How to Mix Hyaluronic Acid at 2%
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- čas přidán 11. 09. 2024
- Mixing Hyaluronic Acid
Hyaluronic acid is a natural polysaccharide (large sugar molecule) that occurs in various tissues (skin, synovial fluids of joints, connective tissues). Responsible for tissue hydration, lubrication, & tissue stability, holds 500 times its own weight of water. In skin care it is a powerful moisturizer & humectant that provides smoothness & softening to the skin. Can reduce the appearance of wrinkles.
We carry two different types:
-High Molecular Weight Hyaluronic Acid (HMW HA)
-Super Low Molecular Weight Hyaluronic Acid (SLMW HA).
The High Molecular HA will create a thick gel and 2-3% is probably the maximum concentration you can dissolve.
The Super Low Molecular HA will stay a liquid to slightly viscous solution even at 8% concentration. Its advantage is that a higher concentration can be incorporated into formulations. However if you're looking for added viscosity and a concentration between 1- 2% is fine then the HMW HA is the one to use.
We're going to show you how to dissolve the HMW Hyaluronic Acid. In order to mix this fine powder with water you will need a stick blender, sheer mixer or homogenizer.
This video shows how to make a 2% Hyaluronic Acid concentration using HMW HA.
Step 1: Add 98.8g / 3.55oz of distilled water and 1.2g of Phenoxyethanol-SA to a disinfected glass beaker.
Step 2: Sprinkle 2g / 0.07oz HMW HA into the water. Mix well using a stick blender.
Step 3: The solution becomes very thick.
Step 4: Keep mixing until there are no visible lumps.
Step 5: If you want to keep this mixture, as a stock solution, add a preservative such as phenoxyethanol or benzyl alcohol.
Ingredients used:
Distilled Water
HMW Hyaluronic Acid
Phenoxyethanol-SA
For more information on the Hyaluronic Acid visit our website at www.makingcosmetics.com!
after blending, hyaluronic acid loses its properties and, above all, its viscosity. The acid should not be mixed faster than 300 RPM because it breaks the long acid bonds and must not exceed 35 degrees at any time because it also leads to the breakdown of bonds.
2% hyaluronic acid should have a viscosity of about 20-100 times higher than honey (depending on what honey viscosity we take ranges from 2Pa to 10Pa). Your ... something will not help more than pure water
unless the movie was to be called How NOT to mix hyaluronic acid
is this accurate? @MakingCosmetics
@@BrownOpsLeak I can assure you it is, rest of the comments are out of their ass
as far as I know, hyaluronic acid doesn't benefit from contact with metal... you can simply shake well in a jar using cold water...
Excellent information, but the video could use a better audio. Thank you for the written info under the video!
If you wanted to add this to a finished cream/Serum, what percentage of this Hyaluronic Acid Gel blend would you need?
Can you make a video on how to make injectable hyaluron is aci
Theoretically, you can add pure hyaluronic acid to a makeup powder, but it won't be effective since hyaluronic acid has only a moisturizing effect when combined with water.
Hey plzzz tell me how much HA powder I need to make 30ml 2% HA acid?? Plzz reply
The molecular weight is 800-1200kDa. It won't penetrate the skin.
What about the hair?
The blending was on fleek haha... hopefully the long molecular chain of the HLA stays intact after being treated so aggressively. :'D
Also I have been taught that more than 1% by volume HLA has the opposite effect on the skin, ie instead of being a super effective moisturiser and humectant, it starts to draw moisture FROM the skin which is obviously the opposite effect we want.
Most of the time a 2% HA (high molecular weight) solution will be used as a stock solution and added to a formulation at a certain percentage - so it will be diluted greatly and not be used on the skin as is. When used at the skin as is, it may flake off due to the high concentration, it works best when mixed with other ingredients or mixed into a formulation.
MakingCosmetics
yeah thats how I like to do it too! I mix the hyaluronic acid powder is DI water and shake from time to time until its jelly in about 3 hrs. Then mix it in with other goodies like aloe vera juice, licorice root extract, etc. Love HA on the skin lol
@@candacelin4115 thanks for the info! I was trying to know if I can mix it with something else.
@@Makingcosmetics can I combine it with vitamin c and extracts, but oils right?
Candace can u kindly tell me other ingredients u mix inside... thanks
Hyaluronic acid powder has a shelf life of 2 years. You certainly can still use it.
Please click on the "SHOW MORE" link above, then you'll see all the details including concentrations.
It's not shear-sensitive? Some say the high shear is bad for HA.
So I have a couple of questions,
How long will the mix last without preservatives?
Also, if I want to mix large quantities, should I use a homogenizer or agitator?
Without preservatives the shelf life is typically about 2 weeks. For large quantities we recommend to use a homogenizer.
Wont you destroy the molecule of HA by mixing it with a high sheer homogenizer or blender?
Hi I have Hylauronic acid HMW powder and want to add it to creams and lotions. Do I make this solution and then use 1-2% of the solution to my water phase or do I make the solution and add the entire solution to 1 lotion?
Regular Hyaluronic acid (www.makingcosmetics.com/Hyaluronic-Acid_p_161.html) is a bit tricky to integrate into a base. It does not readily dissolve in water but needs to be carefully sprinkled into some water first under constant high-speed stirring (preferably with a hand mixer or vortex mixer). Typical concentration is at 0.1 - 2% of HA. The mixture starts then thickening quickly and becomes a gel. At that point no additional HA can be added as there is no water left for HA to be dissolved in (additional HA would only form lumps). Only this gel can then be added to the serum.
Depending on the composition of the cream or serum, I'd try to add about 5-10% but not more as the emulsion of the cream could be destabilized.
Can I use some tightener or stem cell extract in it?
@@laurag.5344 As long as these ingredients are water-soluble, it's possible.
Is this enjacteble to enhance breast or buttock?
Can i use preservative called ' Lucidel Liquid Complete 'to add for longer shelf life and what is the Ratio of a preservative need to be used making this batch you made in this video??PLZ help
You can try using this preservative, please ask the seller for the appropriate concentration that you need to use. Then make a microbial test (available on our website) 7 days after completion, 14 days after completion and 1 months after completion. This will tell you if there are microorganisms growing in the product or not. If there is growth, you will need to add or switch to a different preservative.
What is the ratio of hyaloronic acid to distilled water, if I was to make a batch of it for 375 (amount) of
10ml / .3 fl oz (sized) product tubes
Or you can just put it in the distilled water and it will become a gel within hours
Where are the specific measurements?
The measurements are in the description below the video.
hello, a few months ago buy hyaluronic acid powder with you, I have a doubt, could you tell me how much time is expired? please
2 years
this need refrigerator for preserved?
Hi there,
If any one can answer this please do.
I made the 2% solution and it all went well. A week later the mixture has become watery and not thick and viscous. Did I do something wrong?
Please and thank you!
hello i am really interested in all what book can you recomend for know a little more
Is this safe to apply directly to the skin, after mixing?
Yes, absolutely. You can apply the gel to skin.
@@Makingcosmetics
correctly prepared, good quality 2%Ha will dry out your skin quickly, sorry
hi!
What is the molecular weight of the Hyaluronic Acid powder for skin serums? i mean in daltons. i know its not suppose to be high for it to penetrate, and if its too low it causes inflammation and therefore not good for you...so what is the best number in your opinion?
and how long does it last at its best shape without preservatives?
We carry High molecular and low molecular Hyaluronic Acid, but only the high molecular HA will have a thickening effect. Please check specific data on our website www.makingcosmetics.com. Thank you.
MakingCosmetics I dont know what you mean by thickening effect, but i will be grateful if you could answer my few questions, there is no info on your site, only links to products.
You see in the video that 1-2% HA High molecular weight, will form a gel, while the Low Molecular HA will not do that.
MakingCosmetics o.k, that i know.. but what about my questions??
HA serum without a preservative will only last a matter of hours, and possibly 48 hours. The high molecular weight of HA will penetrate the epidermis (top layer of skin), but it's a slow process. The low molecular weight is costly and, as far as I can tell, I don't believe it worth the cost. The actual Dalton number is not so important as the labeling of High Molecular Weight and Low Molecular Wright. Where did you get the info that claims HA will irritate if its MW is too small? You can check out the Dalton difference of HA that Making Cosmetics sells.
Hello.I'm a doctor.can we inject home made HA to lips or other areas?
No, our HA (www.makingcosmetics.com/Hyaluronic-Acid-ECOCERT-Approved_p_161.html) is for external use only.
Beautiful. Thank you.
Can you use this mixture with a hyaluron pen?
We did not test it for that application.
have you found anything that works for the ha pen crosslinked that would last?
Hi there. Is adding just phenoxyethanol enough? Or i have read that adding caprylyl glycol with sorbic acid or potassium sorbate necessary? if so, what proportions? if i add in just phenoxyethanol, whats the shelf life like, and if i add in phenoxyethanol and potassium sorbate, does shelf life increase? many thanks!
Phenoxyethanol is certainly enough. Typically it is used at a concentration of 1%
Its not 2% is 1% , cause the effectiveness of the solution (HA ). T
HATS a lot of molecular weight. no good ! 1% and the refrigerated for 48 hrs . No liquid like
you said in the video !
Am i able to use this in a makeup powder?
20% is way too high. 2% is the maximum.
MakingCosmetics can u please give us it in teaspoons or tablespoon
I thought the max was 1%?
Is good for mesoterapy or derma pen????
Is it possible to use a direct substance?
I made mine but how much percentage of the gel can I add to my lotion base ?
Depending on the type and composition of your lotion you can add between 1-10%.
@@Makingcosmetics thank you very much😊
Which one is the best to use.Please answer, because I want to purchase ASAP. THANKS
For making a hydrating gel we recommend to use this one: www.makingcosmetics.com/Hyaluronic-Acid_p_161.html
Can you tell us the amount of water and how many grams of powder the link please again resend with information would be appreciated. I don’t see the link you mentioned in show more. Thank you.
Click on the SHOW MORE link above then you see the entire recipe.
How long does this last without preservative?
Do you recommend keeping in the fridge without preservative? I also purchased Phenoxyethanol-SA what percentage should I use it and how long will it extend the shelf life?
Without preservative the shelf-life is about 1-2 weeks. With phenoxyethanol-SA about 6-12 months.
Good day, are you able to use this formula as is directly onto skin?
Yes, you can use this directly on the skin. We do recommend adding a preservative if not used up within a few days.
Hi! I wanted to know could you make a batch of each HMW and SLMW and then mix them together to obtain the benefits that both of these molecules produce?
Yes, you can combine regular and low-molecular weight HA in the same formula. No problem.
HOW MUCH OF THE 2% SHOULD I DRINK A DAY? 2 TABLESPOONS TWICE A DAY?
Hello, thank you for your comment.
This is a cosmetic product for topical application and not for ingestion.
Hi there! I did this and came to a very thick gel consistency I'm just wondering now how do I scale that in formulas?
Hello, thank you for your inquiry. If your goal is less viscosity we suggest to use 1% Hyaluronic Acid, if you like to keep it at 2% we suggest to use SLMW HA (low molecular weight) which doesn’t increase the viscosity much. HMW and SLMW Hyaluronic acids can also be combined to find the viscosity that works best for your formulations.
Showing. But telling us the weights? But why....
Great! If I use EuxylPE9010 at 1% will it change anything? I plan on using HA at 1500-2000 kDa, in this case should I lower the HA content to 1 or 1.5%? Cheers!!!
EuxylPE9010 shouldn't interfere, theoretically. Low-molecular weight HA can be dosed at higher concentrations (up to 10%).
So what can we do with this aside from putting it on directly on our skin? Can we add some essential oils, others powders to it like vitamin C or to a facial moisturizer?
You could add additional ingredients but only ones that are water-soluble. If you want to add oils you'd have to add an emulsifier, too, to make an emulsion (cream, lotion).
@@Makingcosmetics got it! Thx for your reply 😁
If I make any kind of cosmetics with Hyaloronic Acid, what kind of preservatives I need to add?
We'd recommend to use 0.5-1% of phenoxyethanol-SA
If I add this mixture to my product that already has a significant amount of water, will the ratio and therefore the effectiveness be changed?
If you add, let's say 10g of this solution to 90g of cream, then the hyaluronic acid will be diluted 10 times.
If i want to sell it, do you need to add caprylyl glycol as an antibacterial, or not?
Adding a preservative is highly recommended if you want to sell it.
Can i mix hyaluronic acid powder with DMSO? Or will I need to constitute the HA powder before mixing with DMSO? What ratio of HA to DMSO??
When I did this, I dissolved the powder at 1% in water first then added 10% Dmso to increase penetration to treat wrinkled hands.. but I didn’t apply anything else cos of the disadvantage of Dmso transporting almost everything into the skin. it worked… maybe this may help..
We just need to wait for 2 hours for desolve nothing else
thank you for your video, you didn't adjust the pH, did you? Should I adjust the pH, or it can be higher? thank you....
pH should be in the range of 4-6
@@Makingcosmetics 🤗
@@Makingcosmetics then, how the ph of the ordinary HA 2%+ vit B5 serum is from 6 to 7.5?
Can I used vitamin C as preservative? I plan to mix it with Aloe Vera gel
You can add vitamin c as antioxidant but it doesn't have any anti-microbial (preservative) function
Can this be taken orally? If so, how much? Thank you xx
No, that is for external use only.
Do you have any recommendations for mixing 45 gallon batches? Do we need a homogenizer?
Yes, you'd definitely need a homogenizer.
Can you apply the above solution directly on to your face, will it not draw water from your skin and make it dry instead.
You can and yes it would but it’s better to have moist skin before using HA, that way the water on your skin gets brought below the skins surface and can hydrate that way
Yes, you can add this solution directly to the skin, but in general we recommend to incorporate hyaluronic acid into a cream or lotion.
Thanks goldie and thankyou making cosmetics for you kind and helpful reply, it would be appreciated if you can kindly let me know the ratio if we mix it in a face cream or moisturiser or lactocalamine solution.
@@Makingcosmetics what is the percentage ratio to mix in face cream, moisturizer and lactocalamine solution, plz kindly help.
About 10-15%
How do you get rid of the bubbles after using the stick blender?
To avoid bubbles, make sure that the stick blender is fully submerged in the liquid. If the stick blender runs at the surface air is being trapped into the liquid creating a lot of bubbles which are hard to remove.
Hi i have a hyaluronic acid serum that’s like a syrup consistency is there a way to make it like a thinner liquid without diluting it too much?
You could try to add a little distilled water and stir thoroughly.
Is this for external of internal use?
For external use only (for skincare products)
@@Makingcosmetics I suggest that be your title.
@@bobcatt2294 did you see the channel’s name is “making COSMETICS” you don’t eat cosmetics!
@@buttercup9903 However a channel may also include health tips. Again, should be in the title. Use the word, "Skin" within the title.
@makingcosmetics
if we ad phenoxyethanol to the solution. what would be the shelf life of this solution
Depends on how clean your work and what the water quality is, but typically 9-18 months.
Is switching to benzyl alcohol as the preservative the same ratio as phenoxyethanol? Thanks!
Benzylalcohol-DHA is dose somewhat lower at 0.4-0.8%.
@@Makingcosmetics ThankU! Is it pure benzyl alcohol or a mixture with a secondary preservative? I see there's a version that's mixed on your website, just want to be totally sure to be safe! I have several ingredients from your company, but not my BA. ✨
Thank you so much for the informative video. This is really great. Can you please tell the company and the model number of the handheld blender?
It's a regular KitchenAid blender (www.kohls.com/product/prd-949338/kitchenaid-khb1231-2-speed-hand-blender.jsp?ci_mcc=ci&SMALL%20ELECTRICS&CSE&CID=shopping20&gclid=CLHpw46whN0CFcHdDQodJewLYw&gclsrc=ds&dclid=CLfE0I6whN0CFQUGgQodPZEDXA)
do you have promo codes on your website? thank u
Hi, thank you for your inquiry. Currently, we do not have any running promo codes. Sign up for our e-newsletters to stay up to date on all of our sales though! You can sign up here: www.makingcosmetics.com/. Just scroll all the way down to the bottom of the page!
is this safe to inject?
No, that's for external use only.
Hello, can you place tell me how I can mix this acid in my body cream?.
Thank you
Hyaluronic acid needs to be carefully sprinkled into some water first under constant high-speed stirring (preferably with a hand mixer or vortex mixer). Typical concentration is at 0.1 - 2% of HA. The mixture starts then thickening quickly and becomes a gel. At that point no additional HA can be added as there is no water left for HA to be dissolved in (additional HA would only form lumps). Only this gel can then be added to the serum or cream.
I am a layman's ,
to my knowledge two different type of moisture are there , water base & oil base ( oils are always uses as massage ) but HO is water soluble & it can absorb water ( not oil ) into skin & so not to be mixed with oil . Body cream has Vaseline base with added oils. body lotion are moisturizer which can protect ( block the skin from ) toward external elements whereas HO absorb moisture into the skin. So it is wise to use both as separate parts one & part two ( oil block water absorption into / out of the skin )
how do you mix phenoxyethanol to this HA?
You have to determine the weight of the batch you're making then add between 1.0-1.5% of phenoxyethanol/SA by weight and blend well.
Hi. My hyaloronic acid power is not desoliving in water. What could be the reason of that?
High-molecular weight hyaluronic acid (HA) does not readily dissolve in water as it binds water very quickly. Thus, HA needs to be carefully sprinkled into the water under constant high-speed stirring (preferably with a hand mixer or vortex mixer). Typical concentration is at 0.1 - 2% of HA (1g of HA and 100ml of water). The mixture starts then thickening quickly and becomes a gel. At that point no additional HA can be added as there is no water left for HA to be dissolved in (additional HA would only form lumps).
What is Phenoxyethanol-SA?
Phenoxyethanol-SA is a preservative to prevent bacterial contamination.
Highly toxic for you brain!!
Can I mix hyalorunic acid with glycerin, I want to combined with a lip gloss
Not sure whether hyaluronic acid dissolves completely in glycerin. If it doesn't, I'd try a glycerin/water mixture
Great video! Can this be made into more of a watery liquid not so much a serum or gel? If so , how long is it good for if mixed this way? Thanks
You'd have to use a different form of hyaluronic acid (www.makingcosmetics.com/Hyaluronic-Acid-SLMW_p_162.html) if you don't want to make a gel but a watery solution.
@@Makingcosmetics Thanks so much for the response. Im trying to safely make solutions for my hydrafacial machine and everything needs to be in liquid form. I found all the ingredients on your site and ready to purchase. Im just confused on how to safely make it. Would these types of solutions be in your book of formulations? I really appreciate your time thanks.
I suggest that you first check out our free formulary page (www.makingcosmetics.com/Formulas_ep_5.html).
Pls can I use Vit B3 in place of Vit B5, thanks
Yes, you can use vitamin B3 instead of B5. Both are water-soluble.
How can i order it organic ingredient for hair cream,i am in Nigeria edo state pls reply me
Unfortunately, we don't ship to Nigeria.
If u want I can oder it for an Waybe it for u am into skin 08139703562
What kind of hialuronic acid is that?
It's this: www.makingcosmetics.com/HUM-HYAL-01.html?lang=default.
Its possible for inject with needle ?
No, this is only for external, topical use.
Put a teaspoon or tablespoon
Since the weights for the ingredients are so small tsp or Tbsps would be too inaccurate.
wait a min can somebody tell me what she added at the begning is that water?
Yes, distilled water.
is hyaluranic acid powder same hyaluranic acid pills?
This form of hyaluronic acid is exclusively for cosmetic use and cannot be taken internally.
@@Makingcosmetics thnx for reply ! Can I turn the pills to powder and turn powder to liquid? for cosmetic
Maybe, I don't know what kind of pills you have and what they are made of. But you can buy hyaluronic acid powder here: www.makingcosmetics.com/Hyaluronic-Acid-ECOCERT-Approved_p_161.html
Not giving any exact measurements, water amount, Hyaluronic amount?
Click on the 'SHOW MORE' link above to see the complete recipe.
I am lost...
@@melissiawilliams2536 Left at Bleecker Street.
That was so unsanitary. I wouldn't let the bacteria that came off of that blender anywhere near my face.
you need to speak up during a presentation...
First