Why SGLT2 Inhibitors Cause Euglycemic DKA

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  • čas přidán 6. 04. 2023
  • Why are we seeing so much more euglycemic DKA after the introduction of SGLT2 inhibitors? In this video I will go over why so many more Type 2 diabetic patients are coming in with DKA when this disease process was previously much more predominantly seen in Type 1 diabetic patients. I will briefly review the pathophysiology of DKA (it's a helpful thing to review imo!) and then we will see how SGLT2 inhibitors end up playing a role to create a relative insulin deficiency leading to euglycemic DKA!
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Komentáře • 26

  • @chloesmombetsey
    @chloesmombetsey Před 8 měsíci +4

    Currently hospitalized from this. Thank you for the clear explanation.

  • @rosedean-paccagnella5820

    Nice paintings too! thanks for the explanation

  • @bfurl69
    @bfurl69 Před rokem +4

    Great video. I’m giving a presentation tomorrow on outpatient T2 diabetic meds and I got to SGLT2 inhibitors and scratched my head at euglycemic dka. Hopefully i can avoid getting pimp slapped tomorrow! 😅

  • @nina-cy5dd
    @nina-cy5dd Před 3 měsíci +2

    second year med trying to refresh on this stuff before my endocrine block. thank you! you explained that so well

  • @ericaaguilar6537
    @ericaaguilar6537 Před 2 měsíci

    Ambulatory care pharmacist resident here who is going to be presenting on weather we should or should not re-initiate SGLT2i post eDKA/DKA in patients! Appreciate the clear explanation for the mechanism :D

  • @irrelephant0
    @irrelephant0 Před rokem +1

    Really helpful! And always nice to review a little bit about DKA - I tend to always forget about it haha

  • @debigdogk9563
    @debigdogk9563 Před 11 měsíci +1

    Great explanation, it finally makes sense. Thanks Conan ❤❤❤❤

  • @chelseahylton2478
    @chelseahylton2478 Před rokem +1

    Extremely helpful!!!!!

  • @javadaghrab5687
    @javadaghrab5687 Před 11 měsíci +1

    Fantastic information I have been looking for this kind of a concise and to the point answer most of the time I get bulshit for HELP.
    I got some time on my hands I will check out the other stuff as well

  • @SourChip123
    @SourChip123 Před rokem +1

    As an M1, its cool listening to you talk through these topics. Do you think you would ever make a video highlighting paths to different fellowships after IM?

  • @chrissem2654
    @chrissem2654 Před 9 měsíci +1

    Thank you for the detailed explanation. This explanation is very helpful to understand what is going on in my body. I have just been diagnosed with EDKA caused by Synjardy to treat Prednisone indused high hba1c, which made me very sick to be admitted to the ICU. I was never a diabetic, the doctors checked my blood work for 2 years back, and there was no indication that I ever had diabetes, so the EDKA was cased by Synjardy. Thank you so much. New subscriber watching you from 🇨🇦 🇨🇦 🙏❤️

  • @malsam9668
    @malsam9668 Před 6 měsíci

    Thank you, very helpful. Watching this at my sisters bedside as she is in ICU with this now. She was on Jardiance.

    • @DuffyF56
      @DuffyF56 Před 4 měsíci

      I just got out of 4 days in ICU for EuDKA and was also on Jardiance.

  • @tiffanytran4970
    @tiffanytran4970 Před rokem +2

    Could you do a video on DKA/HHS management please? :) thank you!

  • @annaohare8263
    @annaohare8263 Před 3 měsíci +1

    Thanks helpful, from a nurse .

  • @user-tu5oy4zk4x
    @user-tu5oy4zk4x Před 6 měsíci

    well explained

  • @bruryrosally-dq9qw
    @bruryrosally-dq9qw Před 3 měsíci +2

    most article prefer the term "classical" DKA, some might prefer "typical" DKA rather than "normal DKA" to describe the most common type of DKA

    • @ConanLiuMD
      @ConanLiuMD  Před 3 měsíci +1

      Love it! Thank you for that point and for keeping me updated on the more correct terminology!

  • @MysticMango412
    @MysticMango412 Před 7 měsíci

    Hi, I was wondering which stylus and trackpad you're using for this video.

  • @LEARNING-MEDICAL-EDUCATION

    dear doctor, lets solve some drug add and abstract questions from ABIM

  • @davidalex1506
    @davidalex1506 Před rokem +2

    Inability to complete cellular respiration

  • @BsmLy
    @BsmLy Před rokem +2

    Is it possible to have EDKA although taking NO medication whatsoever?
    I hope to have a sufficient answer.

    • @rddiaz2001
      @rddiaz2001 Před rokem +2

      Yes seen it in starvation euglycemic DKA

    • @BsmLy
      @BsmLy Před rokem +1

      @@rddiaz2001 about 10 days ago, my ketones number was 8.4 while glucose was 76,.. I think I was too close.
      Any comment will help.
      Thank

  • @thomasschock4799
    @thomasschock4799 Před 10 měsíci +1

    Can you do a video explaining why athletes/active people should use a Cystatin-C test to check kidney bio markers?

    • @ConanLiuMD
      @ConanLiuMD  Před 10 měsíci +1

      I'm going to record one now