Canonical NF-KB pathway | NF-KB Pathway | Classical NF-KB Pathway: Mechanism of Signal Transduction
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- čas přidán 2. 11. 2019
- This video lecture explains NF-KB pathway with emphasis on canonical/classical NF-KB pathway. The mechanism of signal transduction in canonical NF-KB has been explained in detail. #CanonicalNFkBpathway #CanonicalNFkBpathwaySignaling
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Very good explanation! that's a great professor!
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Wow, just about to start planning for my dissertation and I'm gonna do it on nfkb and this has been such a huge help. Thanks so much
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Excellent video prof. Thank you very much for the upload 😊😊😊😊
Thank you for your valuable comment. I am happy that this video was helpful to you..
Nice video professor
Thank you.
Thank you for uploading video
Thank you. I am happy that this video was a bit of help for you. Please keep liking, and sharing my videos....
REALLY EXCELENT EXPLANATION !
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whoaa thankyou so much i really understand your simple explanation and animation thankyou so much
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From all papers that I have read, as well from the video's information at 2:28, the other name for p65 is RelA. So then, why is it that in your diagram, the other name for p65 is written to be c-Rel. That seems incorrect to me, but maybe there is a better explanation. Could someone please clarify?
You are absolutely right that the other name for p65 is RelA. Our explanation for p65/c-Rel is as below.
NF-κB is formed through the homo- or hetero-dimerization of members of the Rel family of DNA binding proteins. In mammals these include RelA (p65), c-rel, RelB, p105 (the precursor of p50), and p100 (the precursor of p52). P65/c-Rel shown in the picture in the video, is the NF-kB formed through c-REl and p65. Please let us know if you need further explanation. Thank you.
@@BiologyLectures Thanks for your explanation. I was wondering about the same thing.
Nice
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