Methylation, Fat Adaptation & Your Metabolism w/ Ben Lynch, ND
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- čas přidán 27. 01. 2018
- Science says eating just one meal per day can improve your health.
Learn more at highintensityhealth.com/OMAD
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Gene expert Dr. Ben Lynch helps us to better understand which flavor of genes we have and how that may affect things like food cravings, fat adaptation and hormone metabolism.
Check out Dirty Genes book: amzn.to/2GpEf7i
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Show Notes;
If you crave sugar and sweets, it’s not that you’re broken, Dr. Ben says. You may have a flavor of COMT or MAO that influences neurotransmitter breakdown and metabolism.
I think this knowledge is super helpful when it comes to personalizing a diet and exercise program that will work for you in the long term.
Dr. Lynch and I also dive into the methylation cycle and how it is involved in the
synthesis of many key molecules needed to burn fat for fuel
Hope you enjoy the convo.
Show notes and video: highintensityhealth.com/2017
He’s got a great new book out, called Dirty Genes-I posted a quick summary of that, here: highintensityhealth.com/2017
Key Takeaways:
05:21 Methylation occurs in every cell all over the body. In the brain it makes neurotransmitters.
06:23 Carnitine is required during intermittent fasting, ketosis and general fat consumption.
07:39 One sign that you are not methylating well would be an active startle reflex.
09:24 Methylation’s primary job is to turn off genes. It does turn some on.
10:17 Most methyl groups are found in protein. The cobalamins produced by gut bacteria is used only by our gut bacteria.
13:40 Stop taking folic acid.
21:24 Methylation plays a minor but significant role in detoxification.
23:49 Foods to support detoxification include cruciferous vegetables, eggs, and broccoli and radish sprouts eaten together.
27:05 If you are having high reactive nitrogen species or high reactive oxygen species, your attempts at keto will fail.
29:04 If NQO1 is not functioning well, CoQ10, vitamin C, glutathione and vitamin E supplements may do harm.
29:46 High dopamine quinone levels are found in those of us with dementia, neurological disorders, and Parkinson’s. The vitamin needed to run NQO1 is riboflavin.
32:00 Estrogen quinones lead to estrogen sensitive cancers.
32:26 Excessive levels of dopamine in your brain will lead to more norepinephrine and epinephrine.
40:30 If you have a faster COMT, eat more protein and perhaps supplement with more tyrosine.
42:00 Fast COMT/inattentive folks fidget and move to stimulate their brains to make dopamine.
43:37 Slower COMT is associated with PMS, estrogen based cancers, insomnia and higher blood pressures.
50:15 A fast MAOA depletes your serotonin levels and burns through your tryptophan.
56:34 You don’t have to be on a ketogenic diet to burn fat.
01:00:03 Excessive exercise and overtraining causes inflammation, which causes increased blood sugar, which kicks you out of ketosis.
01:03:40 The other Super Seven Genes
01:05:28 Check your arsenic levels.
01:06:20 Stop thinking disease and focus on function.
01:09:35 Every action you take cleans your genes or dirties your genes.
01:10:45 Dr. Lynch’s morning routine is one of personal growth and deep work.
01:16:00 Dr. Lynch’s desert island nutrient is liposomal glutathione.
01:17:05 Dr. Lynch’s elevator pitch: The cure for all conditions is preventing it.
I just want to say THANK YOU, because I think I finally figure out why I was super tired and depressed, and why I couldn't tolerate keto or intermittent fasting for more than 2 days, even when I'm fat adapted, and why I was always anxious and having sleep problems. I was taking high doses of folic acid (naively thinking it was neuroprotective) and my symptoms just got worse. I cannot afford a gene test but this week I decided to through away the folic acid and just eat lots of greens (mainly spinach) and beef liver. I also took a prolonged cold exposure (which makes your body use norepinephrine, depleting dopamine I guess) and the next day boom, I felt like a phoenix reborn, just awesome, and happy and euphoric. I want to say thank you again because it was VERY difficult to solve this problem (like 10 years difficult to solve it), even with positive thinking, sun exposure, exercise, HFLC diet, time restricting feeding, and omega 3 supplementation. I just love you guys, I feel you may have just save me. Please keep this great work you are doing. Cheers!
I'm 3 yrs late but better late then never. These conversations have helped me sooo much thank you
I think I've listened to this episode 4 times now and just bought the Dirty Genes book last week. Great work all around on this one!
Great, thanks Joey!
Love the detailed suggestions. Listening to Dr Ben's summit right now. Great stuff! Can't catch them all/hoping for replay sometime soon. Thanks Mike! Dr Ben I geek out on you. 😍
Lisa BH replays right now and tomorrow! then it’s done. can go forever with purchase of the Summit package if you prefer.
Amazing!!! Purchasing the book now :) Thanks so much for this guys!! Very inspirational and so, so educational 🙏🏼
This is such a blessing, thank you!!! All of it.. but specifically the bit about Tyrsosine.
I’m going to buy Ben Lynch’s book immediately. This is fantastic content. Thank you.
Thank you s much. This approach is helping me. I’ve been struggling with Keto, not losing weight, cheating more sometimes, less sometimes. Insomnia. I found the methyl b. What a difference. My appetite is way lower. I feel great. I’ll be buying your book!
I just got my 23and me results and after talking to my Dr and listening to this, everything makes so much sense now .thank you both for this Great informative video and answering questions I had 👏👌
Thank you so much this is fantastic info
absolutely LOVED his response to your elevator pitch. The cure is prevention. So true. Great interview. Thank you putting out consistently informative content.
Awesome interview really enjoy listening to Dr Ben Lynch
This video was the bomb! So much useful info! You're killin it Mike! Thanks again =D
Great interview - loved it!
Great talk, great channel! Thank you💕
Great interview!!!
Such incredible & enlightening information, thank you so so much! So much to ponder - and re the varying pms reaction due to high oestrogen and how the different responses can provide insight into our genetic type - fascinating!
what changes will you make after listening to this podcast
Another eye opening interview. I can’t wait to read his book. I totally relate to being a carb girl like Dr. Lynch, and perhaps Keto is not for me.
Excellent presentation....
Great show as always
Two of my favorite guys! Great talk and I can't wait to get the book! Enjoying the summit right now also. Mike, I listened to a podcast from a few years ago where you recommended pea protein powder. Do you still? I find I don't digest it so well, same as whey. I get bloated up. Lately I've been doing eggs and collagen in my smoothies which I like. I was doing rice protein powder but I heard there can be heavy metals in rice
INTERESTING how he stopped keto after only 6 days seems like he just hit a wall and gave up... i thought everyone was supposed hit the wall (keto flu) before they adapt...sometimes i think it takes longer for some people to adapt but sticking to it seems to give the body no choice but to adjust...i thought having carb cravings and low energy was all apart of the process until you adapt... 6 days seems like a very short period of time to make that adjustment it took me at least 2 full weeks before i reached adaptation....if he stuck with it for 2 months and still had carbs cravings and no energy then it would be a different story...but 6 days ??? thats not even a full week
I think he is “ lazy” “ cant do the work” like he says about those struggling cognitively , who arent buying his expensive , complicated course.
I have a fast MAOA also. So I can totally relate to this!
Fantastic. So very many take aways! Ordering book NOW
what were some of the take aways?
+MO JO chow mein and egg fried rice.
You have to eat leafy greens to get folate?
Beef liver says otherwise....
Beef liver is great, too!
The Vomit Exactly
Beef liver and eggs are high in folate. Can't believe he overlooked that lol.
Eggs contain only 12% folate RDA per 100g. Are you eating a kilo of eggs per day?
He said leafy greens as a vehicle for fat and non water soluble vitamins
I’ve listened to this three times it’s so useful. Thank you Dr Ben. Your book is on its way to me but can you elaborate on Folic Acid since you feel it’s so important. Any form of Folic Acid or is nutritional yeast ok?
so good....Thank you
Excellent interiew.
Mike, Amazing as usual. All these Ben Lynch interviews are huge. One mystery I've encountered during keto is that for some reason, I've developed a high BP and palps when eating Avocados. Never had issues with them before, but I tried to get them in daily to get that key level of Potassium up. Avocados also happen to have a lot of Folate in them. I think 1 whole Avocado has something like 200mcg. So I remove them, the heart palps go away and I'm beautiful. Like Ben, I'm a COMT +/+ (slow). I'm also a CBS +/+ so Folate has always been wierd for me. I've had a lot of similar stress that Ben describes (e.g. Green Tea) when trying to take a folate supplement (not folic acid). Seam to be making great gains overall on keto although at night my BP will go up slightly and make it harder to fall asleep. I have to pretty much do an Epsom Salt bath every night before bed and take 5-HTP. Otherwise, once I"m asleep, it's better quality than I have ever experienced on previous lifestyle. Always tweaking and learning. Keep the tips coming!
I have a question regarding the levodopa comment: I take velvet bean (Mucuna pruriens) powder and it has levodopa in it. Am I risking my natural dopamine production with this?
great interview and info from you both. thank you. diving into the book now, and i'm stoked! can already feel that the answers to my lifetime of myriad symptoms is contained therein. interesting that you mentioned eric braverman's protocol... years ago i went to his clinic in nyc for a full 3 day workup and his recipe didn't work for me. probably because he was not onto the dirty genes. you were both wearing what looked like hematite rings, and ben mentioned it quickly... the reference is not in the show notes and i replayed to no avail. can you please tell me what the rings are made of and their benefits? many thanks~
Guys,, a lot of theory here. My one suggestion is to remember your audience, and that to juggle all the inputs here and other shows would keep someone continually in their head about when and how to eat...
The comment about needing greens for enabling fats in Keto seems also a little theoretical. Try telling that to the many true meat and egg only carnivores who for years haven't even looked at anything green. I wonder if in Dr. Ben has ever experienced true keto adaption for any length of time to make such comments.
I will say he looks the picture of health and presents well with great listening skills and focus of delivery.
van phillips I have not experienced true keto no. Folate is needed for many processes in the body not just fuel metabolism. Blood cells, cell repair, DNA bases, neurotransmitters etc. Protein can provide sarcosine which feeds into the folate pathway. Issue is if folks have SNPs in these pathways, they can get into trouble. Some high protein folks can get away with very low folate from veggies but I doubt it’s very many. Must evaluate homocysteine MCH MCV and FIGLU.
van phillips Our audience is more advanced, hence the name High-Intensity Health.
I created this channel not for entry level or newbies, it’s more next level info for folks that have amassed basic knowledge.
Re: veggie-less diets-scientists that I’ve interviewed who have been physically present to whiteness and study the diets of modern day hunger gatherers report a wide and diverse array of vegetable intake, albeit mostly roots and tubers.
Here’s more on that topic: highintensityhealth.com/jeff-leach-human-food-project-reveals-results-of-gut-bacteria-on-a-paleo-diet/
@@Highintensityhealth Great answer. I truly appreciate when host have guests that don't dumb down information. Thank you!!!!
Hi im 33 male and fairly athletic and i've been plagued with lethargy and water retention and its up and down, but i also am always dehydrated and cant seem to get hydrated. Only time is if i do iv . i do have an mthfr snp and COMT and MOA could any of these be a reason? i have done vegan fruitarian and currently keto. I will pick up your book and cant wait but was just wondering if you would be able to give a direction in which i just head.
thanks Keep up the good work guys
Hey bro I watched a video of yours where you talk about red meat and intestinal issues (plaque) big hard bellies etc but I can’t remember which one it was....can you tell me the name of that video?
What can I say, just awesome post, thank you. Cannot get enough of listening Dr Lynch! Wish there had been time to cover more PEMT, DAO etc...Thank you so much again!
Hi Dr. Lynch, what can those of us do with premature greying (I didn’t catch the solution) - my father was also this way. Many Thanks!
thats my wondering too and i guess solution is preventing the hydrogen peroxide
About potassium, avocados would also be high in histamine right? I'll try some coconut water cause i can definitly tolerate to gain some wait if that would be a consequence...
Some say synthetic b vitamins will deplete potassium? I take Jarrows B-complex with methyl folate and methyl cobalamin, and i feel pretty good usually but if they drain potassium levels, do i have to buy a f**** supplemet? Any good potassium supplements around?
Today i had white beens for the first time in my life i think, just to get some potassium.
I usually do very well on L-dopa but tyrosine i dont notice uless i take a gram and they i get abit anxious....anything to extract from that ?
so what to do if you have reactions to the sulfur rich foods and nac (but not acetyl glutathione at 50 to100mg?
he didn't really end rise how to figure out which of the three or four variables he named might be causing them.
I found a few things to address the nqo1, but I'm curious about his suggestion there because I take vitamin C vitamin E and Q 10 and still have lots of inflammation.
Should slow COMT individuals supplement with creatine, and is there a type of creatine that is better than others for those individuals? Also, if I'm taking SAM-e in the morning and it's relaxing me or making me somewhat sleepy what could that mean? Great video, btw. Really like when the two of you make videos together. So much useful info! 🤘🏻🙏🏻 Gonna get the book.
Thanks, glad you enjoyed.
Cheers,
Mike
Roughly what hour into fasting does the body start to break down muscle for amino acids? I know Dr fung says this old protein can be rebuilt when you eat again but I’m wondering if you fast longer than 2 days if too much gets broken then built?
I’ve had sulfur intolerance for two years and take lots of molybdenum it doesn’t seem to be helping the intolerance I have not been able to eat sulfur foods or take any sulfur supplements. what do you suggest? thank you
Thankyou ,this is so important you explained what is going on in the body .
So helpful .help me .
Are life style is not good for us .
I did shift work for years it did not help me . Trying to repair .
The root of all evil greed . How much dose one really need to enjoy .
I find myself craving eggs and sulfur rich foods, but have an adverse reaction to them/ bloated, sick feeling. Eggs in particular but also now broccoli etc. I never had an issue when I was younger- it is a relatively new issue. any suggestions for things to test? or a new direction to investigate as way to remedy this?
You made me jump!
I am adrenal fatigued hypothyroid.
Been thinking of getting an HTMA test but rethinking now. I did just start Adeno by Seeking Health, and interested in the Liposomal Glutathione. Been keto since last August. It's been the only thing to help with weight/fat loss and yet others say it's harmful for AF sufferers.
Thanks for the info. I look forward to reading Dirty Genes.
Did I miss in the video where he addresses htma? did you ever get this test? also in a similar situation as you and thinking about getting it. how is keto working for you?
Did you notice anything from the Adeno B12 I'm already on methyl B12 was also thinking of adding that adeno.
Hi. How should we eat kale? Cooked or raw? I heard it’s dangerous to eat kale raw.
Thanks for another great interview, Mike. Dr. Lynch, I was curious if you have ever dealt with anxiety and higher levels of catecholamines being a compound hetero mthfr? I have these snps and seem to lean towards being more anxious rather than relaxed. Any tips for that? I have purchased and run Strategene and putting together the pieces (based on what I can understand) Also had a question re methionine snps, I see you put cocoa with a down arrow next to it and I am homo for the mtrr a66g, also down arrow. So should I stay the hell away from my beloved high polyphenol cacao nibs? :) Thanks both for all you do! I will be ordering the book to make further sense of all this. I would like it to be informative in a way that isn't stressful and leaves me feeling like a parental genetic victim. Its good to know we have a lot more control over these things!
What would be the best form of tyrosine to help with dopa production? Would Acetyl tyrosine be superior?
briiliant brilliant,,, a fantastic talk , you both are super awesome..
what about people who are overmethylators like myself and cannot intake folates/folic acid???
Is there any way you could help with the reference you made to your wife not being able to lactate well. What did Dr. Lynch recommend. My pregnant daughter is sad at the thought that she won't be able to nurse again. She pumped diligently for 2 full weeks with nothing. Hardly any milk. She tried oatmeal and .....teas....and so many things.
Hi Guys !!!!
Have you done any published research on C-60 ???
I'm drinking a kevita kombucha and have always been told that the b vitamins in kombuchas are from the bacteria in the kombucha. So I have 2 questions. I see that the B9 is folic acid, so how does that play into what you're saying about folic acid? Second question is, this says it has b12, so is the b12 from this a usable form of b12?
If it is natural b12 produced by the kombucha and isn’t listed as an ingredient added then it should be the natural useable form
Kombucha is a yeast, gave me alot of problems, be careful.
I have to admit that these days, I neglect vegetables more in preparing meals, and often end up catching up every couple of days by boiling up a plateful of mixed frozen veg, including peas/green beans/broccoli for greens (and then adding grated cheese on the top). I wonder what the HIH folks think of (1) frozen veg vs fresh, and (2) larger intakes of veg every few meals vs consistently with every meal? Many thanks :)
Chris PT Im similar to you. ai don’t have every meal. I like to switch it up. Frozen is good if reheating properly.
Thank you - relieved to know I'm in good company with this approach!
Is there a link with the electrolytes supplement taken by Dr Ben Lynch?
Brilliant!!!!
I've been doing mostly one, sometimes two meals a day in a small time window, for several weeks now, and although I'm sleeping so very much better not only am I not loosing much weight at all (75 k 74 yr old woman) my energy levels have dropped noticeably - I don't seem to be fat adapted .... I am riveted by your podcasts and I am happy that my study of diet, health and nutrition over the years have been strong & deep enough to enable me to grasp almost all of the details of human metabolism ... So I'm going to keep listening to you & try to figure out my stuckness.
I was tutoring a U3A class for several terms last year until the management committee cancelled the class due to our focus on Paleo & LCHF !!!! So sad.
I'm Australian & the MC got wind of Tasmanian doctor Dr Fekte's incredibly ridiculous and extremely damaging tangle with the Australian Nutrition Society.
Do you watch the podcasts on LowCarb Down Under ?
Margriet O'Regan seems you’re not eating enough and you’re force fasting. fasting should be easy and comfortable. if hungry please eat. doesn’t sound like you’re fat adapted. id consider eating more just keep the carbs lower and add in PQQ and carnitine
I don't disagree with Dr. Ben. Additional to his advice though I would ask you to research the effect of morning sunlight on your ability to lose weight and be healthier on a fat-adapted diet. Read "Health and Light" by John Ott. You will discover that contrary to what Opthamologists believe, you eye receives and responds to UV light which and raise your dopamine, help healing, and also restore your leptin sensitivity,, allowing you to again feel satiated by a meal. The UV light is another aide to improving sleep and increasing your restorative parasympathetic powers.
finally a smart doctor who wrote a smart book. Except for the dietary part of his book, which truthfully, many people who are led to buy his book have probably already changed their diet; which didn't work, so I found that part of the book to be redundant. However, I wish he would have went into more detail on how much of each supplement to take. A good interview, but would have been better if you broke it down into sections, as it is just too long.
Hi Mike and greetings from Eastern Washington. Long time listener and first time commenter. Love your channel and wanted to thank you for all Your great content. By far one of my favorite channels. I’m a Carpet guy by trade. Check out Mohawk’s new product called Air.O. Hypoallergenic, hydrophobic, ZERO VOC. Perfect option for us health conscious folks who still like the aesthetics of carpet. Cheers! P.S. Dr. Ben, look forward to reading your book. Thanks to you as well!
Jim Tipton awesome! good to know. what about cleaning it? trapped dust and dirt?
Dr Ben Lynch Hi Doc, thanks for the question. The airflow with this product has been demonstrated to be superior to standard Carpet. I would use a Carpet and Rug Institute (seriously, there is such a thing) recommended vacuum with a HEPA filter. Other than that I would do a professional hot water extraction per the manufacture recommendations. I could make the argument that this might be a better option than a Hardsurface product. Thing about Hardsurface is they don’t trap anything, particles just circulate around the house until their captured by an air filter. This product would act as an air filter till you come along with your HEPA vac and extract them.
No folate supplementation? But what about the study at Oxford about increased B vitamin intake via supplements reducing brain shrinkage by up to 1/3? I’m oversimplifying of course bc it’s a comment.
I’m very confused by this! I hope that someone can please explain?
I will buy the book in hopes it is covered.
Just curious on your comments about vegans or vegetarians not getting enough creatine. Doesn't the body naturally create sufficient amounts in the liver? Do you know if the the liver adapts to how much it produces based on how much creatine you get in your diet? Are there studies on this that you know of? Thanks.
Listening to this video and I was wondering if either of you have ever linked COMT (low or high) with blood type. With my studies and experimenting with family and friend's generic testing, I noticed a direct correlation between COMT (low) as type A blood, and COMT (high) as type O. Type B can be either but leans more toward the low side. Curious if you know the science behind that and can maybe send me in the right direction to learn more.
Thank you!
That's interesting. My own personal results mimic what you're saying
Noticing that coconut water in my pantry contains a substantial amount of carbs, I used it as the base to prepare kefir water using water kefir grains. This way it turned into a good source of both potassium (and other minerals) and probiotics without the excessive carbs.
I was on benzodiazepines for 7 years I came off of them and almost died. System crashed and lyme took over etc. im 3 years off of them and building my body back up but my nervous system still dosent work right. My brain dosent connect to my bowels and bladder etc etc. i was 71lbs and I’ve fasted and cleaned out my liver bowels etc im 120lbs now but seriously sensitive i can feel if power is running through the walls, shut the breaker off and i can tell. Is there a way i can get in touch with ben? Just regulating or upregulating my gaba receptors again? I have kind of weaker genes ive done genetic testing. I know it can take awhile to regenerate but I’m not sure im doing all i can. Im considering taking bpc157. Bens website is currently down?
Katie • www.drbenlynch.com/
Hi..Mike where is Dr.ben now on his channel he not updated since year
I am intermittent keto but I cycle in and out because its real life. But now I'm not sure what fat adapted means. Always learn from your podcasts. Thanks.
you are what your meat eats --- is eggs becoming contaminated? Have you heard of Anthony William -suggesting not to eat eggs? i don't agree with all of his opinions but he has described metabolic effects better than any doctor i have met
Really enjoyed this. I'm going to watch it several times! So much info😃 Where can I find more about SAMe and the cbs mutation? You said SAMe speeds up cbs? Is that Correct? So if you're cbs +/+, SAMe is probably bad?
Is NQo1 oestrogen references in the book? So fascinating
did you get any feedback
No😔
I can easily go without food for 19 -21 hrs each day, does it mean I am fat adapted? No matter how much food i had the day before? It could be that I just ate more food than I needed?
Doesn't methionine increase homocysteine though, and isn't keeping homocysteine down pretty important for people with MTHFR SNPs?
Does anyone knows what the black ring those guys were do to their health? I've noticed most of those doc,nutritionist guys all have them
Oura ring
43:40 : OMG, so true! I suspect I have a fast COMT (I took the questionnaires in Dirty Genes and "aced" it), and I do have a lot of toys on my desk, for my hands to play with: 14 poker chips, a Rubbik's cube, a chinese puzzle, a stress ball, etc. I'm constantly playing with them. Now that I think of it, no so much lately, maybe since I started taking L-Tyrosine?
Greens first!
Good Times Itms hard to argue with that advice :-)
Humans have species appropriate nutrition and we don't even digest greens. Greens are for ruminants which contain the bacteria to digest them. Humans have a gallbladder with bile for breaking down animal fats.
Greens 2nd or 3rd
I am prescribed Folic Acid to accompany Methotrexate (immunosuppressant) to treat Rheumatoid Arthritis. I am 100% committed to a LCHF lifestyle (WITH leafy greens) until I can get off these horrendous drugs. Anyone out there with tips on how to endure? New to LCHF (under 2 months). Although losing weight would be fantastic, my “why” is to heal my autoimmune disease. I am 100% committed to maintaining this way of eating beyond any health or weight goals. I’m in it for the long haul.
I am so glad I found this video! My family and I are looking closely at our genetics and trying desperately to avoid Alzheimer's Disease that runs on my mother's side of the family. My mother is in the last stage - stage 7. After uploading all of our autosomal DNA to promethease.com and comparing it to our mother's and aunt's DNA, my brother feels pretty certain that methylation disruption is one of the contributing factors in what caused her (and our grandfather) to develop the disease (obviously there are more causes than just one). None of us have the ApoE4 alleles. We have devoured Dr. Dale Bredesen's book "The End of Alzheimer's" and now we have found you! I just purchased Dr. Lynch's book, and plan to upload my DNA to his website. We also suffer from hypothyroidism which I understand involves tyrosine, another piece of the methylation cycle. Any suggestions for more literature or sources are welcome! Thank you for this video, I am so grateful to have found it. I have a degree in biology with a minor in chemistry, so I have a basic understanding and this was easy for me to follow. Thanks again!!!
Havent looked yet but what about N-acyetylcysteine?
Time restricted eating doesn’t make you go into ketosis right? Since your liver can store 2000 calories of glycogen, and your muscles even more. You never get your sugar deficiency with time restriction as I understand it.
I took SAMe before bed and got a nasty headache during the night and the next day. Any idea why that could have happened?
Also, I preordered Dirty Genes..super excited to read it😊
Jennifer Marie methylation cycle dirty likely. try niacin to counter methylation side effects.
If you are homozygous for the COMT gene, you will have issues with clearing Dopamine. SAMe produces Dopamine, so maybe you are having a reaction to it.
Mimi Cox interesting. I am heterozygous for both COMT genes
Iam Homozygous for both, and Homozyous for the MAO gene. I don't take SAMe
"Here, have some tyrosine.." 😂 more of that humour please.
i would like to order the book..
i hope it can be shipped to my country, indonesia
Agni Bonendasari check the nearest Amazon website near you. Amazon UK and Amazon Australia likely are the best to purchase it. You have a gorgeous country!
Try Book Depository. They ship worldwide without the crazy Amazon shipping rates.
Thank you Mike, Dr. Lynch? Does dirty NOS3 occur in hypothyroid/hashi and raynauld's (phenomena, syndrome, disease), and also does NOS3 function decrease when when one is fasting (always hearing about how people's hands and feet and entire body for that matter, are so cold during a fast and can this have long term implications). Where would one start their personal investigation to restoring NOS3 function, preferably without going down the genetic testing road? It would be intriguing to see if other peripheral symptoms decrease with correcting NOS3. I do have a clean diet LCHF, IF, liver support etc and on and on. Is there one path that would make sense more than others, so as not to create more problems. Curious, how did you, Dr.Lynch un-dirty you NOS3, what was your path, even though this may not be someone else's ideal path it might provide some insight? Many thanks:)
Dolores Guertin complicated process. I describe it fully in the book Dirty Genes. Lot to it.
Thank you
excellent..!
another great video, and for me.. i cant live without vegies..
this is good news for me 😅
Good quest choice. That’s one sharp, articulate cookie.
This is one of my favorite podcasts on this channel (although Dr. Gomiak is still my all-time favorite) and I just finished pre-ordering his book from Audible. If I wanted to find my own practitioner it would be someone like Dr. Lynch as you know that he could work through the various nuances that would help increase the probability of an effective and healthful end result.
I had to laugh when he had an argument with himself concerning whether his wife is flighty or not in relation to the COMT discussion. Perhaps in the future he might think about using two better set of descriptors for high versus how COMT states other than "deep thinker" versus "social and flighty". At a minimum these considerations would be better phrased as being tendencies only, but perhaps referring to them as tendencies toward introversion or extroversion would be better received by more people while still containing the information that Dr. Lynch is ultimately trying to convey.
The only comment I have on the interview was that even a 2 or 3 hour video still wouldn't have been enough. I really hope that you'll have him back for a future discussion on some topic fairly soon. Congrats to you both....
Todd Studer great points. yep. lot to cover. here are a ton of videos with fantastic targeted content. go.drbenlynch.com/fb-live-recap
Dr Ben Lynch -- I just subscribed to your You Tube site and I have already watched a number of your longer videos which have been great. Looking forward to your book as well. Cheers.
Hi, I’m new to your channel and enjoying you blogs. Being into health I just want to mention to you someone who I believe you would enjoy interviewing. My brother Malik Cotter, is a Dr. of Chinese Medicine. His practice as well as his store the Dragons Den, is on Maui, Hw. He studied in China in the mountains in the 70’s-80’s. He teaches detox classes at the college. Google him and you’ll see. Thank you and keep up all this great info.😊
Please explain about B12. If the body cannot ‘make’ something easily from commonly available foods in nature, then why do we absolutely must have it? Doesn’t nature have a way of providing us very easily with the vitamins and minerals we need without having to go out of the way to find it?
Love, love, love this interview. Great information - shared on facebook. But I thought liver had plenty of folate in it. Why only green leafy veg noted?
Julia Pace you’re right. i don’t eat liver so often forget about it.
Julia Pace - what specifically did you get out of the interview?
anything you can use?
will you implement anything said in the interview?
Yeah, liver is great for ceruloplasmin production which is necessary to make copper bio-available.
Julia Pace Some people feel the need to push plants. Animal foods are superior.
Constante carbs crave could it be parasites??
Please take this seriously I know its funny but my butt is so cold in the winter and I live way down here in Juarez México. Is this similar to the hands and feet issue?
84mvalles possibly. this could be dirty NOS3 or just losing lots of heat to the thing you’re sitting on.
Dr Ben Lynch ty Dr!! I have always asked my self what this could be. I will for sure look you up and try to buy your book I trust that you are so knowledgeable.
I think I might be overmethylated. I have depression, ADHD, food sensitivities, histamine issues, IBS, sleep problems. I don't know why most doctors don't look for it. No doctor asked to check into that. I've been to so many internal doctors for help, but just a waste of money and time. Somni wouldn't help me because I have histamine problems which can block my nose, so it would make my breathing worse, unfortunately.
Is there a Multivitamin's (Mens) that doesn't have Folic Acid? Everything I look up has it. :\
Quite possibly Mark Sisson's multivitamin. It's expensive but looks good
I'm interested to hear more about fat adapted
I am really starting to feel convinced that we all know so little that we do more harm than good. Now its folic acid - my expensive Megasorb B is full of it. Here I think I am doing myself good. I think in the end we should stay off all these supplements unless its for a short while. Now its Vit E and CQ10 as well! I cant cope with all this anymore! I also found after about 5 or 6 days I get irritable and crave carbs. I also feel better when I do intermittent fasting.
What are those black rings what those guys wearing ?
Came to get that answer too
Awesome awesome interview!! I know I am late to the party but I just have a question about fat adaptation. How can you be fat adapted without being in ketosis? I was under the impression you needed to be in ketosis in rider to be fat adapted? I am curious as I failed miserably with the ketosis diet pretty much as Dr. Lynch described, but would still love to be fat adapted. Thank you ❤️❤️
Thanks.
Check out the Live Archive playlist, lots of tips for you there.
Cheers,
Mike
It’s not low methionine that increases life span, it’s the proper balance of methionine and glycine, found in connective tissue and bones which ppl don’t eat. In other words, ppl eat too much muscle not enough of the rest of the animal.
Resveratrol. Finally I know why that supplement makes me feel yuck. Thank you!
I have a restless legs syndrome does it mean I have faster COMT?
Ana Milivojević no this is different. Could be dirty NOS3 and GST/GPX and MAOA and DAO.
I have RLS also. I assume these abbreviations are explained in the book, because I don't now what they mean. I am pre-ordering your book on Amazon. Thanks, Pam
RioStar I am going to do that also because this problem is really affecting the quality of my life
RLS has many causes. Dirty Genes does help identify why your body does things and this teaches you to be your best detective. Find the true cause not just supplement or medicate out of it. I help you do this.
Dr Ben Lynch How do I get your help?
He has a big cool ring, just like you!
That lock on your forehead is priceless
I see many familiar faces on your channel.
When we gonna see Dr. Eric Berg ?
Andy Spark forget Dr Berg...we need Dr Greger! Some real science based nutrition which would make another great interview!
Can you run on Gregor's diet up to 14 kph (8.7 mph) by using mainly fat, without depleting the glycogen storage ?
I don't think so.
I emailed Dr. Berg's team, they declined the interview...
All good!
Mike
High Intensity Health Such a shame. He did say that He was taking some timeout from interviews to focus on research and his next book. Perhaps why? But thank you for trying.
Andy Spark the Dr doesn't necessarily advocate 1 diet in terms of macros. Instead he collates research to use food as medicine. In fact one of his research pieces was on keto and he found that a plant based keto was very healthy. Basically, if you look at the work and the results of millions of research studies, a whole food, plant based diet (rich in healthy fats), protein and leafy green veg and one that has no processed/refined foods is the best for optimal health. There are a lot of parallels between Dr Greger and this channel.