mos for diminishing depressive spells. That was over three years ago.
Know more about this subject than any person should. Been there, broke that, done that, through that, etc... This man is giving straightforward truth.
Don't understand why you're out of focus, yet the books behind you are clear & detailed?
Starting it tomorrow 🤞🏻
basically we shouldnt take any pill is what doctor is saying
I thought he said prednisone is a courtesan..
Repent and believe the gospel. Jesus Christ is the way! Believe in Jesus Christ. Not fortune!
I just got prescribed this and Amytriptilin, just looked up the dangers. NOT GOOD! 😢
It worked great for my pain, helped me sleep, until my doctor added DuLoxetine to it. Then winging off both the right way, I ended up in the hospital, thought I was having a stroke.
It may for on 60 percent of people, but the other 40 percent its a night mare. It destroyed my health.😢 Was on it and Amytriptilin, when winging off, it almost killed me, ended up in hospital. 😢 Any meds that mess with your brain, is not good to take, it also causes dimensia and alytymers, and mask your pain only, its not a cure for anything.
I was putting effexor everywhere in my nose on cat food etc... Now me and my cat are sober been 15 years of fun. 225 mg a day keep the doc away.
So is it better to take food/drinks after Rybelsus excatly after 30 minutes? Or better take them after more than 30 minutes?
RIP Doctor Landow. I just started watching your videos. Truly amazing Doctor. I’m always in search of great medical videos and Doctor Landow is outstanding. A genius. Thank you for sharing all your honesty and incredible knowledge. So helpful. God Bless. My condolences to family and friends.
I take hydroxyzine pamoate as needed for anxiety, it helps me a little bit but not as much like my Xanax.
I think it should absolutely be legal. However, i was taking a fairly large amount every single day for several years (being irresponsible.. not even using it to get off of aby substance) and was completely addicted to it. I recently started withdrawing and it has been quite difficult.
Dr. Could you please make a review on tizanidine please? It was prescribed due to spacicity as a result of a back injury...I'm bipolar and also have been diagnosed with GAD. Thank you. Best regards Dr!
They put me on entresto big dose 97 103 and i had echocardiogram of 59 ejection fraction ...i have angina
Feeling nice,better thencoffee
*Chucks packet in bin*
This drug disabled me with a ton of mental illness. This drug is no joke with adverse reaction.
Willow creek in Greenbay had me on seroquel morning and night and almost everyone else and they treated us like dogs and criminals
I about to suzieq my ass thanks doc