Humoral Immunity | The B-Lymphocytes | Immunology | Physiology
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- čas přidán 18. 12. 2021
- Humoral Immunity | B-Cell Immunity | The B-Lymphocytes | Immunology | Physiology.
The B-lymphocytes start as naive B-cells, then they recognize the antigen and mature. Next, they will change into Memory B-cells, and Plasma cells. Plasma cells secrete antibodies (immunoglobulins or gammaglobulins). These antibodies are IgM, IgG, IgE, IgA, and IgD. Each immunoglobulin has 2 heavy chains and 2 light chains..
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![Cell-Mediated (Cellular) Immunity [aka T-cell immunity] - Physiology & Immunology](http://i.ytimg.com/vi/M6XI1DZIdLk/mqdefault.jpg)
![Cell-Mediated (Cellular) Immunity [aka T-cell immunity] - Physiology & Immunology](/img/tr.png)
I mean why the heck our professors are not explaining things that simple as you
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Unfortunately many no longer know how to teach and just read slides to students and get upset when questions are asked.
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enjoyed and thank you for the idea of waiter being the APC and his plate being the antigen
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Thanks! Also the variable domains are just the outer domains of the Fab fragments. A single Fab fragment has four domains, two of which bind the antigen (heavy chain variable and light chain variable, VH and VL on this diagram) and two of which don't participate in binding (heavy chain constant 1 and light chain constant, CH and CL on this diagram).
incredible illustration, I absolutely like the ways u explain things... u made complicated things become ez to understand
Happy to hear that!
Perfect and enjoyable demonstration Doc; keep it up
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wow this video is so helpful I have spent hours organizing the cells on what they do and what systems we use them in and I could of just watched this video LOL
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this is just what i wanted.can you please make the fonts a bit bigger or typed plz? It would be great for almost blind people like me🙂
As as you said in ur lec Antigen Presenting Cells present Antigen via MHCs to either B Lymphocytes or T lymphocytes but later on we study APCs have MCH II molecules which can interact with Only CD4+ or T helper cells only.
Do APCs also have MHC I as they are nucleated too?
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Sir in your slide 'The Antibody in action' you showed a macrophage with Antibody attached to it No MHC no lymphocytes involvement?
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thank you so much for this video, i can finally understand how the immunity system works, I really appreciate these videos. The art and stories are so entertaining and very educational
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I LOOOOOVE this video! I have an exam in a few days and I am confused about one thing in here. Can someone please clarify? If the APC can be a B lymphocyte, then would he only ever present to a T lymphocyte? Otherwise, all non B cells that are APC, present to a B cell?
B cells typically present antigens to T cells.
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Best explanation
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Amazing explanation as always. Thank you so much Medicosis!!
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What lung disease affect and damaged both of lungs? Real truth
Sir what about dendritic cells... is this a type of antigen presenting cell and can they help in activation of B lymphocytes????
I m glad to get your reply sir thanks..🙏
Yes!
Dendritic cells are equivalent to Langerhans cells in the skin!
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you made a mistake!
actually only T cells receive antigens form the APCs.
the antigens presented to the B cells flow autonomously trough lymphatic vessels from the site of infection up to cortical region of lymph nodes where they can meet B cells.
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Exactly those woke professors, stand there for 2 hours and mumble a bunch of nothing to understand. 10000% Thanks