Neural Conduction, Action Potential, and Synaptic Transmission

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  • čas přidán 27. 08. 2019
  • We have probably heard that neurons are the cells that transmit information around the body. But how does this work? Is it actual electricity? Like from the wall socket? What is a synapse? What happens there, in between one neuron and the next? This is a really big and really important topic, so let's dive in.
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Komentáře • 157

  • @lijack3425
    @lijack3425 Před 4 lety +260

    More understandable and efficient than reading 20 pages of my textbook :)

    • @sreemohansharma5954
      @sreemohansharma5954 Před 3 lety +2

      Sadly term exams gonna ask qn frm txtbook

    • @anaghasunilkumar4906
      @anaghasunilkumar4906 Před 3 lety

      Plese share the notes on neurotransmission

    • @TheNutCollector
      @TheNutCollector Před 2 lety +2

      @@sreemohansharma5954 You're right about that. I wish we were tested on understanding, not what we can regurgitate from a textbook.

    • @spidey285
      @spidey285 Před rokem

      That's what it's all about!

    • @spidey285
      @spidey285 Před rokem

      @Sreemohan Sharma well at least now you can go through the material twice as fast (at least) and it'll be much easier to remember the key points and maybe even details! Just as long as you don't make excuses of course 😉

  • @ReiverBlue1971
    @ReiverBlue1971 Před 2 lety +12

    I love the fact that your vids are a good length at just under 20 minutes (so can keep your attention and focus) but feel like they're about 2 minutes long! Awesome stuff ;D

  • @toekneesee
    @toekneesee Před 4 lety +77

    This is such a great video; explains everything so well, and leaves no leaps of faith! Love how you included how "chemistry happens in picoseconds". Thanks Dave!

    • @maimahdi7373
      @maimahdi7373 Před 3 lety +2

      Yeah, I loved that too, cuz I was wondering about it, like there’s so much going on in our neurons and signals travel all these distances like. I AM WOWED

  • @joanneyazigi8977
    @joanneyazigi8977 Před 4 lety +3

    Thanks Dave! Honestly this saved me. I have a practical on Monday and we are required to know pretty much everything you explained on action potential. This is great. THANK YOU!

  • @bradsillasen1972
    @bradsillasen1972 Před 3 lety +1

    I've been watching and reading a lot about this topic but nothing compares to your presentations. The sophisticated graphics alone must take countless hours to create, let alone all the research you must be doing for all your material. Pretty mind-boggling in and of itself! Thanks for the hard work. I'll be signing up and donating on Patreon in the near future.

  • @bronwyngroves9781
    @bronwyngroves9781 Před 3 lety +2

    You are a life saver for a first year speech pathology and audiology student! these videos and the sound wave explanations have saved me!! thank you!!!

  • @Demothones
    @Demothones Před 4 lety +3

    I literally just started learning this stuff this week. Great timing.

  • @soulboken4670
    @soulboken4670 Před 2 lety +2

    Got a physiology exam in 2 days . 0 study done , watching a few vids of this guy can put me in a position where I can pass , shoutout to Professor Dave!!

  • @jillli245
    @jillli245 Před 3 lety +1

    Thank you so so much sir. I wish my professor could explain as clear as you did here. I've watched a lot of your videos before and they all helped me a lot.

  • @studymateanushka8679
    @studymateanushka8679 Před rokem +2

    My biopsychology teacher took 1 week to clear this topic and you finished it in 20 minutes amazing 🤩😍

  • @monalizacastillo7023
    @monalizacastillo7023 Před 3 lety +2

    This covers all of my questions. Perfect! I didn’t have to sit in class for hours.

  • @blerine3
    @blerine3 Před 3 lety +5

    I want to add another comment, THIS IS SUCH A GREAT VIDEO!!! I understand the concepts different receptors but most times, I cannot picture the connection and how it happens (how it jumps from one type of receptor to the next). THANK YOU SO MUCH

  • @Arjun-ho8tl
    @Arjun-ho8tl Před 3 lety +1

    Thank you sir,I was searching this topic for 12 hrs and I could not arrive at the right place ,untill I clicked this video.your work is Very understandable and useful.Really helped me!🔥🙏

  • @user-te6se3jj8k
    @user-te6se3jj8k Před 5 měsíci

    This is the most helpful videoseries i've come across for understanding biopsychology. Thanks a lot!

  • @raihanahnabillafirstyrahma7986

    Thank you so much! This genuinely saved my life. Wishing all the good things to come in your way!

  • @fehdivina4282
    @fehdivina4282 Před 7 měsíci

    Very explicit and simple to understand. Thank you professor Dave.

  • @luizatosi8323
    @luizatosi8323 Před rokem

    Best explanation I've seen so far. Thank you 🙌

  • @dianaprincessansah2524
    @dianaprincessansah2524 Před 6 měsíci

    great piece of work, very detailed explanation and easier to understand, thanks alot Dr.

  • @Luu_033
    @Luu_033 Před rokem +4

    Am having an exam tomorrow and this video just saved me....Thanks professor Dave❤

  • @charmmorningstar7530
    @charmmorningstar7530 Před rokem

    omg of all videos, this is the most informative and easy to understand. i have weekly A&P Exam and this is our topic. Thank you so much!!!❤❤❤

  • @anukamboj9715
    @anukamboj9715 Před rokem

    This is incredible. Makes it so easy to understand everything. You are magical.

  • @nooksirimar682
    @nooksirimar682 Před 4 lety +1

    Life saver !!! The explainations are so clear. Thanks so much for making this fab video

  • @blerine3
    @blerine3 Před 3 lety +5

    Professor Dave!! Thanks so much!! your videos and explanations answer even the questions i can't articulate. And, you have great and memorable analogies which makes it a lot easier to understand and to keep up!!!

  • @rishasarkar4657
    @rishasarkar4657 Před 3 lety +2

    Thank you so much, Professor Dave.

  • @studentslife2495
    @studentslife2495 Před 3 lety

    Amazing collection amazing work your reall teacher proud to be on CZcams 😊❤

  • @heltiswelt
    @heltiswelt Před rokem

    Incredibly helpful, thank you proff.

  • @ahmedehab8766
    @ahmedehab8766 Před 4 lety +1

    Thanks a lot, Dr. Dave. You are a great science HERO.

  • @sritharshanavet5310
    @sritharshanavet5310 Před 3 lety

    This part confused🤯 me a long time....This is the great video I've ever seen...This helped me to overcome my stress over this...again such a great epic❤️love it❣️Thank you🤝Mr.Dave for such a great video and explanation 🤩 really love it🥰

  • @humanhiveanomaly
    @humanhiveanomaly Před 4 lety +2

    Came here from professor Dave's post. Good vid and more so interesting to an EE. "Oh electrochemistry, what will you come up with next..."

  • @dhandapanibalasubramanian1813

    Nice understandable explanations. Thanks

  • @user-gj3gn4ph8h
    @user-gj3gn4ph8h Před 4 měsíci

    superb illustration

  • @aclearlight
    @aclearlight Před 3 lety +3

    Great content! It might be worth updating at some point to reflect emerging sense that cimpressional/acoustic waves in lbl and cytoskeleton are also playing a role.

  • @shambhaviupadhyay7719
    @shambhaviupadhyay7719 Před 2 lety

    Thankyou so much for making it easy and understandable 🙂

  • @roanhatleycouper7984
    @roanhatleycouper7984 Před 3 lety

    These videos are amazing thank youuuu, helping me pass my exams!

  • @NostressAdi
    @NostressAdi Před 3 lety +2

    Thank you! This finally makes sense.

  • @mariammaher6991
    @mariammaher6991 Před 4 lety +2

    Thank you , you’re a blessing 💚

  • @Somuntioalt
    @Somuntioalt Před 2 lety

    This is great! I was reading an article about electrophysiology, and I needed a quick refreshment of the matter. This helped a bunch! Super well explained!

  • @momnatabassam-0244
    @momnatabassam-0244 Před 2 měsíci

    It was really helpful. For the first time neuro was easy for me to study.

  • @ranahisham5850
    @ranahisham5850 Před 2 lety

    Thankyouuuuu u ve been so helpful for me since highschool ❤️❤️❤️❤️❤️

  • @AnzzCheatedOnMarkWithHaechan

    Finally undetood how action potential happen
    Thank you so much ❤️

  • @deborahr9188
    @deborahr9188 Před 3 lety +3

    Prof. Dave, I want to thank you for your excellent work and the quality of your videos, which has helped many students who are currently in remote education. However, I believe that it is not offensive that I point out a flaw in the content: the sodium-potassium pump does not only turn on at the end of the action potential, but has intermittent activity and is more active in repolarization, as sodium is stimulating for its functioning ; refractory periods also do not occur after the end of repolarization, but at the moment that repolarization begins, since the absolute refractory is caused by the return of the sodium channels to the resting shape, and the relative refractory is due to the membrane's hypernegativity , and therefore would need an additional voltage to cause premature potential and action. Despite this small point.. it"s a very great job!!

  • @mansirajyaguru9478
    @mansirajyaguru9478 Před 2 lety

    Thank you so much for making this video..... I even watched your muscular contraction video it made all my doubts clear...Great video

  • @mesibra2976
    @mesibra2976 Před 4 lety +6

    I really like your videos even though I can’t understand everything bcz I’m not a native English speaker which makes it hard for me to get everything clearly .. but your videos still so helpful . I appreciate your efforts , thank you so much .

  • @gaoxoxo
    @gaoxoxo Před 3 lety +14

    I am reading this in my biopsychology textbook right now, and I didn’t understand ANY of it until I watched this video.

  • @johnmiguelsadiasa7510
    @johnmiguelsadiasa7510 Před 2 lety

    thank you professor Dave!

  • @myatthuswe6093
    @myatthuswe6093 Před 3 lety

    amazing explanation thank you

  • @rileyrich4090
    @rileyrich4090 Před 3 lety

    Great explanation, I almost can relate to everything you said, lol so much information. Good thing that’s what our brain is for. To hold information.
    Great job from the U.S.

  • @MaNnAt_DHimAn
    @MaNnAt_DHimAn Před 2 lety

    nicely explained thanks

  • @santicruz4012
    @santicruz4012 Před 3 lety +1

    I was drinking water when 7:46 suddenly appeared lol
    Another great video just when I needed it the most, thanks proffesor!

  • @ashcam1791
    @ashcam1791 Před 8 měsíci

    Your videos are study miracles! Thank you Thank you Thank you!!!!!!!!!!!!!

  • @toothextractionmadeeasy214
    @toothextractionmadeeasy214 Před 2 lety +12

    It happens in milliseconds millions of times in every activity we do. And he took 15 minutes to explain its summary. Only one word.
    Great teacher ❤️
    And subhan Allah

    • @AyseY
      @AyseY Před rokem

      great teacher is 2 words but i agree 😭😭😭

  • @mrkps1986
    @mrkps1986 Před 2 lety

    just love your work

  • @The_Broken_Smile
    @The_Broken_Smile Před rokem

    I'm really thankful.

  • @Hasty_Bahadin
    @Hasty_Bahadin Před 3 lety

    Thank you professor dave

  • @juinishat7736
    @juinishat7736 Před 3 lety

    Thank u sir,this is really helpful.

  • @qball2929
    @qball2929 Před 3 lety

    Liked this video after the intro played. Top notch intro. 7/7

  • @mitkumamo8778
    @mitkumamo8778 Před 4 lety

    Very nice lecture

  • @marthagregory8544
    @marthagregory8544 Před 2 lety

    Thank you for sharing

  • @monadir01
    @monadir01 Před 2 lety

    Great video!

  • @oluwaseunawotunde4467
    @oluwaseunawotunde4467 Před 3 lety

    great work

  • @brianneira7479
    @brianneira7479 Před 3 lety

    This is amazing!

  • @josephhubbard4332
    @josephhubbard4332 Před 4 lety +3

    I'm not sure voltage-gated potassium channels opening at the depolarization threshold is accurate. It would have to move against both electrical potential and concentration gradients to make the intracellular potential more positive and literature seems to suggest that it is either calcium or more sodium gates

  • @jamaicacolumbres7154
    @jamaicacolumbres7154 Před 3 lety

    Thanks, help a lot!

  • @yakimabarreravaldes7145

    Thank you so much!! God bless you .

  • @xCrash57x
    @xCrash57x Před 2 lety

    May i ask when is the action potential generated? Surely if the neurotransmitter is inhibitory, it wpuldn't stimulate the voltage gated Na+ and K+ channels to open at all - so what would happen if the summation was overall hyperpolarising? Is this vid assuming the NT is excitatory? I would have guessed the action potential would be generated after the ionotropic channel reached threshold value but im unsure.

  • @timothyvanpelt_cyclist
    @timothyvanpelt_cyclist Před 3 lety +1

    Content of tremendous value, you often fill in the gaps of concepts I'm trying to understand.
    I think one point could be made more clear in this video. Based on most other sources I have, voltage-gated sodium channels only start opening quickly at around -55mV (threshold value) and voltage-gated potassium channels at around +30mV. But, for example in the figure at 10:50, you show and say the potassium channels open at -55mV. I'm trying to get this clear for myself, so maybe this is of help! I'd also like to suggest a video about saltatory condunction in detail! :D

    • @ubimumu
      @ubimumu Před 2 lety

      On God no Cap you right

  • @profkelvinlyatuu863
    @profkelvinlyatuu863 Před 4 lety

    I've understood Prof Dave welcome Tanzania sir at Mt Kilimanjaro

  • @mrsatafrika3109
    @mrsatafrika3109 Před 3 lety

    this is amazing

  • @ngalalizette9175
    @ngalalizette9175 Před 2 lety

    Thanks a bunch

  • @thejaaaa
    @thejaaaa Před 4 lety +2

    Lovin the new haircut!

  • @shikamarunara2827
    @shikamarunara2827 Před 3 lety +1

    Thanks 🙃💜

  • @soumyasakhadas2980
    @soumyasakhadas2980 Před 2 lety

    Thank you sir love from India ❤

  • @fahimrahman3542
    @fahimrahman3542 Před 4 lety +7

    Love from bangladesh🇧🇩

  • @musicloverhayat8402
    @musicloverhayat8402 Před 2 lety

    Thanks💖

  • @user-eu8xd3ux7f
    @user-eu8xd3ux7f Před 3 lety +1

    fantastic

  • @ciscobriano
    @ciscobriano Před 4 lety

    So far 3 videos said to watch another video I should have already watched ! 😊 ok so can you start numbering your videos ??? Please I love your show

  • @malakhamed3885
    @malakhamed3885 Před rokem

    Amazing

  • @dedelsmann1872
    @dedelsmann1872 Před 2 měsíci

    incredible

  • @gilnarrahmoun7194
    @gilnarrahmoun7194 Před 3 lety

    00:25 the signals don't go from hands to spinal cord and then to the brain?

  • @TheHHPodcast
    @TheHHPodcast Před měsícem

    video explanations are a revolution of the education system that used to be based on text for a long time. Couple that with the internet (distribution) and a free market capitalism where the best one gets more spread and voilla: professor dave

  • @adityachakraborty3510
    @adityachakraborty3510 Před 3 lety +2

    This is definitely good stuff exactly the reason why you'll never need a private teacher. XD

  • @lindaurea
    @lindaurea Před 2 lety

    🙏God Bless you for this incredible gift

  • @cesarosorio1057
    @cesarosorio1057 Před 10 měsíci

    gracias te amo

  • @charlotteshi
    @charlotteshi Před 4 lety

    AWESOME

  • @ferielferiel2005
    @ferielferiel2005 Před měsícem

    Thanks from Algeria 🇩🇿✅

  • @zartashakhan6031
    @zartashakhan6031 Před 2 lety

    Amazing vedio

  • @yusuphabah4759
    @yusuphabah4759 Před 7 měsíci

    This man here deserves some novel prize

  • @pritipoddar9025
    @pritipoddar9025 Před 3 lety +2

    Thank you it's very helpful...And you look like Captain America☺☺

  • @omanakuttan6038
    @omanakuttan6038 Před 3 lety

    U are so superrrr sir

  • @charron115
    @charron115 Před 2 lety

    i would fail my course without this..

  • @SherlockHolmes221B.
    @SherlockHolmes221B. Před 4 lety +1

    Sir we loved the old hairstyle.😁
    Awesome explanation though.

  • @nursepotassium
    @nursepotassium Před 3 lety +1

    I thought that
    resting state: Na and K gates closed.
    depolarization phase: Na gates open but K gates still closed
    repolarization phase: Na gates close and K gates open
    Then the Na/K pump: brings in back from hyperpolarization to RMP??????? That's how my professor taught it...is it wrong?

  • @kurrs177
    @kurrs177 Před 2 lety

    is there a transcript of this?

  • @TheHHPodcast
    @TheHHPodcast Před měsícem +1

    since this channel explains things so extraordinary well that either means:
    1. it is for dumb people. Because smart people would not need such good explanations OR
    2. that it is both for smart- and dumb people because it saves all from needless confusion and delay of understanding.
    What do you say? My answer is number 2. Because number 1. Is like saying "nice cars are only for bad drivers because they need all the help they can get". Also: Why would a good driver (smart person) want to drive a bad car (even though he could handle it) if he has the choice to drive a nice car (professor Dave videos).

  • @aleshiukas
    @aleshiukas Před 4 lety +1

    What happens between the membranes ? And why certain diseases which thickens membrane makes slower signaling ?

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  Před 4 lety +1

      Between which membranes? I'm not aware of anything that thickens membranes, I would assume they are of fixed width, as phospholipids are of a fixed length.

    • @aleshiukas
      @aleshiukas Před 4 lety +1

      @@ProfessorDaveExplains At czcams.com/video/zHJ3h675nNk/video.html I can see several membranes/coath, where in-between is a thick area. Or this is just a symbolic image and membrane is thru the whole axon in one piece ?
      As matter membrane thick, there are several demyelination processes regarding neuro diseases (multiple sclerosis, gulian-barre syndrome etc..)

    • @fernsader9261
      @fernsader9261 Před 4 lety

      @@aleshiukas the demyelination would denature both the protein and membrane layers along the mylin sheath layers which would rupture the tissue, therefor affecting the action potential of the cells, and reducing cognitive ability. but all of this if one were to state it the way your trying to understand it, is technically DECREASING the density or thickness of the sheath.

    • @fernsader9261
      @fernsader9261 Před 4 lety

      I am not aware of increases in neuron growth as neuronal cells are stagnant and do not replicate. If they do it is very rare and through the use of extensive oxygen induction.

    • @aleshiukas
      @aleshiukas Před 4 lety

      @@fernsader9261 Im asking why demyelination slows down messages sent along axon comparing the healthy nerve with a normal myelin coath.

  • @thomasruwart1722
    @thomasruwart1722 Před 4 lety +2

    A great book to read about what happens when brain things go wrong is "The Man Who Mistook His Wife for a Hat" by Oliver Sacks (hint: there are pdfs floating around that you can find for free).

  • @h4hashir
    @h4hashir Před 2 lety

    Where’s the neurotransmitter video? Was it ever made?

  • @jayita1523
    @jayita1523 Před 2 lety

    Can anyone tell me what is the need for action potential? Does it help in faster transmission of the nerve impulses?

    • @organizedbiology
      @organizedbiology Před rokem +1

      The action potential itself IS the achievement of electrical transmission-that is, once the neuron reaches its threshold potential, sodium ions will rush in, leading to a rapid transmission of an electrochemical impulse down the axon. It certainly helps the speed of transmission-as does the myelination of those axons, which insulated the signal and makes it go faster, similar to wires in our homes.

  • @SCIPROlearning
    @SCIPROlearning Před 3 lety +1

    👍 great

  • @yourfavouritescepticx8969

    I come ere when I can’t be asked to read the textbooks although I still end up reading it because I learn best from multiple sources with the same ideologies 😃