Proteomics

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Proteomics is the large-scale study of proteins, particularly their structures and functions.[1][2] Proteins are vital parts of living organisms, as they are the main components of the physiological metabolic pathways of cells. The term proteomics was first coined in 1997[3] to make an analogy with genomics, the study of the genome. The word proteome is a blend of protein and genome, and was coined by Marc Wilkins in 1994 while working on the concept as a PhD student.[4][5]
The proteome is the entire set of proteins,[4] produced or modified by an organism or system. This varies with time and distinct requirements, or stresses, that a cell or organism undergoes. Proteomics is an interdisciplinary domain formed on the basis of the research and development of the Human Genome Project;[citation needed] it is also emerging scientific research and exploration of proteomes from the overall level of intracellular protein composition, structure, and its own unique activity patterns. It is an important component of functional genomics.
While proteomics generally refers to the large-scale experimental analysis of proteins, it is often specifically used for protein purification and mass spectrometry.

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[@NareshKumar-ye3pr]

Great 👍. Good video. But wanna tò know can we use use this technology for forensic science in place of DNA

[@sumitaganguly2081]

Excellent video and very clearly explained!

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[@salvadorhirth1641]

Hi, thanks for sharing knowledge; please let me know if you know about the possibility to use fusion peptides with liposomes to deliver restriction enzymes into cells. I realized that a palindromic sequence like AAGCUU, has a limited possibility of mutations, therefore, about 27 different restriction enzymes should be able to cleave any given six bases palindromic sequence of viruses; think about the importance of a new approach to fight viral infections, borrowing restriction enzymes from bacteria. I hope that fusion peptides can make restriction enzymes penetrate the cytoplasm of cells, in order to cut viral RNA. This approach should not be safe to fight DNA viruses, because if the restriction enzyme able to cleave palindromic sequence get into the nucleus, it would damage non methylated cell DNA.

[@salvadorhirth1641]

I would like to know if there is any controlled frameshift mutation that makes possible for one gene to have two layers of information, so that two complete functional proteins can be encoded by the gene and by the resulting frameshift mutation, please let me know if you have one example. Thanks!

[@user-hp4pk2pd9i]

thank you for sharing ur knowledge wit us. can u send the reference books on this topic.

[@oiawra]

thank you so much! this help me understand what proteomics is. thank you

[@shomusbiologyofficial]

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[@Artscraft13]

Thnk u ❤❤ nice explanation 😊😊everything is clear now about protiomics......

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[@manishavibhute8466]

your teaching explanation method is really very nice sir..

[@globalwit]

thankyou sir the lecture is really helpful .

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Thank you very much Mr. Shomu. I've subscribed

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[@melvingeorge2008]

Thank you Shomu Sir!

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Thank You, very helpfull and enjoyable

[@basavarajkc3717]

I am always gratitude to you sir

[@shomusbiologyofficial]

Thank you

[@kritikabandge612]

I think the pyramid diagram should be inverted as per the number of bases less then amino acids and then metabolites in max. no. and diversity also increase .

[@WorldCollections]

Thank you! Although, what non of these proteomic videos clarify really well is how many simultaneous proteins can be analyzed by MS. I suppose that you can only pick one or two from the 2D gel separation, but not really throw at the MS a complete mix of proteins to get relative abundances?

[@taniabatool4451]

You have always helped me

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[@biology109]

Sir what is the expected average of getting a parasite proteomics done.....any hints plzzzzz

[@SumanMinj007]

Sir... Your way of teaching is very well, But many Hindi medium students do not understand.. So please teach hindi english mix...
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[@shomusbiologyofficial]

I have 47% viewers from outside of India.

[@GoldiJ]

this is good and awesome.......
thank you very much ........

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[@sarmilapanigrahi7617]

Hello sir can u do a videos on bioinformatics and pharmacogenetics..I need to understand but it's little bit different to find...

[@kaviyamehandiarts1987]

Sir! please make a video on metabolic labelling.

[@JordanOshiro]

Thanks, that was helpful! Good explanation!

[@lohoqalam2899]

Sir kindly give lecture on SILAC technique

[@sudalainitinmuthu238]

Can you explain the scope for molecular medicinez??

[@logapriyars1946]

Can you mention the references from which you got these infos

[@nishimishra6361]

Sir if u have Ppt on this topic .. application of microbial proteomes please share with me

[@GHOOMANTUBETE]

you are the best

[@shomusbiologyofficial]

Thank you

[@mehakmunjal2300]

Very helpful, Thanks a ton.

[@nnminhanh]

Thank you

[@Kyrani99]

Great video and uptodate information. Good on you Shomu.

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You're welcome

[@harishs2181]

I'm msc Chemistry I want learn bioanalytical which books I read?

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Thank you

[@pragyasharma7986]

thanks shomu

[@josephfolajimi9646]

wish there were subtitles

[@shreyaj1227]

Soon 800 K followers

[@shomusbiologyofficial]

Thank you

[@hamsalekha38]

sir.can i have the references for this session.

[@mozafarahmed6041]

again, love you !

[@rashamoustafa427]

Great🎉🎉🎉

[@shomusbiologyofficial]

Thank you

[@madwomanization]

Hi do you have any videos on Transcriptomics

[@shomusbiologyofficial]

Not now but I will be doing it soon.

[@parikshitsalam9331]

do u have video related to PROTEIN PROFILING TECHNOLOGY

[@ankushkalish1809]

Proteomics changes...

[@bsc2microbio276]

thank youuso much....

[@swetasagarikaamanta6218]

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[@stephenprice3357]

I wish this video had subtitles bc this guy sounds like apooh from the Simpsons

[@akshayasasi7091]

6.27

[@Ikigaizoologist]

Not upto the mark and as expected 😢