Cahn-Ingold-Prelog Convention (Determining R/S)

In this clip, the Cahn-Ingold-Prelog Convention is introduced, to allow for assignment of absolute configuration of stereocenters. I dunno why it took three dudes to make the convention, but it's pretty sweet if you think about it.
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HOLY FUCKING SHIT FINALLY A WAY TO ASSIGN R AND S WITHOUT CONCEPTUALIZING!!!!

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You have explained the Cahn-Ingold-Prelog convention well, my dear Prof Dave! Thank you so much!

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the fact that my profs try to make us waste our time building every molecule to assign R and S is absurd - thanks so much for this new technique, it's so much more efficient!

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No one taught me that I can arrange the molecule specially, everyone sticked to the cheat method and that confused me a lot, thank you

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For the last molecule, its easier to just change the 3D perspective than re-arrange the atoms. Simply imagine a stick with 3 balls stuck to the end, and rotating the stick makes the balls rotate with it. Now rotate it until the H-Ball is in the back, and count priority from there. Now you don't have to flip the rules, since you did not change the molecule and you still get the same answer: S.

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[@alessandrac1940]

i simply remembered 2 acronyms: ACR and TCS.. to elaborate, if the lowest priority group (usually H but not always) is away from me and i count the groups in a clockwise order, then the molecule is designated (R). If LPG is towards me and it's clockwise then it's (S). idk if that helps

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Professor Dave Explains but if they do not give where the wedge bond and dash bond is how would I know whether the hydrogen is in the front or back of the compound

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prathyush srinivasan good question, you can't! some kind of three-dimensional notation must be used to assess stereochemistry.

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watched a days worth of r/s configuration, I think this is the best method

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[@katybechnikova2821]

i know a mnemotechnic help with the r/s. if you have the substituent 4 already away, picture yourself turning a car. the molecule is steering wheel and you turn it from 1 to 2 and then 3. if your imagined car is going right, it's R, if left, it's S.

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there's also another trick it can help you guys to get the right absolut configuration which's if you've a pair number behind ( in back ) you'll assign directly ( clockwise ) if you've an impair number in back then you'll assign inversely ..

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7:40 U can flip between the other 2 groups ( right and left) as well at the same time.

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i really liked the method of orienting myself in the plane and see the structure. and get the answer quickly

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Shouldn't the original one be R? Cuz the Ethyl is to right, so H-H-H < H-H-C, like in last problem, the one with CIP convention? Please tell me if I'm going way too far from the point.

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8:15 It will be easier to make its Fischer projection and make a odd exchange and by fixing Cl then Hydrogen will be assigned furthest away from us.

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