Bland Altman Plot - Neatly Explained: Systematic Error [Bias], How to do Bland Altman plot
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- čas přidán 16. 07. 2024
- This video explains about Bland Altman Plot : Detailed explanation on Systematic Error [Bias], steps for constructing Bland Altman plot and How to do Bland Altman plot.
Bland Altman analysis is a commonly used analysis method in biomedical research.
This method is used to study the agreement between two measurements that are in continuous scale.
This method was introduced by J M Bland and D G Altman in the year 1983.
Bias is evaluated when:
Introducing new methods or instruments
To check consistency between parallel instruments
To check performance of new lot of reagents
To check changes in performance over time
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Thank you!
Thanks so so much
In case of checking changes in the performance over time do you mean with same method or technique... I do repeated measure before and after 2 different medications management can I use bland altman analysis to prove the changes are not subjected to bias or systematic errors and these changes occurred because the effect of 2 different management?
regards in advance
Hey! What if your input-data contains only mean values ( plus the upper limitation and the lower tolerance). Is it then possible to use the Bland Altman for method comparison?
thanks for the great explanation. but how to change the 95% agreement difference to percentage?
What do you mean? Those lines are the limits within which 95% of sample pairs should be. Do you mean you want the lines to instead mark +-X% of the difference? Just draw the lines at +-X%. If you have relative units on the Y-axis, they'll be horizontal lines, but if you want absolute units they're obviously going to have to be two lines diverging away from the mean in direct proportion to the the average.
For the boundaries you are just using 1.96 X standard deviation of the difference, this equal to a 95% probability assuming a gaussian distribution. Check the gaussian probability function
hi friend, may I know if you had any reference articles for this video? It would help a a lot
You can read some of the original papers Bland and Altman wrote (pubmed.ncbi.nlm.nih.gov/10501650/) or read a more recent review of it from 2015 here (www.biochemia-medica.com/en/journal/25/2/10.11613/BM.2015.015), these are the ones im citing in my dissertation
The data out side the LOA how could you explained it