HIV and AIDS
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- čas přidán 27. 07. 2024
- Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV),[a retrovirus.Following initial infection an individual may not notice any symptoms, or may experience a brief period of influenza-like illness. Typically, this is followed by a prolonged incubation period with no symptoms.[5] If the infection progresses, it interferes more with the immune system, increasing the risk of developing common infections such as tuberculosis, as well as other opportunistic infections, and tumors which are rare in people who have normal immune function.[4] These late symptoms of infection are referred to as acquired immunodeficiency syndrome (AIDS).[5] This stage is often also associated with unintended weight loss
The initial period following the contraction of HIV is called acute HIV, primary HIV or acute retroviral syndrome.[27][28] Many individuals develop an influenza-like illness or a mononucleosis-like illness 2-4 weeks after exposure while others have no significant symptoms.
After the virus enters the body, there is a period of rapid viral replication, leading to an abundance of virus in the peripheral blood. During primary infection, the level of HIV may reach several million virus particles per milliliter of blood.[101] This response is accompanied by a marked drop in the number of circulating CD4+ T cells. The acute viremia is almost invariably associated with activation of CD8+ T cells, which kill HIV-infected cells, and subsequently with antibody production, or seroconversion. The CD8+ T cell response is thought to be important in controlling virus levels, which peak and then decline, as the CD4+ T cell counts recover. A good CD8+ T cell response has been linked to slower disease progression and a better prognosis, though it does not eliminate the virus.
Amazing lecture.. ❤.
Nice
1:15 The co-receptors are CCR5 and CXCR4, but not CXCR5.
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Really underrated
Glad u think so...
Shabir, Superb review! Excellent illustrations and video.
Those viruses are so clever. Does anyone know why we even have viruses?
thanks Dr Mike ✌️
@@hussainbiology if you ever figure out the why you'll win the Nobel prize.
@@michaeleisenberg7867 Ah... that is aspiring
❤️👍
I m also life science student
My exam on 26 march
I m so afraid about clear it plz guide