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clevaforce
Registrace 20. 11. 2021
4 NGS Workflow
This video reviews the steps involved in sequencing a sample using the next generation sequencing methods; from sample DNA isolation, through library preparation, sequencing and data analysis.
zhlédnutí: 242
Video
3 Emergence of NGS
zhlédnutí 53Před rokem
This video describes the evolution of sequencing methods from first generation single base sequencing methods, to next generation sequencing methods, also called high throughput sequencing and lastly the more recent sequencing methods called single molecule sequencing or what some describe as third generation sequencing. The distinctions between generations are discussed.
2 Overview of Sequencing
zhlédnutí 62Před rokem
This course provides an overview of the gene sequencing, differentiates the two sequencing generations, that is sanger sequencing and the next generation sequencing methods.
1 NGS Course Summary
zhlédnutí 45Před rokem
This course provides an overview of the next generation sequencing course contents.
Northern Blotting
zhlédnutí 4,7KPřed rokem
Northern blotting is a molecular and genetics technique used for the detection and quantification of specific RNA levels using a hybridization RNA probe. #healthscience #lifescience #blotting #genetics #RNA
Applications of Northern Blotting
zhlédnutí 1,1KPřed rokem
Northern blotting, as a technique for gene identification, helps to clarify gene functions. It has remained a standard method because it allows for the comparison of message abundance on a single membrane and can be used in determining transcript size. It can provide information about deregulated gene expression in malignancies such as cancer. #healthscience #lifescience #blotting
Applications of Southern Blotting
zhlédnutí 505Před rokem
One major application of Southern blotting is in the identification and cloning of a specified gene. #healthscience #lifescience #blotting
Southern Blotting
zhlédnutí 374Před rokem
Southern blotting is a technique used for the detection and quantification of specific DNA levels using a hybridization DNA probe. #healthscience #lifescience #blotting
Western Blotting
zhlédnutí 253Před rokem
Western blotting is a technique used for the detection and quantification of protein levels using a complementary antibody. #healthscience #lifescience #blotting
Applications of Western Blotting
zhlédnutí 289Před rokem
Western blotting is very useful in detecting and characterizing target proteins, allowing the detection of a single target out of thousands of proteins as well as obtaining molecular weight information about the target protein in the same experiment.
Introduction to Blotting
zhlédnutí 448Před rokem
Blotting is a molecular and genetics technique that involves the transfer of proteins or nucleic acids to microporous membranes. It provides a means of identifying specific molecules out of a mixture. These molecules can either be DNA molecules, RNA molecules or Protein molecules. #healthscience #lifescience #molecularbiology #molecular_biology #molecular #genetics
Northern Blotting vs Southern Blotting vs Western Blotting
zhlédnutí 1,9KPřed rokem
Summary of blotting types
Applications and Limitations of Targeted Protein Degraders
zhlédnutí 334Před 2 lety
Targeted protein degraders are useful in both drug discovery and cancer therapy with the potential to help treat 'undruggable' targets. There are however some limitations including cell permeability and bioavailability issues. #healthscience #lifescience #proteindegraders #newdrugmodality #drugdiscovery
The Ubiquitin-Proteasome System (UPS)
zhlédnutí 2,9KPřed 2 lety
The ubiquitin proteasome system (UPS) is entirely a protein degradation system. It is the cell’s primary pathway for controlling regulated protein turnover and consists of a series of enzymes which conjugate ubiquitin chains to a target protein in an event known as polyubiquitylation. #healthscience #lifescience #proteindegrader
Molecular Glues
zhlédnutí 1,3KPřed 2 lety
Molecular glue exhibit a unique mode of action by altering the surface properties of their target, either that of E3 or the protein of interest, which results in the induction of novel protein-protein interaction and the formation of ternary complexes between the E3 ligase, the molecular glue and the protein (of interest). #healthscience #lifescience #proteindegraders #newdrugmodality
PROTACs (Proteolysis Targeting Chimera)
zhlédnutí 3,6KPřed 2 lety
PROTACs (Proteolysis Targeting Chimera)
Applications of Alkyl polyglycosides (APGs)
zhlédnutí 321Před 2 lety
Applications of Alkyl polyglycosides (APGs)
Pysico-chemical characteristics of Alkyl polyglycosides (APGs)
zhlédnutí 145Před 2 lety
Pysico-chemical characteristics of Alkyl polyglycosides (APGs)
Synthesis of Alkyl polyglycosides (APG)
zhlédnutí 422Před 2 lety
Synthesis of Alkyl polyglycosides (APG)
Great video!
👍👍👍👍👍
Спасибо, невероятно интересно, вы очень хорошо объяснили это
Hello my friend, may I ask if your company needs anti-cancer drugs- (Including formula, raw materials, semi-finished products)? I am from China.
Cool thanks
Great field of work.
Best video
This video is not the right one, PLS change.
Very informative
Hello, Based in these definitions should it be seen that having a Type C meeting is more risky than a Type B meeting for a product approval for EUA? Risky in the sense that it might get rejected? And if things go right in that type C meeting is there subsequently a Type B meeting required for approval?
Best explanation ever 🔥
Faadiil
nice video on pharmaceutical formulation development lifecycle and product development
thank you for this video
Very informative. Better voice over too. Looking forward to the next video
Glad you like it, definitely more to come!
Good video keep them coming. This channel needs Promo'SM.