DNA Repair Mechanisms Part 1

This Video Explains the DNA Repair Mechanisms That Are Mismatched Repair System (MMR), Base Excision Repair (BER) And Nucleotide Excision Repair (NER).
Link For The Second Part Of This Video:
• DNA Double Strand Brea...
Thank You For Watching.
Please Like And Subscribe to Our Channel: / easypeasylearning
Like Our Facebook Page: / learningeasypeasy
Join Our Facebook Group: / 460057834950033

[@egbejustine]

For me, it's the PACE OF YOUR VOICE that made the explanation more worthwhile.

[@EasyPeasyLearning]

Thank you 😊

[@haleemasadia5829]

this series on genetics is super helpful!

[@EasyPeasyLearning]

Thank you 😊

[@mapulenghlalele8079]

wow, this is exactly what I was looking for. Thank you so much.

[@EasyPeasyLearning]

You are welcome 😊

[@chakrithabadur1528]

It's simply super🤩thank you so much and it helps me a lot to improve my knowledge

[@EasyPeasyLearning]

You are welcome 😊

[@AsmaaKholo-ki6qx]

The best to explain genetic Biology. Very detailed and helpful to understand thank you for your videos.❤

[@EasyPeasyLearning]

You are welcome 🤗

[@emmaculateokinyi4751]

Very good explanation.much love from kenya

[@EasyPeasyLearning]

Thank you 😊

[@mohammedal-hammadi5085]

I'm so interested in these subjects and I'm really lucky because I follow your channel... Thank you so much 🌹

[@EasyPeasyLearning]

You are welcome 😊

[@srilekhamanigandan246]

Really I love your explanation 🤩really good to understand

[@EasyPeasyLearning]

Thank you! 😃

[@douglas8051]

Great explanation. Thank you

[@EasyPeasyLearning]

You are welcome 😊

[@ZeHakim]

great video thanks!

[@EasyPeasyLearning]

You are welcome 😊

[@caileightomas9501]

good summary, thanks :)

[@EasyPeasyLearning]

You are welcome 😊

[@Batman-wf1co]

Thanks you so much Sehar ..

[@EasyPeasyLearning]

You are welcome 😊

[@zubairalamkhan]

Helped a lot 🥰 Keep up the good work 👍

[@EasyPeasyLearning]

Thank you 😊

[@zubairalamkhan]

You're following "Biochemistry" by Jeremy M. Berg, John L. Tymoczko, and Lubert Stryer.??

[@EasyPeasyLearning]

This is more of Lippincott and lehninger's

[@zubairalamkhan]

ok thanks

[@liezldescallar3176]

I thank God that I found ur channel,Ican understand better❤

[@EasyPeasyLearning]

That's great. Thank you for your comment. 🤗

[@dina20031]

Thank you!

[@EasyPeasyLearning]

You are welcome 😊

[@neverlandxoxo7517]

Great explanation only one question.. doesnt mmr rely on dna pol 3 not 1?

[@lordfarquaad9887]

thank you so much
single handedly helping me not flunk my classes haha

[@EasyPeasyLearning]

You are welcome 😊

[@meghagurav6287]

Very informative nicely explained 👌👌

[@EasyPeasyLearning]

Thank you 😊

[@user-jf3ye3sw7l]

Thank you so much for this amazing explanation .Ma'am, I have a question to ask you. What is the function of DNA helicase II in NER of Prokaryotes?

[@EasyPeasyLearning]

Hi there, apology for late reply, Various DNA helicases, a group of enzymes capable of separating DNA duplex into two strands through ATP binding and hydrolysis, are required by NER to unwind the DNA duplex around the lesion to create a repair bubble and for damage verification and removal.
The reference of this statement is www.sciencedirect.com/science/article/abs/pii/S1874604723000057#:~:text=Various%20DNA%20helicases%2C%20a%20group,for%20damage%20verification%20and%20removal.

[@asea3612]

Thank you ❤❤❤

[@EasyPeasyLearning]

You are welcome 😊

[@meghachauhan6840]

Thank you🌼

[@EasyPeasyLearning]

You are welcome 😊

[@goodlifeandacademia6730]

Very well explained

[@EasyPeasyLearning]

Thanks

[@Gokukevin-786]

Do these occur in prokaryotes? Or in eukaryotes only?

[@summersummers9233]

MutS, MutL, and MutH are present in prokaryotes. The eukryote counterparts are called MSH and MLH. MutH does not have a ounterpart in eukaryotes. The nick created due to Okazaki fragments is used instead.

[@hesham-wu9ql]

6:40 that bingo is soothing sehar ❤🥰
Ur a mom now, so sry to say
Ur voice is 🎉🎉🎉🎉🎉

[@EasyPeasyLearning]

Thank you ☺️

[@nabeelsiddique5118]

That's a perfect video Madam

[@EasyPeasyLearning]

Thank you 😊

[@nabeelsiddique5118]

@@EasyPeasyLearning I will watch all your videos

[@servandohernandezgalaviz5664]

i love you you saved my life

[@EasyPeasyLearning]

Thank you 😊

[@user-px2do9bu7u]

NER
Problem : Pyrimidine dimer
Mechanism:XPC detect the damage and recruit XPD and XPB to confirm the damage
Helicase unwind DNA
XPF and XPG remove DNA
DNA polymerase bound and made a new DNA.Ligase connect everything.

[@HeshamMahrous--]

Okay,, :D

[@littlefinger8613]

When dna repair mechanism don’t function properly, is there any chance the damage cell become malignant cell?

[@EasyPeasyLearning]

Hi there, if the damage occurs on the Gene's that are going to code for cell division process or apoptosis which is a program cell death, then there is a chance that they will become malignant cells.

[@littlefinger8613]

@@EasyPeasyLearning thanks

[@EasyPeasyLearning]

@@littlefinger8613 you are welcome

[@shabnammohare9677]

Every thing all right...but we need written notes for this

[@srilekhamanigandan246]

Yes 🤧

[@EasyPeasyLearning]

Hi there, The material was taken from the book of Lippincott's Biochemistry 5th edition.

[@sunilninama8082]

Oye kirti dhang se padh lena 🐒