Neuromuscular blockers - Depolarising vs Nondepolarising

Among neuromuscular blockers, we can find lot of differences between depolarising and nondepolarising agents. In this video, we will discuss differences and few of the similarities between these two types of agents.
#depolarising
#nondepolarising
0:00 Introduction
1:01 How they differ?
1:47 Action on nACh receptors
3:56 Action on muscle contractions
6:07 Action on heart
7:03 Type of block
7:47 Reversal of block
9:31 Side effect profile
10:32 7. Duration of action

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Thank you very much Sir. I understood this topic finally.

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Currently on a surgical placement, this video has been super useful. Thank you

[@egpat]

Glad it was helpful! Thank you.

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Thank you sir. It was really helpful to understand the concept :)

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Definitely, thanks for watching.

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[@egpat]

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[@egpat]

You are welcome!

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Wow super easy !!!!Thank u so much .... can u plz upload slides or pdf of these explanation ... Thanks again ...

[@egpat]

You are welcome. I will try. Thank you.

[@adityatangirala3609]

Thank you sir

[@elianaefa7431]

Nico what receptors?

[@paralleluniverse7581]

Nicotinic receptors

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thank you .

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What are directly acting muscle relaxants then?

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Thank you so much

[@egpat]

You're most welcome

[@PRIYAYADAV-nd5zm]

When the presynaptic receptor is blocked by NDMR and no AcH is released by it, then why there is tetanic fade seen with NDMR

[@pallavigovindaram4998]

Tq sir

[@arunkumarn3382]

When we used depolarising? When we used non depolarising? Please explain...

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very useful

[@egpat]

Glad to hear that. Thanks for watching

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[@arunkumarn3382]

Why we use non depolarising and depolarising drug...both are same action...both are used for muscle relaxation...why we use this two? One is enough for action... please anybody explain please...

[@egpat]

It depends on clinical setting. Most of the times non-depolarizing NMB are used, but when relaxation is required for short period and side of non-depolarizing drugs such as tachycardia are not tolerated, then depolarizing drugs are used.

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[@egpat]

Thank you very much.

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the uses ?

[@egpat]

They are mainly used as skeletal muscle relaxants during IV anesthesia.

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