The Acid-Base Disruption Hypothesis for Long Covid | With Vicky Van der Togt and Jeremy Rossman
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- čas přidán 25. 07. 2024
- Today I’m talking to Vicky van der Togt and Dr Jeremy Rossman about why an acid-base imbalance might be the missing link to understanding what’s causing Long Covid, as per their recently published hypothesis.
They explain how it fits into the well established pathophysiology including inflammation, poor oxygen perfusion and abnormal clotting, as well as causing the much suspected doom loop which the body finds so hard to break out of. It could also explain all sorts of perplexing symptoms, such as muscle weakness, post exertional symptom exacerbation and that soul crushing fatigue.
Resources:
The paper:
www.frontiersin.org/articles/...
FAQ:
researchaidnetworks.org/faq/
Lay summary:
researchaidnetworks.org/hypot...
Audio version lay summary:
• Hypothesis summary - a...
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Before I caught Covid in March 2020 I was a filmmaker. I’m not well enough to go back to work yet (shoot days are brutal), but I’ve decided to indulge my passion by breaking down the hottest recent films and TV shows (from an insider’s perspective with 20 years in the industry) to describe exactly how they work. Sound interesting? Then subscribe to my second channel! (@thescriptflip )
Here are some links:
5 Reasons Why Top Gun Maverick Crushes the Original | Film Director Breaks it Down:
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The Long Covid Handbook (Feb 2023) by Gez Medinger & Professor Danny Altmann (and published by Penguin Books) is now available in paperback, ebook and audiobook. A singular resource that brings together everything patients, clinicians and academics have learnt about the condition to date, as well as lessons from sufferers and researchers of ME/CFS and other chronic conditions. It offers world leading expert advice on understanding, managing and treating Long Covid. It is available from the following links.
US: a.co/d/0gvkJCU
UK: amzn.eu/d/9KjurGb - Věda a technologie
It's been a rollercoaster ride downhill since Feb '20 for me. I love this channel because Gez stays on top of it.
Hi, where would you say your recovery is at today? 50%, 70%, 90% or fully recovered? Thx
Same for me. Rollercoaster but all in all, mainly downhill. I dont know how long I can last.
@@stephangauthier911 same here
Exactly!
A seemingly never ending rollercoaster. Just as one thinks there may be an improvement, one slips right down an invisible slide; completely washed out again and start all over once more!
Gez, truly appreciate your videos and everything you and your fellow interviewers are doing on the Post Viral work. It’s not only interesting but fascinating (when I’m not too tired to understand! lol)
Take care everyone and best wishes to all.
International EU covid summit 2023 May 2023 vaccines discussed czcams.com/video/bFLPWWCAHfQ/video.html
Bwahahaha "It sure as hell isn't deconditioning" - until we become de-conditioned thanks to it. And obese, which they also blames. And anxiety. Because who doesn't get a tad upset when the can't breathe after walking three feet. So happy to hear more answers instead of ignorant practitioners who dismiss us
Which country. In the Czech Republic ignor Long Covid.... We are all crazy 🤪🤪🙈
I was told by my former primary, when I had severe covaids in march 2020, after a 22 pound weight loss (not obese) in 2 weeks, and severe, that I was "debilitated" and as soon as I was negative (4 months later), I was put into PT....it was AWFUL. I had no oxygen or energy to do it - I did it any way and shouldn't but yup! Iso much gaslighting we needed to be in a Burn Unit! You now they needed to be and stay ignorant, to get their incentives to make it look like we needed a a shot to save us...
@@Jennifer-gr7hn I'm sorry you went through that, but it's not going to help anything by promoting additional ignorance
Again, this might be in the chain, the cascade of things that is happening as low oxygen and high lactic is in response to sympathetic overactivity. That's why Wim Hof method is suggested.
Working our way slowly to the top. That would explain why I stop breathing sometimes, especially at night.
Meanwhile, my life is hell. Every part of my body is imbalanced and I have a myriad of symptoms I can't count anymore. I've had infections but for me, the jab made it kick in turbo mode.
Shout out to all the long haulers.
This is exactly what my husband is going through...after his jabs...then getting c19 infections.
I recognise stopping breathing at night and sometimes during the day. Waking up in total panic or feeling scared why my system didn’t want to breath automatically. But still don’t understand it why it would happen. Hope to learn something here…🙏🏼
I'm sorry to hear you got the shot :( I'm so ptsd with how they handled me (or not) with the severe infection in march 2020 that all trust was 'shot' for me but even that, as a nurse, I saw too much. I agree, with the apnea, the sympathetic, etc. I've done so many things but the best have been anything that has to do with oxygen, ozone, etc. I'm doing acupunture now too which is helpful. Also methhylene blue, NAD+ etc. What a trip. Totally relate with the cessation of breathing and it's scary because you don't even feel like you're running out of 02!
Box breathing is suppose to reset the CO2 brain sensitivity. This way the breathing van normalise. Not sure if it s working but I started with 3-3-3-3 and now on 3.5-3.5-3.5-3.5 and working my way up to 6-6-6-6 sec. Hoping to reset my brain in 8 weeks (according to my breathing coach)
@@melanievesters5473 sometimes my resp is as low as 6 per minute. My lungs just go into freeze mode and I can't breathe and then I lay down and I can breathe again
The NHS Long Covid clinic I was sent to in 2021 referred me to a breathing therapist who told me then that all my symptoms could be explained by excess acid. The breathing therapy was a huge help by the way.
Breathing exercises, hyperbaric, aerobic activities...what kind of therapy?
Could you tell us more about what type of breathing exercises you are doing?
@@stephangauthier911 I was seeing them for over a year.
I think part of my problem was that during the original illness I had changed how I breathe several times due to the issues I was having with my lungs.
The therapy began with exercises to clear the nose and making sure I breathed through the nose. Then there were things to do to train me to use the diaphragm and then the stage after that was exercises to control the timing of my breathing (and to make sure my breaths weren't too shallow). Exercises mostly involved breathing, controlling the positioning, some posture, and some timing and holding your breath. Repetition through the course of each day.
Obviously I would suggest that the exercises I was given were specific to the changes I'd made to my breathing patterns and that if breathing is part of the problems others are having what they need to do will depend on exactly how they are breathing now rather than some generic therapy as a one size fits all.
It was a big help though. I wouldn't say I'm 100% but compared to where I was for over a year up to about september '21 I'm probably more than 95% better. By Sept/Oct that year I was about 75% better and I had a steady improvement and as my physical condition improved from being able to exercise (as well as contiunued breathing therapy) it took me a little under another year to get to the condition I've been in for the last 8-10 months.
I also had breathing physiotherapy that helped me. She also said the same thing about incorrect carbon dioxide/oxygen balance in blood causing ph to be off
But is the acid/base shift a cause or a sign?
Lactic acidosis could be caused by decreased tissue oxygenation, thus is a sign rather than a cause.
Fascinating. I've had long COVID since Delta in Sept. 2021. I noticed my food and water cravings changed over time, too. I eat a LOT more vegetables and fruits now, especially potatoes and bananas and drink water all day - two gallons. Slowly recovering myself, but still short of breath and lacking motivation in general. ANA was raised as late as Nov. 2022 and I'm pretty sure I've had multiple TIAs (hospital confirmed D-Dimer raised at least once). In all, I am SO GRATEFUL for the research posted online and available to all. God bless you all!!!
SAME! potatoes help me sleep thru too! and grapefruit craving vit c seems to calm my inflamation...and covid tinnitus..best luk recovering...living w this sht
I started trying this the day Vicky posted on twitter, because when I looked at her PRAL list, I realized my low histamine foods were highly acidic. I started feeling much better within a week. I have pushed the diet to see what is possible, and if I eat without concern for acidity, some long covid symptoms (chest pressure) return. Using PH strips to test alkaline/acid and acid was highest when I ate without considering acidity. I'm back eating mostly fruits and veggies for every meal with about a third acidic foods (bread, pasta etc) and feeling very good. Stretching, water, electrolytes, and other listed recommendations of course. Many thanks!
Great to hear this Michelle!
Happy you are feeling better Michelle. Do you happen to have the PRAL list?
😅😅
There are also studies that suggest that covid may trigger prediabetes and diabetes.
Acid theory fits too.
I had cut carbs to 120 and calories to 1500 a day. Salads and protein.
Feel better and can now exercise.
I also found a low histamine diet to help me the most with the long Covid symptoms that lingered beyond 8-10 months. However, I will now pay attention to acidity as well. I find that I have to eat around 75-80% low histamine diet to feel good. Also, I am now prediabetic according to my doctor and I totally cannot drink alcohol anymore (maybe 1 glass with a BIG meal) because my body cannot regulate the sugar. (I'm responding to Metal) Covid definitely did something to my body's ability to handle sugar. I had a glass of wine every night for the past 35 years (I'm 57) and cannot any longer. I cannot eat sweets either - they make me feel terrible.
We will be patiently awaiting Part 2. Thank you for making this information available. Blessings to you, all!
I have done aerobic exercise testing on multiple long COVID patients who were previously fit police officers and have seen early onset anaerobic metabolism start within 1-2 minutes that completely fits into the anaerobic lactate production post exertion causing fatigue
Yes and that’s the same short time it takes for an ME/CFS patient to go into an anaerobic state.
Swollen epithelium in arteriols and capillaries, combined with micro clots, cause hypoxia, mitochondrial loss of efficiency and damage, and then lactic acid buildup, etc. Then more damage is done, causing more inflamation, etc. Microclots are real.
How are you doing Gez ? I’m sure I speak for many people when I say we’ve missed seeing you regularly!
Thanks Laura! Doing ok but still work to do :)
Hi Gez. Nice to see you again! You are looking well...I hope you are feeling well, too😊 As always, thank you for all that you do. I find this very interesting and am looking forward to part 2. Sending love from Canada ❤
Thank you Kathy!
So lovely to have you back on our screens Gez 👏👏👏 Fascinating podcast - I'm looking forward to part 2 👏👏👏
Thank you Dee!
...And so one-by-one as they caught Long Covid themselves the drive to find solutions became a necessity rather than an 'interesting topic of study'.
And they no longer think it is in your head.
What I find, as a severe infected high viral load from march2020 nurse on frontlines, had stroke during my covid, went right into longhaul, no breaks, many dark thoughts, HORRID nightmare, no medial help, much abandonment, in ptsd counseling for it all and whenever the worst of the symptoms become intensified again, I start going into that time....and what I find it, it's amazing how good they look and sound for being a longhauler. I know eevery one is different but man, I'm jealous...not a word out of place, never lose their train of thought, no concentration issues, no dyslexia. Guess I was beat up pretty bad...
Can you please post part 2 right away. My Mom is very very ill and I’m looking for a break through. This may be the answer for her. Please don’t hold off the information for personal gain. You have been a blessing to us in keeping her going. Thank you for all you are doing.
Prayers your mom recovers soon!!! ❤
@@mindymontez9013 thank you.
It’s not ready to go up yet - will be in a couple of days
@@RUNDMC1 thank you so much for what you are doing. It gives us all hope.
"Personal gain?" Patience please on behalf of the caring team. Most of us here are suffering greatly, and/or helping those who are. Prayers and offerings.
Good to see you again, Gez. These two were so interesting and I wish them all the success in getting the funding they need. This virus is so confounding. I hope we can give people some relief while we're learning, but the journey to understand this virus is fascinating! Take care, Gez!
Thank you Erika!
I think you guys are definitely on to something. I am fine UNTIL I do a weightlifting workout where I have a lactic acid buildup in my system. Almost immediately after the workout I get nauseous, I have difficulty breathing and extreme exhaustion. It takes about a week or two to recover. As soon as I recover I try again and it happens all over again. I would be a perfect person to study because I can repeat the process every time I workout.
yeh workouts are killing me
Swimming a few lengths across a pool and doing pool yoga is all I can manage. It's not okay to feel worse after exercise. I had to give up teaching yoga when I got infected and any exertion causes pain. 😢
After two weeks of Cross Fit I fell back into symptoms again. Nauseous, breathing and exhaustion issues, taking weeks to recover, and then developed PMR.
@@nomebear what is PMR?
Its Dysautonomia/ME/CFS. Follow a dysautonomia recovery protocol. This channel is worthless. Stop working out for a while, or reduce the intensity by a lot. You have to ease back into very slowly. Your body needs to re-adjust.
This is interesting. I pray every day we get answers and treatment 🙏🙏🙏 I know I'll get my prayers answered
In the meantime, don't just pray and wait! ACT! Do anything and everything you can (not at once). HBOT, EBOO, breathe work, manage, lymphatic draining, etc. Thing is.....every one has polar opinions and they all sound great.
Thank you for all of the work you do, Gez.
Good to have you back Gez, your insightful posts have been missed. Sadly the more I hear about long covid the more I'm convinced the illness is ME/CFS just under another name. I picked up a respiratory infection on a long flight in 2011 and have been in a 'long covid' state ever since hence knowing a thing or two about being constantly exhausted. The signature symptoms of the two illnesses mirror each one another so perfectly it's obvious this is one and the same thing, so, if I may be allowed, would suggest these kind folks delve into what has already been researched under the title of ME/CFS as they may well get a jump on results. Huge thx to all putting effort into solving this damned life destroying riddle.
It seems like the dysautonomia I've suffered from for decades. Lot of similar conditions going by different names.
It got so much worse after two bouts of covid. One good that might come from this horrific pandemic is finally validating those of us told it was all in our heads. Finally having something that brought to researchers' attention, the huge number of people suffering with these life-destroying symptoms
I talk about ME/CFS extensively in the book - the two conditions certainly share a lot of pathophysiology. I’ve also made a couple of films on this channel directly addressing what we can learn from ME/CFS research.
the other thing is, Epstein Barr is very common in ME/CFS,, something like 87% of me/cfs sufferers have antibodies for EBV-- (coincidence lol) -- Annnnd-- Covid can *maybe* re-trigger EBV -- so,, EBV, the gift that keeps giving
There's a subset of LC on twitter who absolutely hate the MECFS community and are trying their best to discredit anyone who suggests some LC could be MECFS. I don't think all LC Is MECFS, but there seems to be about 40% of it is especially those on YT and Twitter. In time it will be interesting to see how that group manages their illness.
ME/CFS is not a disease, it's a syndrome cluster of symptoms...awyas something underneath. To me, this is more like what I called it when I got it severe in 2020 fresh off the front Iines as nurse ...covAIDS.
I believe this as cancer loves acidic body, too. Could you do video on covid triggered pulmonary fibrosis? Thanks.
Thank you for making this video and the research that underpins it
I wish you all the best with your research
Thank you so much Gez. Your channel is the only place where I have found this information. After watching your videos, I bought pH test strips and I am super acidic. I started drinking electrolytes and alkaline water and have been feeling better all of a sudden. Thank you again. Words aren’t enough to describe my gratitude for the information you have been putting out there.
I’m so happy to hear that!
Wow! Did you recover from fatigue as well? I have this annoying lightheadedness, i think it is lack of oxygen. I dont know what to do about it
What kind of ph test did you buy? I am in argentina and would like to try
Hi , first to comment here?...
❤ love the shirt! Looking well.This acid - base imbalance and subsequent hypoxia and cellular anaerobic respiration sounds a very probable hypothesis. Another very well presented and informative video, helping piece together covid' s sleuth tactics.
Haha, thank you!
I’ve missed your videos buddy; thanks for everything you do Gez!!
Thanks Stephen!
What a wild ride LC is but everyone is slowly piecing together the puzzle!
Things that have helped my recovery so far and gotten me out of a bedridden state:
1. Break up the microclots and improve micro circulation with Dr Laubschers triple anti coagulant therapy for 30 days!
2. 100mg TTFD Thiamine + B Complex & Electrolytes (magnesium/potassium) each day! Thiamine & B vitamins support the mitochindria function and also provide the fuel for the autonomic nervous system - If the tanks empty of acetylcholine we run on sympathetic and use anaerobic energy as mentioned in this video and the by product is lactic acid & acidosis + adrenaline and cortisol.
I’m 2 weeks in without a crash so far, waking up at 7am with energy, sleeping from 10pm till 7am. Brain fog, POTS, Dysautomnia, Parasthesia, Fainting spells all gone. My only symptoms left is still feeling a little off & what’s happening with my chest pain and hoping a cardiologist can resolve that in a few weeks!
Great news!
@@RUNDMC1 Thank you so much again! I wouldn’t be where I am now if it wasn’t for all of your hard work and research bringing everyone together and sharing it with the world!
How long did it take you to recover? were you drinking electrolytes everyday?
@@asmazak I felt the change within 3 days and Yes I drink and EAA+BCAA complex each day take 1200mg of Magnesium & 3700mg of potassium
Good to see you back Gez. Great presentation.
Thanks Ed!
Great to see you back, Gez! Love that Das Ding poster in your background. Also, love that shirt combo :) I've noticed low (5.5 - 6.0) pH in my urine for the past couple of years regardless of exercise levels. Never tested before that. LC since March 2020. I'm mostly well and exercise regularly with the occasional crash. I've had far fewer crashes and bad days since I've been taking 5mg daily Pravastatin for the past year+.
Thanks Scott! Statins do seem to help quite a few people.
This ties in nicely with earlier stuff about COVID messing up your breathing and people having to have therapy to learn how to breathe correctly again. Good luck with your research.
So happy to see you Gez! You look well-rested!!
Thanks Leslie!
I have speculated that this is an issue of metabolic acidosis as a compensation for respiratory alkalosis when people were over breathing during the infection, with the added anxiety around the global issue. Which would lead to a similar outcome that this hypothesis proposes
I literally shouted THANKYOU when you said about the soul crushing fatigue, "it sure ... isn't deconditioning. " ❤
I have this every single day and dont know what to take to combat it.
It's great to see you again Gez. Im happy to see you took the last few months to yourself. I hope your recovery is going well. Thanks for all the work you are doing for us in the LC community.
Thank you Paddy!
@RUNDMC1 do you eat a plant based diet Gez? I'm bad for dairy and meat and all sites I've researched on an alkaline diet point to plant based, nuts, seeds etc?
@@paddyconroy1147 plant-based makes me worse and more anemic!
@@Jennifer-gr7hn wow, really?? Thanks for this.
Thanks a lot !
Quite possible. Thank you Gez!!
Makes so much sense to me ! Now I know why taking 60mg of omprozole and 40mg of nexium helps more then anything seems too ! Dr's look at me like I'm crazy when tell them I feel like I'm dealing with acid constantly. I've had upper gi , colon scope , couldn't find a thing but I knew it was there something their not seeing . Thank u I don't feel so crazy now !
Hi Gaz. Happy to see you after a while. I agree with your acid-base imbalance theory. I am going through this phase, I want to tell you what is helping me for this is Benfotiamine high dose. Post-COVID POTS, low energy, sore muscles, neuropathy, and acidosis all are symptoms of Bery-Bery triggered by Covid infection. I request you to start your research on it, you can change the life of millions.
After covid i was diagnosed w fibromyalgia, no family history..many of the same symptoms you listed...wondering if i have a wrong diagnosis. Def believe it was triggered by covid, but my oxygen levels are good, 98, 99...
@@PureExistence1 Without Thiamine cells can't use Oxygen to make ATP (energy), oximeter usually shows full saturation.
@@balwinderbhullar2013 hello, and thank you so much for your reply🙂 So taking thiamine helps the cells to uptake oxygen so ATP can make energy? And the oximeter only shows saturation, not whats going on in the body with how that oxygen is being used, right?
Brother, i just got my benfotiamine... what dose are you using?
@@PureExistence1 I am taking Benfotiamine 600mg, but I advise you to start from 100mg and gradually increase as you tolerate it. Take it with all B vitamins and magnesium.
Good to see you back. I hope you are feeling better Gez
Thanks Thomas!
Waiting for part II to find out how to deal with it. Thanks.
I have been vaccine injured since July of 21 after 1 dose of Pfizer. I am in several groups that include both Vaccine injured and LC and they seem to have overlapping symptoms. I have been diagnosed with dysautonomia and also have vision issues, burning skin (SFN), PEM, Vertigo and a hand full of other symptoms. The last two years have been tough but I am hoping better days lie ahead.
Thank you for adding your voice to the Long Covid efforts. Vax injured is logically very similar to Covid illness persistingy injured, as we are dealing with the same ingredients, the same agents of attack on our immune systems.
Diagnosed vax injured, it triggered PMR (polymyalgia rheumatica). I felt awful for several months and I'm being treated today with prednisone. It works! (Google: polymyalgia rheumatica and covid vaccine) The NIH has published on it, and it's mind blowing.
omg, I am the same. One pfizer in July 2021 and my health is destroyed. I am still getting worse.
I said in march 2020 around the time I got it, just came off working frontline as a nurse...I said "with this agenda, they're going to try to get us by injection or infection...."...the shot wasn't yet out. Of COURSE the symptoms will be the same. The poison is the damn spike protein. On..purpose!
1 dose of Pfizer caused me all these issues, I was threatened with UCMJ action by the US Air Force. Glad I left but the damage hasn't.
I RELATE SO MUCH WITH THIS WOMAN. Long covid and reinfected a lot. I would love to hear more about others who have gotten sick a lot. I get covid every few months.
When this journal article came out a few weeks ago, I read it and started changing what i was eating to try and reduce acid in the body. It's definitely made an improvement to how i feel and my energy levels. And to an outside observer it's also a "healthy diet" so I'm going to continue to roll with it. I just add it to the list of all the other small changes I'm making to see results. A bit like British cycling's approach to "marginal gains" 😊
Could you kindly offer examples of things to decrease AND increase intake of?
Thanks Gez. As a March 2020 sufferer I’ve followed you for years. You look so much better and I’m pleased to say I had my first day at work yesterday for 38 months. I’ve noticed on ‘ bad days’ that I need to drink a lot of water. Wonder if that’s the body’s way of trying to correct the imbalance? Look forward to Part 2.
Might well be. Great to hear you’re back at work Denise!
It's great to hear new information and ideas but unfortunately we're still no closer to getting treatment. When I mention long covid, or research, the GP's just dismiss me and don't want to know basically. They try and pass fatigue off as depression! Yes I’m now down because my body doesn’t work properly, I don’t know anyone that would just go on as normal, if they felt like they’d woken up in someone else body.
I'm exactly like you
@@barbarasmith4560 Sorry to hear that. I hope we can all get some help at some point.
My path so far has been an functional medicine therapist,
posh supplements. Muktivits P5P, Adrenal Cortex , Calcium Magnesium Butyrare.etc for GUT SUPPORT
Now NATTOKINASE VASCANOX ARTEROSIL For vascular support.
This acidity lactose aspect adds a new level.
Thanks so much for this information , am still battling symptoms after the covid . Would like to know more to help myself.
It's good news for people like me who have had CFS for many years. For me, since 1985, back when the doctors told me it was all mental. With so many people at the same time having an identified virus, there is actual headway being made to find out what causes, and hopefully, how to treat these post viral chronic conditions. When I hear of the lactic acid link, I'm thinking of how exercise brings on lactic acid, and how it relates to the failure of my body to rebound normally after exercise.
I still struggle with symptoms. body aches, sudden fatigue, digestive distress, incontinence, etc. Once I began fasting symptoms improve but now when I eat I am almost immediately overcome with symptoms again. I have found that drinking warm- hottish water with a dash of salt helps instantly. The temperature of the water effects different symptoms. Hot water over 110F helps digestive issues, cooler water 104F helps with body aches, water near body temp bekow 100F helps with headaches. The amount of added salt is miniscule just a few granules in 12 oz water. Chugging the water all at once is required, no sipping. Filling the stomach rapidly makes for the rapid recovery. It also works as a prophylactic in advance of physical activity allowing me to teach ski lessons and coach other instructors with no major discomfort. I must still regulate how aggressively I ski and demonstrate keeping my self well balanced so I don't have to make large recoveries to balance but that's just good skiing.
My goodness, what a TREASURE OF A CHANNEL. Time and time again
I would not disaagree if anyone thought Gez (and all these incredible science pros) deserve recognition of the highest order.
I would love tom to see you all get MBE's years down the line .
As for symptoms i wonder if this explains the THIRST ive had for almost THREE YEARS NOW , since infection. And apoarently DRINKING CARBONATED WATER does play with the CO2 IN THE BLOOD.
I just have to see if for the better or worse ....have not yet worked it out
+1 on the raging thirst. Sometimes have to drink 3 pints of water overnight.
And thank you for the kind words!
@@RUNDMC1 it's true Gez . You've been a beacon during times of national tragedy.
I have been out of action for 2÷ years. Having always been fit, with a career In the creative field etc.
Now I struggle to even form sentences!
I admire you being able to run this channel create content of high complexity ,etc
@@a.o.marcos9555 I do it on the good days! Cognitive issues still very much present for me
So interesting!!
After 2 years of living with post extertional malaise this sounds very plausible. Also, the fact that not drinking enough water used to cause chest aches. Also, breathing exercises had helped so much.
This is suggestive of class A lactic acidosis caused by lack of oxygenation of tissues.
Its Dysautonomia/ME/CFS. Follow a dysautonomia recovery protocol. This channel is worthless.
Jabs????
There were no jabs when I got covid, and thus long covid.
I’d love to get tested for this
It would proberly explain, why lots of endurance sports people ended up with long covid as their bodies have adapted to latic acid build up to the max their bodies could handle, then long covid pushed it over the edge.
I think it overloads the cori system in the liver and messes up the energy system.
Any I feel like I'm making progress after over 2 years, I'm not getting heavy relapses anymore, if I do it's more like an afternoon nap and I'm back to normal the next day
Hi Gez! Welcome back. Missed you a little. It seems you got back on your bicycle? I got better while using Maravroc tried my bicycle for 1 min and induced a 2 week crash. Searching for my baseline still.
Only an ebike! I actually do ebike conversions as a sideline to pay the rent :)
The NIH in the US has a $1 BILLION Long COVID research budget. These guys should find a US institution to partner with asap and get their trial funded.
The November '2 NIH published paper on Pfizer vaccine and PMR is revealing, and it seems that I'm also dealing with PMR (polymyalgia rheumatica). Google PMR and COVID.
Amazing video giving me renewed hope at yet another lowspot. Cant express enough how grateful I am for this ❤️
1. Does anyone have any lactate meters to recommend?
2. And, is anyone knowledgeabe about what treatment that entails?
For me, the biggest puzzle in Long COVID has been the relatively high incidence in seasoned athletes. The remarkable prevalence of marathoners and half-marathoners in Long COVID groups has always puzzled me. Perhaps CO2 is a factor; your bodies are accustomed to producing large amounts of CO2 and expelling it rapidly in respiration. COVID - particularly in the original form - interfered with respiration, possibly raising the residual CO2 level in the blood and tissues.
It is just a thought (and not completely thought out at that) but we have known for years LC is not All One Thing. This definitely could be an important thing.
I think it’s also due to a body that’s got used to running at high stress - can easily be tipped over the top into dysfunction, whether that’s nervous system, immune or metabolic function
@@RUNDMC1 Absolutely.
Covid 1st time March 2020. Then again in December 2020 and September 2022. Long Covid has now got me Costochritis in September 2022. May 2023 now diagnosed with Fibromyalgia as well. Now have trouble with walking.
What are the treatment for lactade ?
This reasonates with my lived experience. When i try to walk at m6 usual pace or climb stairs my quads cramp and then I get breathless which seems like hypoxia to me and definitely feels like lactic acid as if I'd done a hundred squats!
I have had progressive, sustained improvement from taking Monolaurin. I heard about it when Dr. Been talked to dr. Stephen Philips. Basically, it is the component of breastmilk that does all the anti-microbial work. Fortunately also found in coconut. Takes care of the viral, spike protein persistence issues. Unfortunately, the Herxheimer reaction can be unpleasant, lasted almost 2 weeks for me.
Looking forward to part 2. Quick google, looks like a low meat high vegetable diet.
How much do you take, and is that on a long-term basis?
It sounds like the same issue with PEM in chronic fatigue. I have been trying some recommendations from the phoenix rising forums that adress PEM, with some success.
What recommendations are they could I ask?
Gez thanks! But how long do we have to wait for part two??? getting desperate here. Even though I haven’t been able to work since March 2020 I could at least more or less take care of myself and do a few things while the hubby was at work but in these last few months it’s been so much harder to even do that! i’m trying a million supplements again just out of desperation, some old and some new butt just spotting your video gives me some new treatment to hope for🙏 just don’t keep us on pins and needles, ha ha, too long😂 Can’t thank you enough
Only a couple of days :)
And nothing is a magic bullet - but anything we can do to give even some improvement is worth it :)
@@RUNDMC1 absolutely🎉
There is another theory that needs way more attention given the serious implications that it could create.
It is called the Amyloid hypothesis and could explain why the neurological symptoms are persistent
The summary is on Reddit, but the link gets deleted by CZcams
That would explain the shortness of breath, weird breathing sounds when I move my torso and weird fibrous sounds when I stretch all over my body.
Second question- how would the research into low dose methylene blue impact the lactate levels in cells ?.?
where could we get a home test kit for lactate, is it similar to glucoes meter?
There are also studies that suggest that covid may trigger prediabetes and diabetes.
Me. II had long covid symptoms for 6 mounth now.
Noticed that symptoms depend on what I eat. I don't eat sugar or anything particularly sweet. Have a Normal BMI.
Could be acid imbalance, could be prediabetes. I really don't know.
What I do know is when I cut my carb intake to about 100g/day about 1200ccal. Eggs, meat and lots of salad.
I feel better and can exercise now.
Hope this helps someone.
Live long u all
Gez, big thanks for all your efforts for helping us and for your great book! What is your opinion on dr.Patterson protocol, did you try it or made the test they are promoting? Someone in this chat has some experience with this protocol? Good luck & much love
Patterson protocol is expensive and hard to get prescribed in the UK - results I’ve heard of are mixed.
Can anyone please tell me which lactate meter can we buy to check our acidity levels? Thanks so much
So when is the next video where you talk about treatments? What are the potential treatments?
Early next week
If there are such fluctuations in the acid base over 24 hrs, I wonder if this affects the absorption of Nattokinase?
I know that the digestive enzymes need different levels of acidity but do the systemic enzymes also, once they get into the intestines past the stomach acid with the protection of the enteric coating?
I have been taking Nattokinase for 5 months, had to stop for a week and declined into fatigue and PEM. Started again and within 3 days was fine.
Anything you have learnt about taking Nattokinase and any relationship with this Acid-base research would be wonderful. Thank you. D
Not aware of any knowledge base on acid/base and natto, sorry!
What are reputable sources and brands of finger prick lactic acid test? Please answer? :-)
would your ph in urine show acid base Disruption in the body or does it have to be lactic blood test? if so any suggestion in home testing options? thanks
What is the treatment option? I did ABG test and have low pO2.
as always thank you Gez for your work. tell me if you ever come to the dolomites with your DMC :) i would love to welcome you as our guest
Very kind of you - thank you!!
This could be huge step forward.
Where can we get those finger prick acidosis home blood tests please?
How would one go about doing this home testing?
I just tried the ph.drops & dare i say ,i think it helped.i hope & pray.❤😮😮😢😢
Thank you Ged for all you share with us. Wondering if you will be looking at treatment with nicotine patches? I’m seeing a lot of posts about this now.
Pretty sure nicotine gets converted into niacin.
Yes - theory is interesting, anecdotal reports mixed so far!
@@RUNDMC1 Sorry Gez, not Ged! Brain fog … you know how it is! 🤪
Could D-Lactate Free Probiotics be helpful ?
This seems to have some strong similarities with the way cancer uses glutamate and fermentation to proliferate. Could this be a similar process?
Just been hit with my third infection and it’s a bad one. Already got terrible LC. Why does this virus affect some so much worse than others? My brother hasn’t even had it once!
Rest up Jamie - don’t rush back to activity once you’ve got over the acute infection.
@@RUNDMC1Good advice thanks 🙏. It’s definitely a mistake I’ve made before.
Could this also be the case in covid vaccine injury? A lot of my symptoms are exactly the same as some people with LC. I just started telling doctors it’s LC so I can get actual medical care.
how do we order these home tests?
EBV does that too. It makes it impossible for the cell to 'breathe normally'. It turns into anaerobic metabolism which causes the same issues like lactic acid build up causing PEM, muscle weakness, total exhaustion and brain fog amongst other. But how to turn of this anaerobic mode?? Is it the virus that does that or our response to the virus? Ps. Good to see you Gez:)
Thanks Melanie!
Post inject noticed cycles of pots, tachycardia, and bp changes. Trip to ER (heart rate over 188 bp over 165/135) showed bottomed out bicarbonate and acidosis.
All of this has been tracked with at home bp and ekg monitor. Looks like a fancy rollercoaster from Hell.
Given the finding, each time tachycardia episode I found small amount of bakingsoda was helpful.
Food sensitivty? Found acesulfame potassium, sulfites, and artificial colors all exacerbate it.
Appears calcium handling and the bicarbonate buffering system is disregulated. Once the calcium cannot move the muscles fail to function correctly.
Noticed that magnesium supplement could also trigger the changes as it exacerbates the calcium balance.
Vit k2 mk4 with calcium and vitamin D seems to be fine. Without calcium will start the issues.
Magnesium is a sometimes problematic. Likely calcium is to low.
Coffee -- add 1/8 to 1/4 sodium bicarbonate to a pot for acid buffering seems to smooth out.
Water with lemon juice, salt (1/4 tsp) and potassium citrate (1/8 tsp) also helps.
The big issue is this only solves heart issues for normal activity. Still cannot perform strenuous activities and still appear to have mitchondrial based energy issues.
Coq10, thiamine(hcl, benfotamine, and ttfd), riboflavin all help some.
Mitchondrial support -- Looking into calcium pyruvate, disodium succinate, urolithin, boron, and methylene blue as next steps.
Did you take paracetamol or ibuprofen or similar which could interrupt the healing process in the body?
Can this help ME CFS with va x injury too possibly?
Potentially yes
March 2020
Now been experiencing very sweet taste periodically since Aug 2022. Wondering if this is linked.
Anyone else getting new symptoms a few years in?
I hope they look into PATENT FORAMEN OVALE(PFO) as a cause
Where and who does this testing??
Consider how much gas loss during centrifuge and plasmaphorsis ?
My long covid flares greatly improve with microdose of pepto bismuth when it flares. Also occasionally microdose at night. Sunlight and vitamin C foods help as well. Half of pain associated with flu resides in gut.
Please! If there’s treatment let us all know!
But what if you treat this disorder and thus lessen the symptoms, which might be your body‘s warning signal that you need to rest? If the underlying problem is the oxygen supply in your cells f.e., and you dont realize that you are over your boundaries because you have dealt with the acid? (Sorry, my english is not adequate.)
That can not happen,don't worry.
Whats a treatment of you have high lactic acid?
tune in in another 5 months.
Where to test lactate levels
I have LC since 1,4 years ago, I developed a kidney stone and my urine has been much more acid, I'm sure the cause is exactly this acid-base imbalance you well explained
Btw Gez, just a wonderful video, very well explained and edited. Huge THANKS!
yes, many of us are developing them -- acidic 101! Lemon juice eery morning through the day!
I have acidosis what do I do
Treatment is probably Bicarb of Soda and Beta Alanine. Athletes use this to buffer lactate acid. The amount of Bicarb required by athletes for any noticeable performance change is several grams, which is intolerable by most people. Beta Alanine tends to be used more in gym based workouts to push through the burn during high rep sets. Ideally cellular respiration needs to be fixed rather than dealing with the byproducts but it may break the inflammation cycle and prove useful for some. Hopefully it''s not a push to sell some of those dodgy alkaline diet fads but i think Gez is quite good at sniffing out pseudoscience.
I do my best! We talk about treatment in the next one
I go to work on Monday - my plan is to wake up drive in and rest in car for 15 minutes and then work take breaks every 2 hours and then drive home and rest and eat dinner than sleep
I have PEM and my idea is if I get a crash at all I’ll just quit. But can it make me permanently worse???
Do you think this is a good plan / I wish I had 6 months to just rest but I’m getting pressured back into this :/.
You think I’ll be alright?
Any tips or advice or supplements?
Appreciate all your work and support !
i guess it's good you dont have problems being on the road.
I do… just gonna drive slow
@@Anonymous-hi7oh If you have bad spells when driving, or being a passenger, it might be worth looking into wearing a mask to reduce your exposure to the air inside vehicles.
The air inside vehicles is generally far worse than at roadside for pedestrians. Exhaust fumes are primary pollutants, their evolution to secondary pollutants, photochemical oxidation, plays around with the oxidative process of your cells causing an aggravation of the inflammation that is the reason you suffer from long covid.
If you suffer from repeated PEM you will need to lay off whatever it is you’re doing - it can make the condition worse. So try to make as many mitigations as possible but if you can’t get through it and maintain your baseline then stop sooner rather than later.
I'm on week 3 of covid and forced back to work. Really struggling with the fatigue. Might get fired if I call out again.