The Genetic Link to Abnormal Clotting in Long Covid | With Dr Jordan Vaughn
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- čas přidán 30. 05. 2024
- In this film, I talk to Dr Jordan Vaughn about his experiences in diagnosing and treating abnormal clotting in Long Covid, and why fibrin breakdown might be key. In fact, there’s an off the shelf test to discover why you might have a genetic predisposition to struggle to break down this particularly nasty covid related sludge in your blood.
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Before I caught Covid in March 2020 I was a filmmaker. I’m not well enough to go back to work yet (shoot days are brutal), but I’ve decided to indulge my passion by breaking down the hottest recent films and TV shows (from an insider’s perspective with 20 years in the industry) to describe exactly how they work. Sound interesting? Then subscribe to my second channel! ( @thescriptflip )
Here are some links:
5 Reasons Why Top Gun Maverick Crushes the Original | Film Director Breaks it Down:
• 5 Reasons Why Top Gun ...
Why Succession Shouldn't Work at All, But is Somehow the Best Show on TV:
• Succession Shouldn't W...
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The Long Covid Handbook (Feb 2023) by Gez Medinger & Professor Danny Altmann (and published by Penguin Books) is now available in paperback, ebook and audiobook. A singular resource that brings together everything patients, clinicians and academics have learnt about the condition to date, as well as lessons from sufferers and researchers of ME/CFS and other chronic conditions. It offers world leading expert advice on understanding, managing and treating Long Covid. It is available from the following links.
US: a.co/d/0gvkJCU
UK: amzn.eu/d/9KjurGb - Věda a technologie
At least SOMEONES interested and excited about helping people miserable with Long Covid!
Seriously
I know, it sometimes feels like I am living in a third world country. We have been pushed into the margins and people don't realize how serious this is. Thanks to Gez, we can do more than slowly die, we can try the info he provides.
If you took the jab you know why you have long Covid!
Agree...there seems to be little help here in Arizona. I found a sports medicine practice that offers treatment in Phoenix but it took over 2 years of looking. The University in Tucson had a program that was full with patients and the Mayo Clinic in Phoenix didn't take my Medicare insurance.
@@randolphwilliams2365 After waiting over seven months post Dr. referral to UCHealth, I did complain and was immediately responded to. The Dr. put me on Naltrexone, an RX compound. It is helping, took down inflammation, pain, at first more stamina, then some energy, tho pacing is still necessary. Regardless, I am really hopeful now. I'm sure it doesn't work for everyone, but it has helped me. Of course I do the pt recommendations too. I wish you wellness and positive progress!
I've been receiving treatment for Long Covid from Dr. Vaughn since March 21st. He is one amazing Doctor and is truly trying to help people.
Where is he please? Name of clinic? I’m losing hope.
@@MinouMinet MedHelp in Birmingham, AL
What kind of treatment is involved in your case?
@@waggawaggaful Thank you!
What does he do for treatment for the blood clotting etc?
Based on recommendation in in one of your videos, I started nattokinase and serratopeptase in February. substantial increase in energy levels within a month. thanks for the work you are doing!
Great to hear that!
Same here and less crampingnin my legs
what is the recommended dosage for both supplements? Thanks
Serratopeptase aint good long term. It's like any other blood thinners out there.
What is the serratopeptase for? Do you have to take it in conjunction with natto?
Thank you! Gold mine. Love these docs from outside the original system who can still think, troubleshoot and discern instead of just blindly follow protocols. These are the truth heros fighting for people’s health! A million thanks!
Many of the symptoms of coming from the inoculation
So two and half years later , i wish i wasn't having to watch this video but alas like many others , im still battling crippling lc issues ... So thankyou so so much for making this video and continuing to try and find solutions .
Best of luck with your recovery Ella!
@@RUNDMC1 ditto
Keep pushing for answers I too have suffered over two years without diagnosis I've said all along that I have something that came from covid I can't find a Dr that specializes in this area
I began the nattokinase and serratopeptase only one week ago! Am stunned at my swift improvement, never imagined going from a persistent state of depletion to having some energy and some endurance for the day. Still have a long way to go, but am so grateful for the information. Also added the Tocotrienols a month ago. I hope others have improvement too, I had truly lost hope! ❤
What dose?
@@AngelofD69 I switched from 1000 units E to Tocotrienols because someone on here said regular Vit E was contraindicated for LC, and they suggested Tocotrienols, which is still an E. I take 300 mg daily and could probably handle more, but what I am doing presently. Found the Nattokinase and Serraptase combined in one capsule and take one a day, from Solaray, reputable company. N/S is 3000 FU each. My body was used to high levels of the E and provided pain relief for arthritis, thus my decision to slowly increase the Tocotrienols up to 300 mg daily. I may go higher, but right now am feeling improved after only a week. I found it at Natural
grocers/Vitamin Cottage, probably available elsewhere as Solaray has been a reliable company for many years. (to me). There were other brands, I went with familiar. I hope you have same results and wish you the very best!
Nattokinase also suppresses some viral & B/T cell DNA replication, presumably by interfering with one of the kinase pathways involved with phosphorylation, so it's probably best not to take it all the time. NAC may also be helpful.
its worm poo i tried it and got hives! be careful😮
Nattokinase is supposed to be taken on an empty stomach. Food will keep it from being absorbed into the body.
Just listened to this in the sauna....helps me bear the heat ! Gosh , how far you've come in helping find answers for yourself and the LC community from early days in 2020 asking," what the he'll is going on !? " ...to eloquently explaining many symptoms in terms of chronic fatigue / PEM, hypoxia , MCAS, micro clots and now genetically programmed abnormal fibrinioytic pathways. You've done amazingly, well done !😊
( Any typos, can't see well, it's dark in the sauna ! 😅)
Don’t forget viral persistence…
This is what terrifies me. I ALREADY have a genetic blood clotting disorder that almost killed me twice
Life is in the blood, attack the blood attack the life. So many metaphors here. It's good to know there are some doctors looking in the right direction
Yikes. He was kind of describing me in his typical patient profile. Three years on from my March 2020 illness, I'm tremendously improved, but not fully well, either. Starting daily baby aspirin about 6 months ago was a major turning point that allowed me to do cardio (beyond gentle walking) without crashes for the first time in three years. I don't think the asprin would have been as effective if my doctors hadn't teased out and addressed some genetic and autoimmune issues first. And it hasn't completely repaired my exercise tolerance. I was in the gym 4-6 days/week before I got sick, doing a lot. Now i go a few times -- which feels like a wonderful victory! -- but I do extremely short, low intensity workouts. Spending an hour at the ice rink, or doing a full hour of yoga with people 10-20 years older than me will still drop me like a stone 24-48 hours after the exercise. But my overall energy is better, and my recovery time from new viral infections is much improved. I've recovered from recent colds on the same time scale as "normal" people in my family, instead of being kicked into a 2-6 week long-covid relapse. That by itself is a huge improvement! Anyway, I'm not all the way well, but I'm still hopeful that I'll get there by assembling the puzzles pieces. Abnormal clotting seems to have been a big puzzle piece for me. Thanks again, Gez, for assembling so much research in a place where it's easy to digest and share with doctors!
Best of luck with your continued recovery Hanna!
Do you just take 1 baby aspirin daily? Would you say you are around 80% healed? Hopefully...
@@ManTimeT.V. I normally take two per day. If I’ve exercised a bit too much and think I’m at risk for a delayed crash, I’ll take one or two extra. Sometimes that and proactive rest can prevent a problem. 80% sounds reasonable, in terms of where I’m at. Maybe even 85%. I should probably experiment with nattokinase instead of aspirin and try a few other things my doctor has recommended. But I’m basically holding steady and managing work and increasing exercise in a way that looks outwardly normal . . . So I’m hesitant to rock the boat.
@@hannasizemore8028 thats great you are 85%. I have felt that well here and there as well. But I seem to sit around 70-75% most days now, with very few crashes etc. I have worked out on occasion but I don't seem to keep it very steady. I need to get back into that slowly again and build up over time. I work full time and also on call with work every other week, plus I manage to take on some small ish side jobs as well. So I can manage in that sense but I just want to get my breathing back to normal. Wondering if natto could possibly help with that.
@@ManTimeT.V. Honestly, I've been closer to 75% the last two days because I exercised too much on the weekend. And though I technically work full time, it's not the kind of full time I used to work. I wish I could pause work and kids and various things for a month or two (or six!) and make a dedicated effort toward another round of improvement, instead of just hanging on. Anyway, the aspirin was one thing that helped me creep back to regularish exercise. The other thing was low dose naltrexone. That addressed more of the autoimmune stuff, and it only works for some people, but I was one of the lucky ones. I had no idea how much constant joint pain and gut pain I was having until the LDN turned it off. That started a virtuous cycle of improved rest, better mental clarity, less fear of exercise, etc. At any rate: Good luck! I hope the anti-coagulants give you another boost!
Thanks Gez for not giving up the search. Know that you are appreciated.💕
Thank you Gez for this new and updated info. It seems like scientists, doctors and virologists are slowly but surely piecing this long covid puzzle together. I am still hopeful that they will figure this all out, i just hope its sooner than later. New long haulers are becoming every single day in this world.
Many of the symptoms are coming from the inoculation
Thank you. I just sent a message to my provider to see if this test is available. I am about at the end of my rope here. Been going on 2 1/2 years after Covid twice~!
Which test did you request?
@@browneyedgirlFL67 I requested the Plasminogen Activator Inhibitor-1. I have not heard back from my provider yet.
That's my doctor!
Thank you Dr. Vaughn!!!
I am a board certified health coach and public health educator. I have lots of people who need to get their providers to order these tests because the symptoms they describe to me are consistent with what you are saying 👌💯🙏
Thank you Gez!!! Providers may be willing to order this test however they may not be able to treat it if result comes back positive.
So grateful for your work, Gez. Purchased your book and have watched all of your videos. You are spectacular!!!
That’s so kind of you - thank you Martha!
Thank you for sharing, this is exciting to have *something* to possibly move forward with. Every piece of the puzzle is necessary to solve the puzzle!
Dr. Vaughn, we reached out to your clinic 2 weeks ago and still have not heard back. Please reach out to us, my teenager has been in this LC mess for over 2.5 years.
So glad you are back.🙂 Your previous guests (Resia Pretorius) often mentioned ME/CFS along with long covid. Will you have them back to give updates? I have improved since taking Nattokinase, which I heard about on your channel, so thank you so much!!
How much and how often?
@@karenm7433 same question.....I took it for one month , one pill on waking up and on going to bed, and kind of felt an improvement but really, all the weird symptoms were still there,,,,
@@karenm7433 One pill a day in the morning.
@@violetasuarezcapri4258 I take one pill a day in the morning. I have improved quite a bit, but still have many of the symptoms. The fatigue has improved though.
@@jaynesierakowska3120 would you recommend a specific brand and dosage? TY!
I've been following Dr John Campbell for a couple months. He really breaks it open.
What i wouldn’t give to have a doctor like this treating me !!! I’ve been sick for 3 years now. It took about 8 doctors but finally after 2 years and 11 months i was diagnosed with long COVID. BUT.. I’m still not being treated. Internist is submitting to insurance for approval to COVID clinic. I will probably be denied because it’s medical. I have not been able to work since getting sick. I have daily ( no exaggeration ) heart palpitations of varying degrees of severity among vertigo, tremors , breathing issues , sweats , tingling hands , severe fatigue. Life has been pure HELL on earth. Not sure how much longer i can fight.
I feel you. I used to be healthy, active, vibrant full of energy after covid & still have long covid almost 2 years now. My parents are in their 80's, stronger, healthier, more stamina & endurance than me. Struggling for daily activities
I'm literally in thr same boat . I feel like im going crazy
Really interesting Never ear about the 5G/5G genetic testing linked to long covid before. But it seems that MTHFR mutation C677T " Patients were genotyped for genetic variation in homocysteine metabolism implicated in hypertension, a common covid-19 co-morbidity reported in patient found to be homozygous for the risk-associated MTHFR 677T-allele."
This study in a Turkish population (PMID 36647888) found "No evidence of a correlation between the severity of the disease (covid-19) and all five thrombotic mutations was found, (Five polymorphic loci Factor V Leiden (FVL), FII G20210A, Beta-fibrinogen G-455A, and methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C.
@@juliemottainai6638 Isn't that study limited to the acute phase, not for risk or severity of Long COVID?
As a former marathoner who is also female and 2 years into long Covid, this resonates. So what do we do?!
Nattokinase if you’re not on it already
@@MrKelso85 I rook it and saw no major change. Surely its more complex than just a pILL?
THE BODY seems to be stuck in perpetual production of lotsnof nasty things
@@WomblingWombat74careful with aspirin. It can lead to brain bleeding issues.
@@andrewstrakele6815LOTS of good info there Andrew. It has to be attacked from multiple angles and stress, nutrition and sleep are vital for it.
I'm an overtrainer/overachiever of course. I train and push thru things. It's how I was raised and allowed me to perform in life but am very aware that I've hurt my body to no end by putting it thru constant physical and emotional stress non stop for 35 years. I also have family priors of heart and autoimmune issues on both parents' sides.
@@violetasuarezcapri4258 - Hi Violeta! You are unfortunately correct. Recovery from Long COVID will require more than just a Pill. It typically involves Inflammation of the Brain which causes dysfunction of the Autonomic Nervous System - the Body’s Control Center. Body functions like Heart Rate, Release of Hormones, and Digestion, performed automatically by the ANS are disrupted , resulting in a myriad of symptoms throughout the Body.
As I discussed in my previous reply to @Karen M74, I believe Long COVID is the end result of Chronic Stress, causing a complete breakdown of the innate Immune System. The acute COVID infection or vaccine injury is merely a trigger resulting in the chronic dysfunction of an ALREADY COMPROMISED Immune System. It is a Metabolic Disease that requires changes in Lifestyle as well as Mindset.
In the video, Long COVID: Life is Not Fair, JUST ROB discusses how you need to Believe you Can Recover, Choose NOT to be a Victim, and CHOOSE to be Happy to eliminate the repetitive cycle of negative thoughts and develop the proper Mindset to begin Recovery. The video, Long COVID: Healing With Polyvagal Theory is also worth watching.
After adopting the correct Midset, the next steps are:
- Reduce Chronic Stress by becoming a Student of Improved Sleep Habits to Maximize Deep Sleep
- Manage Stress through Meditation and Breathwork
- Become a Student of Proper Nutrition by following a Low Carb, Low Inflammatory, Whole Food Ketogenic Diet with Intermittent Fasting (as recommended by Dr. Eric Berg).
-perform occasional 3-5 day Prolonged Fasts to stimulate Autophagy, Stem Cell Production, remove/replace Damaged Mitochondria for increased Energy, and completely rest your Immune System.
- Become a Student of Supplementation to Optimize your Immune System (Dr. Eric Berg offers a free online course).
Thankful for Dr. Vaughn.
Thank YOU, Gez! Briliant, as usual!
Thank you Anamaria!
But what percentage of his patients recovered with the treatment??!
I sound like the demographic he was describing (very healthy and running half marathons, skiing, climbing, etc before covid, now have to use a wheelchair to leave the house) and I am 4G/4G. However, I'm 3 months into triple therapy and my clotting markers are still off the charts, with no symptom improvement yet, so just looking for some hope! Appreciated the info that the 4G/4G genotype makes such a huge difference (10x higher PAI, wow!) so really hopeful that adding nattokinase recently will start accelerating things for me.
Anyways, thanks for doing this interview! So grateful for Dr. Vaughn's work and my own doctor's collaboration with him - I am convinced this is a major part of the puzzle (if not all of it) for me and very lucky to get triple therapy, just hoping so much that it will start working soon
What is all Included with this triple therapy? Have you started natto and or aspirin?
Eliquis, Plavix, aspirin and adding natto last 2 weeks
@@jenellewful do you have to get all these from a doctor? I have nattokinase here on hand but have not yet taken any.
@@jenellewfulany issue with bleeding ? What grade is your microclot
Yes I seem to have this problem and also worked for years in hematology microbiology and immunology. Thank you for your detailed lecture video
I'm so glad I found out about you Dr Jordan Vaughn and you have given me hope I can get in touch with you or a doctor you can recommend me to get in touch with. I've been suffering for almost two years and I'm not getting any better and my life is been turned upside down and unable to work. I know you are a busy man but you are my only hope
Clotting with the jabs is not abnormal, it’s the norm
this was very interesting, thank you Gez and Jordan.
I developed bilateral embuli in March 2023. Clotting high in blood, high inflammation. I am on Apixaban x 2 daily and slowly recovering. An awful experience all round.
I would like to approach my doctor about me possibly having this fibrin breakdown issue/polymorphinism. Is this blood test done on the NHS? What is the test called in the UK, I am prepared to go down the private testing route!
I work in a clinical flow cytometry lab and we are working on the same issue. It would be interesting to do a collaboration with Dr.Vaughn.
Longcovid can cost people hairloss and career loss - that can be valued at up to 100000d easily. And other treatments and clinics can be about the same or more. There is something that is being used to treat covid. We have used it on two occasions and it did seem to lessen symptoms and shortened duration of COVID. It is also in official medical testing as a treatment. It is called ArtemiC Rescue and there is also an after treatment for Longcovid that is called ArtemiC Support. They have some videos on CZcams about it
This is one of the few products for Covid that has had medical testing done on it.
Shit this might be it, thank you guys, lets hope for good data!
Eureka moment me too. Best podcast I have seen on the topic i. A bit. So glad some docs continue to search!
What about us who are NOT clotting, heavy nosebleeds , gums bleeding etc
There is this condition with the word thrombocytopenia in it which basically says that as blood clots are clumping together there are too few left in the rest of the blood to do what they’re actually supposed to do. That’s one possible explanation as to what you have.
I had chronic blood clots for several months which was the first time ever in my life. They have stopped now. It was difficult.
Go check your platelet count at a lab. Low platelets will cause bleeding! Path nurse here - saw many patients with thrombocytopenia post vax. (Clots also.)
Like the fresh cut Gez, thanks again
Haha, thanks Rob!
I find it amazing (heartbreaking actually) that every time I attempt to recommend your Channel using your name to help people who are suffering from Long COVID, my Comment is immediately deleted by the YT Algorithm. Apparently it will not allow me to reference ANY external source in a Comment, be it a direct link or referring to your Channel in quotes or even more indirectly from another YT video. It’s a shame because I believe you have some of the best information on current LC treatments available on the Internet.
That’s very kind of you Andrew - yes, yt doesn’t like commenters putting in links - I think it’s because of previous issues with a plague of spam.
@@RUNDMC1 - I see some people can still do it. I believe the Algorithm has me pegged as a scammer who is trying to lure potential victims to an illegitimate site. The AI has become very good at detecting when I attempt to reference your or Raelan’s Channel, even when I’m not using links or quotes.
@@andrewstrakele6815 That could very well be. I have the same. I guess my previous use of forbidden words such as certain types of pills I have tried have put me on some sort of blacklist. You might have the same problem.
@@andrewstrakele6815 that’s weird! The channel author can usually paste links into replies, i thought it was just the commenters who couldn’t.
@@RUNDMC1 - I USED to paste links into my Conments all the time. It was my form of citation to allow any readers to see the source of the ideas. But I believe you’re correct. I did it so often, it’s likely the Algorithm interpreted it as SpamBot behavior. It started deleting my Comments with Links, so I switched to providing the author’s name, putting the Channel Name and Video Title in Quotes, and hoping the reader could search YT for it. Lastly, I’ve removed the quotes and tried to be even more indirect, but it appears the AI can still pick up I’m trying to get someone to click on another video.. I plan to test doulble-spacing the letters of your name and Channel when I make my next recommendation. 😸
Keep up the Good Work! 👍👍👍
I’m about to start this therapy… fingers crossed!
I had a d diner blood test 4858 they called it dirty blood, really struggling with long covid and it’s getting worse, really strong sweat and urine
Any body else recognise this?
If you can't feel well after everything you have done to and for yourself in terms of knowledge and treatment, there is no hope for me. I live in the States, was told I have POTs, and I can't seem to get well. I can push through if I have to with pacing, but then PEM. I'll never get through like this.
POTS is very much curable with brain retraining. DNRS, GUPTA, Primal Trust. I had it so bad I couldn't sit up without my blood pressure tanking. I am fine now. It took about 2 months of commitment to the program. Best of luck!
So... But how can we know what keeps producing it? I mean even when knowing you have this gene variant, you still would want to get down to the root cause
Each time you catch covid, and if you're jabbed, that's an ongoing issue ciz your body litterally produces the problem.
I am 66. I had covid in September of 2021. I never took a vaccine due to an allergy to flu shot. I was pretty healthy prior, but after, I fairly quickly had trouble with becoming out of breath even after a short walk. Since then, I had a mild heart attack that resolved on its own in June of 2022. I was told after much testing that my chances of another issue was low. Just this year, in late January, I had a very strange SVT that required a medicinal intervention to reboot my heart. 2 wks after that, I had an ischemic colitis that also, self-resolved before I needed intervention. Antibiotic and a wk in the hospital later, is when I found this video. All along, I have been telling family and friends that somehow, all of my issues were oddly related to Covid. No one believed me. I plan on discussing this with my GP and my Cardiologist. I am currently awaiting a heart ablation. At this time, I am on a 24 hr heart monitor because no one can seem to decide if I have intermittent SVT's or AFib. Should I bring this up before the ablation ? I don't know for sure, who to tell, or if I would even be taken seriously. PLEASE HELP ME.
currently
So sorry to hear. Do speak up, if you possibly can. You may not convince them, but it may make them more careful. Good luck.
No one seems to want to listen, but I will keep telling my story. Thank you.
Cntinued thanks Gez for your amazing work. We all so appreciate you.....
Could I get a' plasminogen activator inhibitor-1 4g/5g test' on the NHS? Would a Long Covid clinic do this?
Thanks again Gez
I’d be very surprised if you’d get this on the NHS :(
Thanks alot Gez for an interview with Jordan Vaugh. I would appreciate you interview my own long covid private Dr Osgood Named Eric oh so good on youtube. Lets say im 6x better but far far from recovered yet.
I started taking Thiamax b1 and Selenium and others.
I Believe the Thiamax b1 is helping me.
Thank you for sharing and caring for us.
Well yeah CZcams had to change their tune didn't they!!
as the truth always prevails.. .
😮 💉 💉 💉 💉😮 just connect the dots and you'll see
As a nurse in critical care, I realized the risk for thromboembolism in acute and post acute Covid-19. I took low dose ASA to reduce the risk of stroke in particular while I convalesced. Fibrin is the start of normal clotting but too much may lead to abnormal clotting.
The “triple” anticoagulant treatment is very hard. I managed just four weeks. Enzymes don’t bother me at all (12,000 fu Natto, 8000 lumbrokinase, & 1 Million units of serrapeptase daily). Would love to see some actual data regarding efficacy with LC.
Hi, curious what made you stop after 4 weeks? Glad you’re finding things that work for you now!
Yeah I’m having the same thing, but also the enzymes are affecting me differently. Nattokinase doesn’t cause so many side effects, but just a little bit too much of the serrapeptase just catapults me back to the symptoms I had last year (this has happened to me twice and it takes a couple of weeks of very deliberate and active pacing to recover from the relapses). I guess that is to say it is releasing the chemicals which caused the symptoms that are inside the microclots.
From what I gather the anticoagulant therapy doesn’t so much break down clots but prevents them from being formed, whereas nattokinase, serrapeptase and even things like garlic help break down clots.
@@ChristyCollins developed a tremor, bruising all over, bleeding in the eyes, depression like I’ve never known, to name but a few of the side effects…
@@jamiesmith4141 Wow, I'm so sorry to hear this! I'm about to start myself but am only on Eliquis. Have the enzymes been helping you at all?
@@teddybearroosevelt1847 your reply is interesting to me when you talk about releasing the chemicals. I’ve had a relapse a year and a half on after having gentle muscle manipulation on my legs. That same day the leg cramps started again. Like I’ve reactivated something :(
Question, is a treatment like this possible in europe?`I strongly suspect myself also being int his category.
I just checked in case it is in the 23andme V5 data that I have and it isn't. I think that it is rs1799889 for those looking for it. I don't know if it is in any consumer tests other than the specific one mentioned here or whole genome sequencing.
I presonally believe that MCAS is closest to the root of the issue and that the abnormal clotting is triggered by the mediators released by mast cells but of course if there is a genetic predisposition towards clotting, it will be worse.
No idea why my comment disappeared. v3 and v4 contain it as rs1799762.
@@matfax Sadly that one isn't in V5 either. Googling it also showed rs34857375 but again not in V5, so I likely won't know any time soon. But it will be interesting for people with tests that contain those SNPs to check.
Is this the same at Factor 5 liden?
@@BJ-bc7sl No this is a different mutation in a different gene.
I’m getting a result that says ‘not genotyped’ when I input rs1799762; am i understanding correctly that ‘not genotyped’ indicates I don’t have this gene?
Just how different people have different reactions to COVID, different people will have different reactions to mRNA vaccines.
Adverse reactions show up in the first week, at most.
@@patriciahoke4722 up to two years. Research doctors who have been looking into adverse affects from the jab in the States
What ICD10 code should be used for ordering the test?
Gez - can you link or at least mention the doctors, papers, and treatments that Dr. Vaughn refers to in this video? I can't figure out the correct spelling to find any information on them. Thanks!
Gez where do i source the test?
@Gez Medinger have you had either microscopy done or triple therapy in your own situation?
2:50 is the paradigm, the harder they work the worse it got...
He was saying that the symptoms would come back when they would stop thinning the blood, does this mean that you would have to constantly thin it possibly forever?
Where do we find doctors in the uk willing to help? I've basically been told to do pacing and left to get on with it. I was extremely fit with a VO2 max in the top 1% of my age now Im struggling with getting up flights of stairs or walking at any pace. Getting quite low!
I can totally understand that :(
Nattokinase seems to be effective for many, but it is downstream. What treatment does he use with patients to help with the upstream issue?
Great question. That is very interesting. I would like to know too.
Hey Gez. This is great! Thing I don't get though is that you have had apheresis and triple therapy, but neither was a silver bullet. Does that make you more sceptical about the approach? Or just more convinced of the heterogeneity of the pathology?
The latter :)
He's helping me!
I just had my first appointment with him today. UAB was useless. How are you doing now?
What does he use to break down microclotting ? Who is Jocko and what is his protocol ?
Look of Gez Medinger Jaco Laubscher Long COVID. You’ll find 3 videos.
What are some of the conditions caused by the cvd vx?
Has anyone used their mitochondrial DNA test (23andme or similar) to analyse contributing factors for Long Covid and has this helped you to improve your condition? I feel like my genetic profile should somehow reveal some answers to me but I don't have the knowledge to know what to do with it.
I wish I could help! Years ago on the Facebook Support Group there was a woman who explained how to interrogate the raw data from 23&Me. I worked out something about the CCR5 (?) gene from that. BUT...I can't remember when, how.
Can someone else help us please?!
Should patients also be tested for plasminogen activity?
What is the therapy? I am suffering from clots right now.
How do you spell the gene for impaired fibrin breakdown? Could you write it out in the description? That way we know what to be tested for. Thank you!
I was hoping to find that as well, did you find it?
Thanks for all the great content Gez. I started treatment with Dr Laubscher 34 days ago after struggling with long covid the past 18 months. I think for a lot of people suffering it is not knowing what to do. I was lucky to find out about Jaco through my CEO who knew of his treatment.
Hello. I am suffering from severe neuropathic pain following mild covid infection. What are your symptoms and have you improved on dr jaco treatment?
@@yuukielric6756I've had severe fatigue and body aches for the past 18 months. Also occasional headaches on the days I am in bed feeling fatigued. Had first acute infection end of March 2022. Body hasn't been the same since. It's been tough the last two months. Today is day 44 of treatment. Symptoms have been worse the last few weeks but I believe I should start seeing improvements in my health from day 60, around the two month mark.
Hello Chris, grateful if you could reply.
@@chriswergedo you have any neurological problems or vision problems from having long Covid?
@@hughcyboran4968 no vision issues but definitely have brain fog and forget recent events, like short term memory loss.
@Gez Medinger,
This is very interesting
What I’d like to know is this
Does this test work with someone who has been diagnosed with MGUS Monoclonal Gamothapy of Undetermined Significance?
I’m stable at the moment but have to have blood tests EVERY 4-6 months
This started 2 months after getting the first Pfizer booster.
I have had no more shots since because of IgG4 protein risk
Thanks
Jonathan
Honestly I don’t have the answer for this - sorry Jonathan!
I have found any time i have had an injury no matter if its paper cut or a slipped disk in my back those areas are where the pain is durring my so called attacks which i figured my body going on overload with inflammation to try to heal itself witch i have sveral issues like arthritis or injuries so i feel as if im being sufficated but my dr specialust in heart gastrointestinal medical physc drs gyno they are all stumped cant figure out what is wrong with im desperat i need help i get dismissed and made to feel crazy and why is it i will feel like im dying but all my vitals are reg this has been going on for over two years now and im just getting worse and worse one day i woke up and my forehead was swelled and around my eyes were blue as if i had been sufficated i get burning and stinging on the left side of my head
I had Covid 1-22, a PE in 3-22, and a residual or micro blood clot 5-23.
00:02 Genetic predisposition to abnormal clotting in long covid.
02:04 Long Covid may be a result of persistent vascular phenomenon from acute phase.
03:51 Genetic link to abnormal clotting in Long Covid
05:42 Genetic subset with issues in fibrin breakdown leading to abnormal clotting in Long Covid
07:25 Identification of abnormal clotting in healthy individuals through elevated plasminogen activator inhibitor one levels
09:16 Genetic testing for abnormal clotting in Long Covid is crucial.
10:59 Genetic differences may impact response to anticoagulant therapy in Long Covid.
12:55 Treating patients with abnormal clotting in Long Covid
14:48 Exploring fibrin breakdown in Long Covid
16:35 Importance of self-care in long-term health.
Crafted by Merlin AI.
It’s the V ffs
Nope. I'm not v'd and have had awful long covid.
Has everyone with LC had the injectable?
Nope. And most long haulers were infected in the first wave, a year before vaccines were available
It seems like it
@@RUNDMC1b.s
@@RUNDMC1 Exactly right. This guy seems to have a distinct agenda. I'd tread carefully. A little surprised you even had him on.
I got 4g/4g… what treatment do I have to get?
What is this test called on Quest diagnostics, does anybody know?
Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G
Test Code
11368
Is it Plasminogen activator inhibitor 1😏 (Pai-1)4G5G?
Is this Labcorp test the doctor is referring to?
Plasminogen Activator
Inhibitor 1 (PAI-1)
4G/5G Polymorphism
TEST: 500309
Also, will being on blood thinners (heparin) affect the results?
That sounds like the test. Not sure if heparin affects the test.
Does anyone know of any long covid clinic near Indiana ? Im miserable cant eat anything . Either i eat and cant breathe or eat and vomit 30 mins later , no energy , just sick every single day . Just not livin life at this point
Have you tried low fiber diet? Low dose naltrexone, IVIg have helped
So sorry to hear how you're suffering. A low histamine diet along with plenty of Zinc have helped me with my gut issues.
Damn, I wish he was my doc...
What genetic test?
This makes sense not sure about this guy’s an expert but even if he wasn’t whoever the experts are should be looking at that I’ve always said there’s certain people predispositions.!!!
The athletes was of course jabbed not covid infected.
No, most of his patients had the disease. He seems slyly anti vax.
Yes. Let’s look at the jab. Lots of people are and it’s not looking pretty.
@@patriciahoke4722you seem to be the sort of person who calls people names for doubting what you believe...Dumb is what i call you.
I'm being tested re d dimer, VEGF, and Von Willebrand. Do these tests show anything relevant? I wish he would have addressed the symptoms more than the demographic.
D dimer is useless for detecting these types of clots
D-dimer is rarely a good way. I'm taking natto amd anti inflammatory foods often so my d-dimer was excellent.
@@stephangauthier911 yeah I think d dimer doesn't get down to the microclot level.
Watch Gez's video interview with Dr Jaco Laubscher. He explained why D-dimer comes up negative. Basically long Covid makes the blood so sticky that there is no breakdown of the clots so no D-dimer, despite having plenty of clots.
VEGF could be quite helpful as many Long Covid patients have elevated levels. Von Willibrands possibly useful.
Eliquis helped me. My D-Dimer went from 6500 to 400. All clots in me were dissolved.
I had made the link with my previous endometriosis.. leonurine help. It’s in the Chinese medicine arsenal.
My main issue now is the tip of my finger getting thicker (cracked and hurts) and some numbness
I can't understand exactly what test he's saying because of his accent. Can somebody spell out what he said
Fairly certain it's - plasminogen activator inhibitor-1 4g/5g test
Szawacji is correct. From labcorp: Deep vein thrombosis (DVT) and coronary artery disease (CAD) are associated with increased PAI-1 levels (and likely microclots from Covid). Elevated PAI-1 levels may help predict risk of reinfarction in survivors of myocardial infarction, particularly in young individuals. PAI-1 levels tend to be lower in individuals with 4G/5G or 5G/5G genotype compared to a 4G/4G genotype. Pro tip: I know some versions of 23andme raw data have this polymorphism as G/G (5G) or -/G (4g/5g heterozygote) or -/- (4G homosygote). The rsid# is rs1799768. Ancestry may have it too. He mentions hetero carriers make 5X more and homosygotes 10X more, I dont think it is that simple. PAI-1 interacts with hormones, cytokines and other clotting genes like SERPINE that effect total levels. Actually measuring PAI-1 if you are 4g carrier probably the next step (or just direcctly measure and skip the genetic test).
@@juliemottainai6638your comment was carefully noted down for myself. Thank you very much. I can go forward w what 23 etc I acquired many yrs ago... this vid and your trustable details. Reguards from the UK
His accent is not strong.
Nattokinase, N-acetyl Cysteine, Ivermectin, natural foods with high fiber, butter, chocolate, selfheal, comfrey,
How are you today Gez?
Slow to get going!
Of course, genes play a role in almost everything. Your health, your longevity, your happiness, your personality, your intelligence, how social you are, how well you can park a car. So sure, it will also play a role in this.
There is this interaction with the epigenome though. So even someone with really strong genes can develop illnesses when exposed to chronic stress, social isolation, lack of exercise, a poor diet, etc.
My gut doesn't like Natto (4,000 FU delayed release) unfortunately. Has anyone else had trouble on it? Is it worth trying the others? Lumb and Serra? (I can't remember how they are spelt.)
And, how do we stop our bodies continually making the clots?
Maybe, these qs are addressed in Part 2? Gez?
This is addressed more in the series I made on microclotting before - note that we don’t have much science / evidence to lean on here in terms of nailing down mechanisms!
Clots are made around fibrins. Also, another Dr believes that spike proteins are not being dissolved; they become trash in the blood. So some Drs on You Tube say NAC and Bromelain taken maybe 30 minutes apart on an empty stomach, will dissolve spike proteins. NAC is an amino acid. Bromelain is from pineapple cores.
Then there is dandeline leaf extract. In another You Tube it is claimed that dandelines release about 70% of any spike proteins still connected to their red blood cells.
I take nattokeratase to thin blood and break up clots. Serrapeptase you must investigate. This powerful enzyme dissolves unused protein “trash”. It also dissolves scar tissue.
I take nattokeratase before breakfast or in the middle of the night. See videos on it. See videos on all these enzymes. Also see videos on Vitamin D3 and K2. And magnesium!
I don’t have Long Covid. But a friend of mine does so I study up for her.
If I dont trust a brand, I just use “Drs Best” brand. I think it is a brand by Swanson. I take natto with 1/2 cup of water on an empty stomach. No problems for me. Natto is just fermented soybean.
I feel seen
❤❤
Well...if that's happening, most of it has a connection to the "med", not the disease.
Can you get clots in kidneys?
Yes - every organ has a blood supply - therefore every organ can have clots.
Viral persistence keeps being brought up .. can’t make a whole replicating virus with %5 of it.. stop. Viral persistence can’t drive symptoms. Does not replicate. Full genome sequencing has been done
Former competitive bodybuilder. Very athletic background and high muscle mass.
Vaccine injury devastating.
Hm…
White and Asian? fits with my thoughts that this was designed for a certain agenda for certain ethnic groups.
Granulomatous disease and phagocyte deficiency.
What about granulomatous disease ?
I have a granulomatous disease ??????
Thanks
I think phagocytes (WBC) do play a major role in this as they do in many other viral infections like dengue fever. What really happens when you get dengue is that your WBC suddenly and significantly drop to the point that you go into comatose. I am not sure if COVID-19 would also do something similar and I don't know when the body produces sufficient WBC back if they drop. In case of dengue, it usually takes 7-10 days on average if you're lucky. This reduction in WBC in dengue happens in acute phase, I haven't read up on it long-term, but just for your information, dengue also causes a similar post-viral condition called post-dengue fatigue syndrome (PDFS) with a multitude of other debilitating cognitive issues identical to long COVID. There are published articles on PDFS.
Probiotics...😎
Dispense me with all your credentials please. We believe in no institution these days.