Scientists Uncover How to Reverse Aging
VloĆŸit
- Äas pĆidĂĄn 1. 06. 2024
- Scientists have successfully increased the lifespan of animals and there are first studies which describe how we might reverse aging. So how could we one day rever aging?
đŹ Subscribe for more awesome biomedical research: bit.ly/2SRMqhC
đž IG: clemens.steinek
đŹTwitter: / csteinek
In the 70s, scientists observed that cells only grow for a limited amount of days in the laboratory (Hayflick limit). Over the years, so-called hallmarks of aging have been uncovered. These hallmarks of aging govern how our cells age and we could try to slow dem down to "reverse aging".
The first hallmark of aging is mutation. We can acquire mutations by being exposed to UV radiation or certain chemicals or through cell division. Cell divsion also leads to a second hallmark of aging (telomere attrition). Furthermore, our mitochondria start to work less as quality checks do not work properly anymore.
The hallmarks of aging are tightly linked to epigenetics. Epigenetics means that we have mechanisms (DNA methylation, histone modifications) which regulate the activity of genes. Epigenetics governs the development of embryonic stem cells into cells of our body but also impact aging. The loss of mitochondria for example is linked to dysfunctional epigenetic layers. As we age, at least three epigenetic modifications namely H4K16 acetylation, H3K4 trimethylation, or H4K20 trimethylation acumulate. The thing is that epigenetics is reversible... so can we also reverse aging?
Diets have been shown to slow down (and reverse aging to a small degree). Cells also show less damages in their DNA and we find higher levels of proteins which are found in "young cellsâ. The activity of mitochondria is also increased if we undergo caloric restriction. Diets also impact the production of sirtuins which increase the lifespan and reverse aging. Different compounts (such as NMN and remodelin) have been shown to improve the epigenetic landscape which might have an effect on reversing aging. Exercise also might help to reverse aging as it helps to increase the activity of mitochondria. Meditation and having less stress also helps to increase the lengths of telomeres which might help to reverse aging. All in all studies suggests that some hallmarks of aging can be reversed so lets see where that goes!
0:00-0:46 Intro
0:46-3:53 Hallmarks of Aging
3:53-6:38 Epigenetics Controls Genes
6:38-8:45 Reversing Aging: what is known
8:45-11:25 Reversing Aging through Diets & Sports
11:25-12:13 My Opinion
References:
journals.plos.org/plosone/art...
reader.elsevier.com/reader/sd...
www.frontiersin.org/articles/...
www.frontiersin.org/articles/...
www.sciencedirect.com/science...
www.ncbi.nlm.nih.gov/pmc/arti...
journals.plos.org/plosone/art...
reader.elsevier.com/reader/sd...
www.ncbi.nlm.nih.gov/pmc/arti...
www.mdpi.com/2072-6643/12/4/1194
www.ncbi.nlm.nih.gov/pmc/arti...
onlinelibrary.wiley.com/doi/a...
Images:
Some pictures were derived from Servier Medical Art by Servier. You can find over 3000 free medical images here: smart.servier.com/
Infected cells by Beachfront, CC BY 3.0
Drosophila by Kersti Nebelsiek, CC BY 3.0
Hayflick limit by Azmistowski17, CC BY 4.0
Conrad Waddington by www.che.ac.uk/what-we-do/conr..., CC BY 4.0
Breast tissue necrosis by Calicut Medical College, CC BY 4.0
Music:
Title: Art of Silence by Uniq / uniqofficial
Title: Punch Deck by promoted by BreakingCopyright: bit.ly/bkc-ethereal2 (CC BY 3.0)
Title: Black heat by Ross Budgen (CC BY 4.0)
Title: Filaments by Scott Buckley d (CC BY 3.0)
Title: Rudolph by Lukrembro / lukrembo
Light Sting by Kevin MacLeod (CC By 4.0)
Source: incompetech.com/music/royalty-...
Title: Buddha by Kontekst
Genre and Mood: Hip Hop & Rap + Bright
Artist: incompetech.com/
About Clemens Steinek:
CLEMENS STEINEK is a PhD student/youtuber (LifeLabLearner) who is currently conducting stem cell research in Germany.
No alcohol or smoking with weight lifting and proper nutrition, hydration along with constant blood flow throughout the entire body drastically slow the aging process down.
Iâm gonna be healthy for a loooong time thenđ
don't forget about crack. that stuff is really bad for you.
My mother always looked around 20 years younger than her age. For example when she turned 60 she looked 40 and turning 80 she only looked 60 etc. However as soon as she turned "90" and only a month after her birthday, she aged 25 years in 6 months. It was unbelievable. And at 92 she looked 100. It was psychological. She said "I'm now 90 and about to die". That single thought in my opinion aged her massively.
I have the same experience. What I found is aging isn't linear, it's geometric progression
mind set counts for a lot more than ppl would ever believe. I believe if we didn't celebrate birthdays,we'd live a lot longer. Instead we emphasize on our age every years reminding us we are older. This is 1 reason I believe ppl lived a lot longer 10s of thousands of yrs ago.
@@jontherevelator9663 Yes, I think the same way. I do not celebrate my birthdays . I celebrate my perfect and eternal blessings every day.
@@jontherevelator9663 yes, I agree with you. I stop to celebrating my birthday after I turn eighteen.
She said she wanted to die so the body responded.
Iâve reversed the effects of aging in myself. I eat closer to source and avoid processed foods foreign to my body. I avoid substance abuse as well since it isnât a fundamental part of being a human being either. I also believe the mind plays a crucial role in the reversing of aging and donât acknowledge the stereotypes that society has bestowed upon itself and continues to infect itself with. For example if someone my âageâ complains and says I canât do that anymore Iâm too old. I might tell them thatâs their problem if they want to believe that because I donât. I disassociate myself with old minded people as well because Iâm not going to have that âI canâtâ mentality projected onto me. In other words if youâre âolderâ youâre probably going to preserve your youth better hanging out with younger more able minded people that arenât treating you like youâre old.
We're on the same page. The only difference is I don't drink coffee, tea (including green tea), and alcohol and I feel good for my age as a 25 year old. I'm also shocked that someone who is 10 years younger than me is getting older than me. People keep asking my age a lot because they keep forgetting that I'm 25 years old. It's an experience that no one has been through before.
I start to hang out with younger people as young as 6 years old. Kids would tell me that I fit being a child. Kinda strange.
When I was about to turn 20, I lost my college friends because I'm getting younger than they are. I end up hanging out with younger generations in college. I'm not forcing myself to hang out with younger people it just kind of happen out of nowhere. I never graduated in college I dropped out because I'm too young to be in college.
Look, my height is 5'7 and I never shrunk to a kid's height I got a little taller though. There are parts of my body I was able to reverse its age a bit, I only claim this.
@@MyFirstHandle Idk know that we are on the same page. You went right into âthe only difference isâ and mention substance abuse/use, which I mentioned so idk how well you really read what I said but I really donât care either way. Also, when I mentioned hanging out with younger people I was referring to young adults not 6 year olds. Personally my goals are about having a youthful spirit not such a childlike mind itâs the only demographic that understands me. That imo sounds like a step too far in the wrong direction.
What are the staples of your diet? As soon as I heard the video mention avoiding fat in the diet, I lost some faith in the data he's referencing.
@@asplmn Healthy proteins and fats. I believe in getting quality plant based fats such as from olive oil, nuts, avocados, etc. I use olive oil liberally. None of these videos really encompass everything I believe in. Iâve watched and read many things over the years and developed my own âprogramâ based on trial and seeing how it makes me feel and perform. The anti fat campaign that started in the late 70âs and 80âs caused so much confusion to consumers and food producers just started stripping fat out of everything and adding sugar to make things taste better. Which I definitely donât believe in. You canât trust industry with âhealthyâ food when their objective is to really get you to buy more. The brain is made of fat and many say itâs the best food for it and I really donât know why it wouldnât be.
Iâm sorry to inform you that people also aged prior to 200 years ago lol
I started exercising systematically 3-5 times/week when I was about 60. Today at 75 I exercise 3 times/week and regularly bench press 2 times 5 reps at my body weight of 75kg. I feel great and really enjoy daily life. Importantly, fitness has allowed me to recover very fast from prostate removal, radiotherapy and open heart surgery (mitral valve repair) in the last 4 years. I was never an athletic or sporty person, so you can do this. If you have old injuries (eg from sports), consult an exercise physiologist for advice on how to exercise safely. It is really worth the effort !
Not everyone is a mustang like you, imagine if you had stared early, you could have been a titan among men.
So inspiring! Thanks for sharing.
Wow! This is awesome! What an inspiration you are! Wishing you all the best!
Well done đ keep up đ
Exercise totally ages you . Read about it
The power of the mind is phenomenal, when it comes to aging. Example: Friends of mine had a dog. Absolutely bonkers. Ran around like a puppy till it died. It died at 20 years old. The thing was, no one mentioned to the dog it was old. No one explained to the dog it wasn't a good idea to chase seagulls down a very steep cliff at the beach. It fell and hurt itself and within two weeks died. If the 7 years to one human year is a rough calculation, the dog was circa 140 years old when it had this unfortunate incident. But no one had influenced the dog as to how it should feel, so it just kept going. As intelligent dogs go it was right down at the bottom of the IQ stratum, but its energy and utter joy of life was off the charts. This dog is my guru. I follow no other.
I love this example and personal story.
I concur, as well.
...ever noticed that "dog" is "god" spelled backward? đ€
If you are practiced at fasting, it doesn't "feel" like starving. In fact, you have a better idea about how your body is functioning based on your feelings. You know that hunger pains aren't really a problem. It's like getting sleepy in the afternoons, you expect hunger but have ways to push through (such as drinking water with electrolytes) the hunger pains. I've practiced fasting since I was 12 or 13 years old, and it takes a while to get used to, but once you're used to it, you look forward to that fasted feeling.
I equate fasting to doing endurance cardio activities. Longer you go, better you get at going longer.
I have Crohn's so I fast a lot to avoid pain. If I'm not doing much, I don't need much food. But if I am doing a lot of work, ill need more food.
Fasting sharpens the senses unbelievably. It's good for you :-)
The role of fats and the high intake of carbohydrates has not been properly understood by the creator of this video...
Fasting the young isn't necessary and may even impede growth
fasting isn't starvation.
"We do not want to genetically modify ourself..." yes we do, at least some. If you have a chronic genetic disease you become quite more tolerant of that thought.
Same. I have chronic bowel inflamatory disease and had absolutely terrible hemorrhages that almost killed me. If genetic modification could cure me or prevent my descendants from having it, I would gladly accept it
Iâm with you. I guess Iâm 3rd on the list now.
@@DogKacique what u eating?
@@DogKacique look into Ehlers-Danlos syndrom, alot of people have it without knowing it. I was one of them.
Yeah I'm all for genetic modification. I don't see what's wrong with it.
The apostle Paul spoke great wisdom when he said: "For me to live is Christ and to die is gain." Philippians 1:21
there is one factor you missed that im aware of, sleep. A lack of sleep is more detrimental than stress on a cellular level, on an epigenetic level, on a mitochondria level, on a nutrition absorption and waste disposal level, on a cognition level.
Im of the belief that it is probably unethical to artificially prolong life with medical intervention. healthy life habits should be the limit. My opinion is likely influenced by kim stanley robinsons' mars trilogy
People who say they don't want to live forever should still support this because you can always change your mind later but not if you're already dead. I have been saying this... longevity is our choice! If we want to sustain our health, we have to do something about it! This will start by knowing what supplies our body needs. Start by eating a balanced diet, quit vices, exercise regularly and take an NMN supplement. Mine is a 500mg per day, NMN by Vitruvin Nutrition. The goal should be to live longer while staying young and healthy. Sinclair believes that in the foreseeable future, it's possible for humans to live beyond 120 or even 150, without the frailty, diseases and disability we now associate with old age. See your result and tell the same experience.
what is nmn?
Love your video! Iâm almost 60 and spent 2019/20/22 doing the physical job of a 20 year old! The first six months were tough but then my body adjusted! I never thought that would be possible but I do have a strong mind
Aging is something that has always scared me, and your comment helped reduce my fear.
You are only as old as you feel. Don't let the numbers get in the way of productive and healthy living young person. Continue working hard and stay young and active till you drop.
Fasting with meditation feels like one is revitalizing oneself. I practice it weekly Sunday-Monday 48 hours.
Great video. I just wanted to say that regarding human diet, fat being the bad guy is no longer true. it matters which type of fats you consume, whether saturated or unsaturated. Also the lobbying done by the sugar companies to discredit fat is a big issue. Sugar, in all its forms (syrups, dextrose, maltoze, maltodextrin and even substitutes like xylitol) should be heavily regulated, yet they are in everything, from sweets to pills to salami.
Good point
Thanks for mentioning the good fats, very true and necessary for a healthy mind, heart and body.
Don't forget carbs break down into sugar as well!
Yes, Iâve read and heard that healthy saturated fats found in things like Salmon, grass-fed beef, avocados, and higher fat nuts like macadamias can increase your healthy pattern A LDL while decreasing the dangerous pattern B thereby decreasing your risks of cardiovascular disease. It also increases your production of thyroid hormone which can aid in digestion and speed up a slow metabolism. So I completely disagree with eating a low-fat diet. That is as long as youâre not consuming fats from processed seed oils.
Beef, butter, eggs and bacon! Follow the science, not flawed studies paid for by vested groups like âBig Sugarâ (is that a term like âbig oil, big pharmaâ)? Check out videos by Drs. Ford, Fung, Berry, Eckberg and Berg.
Yeah he means carbs and sugar.. at least I hope. Iâm doing Keto so fat is where itâs at.
Up until I was 30... I looked like I was 21. Now I am 36 and look 40. The last 5 years have been very stressful. I also have 6 children under 12yo. Lol
That can happen, I aged about 13 to 15 years in 1 year. Everyone I knew (outside of family) always assumed I was much younger and then I made the mistake of trying thermage became it was recommended for âmaintenanceâ by a skin care âproâ. I had 3 treatments in one year and since everyone guesses Iâm 15 years older than they used to guess. It was a huge mistake, I think the heat kĂŻlled the natural collagen (and thatâs the last thing you want to do).
@@GhostSal OMG i wanted to do it also but a lot a ppl said it melts away your fat , so now the solution for u are fillers or fat transfer , best option and based on what doctors say is to inject sculptra im about to do so but not before trying facial yoga so its up to u to decide .good luck
@@marayas7618 I would think any âheat therapyâ treatments that target and destroy fat/collagen would be ok under the chin but not on the face itself. I made the mistake of taking the persons advice when I went in for a consultation. I donât see me being able to do anything that can really fix it. I know fillers but they come out looking terrible much more often than looking good. Fat transfer too is the same problem, too many doctors arenât good at those types of things and the outcomes arenât usually good. Honestly, I think Iâm stuck with what I have. Which really makes me feel bad because I look worse than my dad and his brother (both look great and 20 years younger than they are, both donât have wrinkles or eye bags or jowls⊠the only thing they both have is gray hair and a little loose skin on their neck. Thank you for your comment and recommendations, I do appreciate it.
@@GhostSal u r welcome stay healthy that is the most important thing đ
Sincerely thanks, I am 58 and I used to pass for 35, now I am happy to pass for 45, it's catching up with me. I hope that all these innovations will come into book form soon.
Not until there's more money to be made by doing that than treating the symptoms of aging.
Which seems likely never?
Of course there could be a paradigm shift from this obviously destructive, antisocial, predatory ethos that used to be a hidden menace in society and is now openly lauded?
@@glenrisk5234 it all for a sandwich. Imagine you are a pharmaceutical company and your new drug is profitable and in wide use in the 50 to 78 year old crowd, they love it. Would you want to kill your cash cow with that drug or others? No, you would want them to live into their 90s as long as they buy your drugs and our age limitations are mostly food and drug related and if we know that in advance we can avoid those unhealthy choices that induce medical need, like aluminum in foods, mercury in vaccines WITH aluminum and well, every kind of pharmaceutical product . We need to educate ourselves and read labels to eat healthy and avoid drug complications. Good luck.
@@TheWadetube "For a sandwich"? Don't presume to speak for me. I find your pov sick. I could not bear to have the suffering of people on my conscience for any amount of money. You have no idea who I am or the life I live. That you assume I would fall in with your sick paradigm after having already pointed that sickness out speaks volumes for the arrogance of your wilful ignorance.
I'm 28 years old, growing up as a kid I always wanted to learn why we age and why my parents got old and weak. My mum has been disabled on a wheelchair since she was 37 I was around 13 at that time, that devastated my heart and till this day it does đ«đ.Now I'm starting to see myself get older and it's not nice to know that I'm no longer 21 where I didn't care about aging or anything. I researched it all my life and would love to become a professor and help young people becomes graduates in biological science. The more people want to work to eliminate disease the higher chances we will be able to achieve it. I don't want to die at 70 it's early I believe time goes quick and we age quick.
Edit: Woah thanks for the attention, comments and support people. I appreciate there are others like me. One day friends I promise a breakthrough will happen and humans will never want to look back and remember the days where their families, loved ones and friends died from diseases. â€ïž
Do you have a PHD?
If you do then you can become a professor.
Mutual feeling
@@PathWars I don't have a PHD at the moment brother. But I love this topic so much that I will not fail once I start my studies. I am hoping to travel to America in the future to learn more about it. I so wish my dream will come true and we will find a cure. See you in 2077 â€ïž
@@MRLFMAO I really hope you get to do all of that, especially bc it could help a lot of ppl. It. Hopefully it is accessible to ppl who need it.
What terrifies me the most is not death, but rather getting old - the diseases, immobility, lack of autonomy... I swear if it wasn't so against my sense of preservation, I would just end it once I start seeing the age getting in my way đ
My dad used to say about his Bday âit ainât the years, itâs the miles that take their tollâ.. I never understood that until I turned 40..
@đźđđœđ»đȘđŻđŸđŹđŽđđČđ·đȘđ»đ it kinda refers to if youâre like buying a used car and itâs not very old but has a shitload of miles on it, itâs probably got a lot of wear and tear that isnât necessarily visible.. I hope that clears it up. Iâm my part of the country we love our metaphors đđșđž
@đźđđœđ»đȘđŻđŸđŹđŽđđČđ·đȘđ»đ --Some jobs you work at will make you older. Take coal mining or how about operating a jack hammer or boxing. Professional foodball players get beat up so bad they tend to have all kinds of problems and be disabled pretty young. Work an office job, also exercise just enough and eat right, and you can probably live a long life in pretty good condition. Then, there's cigarettes, booze and drugs.
Wow, great video! I always wondered why I look so much younger than I am. No one in my age group looks as young and I don't have the health problems they do. Everything you said made me realize why. So I don't just look younger my cells really are younger! That's the best news I had all day! I will keep doing what I'm doing and live a really long time! Hopefully. đ
Cope
Another thing that helps is don't tell people your real age. There's no reason to mention it. The only time I do is to encourage someone to stop thinking they are old. Then they are shocked at how young I look. But it's best to just enjoy each moment of each day as fully as you can with no looking back!
Except right now, you'll have to worry about Klaus Schwab trying to kill you...
Yes, I would like to know more about aging slower. I said to myself that I wasn't going to put on weight and I weigh same as 40 years ago. I have maintained my flexibility. I learned Meditation 50 years ago and tai chi and the slik exercises and the Tibet rites 40 years ago. I don't eat foods that are too hard to digest (beef and pork), are too acidic (melons, most fruit), contain yeast (bread), processed food or too much canned food. I don't smoke or don't use drugs. I continue to learn new things. I enjoy examining new ideas.
i would love like to know your diet if you donât mind sharing
As we get older we start to produce less acid in our stomach and therefore we're unable to breakdown our foods as well as before and as a result we get less nutrients from our foods. I've started taking a digestive enzyme everytime I eat to ensure I'm getting all the nutrients from my diet. I'm 52 and would never give up my fruits b coz the anti-aging benefits they offer me are far too great. I consume most fruits except peaches/plums, pears and pineapples (even though pineapple contains bromelain which breakdowns protein) I don't find they are readily available where I live.... I love watermelons, mangos, apples and satusumas, they are my favourite. I put blackberries, raspberries, blueberries and kiwis in my smoothies daily.
@@pbspbs8095 Great, how can I provide you some info? P.S. My blood type is O-neg; antibiotics (only twice), anasthetic (only once), can tell when food (et cetera) doesn't agree with me, so I refrain.
@@JupiterWisdom1111 Foods react differently for different people. If anything, I have too much acid in my stomach. I cannot eat melons, love pineapple. As an O blood type, it would be difficult for me to get enough protein without eating meat.
@@deanchristie3829 The pancreas, by default, produces a lot of acids to breakdown different types of food. If you eat meat you need enough protease to break down the protein
Good video. I'm probably in the minority, but I would absolutely let myself be genetically modified to reverse my aging. I'd be first in line for that clinical trial.
I wouldn't be first in line, but I'd definitely be close to the front myself. You're not alone. Aging sucks.
Same. I don't get the worry over it as long as it's decently safe.
Count me in...
@@WickedHole Yeah i would let you get cancer before me.. psst.. Nah, but there could be side effects down the line who knows. So this anti-aging battle is in the longer run. Awesome progress!
Nature will fight back against stuff like this. It'll be great at first, and then there will be horrible side effects.
No matter how you put ribbons on it, we're all going to die. All of us a mere blink of an eye in the life of the universe.
"Each soul shall taste death". So get yourself ready for the hereafter, no escape
Ballet ..works for me .... exercises at the barre , slow muscle control exercises, balancing on one leg at a time, lots of jumping, impacts the bones....breathing correctly,, At 75 years old, young people think i am 48 years to 52 years old .... Yes I still exercise and teach 2 to 6 hours 4 times a week... Eat healthy no cook foods, No fat no oil,..I t takes discipline, determination.. calmness and.. beautiful sounds, of music heal the mind and soul..
thanks to the scientists for reversing my aging process. I used to be 40, now I am only 30
Oh, awesome! So it Decreases by 10 Years, or do you tell them the age you select to be?
I don't want to live on this planet for any longer than I have to. There's a better place out there--I'm not from here, and am happy to learn my lessons here, but the other side is my real home, where I really belong. More beauty, more love
If you eat every other day you get the same effects as fasting, but you can eat normally every other day. So it makes it easier.
I,m. Almost 70 and feel great,walk with my dogs at there fast pace every morning after lite coffee and a banana and work at a job that tests my problem solving skills every day,for diner its salmon and beets washed down by Fosters beer! I can out work kids half my age without getting winded moving large objects by hand and always avoid doctors medications-they are the killers! Having a great sence of humor really is the key! You gotta laugh to get thru this crazy world of today,if you take it to seriously it will kill you !! And besides it worked for George Burns-he lived laughing to 100 smoking cigars, life long and prosper my friends.....
.
Zeke:
I am on the same page as you đ
Working 60-70 hour weeks outside doing masonry and landscaping !
With lots of sun, proper diet, no chemicals or toxins of any kind, no pills or medication ...nothing ! haven't taken even an aspirin since I was a kid..
Keep crushing it!
Stay hard!
Well done. This presentation was not too dumbed down, yet not so overly comprehensive as to be too complicated to understand. I would be interested in another video like this that takes just a little deeper of a dive into the subject. This information has been offered many times on CZcams. I canât stand to watch the scientist who gets into concepts that require a graduate degree in order to understand. However, I would like to understand more.
I'm now 35 and I have always wondered as a kid what the point of life was if we just die anyway. Seems more things would get done if we lived indefinitely. No worries about getting old and dying would be great. Maybe our minds would focus on fixing other issues and create a legitimate heaven on earth.
imagine playing Tic-Tac-Toe forever. that is how it would feel living forever. If you live 50 years and have 3 meals a day you already eat 65.700 times, is that not enough? can't you see the hellish repetition. we all here walking around cycling throughout seven possible feelings (happiness, sadness, surprise, fear, anger, disgust, and contempt) acting like we never felt them before. Death gives meaning to life, without death life is just endlessly nothing, a never ending race, a story that keep going and going, a movie without end, a song that doesn't finish even after you are tired of listening to it.
@@newnewmee44 so then you would be given the option to leave at any time. There's a million things that could be done, invented, or traveled. Death is a curse if the body and mind are taken care of together.
Because death is not the end my friend
@@annoyingmouse1101 Death is a blessing, not a curse. No matter how damaged your body becomes, no matter how weak you become or in how much pain you are, death will set you free. Without death life would have no meaning.
Why do you think that in order for life to notbe pointless it has to last forever?
Like how do those two things even correlate?
I tell everyone Im 40 or if they are older sometimes 50, but Im not chronologically, having retired 25 years already. I didnt do anything athletic until 6-7 years ago eg never ran more than a 1/4 mi in my life and that was in HS once or twice. Most people say im mid-40s or younger but have the body (10% fat, 6 packs etc) and performance of a ripped 30 yo top athlete (I row or run 2 mi, do the hardest calisthetics (eg 15 sec front lever), full splits, etc almost daily). Before I started my reverse aging process a few years ago I really looked my age: weak, slouched over old guy with bad knee and shoulders, almost all discs herniated and more (my kids say I was a decrepit old guy fading fast). Now those who havent seen me since, see me now and many are shocked - many are speechless and demand proof Im not my son. I tell them its simple - by doing the right things you already know: eat what you need, eat better, get fit. But it isnt easy.
On diet avoid anything inflammatory - I cut out all oil and man made sugars, minimal meat, no dairy, no bakery, nothing fried, burnt or highly processed, no chemicals, no alcohol, etc. Btw: eg according to Consumer Reports most wheat grown in the US have very high levels of Round-Up, a proven carcinogen, and most rice have shockingly high levels of arsenic, also not good for you. These are not required to be reported so they are not. Add in that you need lots of fiber and you are down to eating veggies and fruit, maybe fish and have to avoid most of the typical supermarket aisles, not to mention buffets and even the usual cookouts.
On fit - exercise is really the best medicine. Even if lifespan can be prolonged, who wants to be an old aged prune? But to really reverse you need to do much much more than merely being fit, and theres no secret here: you have to workout all the time (5 to6 2-3 hours per week rain or shine), as hard as you can and as much as you can without injury. Fit means (google "fit") at least balance, mobility, cardiovascular endurance, strength and flexibility. All aspects have to be worked on, because if you dont use it you'll lose it and if you do the same things you'll get the same results. Its not what popular culture (ie movies) and most gyms portray - bulking up beach muscles to impress the girls, but really being fit.
Sadly, 99.99% of all the ones that I talked to who say they are interested in longevity and reversing aging, with living proof in front of them, and they know me, upon hearing what they have to do ie the above, balk, make excuses and simply dont have the willpower to eat right and regularly exercise hard. What they want is a magic pill and that doesnt exist and likely never will. Most say they have better things they want to do or that who knows they can drop dead tomorrow so should enjoy life while they can. My opinion is that life is about maximizing your options and you dont know until you try. Dont bother waiting for the magic pill. While you can start anytime, it does gets harder the older pass your prime you start. Im pretty sure it wouldnt take me 2 years to get a full front split if I was younger.
There was a study done concerning VO2 max. It was on police officer candidates. The higher their VO2 max, the longer they lived; regardless of other factors.
The part about exercise is also very delicate as more exercise might do the reverse process and age you more. But too little or none can age you too. How to find that balance ?
New to channel and discovered that watching this video reversed my aging process! Afterwards, I felt younger, stronger, and I just knew that it would only take an hour or so to have the energy to get up off the couch! Things are looking up! Thank you for sharing not only fascinating information, but humor.
Its what life you have,all so younger one's thing there not going too age but and dont look afere them selfs has thing thy have fore ever keep fit eat right and stress is a big facktor and thing young stay young smile more and can slow the ageing down,
Yes definitely interested for the "Aging Research" video. Thanks for sharing!
Thanks for breaking each concept in an easy to understand way
There needs to be an Apollo Program/Manhattan Project level crash program to develop life extension technology. Though first I suspect we are going to have to force society to view aging as a problem in the first place. You can't solve anything if you can't identify and define the problem.
It's the ideology. If people in general don't have an immortalist ideology then trying to seriously reverse human aging will not happen (to put it another way progress will be snail slow). A readily available example to this is the Apollo space program with human astronauts on the moon. No matter how good and beneficial such human activity is (on paper at least) if a whole lot of people don't like doing that then it ain't happening. Another example is religions if a lot of people like a particular religion and therefore a particular god(s) then it is happening it becomes popular and mainstream and here to stay.
If society becomes immortalist then a lot of institutions of society will have to change with it.
Education has to change in order to reflect immortalist ideals. Religions will have to be heavily edited and brought at the very least up to 21st century materialistic standards (ie a sentient green blob alien from the sombrero galaxy could be eligible to become Pope of Rome or woman as equal to man in the Muslim religion...there is also gender fluidity so a lot of things to discuss in order to make changes and so on). So all this hinges on "if" people in general would like doing and participating in this (unless it is forced and then obviously dystopic).
For human beings "world building" is summed up with creating children as per evolutionary mandate. While some thinking (ie to color a coloring book and you can choose any color) is required in order to accomplish that it's basically the brain on autopilot. Immortality asks more from the brain since it has to imagine an immortalist future (it's pros and cons) in the first place.
It is also kind of a paradox. If both rich and poor the king and beggar becomes immortal all of a sudden then would they still retain their social status? There are of course counter arguments against immortalism/immortality but those usually end up arguing that death (for the human animal) is somehow/someway a good thing. I personally think that the good things outweigh all the bad things so why not just do it?
For everyone who wants to not grow old, they need to be sterilized and not have kids.
@@MrGriff305 You may have a good point.
Human beings are not so good at balancing their animal and intellectual natures. In the case with immortalism what needs to be the norm is that our intellectual nature has to have primacy over our primal (primate) nature. For instance you will be able to think (cognize) to yourself to wait to have children until say when you are 200 yrs old instead of just giving into an instinct built around a limited lifespan.
FYI I'm also thinking within limited and conservative terms here.Sure you could just GATTACA the world and create a bunch of Ubermench humans however we still don't have the.. finesse (and possibly into the far flung future as well) in order to not mess things up catastrophically when dealing with DNA and for other similar genetic code based life forms. There are different paths to immortality so this should not be viewed as some set back. Cryonics (a tech work in progress), Mind upload to digital cloud (terra incognita probably requires for us to find out how the "mind" works) and good ol' cyborgs (plus more that I may have missed). I'll take the clunky old fashioned immortality.
Later on (since everyone will still be around)
with the help of technology having lots of progeny won't really matter (unless in extreme cases where you wan't to have say 20+ children). Also Laws would definitely have to come into play and DNA based organic reproduction to be heavily regulated since the same tech will make it easier to have children (ie creating your own soccer team or private army of clones). In a deathist world that we find ourselves in all that do not matter yet because of death itself. The "exit" (one could argue that it's an easy exit) that death offers will be less readily available. However on the upside there will be more of transparency and accountability.
Reverse aging doesnât mean pure immortality. The word immortality is sometimes used as an exaggeration and a saying, used in a way of saying you have an extended and very long life. Not that you canât die in an accident or something.
I will say you can not only slow down aging but stop the body and/or cells from aging altogether! Your subconscious is aging your body bc your subconscious is programmed to that and it is also programmed in your cells! So since the mind controls the body then you need to tell mind & body or cells to regenerate back in how young you want your body to be. You want to look 21 then you tell you cells get younger or regenerate back to that time. If you want to look 24, 33 or 18 then you do the same by telling your cells to regenerate at that time of your youth or if you are at that age, say to your cells to stay at the year you are currently! Here is a trick, letâs say, your 44 years young now, go back to the time in your mind when were 21 which was the year 1999, pick a month if you like & pretend you are in that time era and tell your cells to get younger to that time of you being 21 & ask them to always stay that young. Your cells will remember that time & you should feel like a tingling in your body. I believe that is your cells regenerating. Maybe you donât necessarily need to tell your cells to regenerate or get younger when you are thinking of that time because the cells will remember that time if that is your intention! But you can still ask your cells to feel more clear in your endeavor. Good luck đđ»
Age reversal is a myth. Laws of Nature ( God or Nature) are inexorable .. This kind of research is projection of mankind's (child like) fantasy for magical powers of getting what we want. After all , even the endeavours of our scientific community reflect that craving nostalgia of everlasting youth.. In the process we are uncovering and discovering some of the hidden secrets of Nature and its Laws.
This is a very interesting video. I feel that there are two vital components that have not been mentioned. First, we are all Pavlovian creatures who have been programmed by our particular life experiences, which determine all of our future choices. Often we make the same bad choices over and over again because we operate strictly from what we have learned. The important thing is to break your programming codes in order to make better stress free choices. Second, everyone carries unresolved anger from childhood injustices and we transfer that anger from the past to the present. This pattern must be broken by resolving the past anger with where it belongs. In the past. The idea is to become free of old programming codes which keep us from transforming into the present and living a more stress free life. In other words, you have to âownâ this information in order to employ it. Does this make any sense?
Absolutely cause and effect
Excellent, observation...agree with you.
I agree thank you
This video convinced me to subscribe, it's full of content on anti-aging research. Congrats.
The less you eat,without starving,the healthier you will be,simple as that
In diet, I heard to cut back on carbs, and up good natural fats. With the added 'D3', since spring, (and others) the improvement I found remarkable. ANY changes to the positive at '70 years I welcome!
PS.................IF really works also!
One of the best CZcams videos I've seen so far.
Your channel rocks! Great quality videos. :) Thanks
You are wrong about fats. Seed oil fats are bad, saturated(butter, animal fat) and olive oil are essential for cardio health.
Totally agree.
Ive listened a lot to Dr David Sinclair on this topic. Sounds promising. Hopefully we get this working on us soon rather than later.
Cool video! Thanks for covering Aging! Just found it now.
Excellent content. Thanks for sharing. Wishing to receive more informtion on these themes. Kudos!
This is great for me at aged 70 and not feeling or looking it. I've done intermittent fasting for most of my adult life - not intentionally ,but that's how I've naturally always eaten. But .... surely older people aren't really considered necessary to those in power as the world becomes overpopulated and resources become scarce? !! Also, governments do not want to pay pensions indefinitely to old people so they will not be advocating reverse ageing!
The Hayflick limit is something which actually is good for cells. Longer telomeres, surprisingly, are actually not correlated with longevity as we may think. In fact TERT mutations, increase cancer rate (and cancer cells express it at higher rates than typical somatic cells). Aging at its core can be described first and foremost really as an inevitable interaction caused by the forces of entropy.
Yes more research on this topic!!
Even the seemingly everlasting Queen is dead at 96, we all will be the same at the end no matter how much effort we try to stay young! Being happy is more important!!
I don't want to be immortal. I just want to look like I'm in my 30's when I reach 80.
Well you could become biologically immortal and when you're a hundred say "Welp that's enough" and walk off a cliff ÂŻ\_(ă)_/ÂŻ
Definitely an interesting topic.
Not to get the chance to follow science (and Sciencerely) longer and see all the fancy stuff from 2100 but also to reduce the chronic pain in the later part of our lives.
So yeah, wouldn't mind if you dig deeper into this topic :)
Very interesting topic and video. I'm interested in more on aging.
ALSO I'd be interested in learning if you have you seen any truly credible research on Autoimmune issues? ie,,, arthritis, eczema, alopecia etc ?
Very interested in all your videos especially aging, brain, stress, anxiety, food etc.
this was hard core nerdy but I super loved it & appreciate all of the information + great video as well - Tnx S
Great video! Keep the high quality content coming!
I will be back to this video in year 2100 to see if your right đŻđ
brilliant info - thank you. please continue and enlighten us. thank you !!!!!
I liked the video. Iâd love learning more from you. Thanks.
thanks for your insights, very interesting and i am sure ur channel will do well with ur great content topics!
I enjoy your combination of helpful information and sense of humor. I drink green tea and eat a lot of tofu and walk twice a day and bounce on my trampoline and have recently started exercising with some resistance bands. Also my stress levels are very low because I don't plan on dying because my plan is to be held over by popular demand. I subscribed and click the bell.
You must be young; bouncing on trampoline at 60 would make me dizzy.
Robb's stay healthy, cheers
Great video Iâm really interested in finding out more about this new reverse aging for I had no idea that it was possible thatâs incredible
Love all the aging research!
I am 60 - my biological age markers at 40 ish years of age - I look approx 46 - I do exercise daily - I take mineral supplements in preference to vitamins - I ingest and amygdaline to induce autophagy naturally - This has been known since 1950s I have intermittently fasted all my life - have found it necessary now at this stage in my life to reduce my carbohydrates and sugars - I would say I have had a natural keto diet for the last 30 years of my life - whenever I can be in control of my own food -I also bowel wash the help to get rid of toxins- I make sure I get out in nature and I meditate and have spiritual lifestyle - I still model - I do not have gray hair -You are welcome to check out some of the videos on my channels to see how I look - then you can tell me - do I look sound or behave 60?
Are you familiar with a compound called Resveratrol? Its been shown to activate Sirtuin1 and there are some interesting trials regarding longevity in model organisms. Sadly there are no large scale human trials yet and the overall situation regarding high quality studies is more like meeh...
I originally had Resveratrol in my script but decided to leave it out since (similar to your opinion) I also felt that the effects of specific anti-aging compounds in humans are largely unknown. To be fair such trials are extremely expensive as they would have to take years and there is a good chance that you lose many participants over time but it would be so interesting to know if they really a positive effect on lifespan!
The rich already have done the studies outside of normal research channels. They are quietly benefiting from it probably. With Millions and wanting to live forever? Figure the odds.
@@Sciencerely high grade THC is the key to longevity!!
I dry fast as long as possible daily, then fast further daily. Eat ketogenic refeeds, as few sweets as possible. Listen to binaural beats to increase stem cells, repair telemeres, have always had a poker face. I'm almost 73 and look 45-50, use sunscreen and good skin care products. Drink, wash, bathe, shampoo, brush teeth with baking soda & with electrolyte water always. All working so far, along with self-hypnosis for any stress, find it ore helpful than repetitive meditation. Thanks so much tho I knew most of this already.
The mind is powerful and influences the body like the old adage, " If you feel like you are old then you are."
I really enjoy all of your content, please keep it up!
The video is interesting. As a science graduate I have been deeply thinking about any scientific process that would prevent aging since prevention is better than cure. Reversal of age would indeed be a tough process and instead the clock must be frozen in such a way that certain chemical or gene modification when administered by an animal or human at a relatively younger age must totally stop the aging irrespective of the years that run chronologically. That means that a 20 year and an 80 years old individual shall look the same by appearance. This may give rise to some other problems but however no senior must go to senior citizen homes because they can take care of themselves independently like their junior counter parts. This biological advancement would give new lease of life to all and the aging or age related ailments or old and aged appearance would be a thing of past.
I think so too. That will happen in guess in some 400 years
Staying young and fit in your mind does wonders for me. I am the oldest on our premises but always volunteer the work that "should be reserved for the youngsters" That way I keep fit, alert and fast. I did discover the way to eternal youth.
1. Eat more vegetables and fruits
2. Butter and olive oil or coliner oil not vegetable or processed oil
3. Fast 8-16-18 hours per day
4. Restrict eating to 2-4 hours per day
5. Avoid canned food, processed meat, processed food
6. Avoid sugar but can have some once in a while
7. Take vitamin C pills
8. Do some light yoga, biking, stretching
9. Keep your brain occupied (always be working on a project)
10. Avoid stress
11. Keep off social media
12. Keep a few close friends
13. Breathe slower and deeper
14. No smoking or alcohol
15. Live in area with fresh air and fresh water
I just turned 60 yesterday, and it was the first birthday I did not celebrate, even paused my Facebook so as to not get birthday wishes there. The latest person to guess my age guessed it at 42...đWhen I am walking quickly somewhere, or doing jumping jacks at home etc, I chant to myself: 'Every day, in every way, I'm getting younger and younger, every day in every way, I'm getting stronger and stronger"...I think it was Tony Robbins who taught me this! Been doing it for about 10 years, along with many other things to be healthy and vibrant! It's true, 60 is the new 40!!
Great video sir. I agree with the end part of the video I could see us all probably extending our lifespan like even pass 100 but as for stop aging entirely I don't see that happening. Especially since we all know that nothing last forever in this whole planet yet alone our universe. I think I'm fine with living even with aging, it's a part of life.
Very interesting video, thank you đ€©. Just a quick point regarding fats - there's research showing that it's processed food and sugar - rather then fats - that is bad for you. However of course not all fats are equal and some - such as trans fats - are considered bad for you....
Increase your frequency and vibrate higher. thats the key...
Yes please continue this series
Interesting video. When you spoke about fats, you showed a pizza. I think most of us agree that processed high defined carbs will make us puffy, fat and age quicker. However healthy fats are essential for our wellbeing. â€đ
Absolutely! Organic and/or from grass fed cows: olive oil, butter, coconut oil, duck fat, tallow, avocado oil, walnuts...Very important! The people I know personally who have eliminated fats from their diet all seem to age quickly and become crotchety, without vitality...
Dang I really hope they bring this to market in the next 25 years.
It will be reality before 2030 no need to wait for 25 more years
Excellent video, well done & informative. I will check out your other videos on your channel.
More of this videos. Thank you.
It seems to me my aging process is a little on the slow side, Im 67 years old. Im thinking it might have to do with a clean lifestyle and working with the natural rhythms of the body: I keep pretty active all week, busy doing this and that and excercise, but I stop and rest from all that on the 7th day and allow my body to regenerate, and avoid stress. It seems to be working. I believe you can add 10 years to your lifespan by doing this.
Interesting video. It's no secret that aging can be slowed down by diet and exercise. But, as human beings I don't think it is possible to reverse aging. It is the natural life cycle of who we are. As for being immortal. Why would anyone want to live forever?
@@JoseRRodriguez I don't know. I wasn't trying to quote someone. Just sharing some thoughts.
This is a great video. The information is spot on. I am living proof
Great, keep up the research
The important thing it's to age healthy because everything needs to die eventually so others have their chance to live like we did.
There's animals that are immortal sooo
we also bout to start sending people off the planet so there's room for more, even with everyone living longer
Let's start with pets. I hate that my dogs have such short lives.
I would love more and more reverse aging. Thank You
I loved your presentation. I have been researching TCELLS. I kinda of understand some of this, but hard to find information. I am now subscribed to your channel. Thank you please recommend books to study
Great video, your presentation is friendly and informative. I enjoyed it a lot.
how much fasting?
ketosis for 1month every year?
does weather affect anything?
Thanks, would like more!
Thank you for the information
It's probably more important to focus on staying away from the things that accelerate aging like refined sugar (Which is in almost everything) and processed food which should have warning labels. Because the fact is you can't really reverse aging, unless a man is really as old as his arteries in that case maybe you can.
I am a late bloomer. Now at age 67 I'm thinking about settling down and starting a family.
Kya kiya jaye aapka
Thanks for the great explanations.
TQ Great And Useful Topic Thanks Once Again
Or you could just prevent aging through diet as the 80 year old Annette Larkins did. Stress kills and causes aging and the proper diet and lifestyle aimed at physiological stress reduction works better than pills.
what was her diet?
we're not mice, we have much longer life spans and the trajectory of cell regeneration is different. Taking the mouse model for longevity and applying it to humans can be a huge mistake.
Thatâs why they havenât yet, they are taking time to better understand it
Very interesting...as knowledge increases our lifespans will also increase..
Great! Thanks for the information