2-Minute Neuroscience: ADHD

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  • čas přidán 11. 02. 2022
  • ​Attention-deficit/hyperactivity disorder, or ADHD, is a condition characterized by difficulties with attention and/or hyperactivity and impulsivity. In this video, I discuss perspectives on the neuroscience of ADHD.​
    TRANSCRIPT:
    Attention-deficit/hyperactivity disorder, or ADHD, is a condition characterized by difficulties with attention and/or hyperactivity and impulsivity. ADHD involves strong genetic influences, but environmental factors, and interactions between genetics and the environment, are thought to play an important role in ADHD as well.
    Much of the recent research into the neuroscience of ADHD has focused on understanding the brain networks that might underlie different aspects of cognitive function in ADHD. One example is the default mode network, which is a collection of brain regions that is more active during mind-wandering and introspection, and less active when a person is attempting to complete a specific task. Studies have found that people with ADHD have atypical connectivity in the default mode network, which might be associated with distractibility.
    Individuals with ADHD also display lower activity in brain networks that are involved in attention and cognitive control. Typically, activity in these networks increases when activity in the default mode network decreases, and vice versa. Thus, one hypothesis is that in ADHD activity in the default mode network is dysregulated and interferes with the function of networks involved in attention and cognitive control.
    Studies have also found that people with ADHD tend to display atypical activity in the reward system, a group of structures that are involved in motivated behavior, anticipation, and reinforced learning. This atypical reward system activity might be associated with a tendency to overestimate the value of short-term rewards in comparison to long-term rewards, which could also affect planning and decision-making. The reward system includes some of the major dopamine pathways in the brain, and dopamine is often implicated in ADHD because medications that are commonly used to treat the condition, such as amphetamine and methylphenidate, cause increased transmission of dopamine and norepinephrine.
    REFERENCES:
    Faraone SV, Asherson P, Banaschewski T, Biederman J, Buitelaar JK, Ramos-Quiroga JA, Rohde LA, Sonuga-Barke EJ, Tannock R, Franke B. Attention-deficit/hyperactivity disorder. Nat Rev Dis Primers. 2015 Aug 6;1:15020. doi: 10.1038/nrdp.2015.20. PMID: 27189265.
    Gallo EF, Posner J. Moving towards causality in attention-deficit hyperactivity disorder: overview of neural and genetic mechanisms. Lancet Psychiatry. 2016 Jun;3(6):555-67. doi: 10.1016/S2215-0366(16)00096-1. Epub 2016 May 13. PMID: 27183902; PMCID: PMC4893880.
    Posner J, Polanczyk GV, Sonuga-Barke E. Attention-deficit hyperactivity disorder. Lancet. 2020 Feb 8;395(10222):450-462. doi: 10.1016/S0140-6736(19)33004-1. Epub 2020 Jan 23. PMID: 31982036; PMCID: PMC7880081.
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Komentáře • 264

  • @omarbadran7225
    @omarbadran7225 Před 2 lety +450

    ADHD is a misnomer that most scientists in the field want to change to something like executive function disorder. And the reason they are not changing it is mostly politics inside the DSM committee. It's way more complex than blaming a neurotransmitter or a network. I have treatment resistant ADHD and been researching and trying medications since I was 14, and now I'm 22 and barely started to see improvements after trying every f'ing psychoactive drug available in my country. I'm a software engineer and I have nothing to do with biology, but here is a small explanation from what I understand about the disorder:
    As for the dopamine hypothesis, research does show that ADHD has a lot of dopaminergic abnormalities, but that does not explain a lot. It also contradicts with a lot of other facts that we know about ADHD. For example, some ADHD drugs (e.g. Intuniv) and most of the ones that are being developed right now barely touch dopamine at all. And most of Parkinson's drugs that increase dopamine either don't show any benefit or a very small one and only rarely used to augment stimulants (i.e. amantadine). So how would the dopamine hypothesis explain that? And how do we explain the fact that drugs such as stimulants which are insanely powerful at increasing dopamine only helps about 80% of patients and out of these about 40% of them don't get full symptomatic relief. And how does the DMN abnormality explain a lot of the symptoms such as emotional dysregulation, time-management problems, delayed circadian rhythm phase (Up to 75% of adult patients), and motor coordination problems which are present in most ADHD patients?
    It's a very long subject, but the most recent explanations of ADHD is that it's an executive function disorder that affects all the functions related to goal-directed behavior. You can think of attention as the navigation system of your brain, that is always scanning the environment and once a stimulus is relevant to a goal, your brain releases dopamine which then increases the silence of that stimulus, which shifts your attention to it and allow you to sustain your attention and helps you problem-solve that task using your other executive functions (i.e. manipulating the environment according to your goals). And along this process, there are multiple parts of your brain that each has a role in this system. For example, if you get distracted by something that has an emotional component to it (i.e. anger at a coworker) usually the DLPFC is the part that allows you to inhibit that automatic response if inhibition was the preferred long-term response according to your goals (i.e. not getting fired). Now if the distraction is something such as an idea to go do something more rewarding (watch CZcams videos), then other parts of the PFC engage in a coordinated way to inhibit that behavior and go back to the task at hand. And the list goes on for other processes related to executive functioning such as planning, prioritizing and sustaining, and shifting attention, regulating alertness, and processing speed.
    So when we treat ADHD, we do our best to shift this abnormal connectivity closer to normal as much of that as possible. And this abnormal connectivity is slightly different for each patient, as ADHD is a "highly complex and heterogeneous disorder".
    Now obviously stimulants play a huge role which is why they are the first line medications, but most of the time patients need a combo of drugs such Intuniv+Stimulant, Strattera+Stimulant, Qelbree+Stimulant, etc. So that we cover as many affected areas as possible. And we have new drugs being developed that target totally different systems, such as H3 antagonists like Betahistine, and Nicotinic agonists like ABT-089.
    CBT also plays a huge role, although not very effective without medications. But studies show that the combination of CBT and stimulant treatment is more efficacious than either alone. And not any form of CBT, only the one designed specifically for ADHD, such as the ones developed by Russell Ramsay or Mary Solanto.
    Here is a good start:
    www.sciencedirect.com/science/article/pii/S014976342100049X
    www.russellbarkley.org/factsheets/WhatCausesADHD2017.pdf (a bit old)
    www.russellbarkley.org/factsheets/ADHD_EF_and_SR.pdf
    www.sciencedirect.com/science/article/abs/pii/S2451902220300483
    (This wall of text is proudly brought to you by Ritalin)
    (Also, fuck, I should be working right now)

    • @omarbadran7225
      @omarbadran7225 Před 2 lety +9

      Why the fuck did I just write that? I'm high as fuck.

    • @joneriksen9257
      @joneriksen9257 Před 2 lety +52

      @@omarbadran7225 the wonders of ritalin, mixed with the interest of a intensily curious person trying to be better.

    • @solanumtuberosum5869
      @solanumtuberosum5869 Před 2 lety +13

      Wow, thank you for sharing this

    • @Willie6785
      @Willie6785 Před 2 lety +23

      @@omarbadran7225 can absolutely relate lmao. I take vyvanse and the urge to write huge walls of text, especially as someone who's very interested in expressing their thoughts fully (maybe even an adhd thing lol), is huge sometimes.

    • @omarbadran7225
      @omarbadran7225 Před 2 lety +27

      @@Willie6785 Yeah it happens a lot. If I take my meds and they kick in while I'm doing something I'm not supposed to be doing, it gets really hard to shift my attention to something else especially if it's something that I enjoy. Meds are a double edged sword.

  • @amtahboub
    @amtahboub Před 2 lety +462

    This is extremely validating.. ten years on I still feel like a fraud when I go to my psychiatrist for ADHD

    • @AngDevigne
      @AngDevigne Před 2 lety +17

      Solidarity.

    • @hanskraut2018
      @hanskraut2018 Před 2 lety +3

      Stop getting yr information from fringe psychiatrists or not well known experts and the least from opinion channels of mild ADHD or self-diagnosed or s.c.t. people making up stuff to further there own goals or guessing based in personal intuition

    • @tk-zh3dd
      @tk-zh3dd Před 2 lety +7

      Check out Dr Russel Barkley’s videos. He provides much more info about the concepts discussed here. It’ll change your life.

    • @docwiz
      @docwiz Před rokem +8

      @@hanskraut2018 not quite what the point OP was making. Just seems like a missed point.

    • @ErikTheWiz
      @ErikTheWiz Před rokem +9

      After learning more about ADHD I definitely think we should stop allowing psychiatrist to diagnose people, because ADHD is far beyond just simply behavior, it’s neurological.

  • @dontbeabutt7786
    @dontbeabutt7786 Před 2 lety +41

    I had to watch this like 4 times because I kept looking at the sidebar but after the 4th time I was very validated thank u

  • @powerpuff_avenger
    @powerpuff_avenger Před 2 lety +126

    I got tested for ADHD once (in 1 day) and they said I didn't have it, despite constantly fighting mentally to compete the tasks given to me. Most of the time, it takes A LOT of energy to focus and I find myself just "gone", staring blankly at my screen when reading something or following an online class. The movements of the teacher in an on site class keep me focused a little bit better (especially when there are no windows I can easily stare into without going owlish with my neck). I can be pretty impulsive (I will think I've thought about a decision long enough, no one else really agrees lol). I'm getting re-evaluated for autism/ADHD atm, we'll see how that goes...

    • @Tay-wj9et
      @Tay-wj9et Před 2 lety +18

      Good luck! I got tested for aspergers at 16 and they said I didn't score highly enough on the one questionnaire they gave me. Fast forward ten years and after an extensive evaluation and many, many questions, I got diagnosed with autism. Sometimes you just slip through the cracks of the system and you have to try again to get the right answer.

    • @powerpuff_avenger
      @powerpuff_avenger Před 2 lety +10

      @@Tay-wj9et thank you! Yeah I actually had high enough test results but due to my age they didn't want to confirm, but neither reject the possibility... This time my mum also had to fill in a questionnaire about my childhood, so that seemed more promising!

    • @Tay-wj9et
      @Tay-wj9et Před 2 lety +4

      @@powerpuff_avenger definitely more promising if they sought a second opinion and actually looked for evidence from your childhood! I also got diagnosed with ADHD and they did the same for me, my mum and I had to fill in the same questionnaire online so they could compare our answers.

    • @Professor_Brie
      @Professor_Brie Před rokem +7

      When I was going through my diagnosis as a kid, initially the neuropsychologist didn’t think I had it, because I’d performed well on the computer test they gave me. My mom, however, pointed out that the computer test was probably fun for me since it was like a game, so yeah I’d be able to focus well on it. After she explained to him all of the behaviors and struggles I had at school and at home, which this man couldn’t see for himself since he only interacted with me at wherever it was I went to be diagnosed, he decided to follow her judgement, because luckily he was wise enough to understand that my mother knew me way better than he did, and he could tell she knew what she was talking about. I’m thankful for both my mother, and the neuropsychologist who understood that while he was the expert in the science, my mother was the expert on me.

    • @michaela_rose_
      @michaela_rose_ Před rokem +6

      other mental health disorders can have similar symptoms to adhd as well. dealing with childhood trauma, for example, can lead to issues focusing and being present, impulsivity, zoning out/dissociating and feeling exhausted from completing daily tasks as well. you totally may have adhd though, and regardless getting multiple opinions from various mental health professionals could help ensure your struggles are being heard and diagnosed accurately.

  • @zach8483
    @zach8483 Před 2 lety +12

    That was a wonderful watch, it feels extremely validating to see someone so elegantly explain what I couldn't put into words for a long time.

  • @darthrincus
    @darthrincus Před rokem +32

    ADHD is scrolling through the coments while the video is playing

    • @ADHDreamy
      @ADHDreamy Před měsícem +1

      THIS!!

    • @oleg4260_
      @oleg4260_ Před měsícem

      Damn, I literally just opened the video and started scrolling the comments immediately

    • @milox875
      @milox875 Před měsícem

      Yessir 😂

  • @eleksitia
    @eleksitia Před rokem +5

    I just finished watching the video on Autism Spectrum Disorder, your video on Restless Leg Syndrome, and now this video on ADHD (in that order)
    I have all three of these,
    I also enjoyed the videos. The short form format helped me keep my attention on them.

  • @muhammedcagrkartal9954
    @muhammedcagrkartal9954 Před 2 lety +8

    man the content is great
    please start doing cognitive neuroscience videos as well.

  • @scottw550
    @scottw550 Před měsícem +2

    I had ADHD in 1961 at St Pacal's Catholic School in Toronto, Ontario and my Nun teacher tried to beat it out of me with the strap, Scott, "Are you ready for your daily strapping?" but this dosen't even compare with the abuse dished out at the Residential Schools in CANADA on the indigenous young people at the time.

  • @levelthefield
    @levelthefield Před 2 lety +6

    Your videos are amazing! Thank you for introducing me to the field of neuroscience in an unintimidating and fun way!

  • @AngDevigne
    @AngDevigne Před 2 lety +4

    OMG!!! So happy you posted this. Thank you.

  • @aamirrazak3467
    @aamirrazak3467 Před 2 lety +103

    Great video I feel i learn something new every time I watch one of your videos! If ADHD involves deficits with dopamine, I wonder if treatments for Parkinson’s which involves destruction of dopaminergic neurons, could help alleviate symptoms of adhd

    • @AngDevigne
      @AngDevigne Před 2 lety +4

      You know, I've been asking the same thing...

    • @SpererGameplaysH
      @SpererGameplaysH Před 2 lety +2

      Keep me updated

    • @ericastrong2593
      @ericastrong2593 Před 2 lety

      probably depends since the loss of DAergic neurons is in the substantia nigra for parkinson’s and adhd is thought to affect other parts of the brain

    • @smason9157
      @smason9157 Před 2 lety +1

      Side effects are probably not worth it tho tbh

    • @neurochallenged
      @neurochallenged  Před 2 lety +38

      Treatments for Parkinson's tend to have side effects that would likely outweigh any potential benefits for ADHD patients. These can include things ranging from sleepiness to compulsive behavior to movement-related issues. ADHD meds increase dopamine activity, but they also have other effects that likely contribute to their attention-promoting benefits. I would imagine they would be more effective than straight up dopamine agonists or drugs like L-DOPA when it comes to ADHD, with far fewer side effects.

  • @adhdright2158
    @adhdright2158 Před 2 lety +4

    This is so good!! Such a clear explanation!!

  • @mr.glizzy9903
    @mr.glizzy9903 Před 2 lety +3

    I can already tell this video is good

  • @iyar220
    @iyar220 Před 2 lety +1

    I've been looking for this!

  • @TryWithKev
    @TryWithKev Před rokem +1

    Fantastic description.

  • @jacksonmajor2663
    @jacksonmajor2663 Před 2 lety +3

    My foundations of behavioral neuroscience teacher plays your videos in class

  • @topalaluiza9647
    @topalaluiza9647 Před rokem

    Thank you so much 🙏🙏🙏

  • @elywood3075
    @elywood3075 Před 2 lety +9

    If you believe you may have ADHD inattentive type or are treatment resistant, look into sluggish cognitive tempo.

  • @ADHDreamy
    @ADHDreamy Před měsícem +1

    Really great stuff, thank you!

  • @theJellyjoker
    @theJellyjoker Před rokem +1

    I have ADHD but I'm not hyperactive, the H in ADHD is why I did not seek treatment for so many years.

  • @Brandon-tz5pn
    @Brandon-tz5pn Před rokem +1

    Got to the end of the video and realized I was lost in thought and didn't listen to a thing. I literally cant finish this video. This is the 4th time I had to replay it.

  • @ellibrador424
    @ellibrador424 Před 9 měsíci +1

    Anybody else set the speed playback to 0.5 to keep with this guy and understand the video?

    • @ADHDreamy
      @ADHDreamy Před měsícem

      No, but judging how stressed I feel after trying to keep up, I wish I would have!

  • @lovesnhugs
    @lovesnhugs Před 8 měsíci +1

    I love your videos. Do you or could you do a video on NAC supplement
    And also NAC compared to acetylcholine

  • @quietnerdything7176
    @quietnerdything7176 Před 2 lety +6

    Funnily enough, I had to rewatch this twice to actually pay attention to everything

    • @benplayz7694
      @benplayz7694 Před rokem +1

      🤣 I had to watch it several times...because I'm always distracted by the comment section.

    • @ADHDreamy
      @ADHDreamy Před měsícem

      Same here!

  • @pavelsavelev2560
    @pavelsavelev2560 Před 2 lety +1

    great video ! gonna blow up for sure

  • @senseofmindshow
    @senseofmindshow Před 2 lety +39

    Awesome summary! Whenever I hear about the neurological causes of psychiatric conditions, my mind always goes to individual variability. It sometimes seems like neuroscience is trying to find single causes of conditions that may, in reality, be clusters of symptoms that each have different (though sometimes overlapping) causes. My guess is that neuroscience combined with genomics and behavioral genetics will start to show that. Thank you for your content!!
    By the way, I make neuroscience videos as well and I’m wondering if you’d ever be interested in doing an interview on my channel?

    • @neurochallenged
      @neurochallenged  Před 2 lety +7

      Yes, I agree about the origins of psychiatric conditions. There are likely multiple mechanistic pathways that can reach the same cluster of symptoms, and also it's likely that any single pathway can lead to multiple outcomes.
      It's a busy time for me right now since it's mid-semester (I'm a prof) and I'm in the midst of writing a book, but if we can look a little further off into the future I'd be happy to do an interview for your channel. Why don't you reach out to me at neurochallenged@gmail.com.

    • @gnosis8142
      @gnosis8142 Před rokem +2

      No, there's definitely a commonality.

    • @VulpeculaVolo
      @VulpeculaVolo Před 4 měsíci +2

      @@neurochallenged What percentage of the cause is confabulation, medicalization and Munchausen Syndrome? It occurs to me that paying attention can be an intentional and voluntary act. I presume I could intentionally emulate the behaviors and thought patterns of a person with 'ADHD' and generate a similar neurochemical profile. How do you resolve the correlation causation problem? We can easily test whether behaviors can generate chemicals, but it's difficult to reliably test whether chemicals generate behaviors. Why are we using the explanation that is difficult to test and vulnerable to confabulation, when we have one we can easily test that eliminates confabulation from the equation?

  • @ayesha8091
    @ayesha8091 Před 9 měsíci +2

    I'm a med student and suspect I may have ADHD. But I can't seek support yet. Life can be so hard, especially with my grades falling and everyone keeps telling me to 'focus' more when I literally cannot.

    • @aliahalissajensen2590
      @aliahalissajensen2590 Před 8 měsíci

      Why can’t you seek support?

    • @ayesha8091
      @ayesha8091 Před 5 měsíci

      @@aliahalissajensen2590 Mostly due to social stigma. I dont want to be ostracized

  • @MageDawnStar
    @MageDawnStar Před 2 lety +2

    I love that the transcript is in the description

  • @mujinaumemiya3130
    @mujinaumemiya3130 Před rokem +1

    In terms of mapping of neuronal networks as brain structures and the functional networks of the brain, only dopaminergic system is understood as neuronal network for reward system. The rest of the brain functions are yet to be mapped to the structure; people are discussing about functional networks, but it may or may not correctly reflect the brain structures, while the latter is the real. With integrating current research methods, it may be possible to draw the blueprints of the brain of mammals. There is good understanding of nerve circuits of C. Elegans, which is a textbook example.

  • @desiredecove5815
    @desiredecove5815 Před 2 lety +2

    Another great video. Sharing

    • @desiredecove5815
      @desiredecove5815 Před 2 lety

      With Multiple Sclerosis- if our nerves in this area are damaged by lesions- patients can exhibit these symptoms.

  • @rob5393
    @rob5393 Před 2 lety +12

    What is ADHD? Not being able to watch this video in normal speed and set it to x2

    • @VulpeculaVolo
      @VulpeculaVolo Před 4 měsíci

      Are you bragging? I'm confused.

    • @rob5393
      @rob5393 Před 4 měsíci

      @@VulpeculaVolo "not being able to" denotes lack of capability, and that normally isn't a flex. Peace out

    • @VulpeculaVolo
      @VulpeculaVolo Před 4 měsíci

      @@rob5393 I think you can help watching videos at x2 speed since you have to intentionally push the button. Doesn't make you crippled. Peace out doesn't mean I won't respond by the way.

    • @rob5393
      @rob5393 Před 4 měsíci

      @@VulpeculaVolo probably you took it too literally

    • @VulpeculaVolo
      @VulpeculaVolo Před 4 měsíci

      @@rob5393 No I get it. You're proud of your diagnosis because it makes you special and gives you excuses. ADHD is fake bud.

  • @kerstoneshepherds2035
    @kerstoneshepherds2035 Před 2 lety +7

    I got to about 0:22 when i suddenly did the *back to reality head shake* as i said "wait, what??" realizing i had ALREADY zoned out. Oops. LMFAO Going back to finish watching now, then the COVID 19 video next. Post-COVID brain was like taking my usual ADHD and cranking it up from a level 10 to level 100. And the aphasia was horrible, very frustrating, and rather scary.... to know that you KNOW something, but its like totally random bits of data being corrupted or deleted from your harddrive.

  • @zhill2001
    @zhill2001 Před 2 lety +5

    As someone with severe adhd that is in college to be in both pharmacology and neuroscience,After alot of thinking and personal feelings and experiences,i think its both genetic and how you grow up/how its managed throughout puberty.Now my hypothesis is people like me probably have a genetic mutation on Dopamine receptor D2,aswell as D1 and D4.I also believe People with adhd tend to have excess amounts of norepinephrine,dopamine within their synaptic cleft.People with severe adhd may also have tics,coming from rapid dopaminergic influxes.ALSO people with adhd have a higher chance for risk taking and addiction because Of Dopamine fluctuations,this is also due to a mutation in Monoamine Oxidase,allowing more monoamines to be in the blood.Lastly,my recent studies have shown that The striatum & Dorsolateral Prefrontal cortex in people with adhd functions both more effectively and neuroplasticity happens in a quicker manner.I believe the DLPFC is a bigggg target for this.

  • @AB-zq4fw
    @AB-zq4fw Před 2 lety +4

    Here I am singing 80s music and wandering off in thought when my intention was to learn how ADHD works.

  • @madisonla1803
    @madisonla1803 Před 2 lety +1

    Thanks!

  • @huh2852
    @huh2852 Před rokem +1

    I know my ADHD is bad when I get distracted watching this two minute video about ADHD

  • @Sp3ctralI
    @Sp3ctralI Před 2 lety +2

    My personal ADHD:
    jumping a LOT when excited or playing video games
    Needing to be multi tasking
    Stimming
    Sometimes focusing on tasks that involve plenty of movement (drawing, typing, video games, or making music)

    • @janfal4252
      @janfal4252 Před 2 lety

      you sure that’s adhd???? not like, autism or something?

    • @Sp3ctralI
      @Sp3ctralI Před 2 lety

      @@janfal4252 I’ve got more symptoms, and some tend to be possibly for both ADHD and Autism, I probably also have autism, but ADHD is 100% genetic, Autism possibly is a skipping generations type of thing.

  • @Aflay1
    @Aflay1 Před 2 lety +3

    I wouldn't say overestimating short term rewards, so much as valuing short term rewards as more of a necessity.

  • @RealDTSM
    @RealDTSM Před 2 lety +3

    god it feels weird having both ADHD and Autism. definitely makes it harder to pay attention sometimes, though doing hands-on stuff helps i guess. or just learning on my own

    • @ceebee
      @ceebee Před rokem

      That's actually known as AUDHD

  • @ekszentrik
    @ekszentrik Před 2 lety +2

    Me: Take that, default mode network!
    **maximum default mode network suppression beam applied**
    P-Zombie: I am cured.

  • @ineemilieisberg231
    @ineemilieisberg231 Před 2 lety +1

    Funny how I couldnt pay attention to this two minute video and had to watch it 4 times before I registrered what he said

  • @zashuahall8252
    @zashuahall8252 Před 2 lety +2

    This took 6 mins to watch properly.

  • @schneiderdoom2960
    @schneiderdoom2960 Před rokem

    I tried watching it four times but had to start over in the first 30 seconds cause i was zoned out.

  • @Nike-nm8jc
    @Nike-nm8jc Před 2 lety +2

    POV: you're looking for info about your ADHD and are suprised about the amount of "it's theorized" and "it's believed" and "it may" phrases in the video.

    • @Kamexe
      @Kamexe Před 2 lety +1

      Mental health/neuro science is so often just "theorized" based on studies but it's all so not- uniform. Its frustrating lol.

    • @plants_before_people5329
      @plants_before_people5329 Před 2 lety +1

      Almost like there is still a lot we don't know about our brains

    • @VulpeculaVolo
      @VulpeculaVolo Před 4 měsíci

      That's the science on ADHD bud. It's fake.

  • @kaba1996
    @kaba1996 Před 2 lety

    Yes it's exactly me

  • @rafaelribeiro297
    @rafaelribeiro297 Před 2 lety

    Amazing video....btw, do you ship your book to Brazil?

    • @neurochallenged
      @neurochallenged  Před 2 lety

      Hi, my book is sold through major retailers like Amazon, B&N, etc. But I don't control shipping so I'm not sure where exactly they ship.

  • @faithdefeyter9027
    @faithdefeyter9027 Před 2 lety +1

    This guy sounds like one of my professors who studied neuroscience

  • @tarteelmusa7670
    @tarteelmusa7670 Před 2 lety

    Does this channel benefit to the medical student of dependence on them?

  • @yay-cat
    @yay-cat Před rokem +1

    I’ve heard that as ADHD is neurodevelopmental so brains don’t develop in the same way, but that this underdevelopment might be driven by something like insufficient brain energy (like ATP) like a problem with the mitochondria or metabolism of the brain (I think you only get mitochondria from your mom so I have questions considering how heritable the condition is). Also I understand that maybe there’s also some immune or inflammation thing that might be causing problems like cytokines or something. To me it seems that the immune system, the brain/ nervous system, and the metabolic system are maybe 3 of the most complex so I guess that might also be why it’s so tricky to understand what’s going. Also never mind the effects of hormones (like I feel like my menstrual cycle is forever gaslighting me by making my symptoms vary from devastating to kind of manageable and back again)

    • @aliahalissajensen2590
      @aliahalissajensen2590 Před 8 měsíci

      Babies exposed to pesticides also cause a higher risk in getting ADHD. (When pregnant)

  • @Stoogie
    @Stoogie Před 2 lety +1

    A lot of misdiagnoses for general hyper-masculinity in normal male behaviour or on the extreme asperger masculine side, grey areas.

  • @dermuiker
    @dermuiker Před 2 lety +4

    i dont understand what "dopamine is often implicated in adhd" means. does increased adrenaline and dopamine somehow counteract genetics and epigenetics of individual or alter the atypical conectivity in default mode network?

    • @neurochallenged
      @neurochallenged  Před 2 lety +3

      It just means that atypical dopamine transmission is thought to play a role in ADHD. This idea first emerged when it was found that drugs that increase dopamine activity (such as amphetamine) could treat the symptoms of ADHD. For a while it was thus thought that ADHD might be caused by low dopamine levels, but this is now generally considered an oversimplification. Dopamine plays an important role in attention and increasing dopamine levels seems to increase attentive capabilities, but the precise role of dopamine in ADHD is still unclear.

    • @Lazymath007_
      @Lazymath007_ Před 2 lety +1

      @@neurochallenged I have adhd. When I look deep inside myself, I realize it's only 1 issue and that's a lack of dopamine. I constantly feel under-stimulated and a lack of motivation. In fact motivation and attention are highly correlated. If you lack motivation, you won't really focus on anything hence why the default mode network is so active in our brains. Due to a lack of focus, it causes symptoms like forgetfulness and disorganization. Due to a dopamine deficifncy, our brains tend to crave an activity that provides most dopamine in the shortest time possible which causes us to be impatient in every aspect of life causing symptoms like impulsivity, hyperactivity and irritability. A lot of people have considered me intelligent due to my good problem solving skills and the only reason for my underachievement despite my other cognitive abilities really seems to point towards a lack of dopamine which is a lack of motivation which results in me choosing laziness and instant gratifications over hardwork and delayed gratifications. So in short we are just lazy people whose reward systems are not easily impressed. But once something tends to catch our reward system's attention, we not only focus but reach to a state of hyperfocus which refers to extreme focus on every detail . Some may call this as an ADHD superpower. Again this display of addictive behaviour could be explained by us trying to make up for our lack of dopamine, however if channeled in the right path a person with ADHD can be super successful. However I think its better to live with a reward system that's impressed more easily, to live a simple, practical and better life and function like everyone else!

    • @VulpeculaVolo
      @VulpeculaVolo Před 4 měsíci

      @@neurochallenged I'm curious how this can be considered evidence of anything at all. Isn't it true that personality type in general can play a role in neurochemistry? It's subjective whether this is even a problem. You being uninteresting does not mean that I have a mental disorder. The 'hyperfocusing' of ADHD indicates that they most certainly CAN pay attention if they find something interesting. Wouldn't it be better for everyone to attempt to be more interesting rather than chemically neutralizing people who think you're lame? Considering that 'sit still, shut up, and listen to me', is something a narcissist might say to you regardless of any 'behavior' on your part, it occurs to me that ADHD is a particularly convenient tool for gaslighting control freaks. How do we know we're drugging the right person? Isn't it just as likely from the data that the behavior generates the chemistry, and not the other way around? You seem to indicate that the data has become LESS clear from our original assumptions about neurochemistry. Doesn't that WEAKEN the case, which was already subjective and weak in the first place? Why are we still calling this a disorder? Sorry. That last one was a rhetorical question. I know it's for drug sales. BTW: Be careful dishing out those diagnoses. If people with ADHD become the majority, they might decide the slow boring people are the ones with the disorder. We'll call it TDD (Tragically Dull Disease).

  • @kangsankim6992
    @kangsankim6992 Před 2 lety +3

    patient is satisfied with the video...

  • @ozguromak
    @ozguromak Před 9 měsíci +1

    what is the relation between ADHD and breathing incorrectly lets say whilst you are asleep? I heard that if people with ADHD get their breathing fixed adhd goes away! check it out!

  • @Mr.TactiCal
    @Mr.TactiCal Před měsícem

    could you do a video about my life i could use some how to basic film making

  • @jenniferbates2811
    @jenniferbates2811 Před 2 lety +11

    Great video.
    A couple of great books to check out.
    "A Radical Guide For Women With ADHD"
    By. Dr. Sari Solden and Dr.Michelle Frank.
    "You're Brain's Not Broken"
    By. Dr. Tamara Rosier.
    A great CZcams channel is
    " How to ADHD".
    I'm currently going to college for Psychology and Sexual Science with an emphasis in ADHD.
    I myself have ADHD as well.

  • @AmyFerguson
    @AmyFerguson Před rokem

    What you do also changes your brain

  • @ryanbaconsizle9119
    @ryanbaconsizle9119 Před 2 lety +1

    damn this video was pretty good I think, Idk I got distracted 30 seconds in, feels bad LMAO

  • @heromaiker4414
    @heromaiker4414 Před 2 lety

    You should put sound on the intro, I always think my speakers are muted

  • @jdoyle7768
    @jdoyle7768 Před rokem

    Could someone who gets diagnosed with adhd also have CTE?

  • @ometosrs
    @ometosrs Před rokem

    I zoned out during this video too while trying to watch it ahahaha

  • @shitbag.
    @shitbag. Před 2 lety +2

    Would "lumping" Amphetamine(s) and methylphenidate together as phenethylamine(s) make sense.
    I guess I'm asking what a phenethylamine is.

    • @neurochallenged
      @neurochallenged  Před 2 lety +4

      Phenethylamines are a class of compounds that have a characteristic chemical structure and act as stimulants. Methylphenidate and amphetamine both are in that class, so yes they are both phenethylamines.

    • @shitbag.
      @shitbag. Před 2 lety +1

      @@neurochallenged You rock thank you

  • @Blukeylukey
    @Blukeylukey Před 2 lety +1

    literally me

  • @jasminamaric3580
    @jasminamaric3580 Před 2 lety

    Kako dobiti prevod na bosanski

  • @phail_trail
    @phail_trail Před 8 měsíci

    No joke, I got distracted while watching this! 😂

  • @2gr82b4gotn
    @2gr82b4gotn Před 2 lety +2

    As someone who was diagnosed with this in my 30's at first I felt validated, but as I have grown I have realized that there is a stigma associated with something that is a gift.
    IMHO, it is not a disorder. If for some reason you are in a career that it causes you trouble, then you merely picked the wrong career for your mental toolset.
    Would you expect a carpenter to be able to do his job with a plumbers tool kit? I think not.
    I was told in 1995 after a 3 month long study on adults with this condition that out of the 200 or so subjects that I was one of the two that had a "profound" case. Oh, wasn't that special? I was taking 15 mg of Dexedrine twice daily to be normal. Got really tired of that, but I noticed something, and it was not the squirrel outside the window, or the bug flitting around. It was the fact that when I was taking medication to be "normal", I found that my troubleshooting skills were way off. I found that I was taking 3-4 times as long to go through complex diagnoses of problems, so I ditched the spice and the next day I could see clearly the patterns involved in problems again.
    I could finally see how this brain I have, the one with low blood flow to the prefrontal cortex was a gift from God, to allow me to far surpass the normies at my job.
    In fact as I progressed through my career as a Industrial Controls Engineer I began to notice things like after 2 months on the job, I was travelling twice as much as others. They were doing the design work while I was the one going around solving the issues that have been going on for weeks or months. Not only could I solve the problems, I was solving issues that the original equipment manufacturers guys were having issues with. It was fun to walk into a plant at 10 am, and leave at 2:30 with the problem in my rear view mirror.
    Doctors, (Diagnosticians, Neurologists, etc...), Lawyers, and other careers can benefit from this type of brain as well. You ask why is that?? Well then, let me explain.
    You gain knowledge as you learn things, all of this ads up in your brain. As you "fix" problems, all of that is in there... Having a brain that can freewheel in the background and say, here are the twelve issues that we fixed in the past that were similar. Once it notices that it goes through and compares them to what you are facing and eliminates the poor choices, and gives you the best to ponder in your active brain. It also in another part of your brain taking the initial information you had about the problem and as you are going through the troubleshooting process, keeps repeating the going through old issues as the variables change. You are also troubleshooting ahead of the game, because your knowledge is leading your other background task down the paths that are most likely based on what you know and keep finding out about this issue.
    Until, you finally have the "aha" moment.
    This is also why you have learned that if someone says, "I checked that", or "I already did that", or anything similar that you just nod your head and proceed.
    Your reasoning is that if I do not recheck what they checked, I will not see the things that they SHOULD have noticed. Or, they did a poor job of checking.
    Regardless, ( Did you know that until recently irregardless was not really even a real word, but it finally got added to the dictionary a year or two ago).
    Regardless means "without paying attention to the present situation; despite the prevailing circumstances" so would irregardless mean "paying attention to the present situation; due to the prevailing circumstances"?
    oops Back on track
    Regardless of the reason that you do things in a certain way, (Look for the patterns), you will find them, you learn to excel because of and not in spite of this "disorder".
    You are not broken, defective or hindered by your thought processes and the way your brain works unless you believe it to be that way. Learn how to make it work for you and not against you. Oh, I still say the wrong things at the wrong time and get impatient and impulsive at times, but people know that I am ME, and it is acceptable to them.

  • @johnypanta6208
    @johnypanta6208 Před 2 lety +1

    Can you make a video about Introversion / Extroversion? I find this subject very interesting!!!

    • @neurochallenged
      @neurochallenged  Před 2 lety +2

      That is an interesting topic. I'll see if I can work it in at some point in the future.

  • @MohaZeine
    @MohaZeine Před měsícem

    Mm great video Ritalin stopped working on me he is on very long vacation

  • @aldenfriend9625
    @aldenfriend9625 Před rokem

    ADHD: It’s a 2 minute video and I have to watch it ten times

  • @hwernie
    @hwernie Před 2 lety +1

    Yasss

  • @cezbabe
    @cezbabe Před 2 lety +1

    It's too fast for my possible ADHD brain to swallow all at once, ahaha.

  • @TTvpotato-rp2js
    @TTvpotato-rp2js Před 2 lety

    i have adhd dosent people with adhd are smarter when they want to be im really good at history scince i like it i learn alot abt it even not in school

  • @Xyxle410
    @Xyxle410 Před 2 lety

    Me am have this

  • @globalrxmed
    @globalrxmed Před 2 lety +1

    watson

  • @val2erW_g
    @val2erW_g Před rokem

    I have always been told I have adhd by doctors ect: but I think there's something else like autisim

    • @ceebee
      @ceebee Před rokem

      There's a lot of comorbidity between ADHD and ASD. It's entirely possible to have both, which is sometimes referred to as AUDHD. In fact, I remember reading somewhere that there was a proposal to merge ADHD into ASD as a subtype in the next DSM spec.

  • @oh5793
    @oh5793 Před rokem

    Having this and ocd at the same time makes me want to rip my brain apart 😔

  • @Kamexe
    @Kamexe Před 2 lety +1

    It also shows itself differently between sexes males are often more physically hyperactive as opposed to females where it exhibits more in a mental form.
    this makes sense between my adhd, asd, ocd, and other shit. This feels so correct lol. It also to an extent feels like it should be categorized as a learning disability cause fuck my social skills and school are impacted and still are. I wonder if it contributes to my short term memory. I wasn't diagnosed until highschool and for girls since it exhibits differently. That's why the diagnosis was so late.

    • @singingnymph
      @singingnymph Před rokem +2

      The thing about the sexes isn't necessarily true. The erroneous focus on hyperactivity as the stereotype makes it seem that way, though. Regardless of sex, many who have the less hyper, more inattentive type get overlooked or misdiagnosed, because they're basically flying under the radar & falling through the cracks. The focus on the H part of ADHD did a huge disservice to so many people. Kids who needed the support didn't get it, & some kids who are just naturally active (when maybe all they needed was sports, dance, gymnastics, etc) got an erroneous mental health diagnosis.

  • @jasonfortress9027
    @jasonfortress9027 Před 2 lety +1

    Me rewinding because I'm looking at the comments

  • @ceebee
    @ceebee Před rokem +1

    The description at the start of the video is describing ADHD the same way that the people who came up with the name. Which is by focusing on the aspect of it that everyone else finds annoying. ADHD is so much more than "difficulties with attention". So much so, that it's often referred to as the ADHD iceberg, because the list of symptoms is extensive with "attention" issues being only just the tip of the iceberg that's most visible, with the greater portion of symptoms being invisible and below the surface (both literally and figuratively).
    The rest of the video is on point, but that initial description is trash and reinforces stereotypes and misconceptions.

  • @bernadettehoward2561
    @bernadettehoward2561 Před rokem

    I can’t even pay attention to this I have to keep restarting or the intake of this information my brain is neurodivergent I mean I have a learning disability

  • @ThePitchblue
    @ThePitchblue Před 2 lety +2

    how do you call the opposite of adhd or even add? cause I have it.

    • @jenniferbates2811
      @jenniferbates2811 Před 2 lety +1

      It's only ADHD now, it's been reclassified. Go to a Psychiatrist and find out what you have.

    • @singingnymph
      @singingnymph Před rokem

      They unfortunately rolled ADD & ADHD into one, & people zoomed in on the H, thinking it meant physical hyperactivity & not the brain. So you probably do have it, but's it's not necessarily the opposite. There are people who are just naturally active who have ADHD, & people who are more the daydream type with ADHD.

    • @ThePitchblue
      @ThePitchblue Před rokem +1

      @@singingnymph I actually have OCD, genius.

    • @singingnymph
      @singingnymph Před rokem

      @@ThePitchblue That's not uncommon with either one. ❤️ People with a tendency to over think, be it those with OCD, ADHD, Autism , etc, are often quite intelligent. More so than people give them credit for.

  • @RemmyRoo
    @RemmyRoo Před 5 měsíci

    Thank god it’s only 2 minutes I wouldn’t have been able to focus

  • @LORITOTH29
    @LORITOTH29 Před rokem

    Lmfao- me over here with ADHD… anyone else have to watch this vid 3x to really HEAR and understand what he was saying 😂. Not that he doesnt explain it right- because even reading a book i gotta re-read everything multiple times to actually absorb it! Lol

  • @gratefulkm
    @gratefulkm Před rokem

    Dopamine is Worshipped on the channel
    They prostrate themselves in front of it

  • @andorifjohn
    @andorifjohn Před rokem

    There's still no good video that I can find that goes through and explains the evidence behind adhd and related conditions.

  • @iranjackheelson
    @iranjackheelson Před 2 lety +4

    0:14 "ADHD involves strong genetic influences" Can you say which paper backs up this statement and how strong it's shown to be?

    • @neurochallenged
      @neurochallenged  Před 2 lety +9

      All three of the references I've included in the video information emphasize the importance of genetic factors in ADHD and back up that statement in the video. Here is some text from one of those papers (Gallo & Posner, 2016) that includes a heritability estimate: "ADHD is a highly heritable disorder. Studies of twins, families, and adoptive children or siblings have estimated a heritability ranging from 60% to 90%." Full paper is here: www.ncbi.nlm.nih.gov/pmc/articles/PMC4893880/

    • @jenniferbates2811
      @jenniferbates2811 Před 2 lety +2

      Yes! ADHD is hereditary, but for most parents, they see it as their
      " normal" so when their kids get diagnosed they don't understand the how or why.
      Also this is how some people find out that their biological parents are not really their parents. This happened to my best friend.
      As an example:
      I'm 45(F) my grandfather had ADHD, he was a math and history genius. My dad was born in a different country had ADHD, my mom born in the USA, me and all 3 of my kids have ADHD as well. They are 22,23,24 now.
      Some people for reference:
      *Dr. Sari Solden, *Dr. Michelle Frank,
      * Dr. Tamara Rosier. They've written great books and have amazing research.
      Also on CZcams:
      "How to ADHD" great channel.

  • @nisargbhatt4967
    @nisargbhatt4967 Před rokem

    good figures but this 2 minute explanation left me more confused than before

  • @pasalasaga
    @pasalasaga Před 2 lety +1

    I didn't get It.

  • @sizzle9682
    @sizzle9682 Před 4 měsíci

    That shouldn’t be it’s name bro it’s not a disorder. it’s jst everyones brain has different electrical signals cause of how different groups evolved so ofc some kids brain signals will be telling them to run around or do other stuff making it hard to focus. But commonly in these kids they will understand what’s going on if they are interested and can actually be a lot smarter then kids without adhd. Like I said tho to even categorize different ways brains work is really not smart, cause now the kids who are diagnosed with thinking differently will be ashamed and discouraged to put in any effort and making them feel bad abt themselves will prohibit them from becoming as smart as they could be. There’s a proper way to encourage a child and this is not it.

  • @hanskraut2018
    @hanskraut2018 Před 2 lety

    @neuroscientifically challenged
    Russel Barkley PhD most cited adhd scholar in the world has some nice presentations where sources of brain regions associated with adhd across meta reviews/metaanalysis of most (not sure on what proportion) mri usw scanning study’s where analyzed.
    You might be interested in the citations for a future update on this video. :) Thanks for the vids.

    • @jenniferbates2811
      @jenniferbates2811 Před 2 lety +1

      Some others you may be interested in:
      Dr. Sari Solden, Dr. Michelle Frank and Dr. Tamara Rosier. Have amazing books and tons of research.

  • @panish2472
    @panish2472 Před 2 lety +2

    So what makes ADHD brains more hyperactive?

    • @atomicgps7488
      @atomicgps7488 Před 2 lety +1

      H

    • @VulpeculaVolo
      @VulpeculaVolo Před 4 měsíci

      They don't know. Kinda makes you wonder why we're still calling it a disorder.

  • @andrew-wait
    @andrew-wait Před 4 měsíci

    I got distracted and had to start from the beginning.

  • @NadDew
    @NadDew Před 2 lety

    huh?
    I couldn't follow.... 😟

  • @gudarzfindi8026
    @gudarzfindi8026 Před 2 lety +2

    First to comment 😎 admin they say you like comments 🤨

  • @cbizzle4299
    @cbizzle4299 Před rokem

    Wait.... which brain is normal and which is ADHD....

  • @Pengalen
    @Pengalen Před 2 lety

    I'm not sure that really told me anything. It said "there are differences here and here" but didn't really say anything about what those differences are. Maybe this format is just too short for that.

  • @invader_ren5974
    @invader_ren5974 Před 2 lety +1

    Can you simplify what you just said? 😵

  • @loska9407
    @loska9407 Před 2 lety +1

    i love the video
    i hate the hand

  • @alexandersantos7476
    @alexandersantos7476 Před rokem

    All i hurd was adhd

  • @hanskraut2018
    @hanskraut2018 Před 2 lety

    Too much focus on attention. You can hear the underlying assumption of the textbooks: "Happy person that makes the wrong decition because does not know information X. Very happy shortterm but then in trubble because did not do the work." Its better to think of attention in that sense as feeling good/motivated and reducing pain and bad feelings. Also intense boredom and lack of interesst in anything will free up the attention that then somethimes wanders to a bird in the window but that is also boring. Some people talk of hyperfocus what they mean is they finally focus on something wihle ignoring 10 other relevant things and because they did not do it in a while it feels hyper. (many do not report this) The fidgeting is assumed to come from high energy, in reality at lest in my experience its because you feel bad and you move because you try to do ANYTHING to not feel bad. Adhd people on average are overweight and sedative not sportler. Many people call themselfs ADD not adhd generally that means they are less severe or have S.C.T. witch is not adhd. SCT can be comorbid with adhd. SCT is still in research for the last 2 decades and not so perfectly and completely researched that it is as definitive as other disorders in the DSM-5 or in the worse (at least for adhd) ICD-10 so take it with a minimal grain of salt. Iq and other great or bad abilitys do exist in people with adhd, like abilitys exist in people with cancer. If your adhd is an advantague for you then it is not adhd because adhd diagnosis if done competently requires general impairment in all life activitys due to adhd. Adhd people generally think they are misunderstood and relly smart and creative or that adhd does not exist and its big evil pharma and then they trust there drug dealer and THC-Oil. Smart: Sure generally ur capable to do way more but u are not so u got potential if u can treat it perfectly. Creative: If someone is impaired they have to get creative and even if they dont the fact that they do everything different because they are fucked makes them creative, adhd people on all messurable metrics suck so it continues to be reports that cant be verified like flat earth and all the other wrong stuff people strongly believe and defent ferociously.
    People often say they can focus on video games great but not schoolwork. Generally video games are better because they require less happyness/motivation/brains but normal people are even better. Normal people > adhd people when it comes to video games. Sure some annoying adhd people say they are good but again if you spend 10 years and ur better than a person that spend 1 year playing a game, or ur talented in some way since again adhd is not all you are.
    In conclusion: Happy, distracted, relaxed, energetic person = wrong. Unhappy, no drive, bad feelings, fidgety person, brainfog, bad intuition = better But how do you know ur less happy when its all u every experienced, well if u take meds and they are perfectly dosed (rare to find thats why evil pharma meds dont work so prevalent) then u get to know how awesome the other people feel and they are just selfish complaining assholes that dont get as overly exited as you about random things that's why you thought ur the same. If ur happyer u dont need to talk and be interessted in random things because good feelings are plenty. Then u also do many hard things and realize people are not more tuff and "take the pain" they have less pain or more drive and happy to make the pain bearable
    Its 2022 look at history scientific revolution since ~100 years but still knowledge is revised periodically (even if way less often than the ~liniar increase in errors when going back in time). Bipolar was once not differentiated from depression. It wont stop here if this very reliable trend that we are not all knowing kontinues. But the information today is way more reliable then when going back in time. People are generally different when they have no money or a knife to there throat also take this into account when looking at history.