How weak do your muscles get with bedrest?

Lack of gravity during spaceflight, and also injury and bedrest here on Earth can cause loss of both muscle size and strength. How much and how quickly does this happen, and does the rate of weakening change?
Created by Stephen Cheung, Ph.D., Director of the Environmental Ergonomics Lab and Professor at Brock University ( / eelbrock .
Paper discussed:
Marusic U, M Narici, B Simunic, R Pisot, R Ritzmann. Nonuniform loss of muscle strength and atrophy during bed rest: a systematic review. J Appl Physiol. 131(1):194-206, 2021,
Graphic created using BioRender.com. Photo by The New York Public Library on Unsplash.

[@mateospeciel8475]

Wow im currently doing a paper on ways to prevent muscle atrophy during long term bed rest and had this specific paper as one of my main sources cant believe theres actually a video on it too!
i was wondering: what would be the best protocol during and after long term bed rest to minimize atrophy?

[@kbb8962]

How can.elderly.newfound regain their strengths to regain ability to walk!