Imaging brain tumors - 4 - Other low grade gliomas
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- čas přidán 24. 07. 2024
- Brain tumors are one of the most common diagnoses addressed in neuroradiology. This covers a wide spectrum of disease, from primary brain tumors like gliomas and glioblastomas to secondary disease like metastases. This lecture covers the spectrum of the most common brain tumors, with an emphasis on primary brain tumors.
This video discusses imaging and genetic features of some less common low grade tumors like pilocytic astrocytoma, dysembryoplastic neuroepithelial tumor (DNET), ganglioglioma, and pleomorphic xanthoastrocytoma (PXA). These tumors are often seen in younger patients, many of whom will present with seizures. Surgery is often curative. There is a lot of imaging overlap for these tumors, especially DNET and ganglioglioma, which can appear very similar. However, the specific diagnosis is less important than knowing that a lesion may be a low grade glioma.
Additional videos in the playlist will address the imaging findings of other types of brain tumors.
The level of this lecture is appropriate for radiology residents, radiology fellows, and trainees in other specialties who have an interest in neuroradiology or may see patients with brain tumors.
Check out this video and additional content on www.learnneuroradiology.com
Thank you for posting and helping me out with the lesson reference.
Glad it was helpful! Enjoy the rest of the videos!
Getting an investigation done via CT, personally I think its a liver problem causing symptoms but worth ruling out things. The development of various imaging technologies is just incredible, MRI probably being my favourite.
MRI has truly revolutionized medical care, particularly in the brain, where it was previously just a game of interpreting small clues based on symptoms.
Thank you for doing this!
No problem! Thanks for checking out the videos
I'm glad for this video. It explains more than lots of multiple site research. 1 website said that a GG happens to children and young adults, up to 21. (Which I liked a better precision of age than saying "young adult.")
But I gave a more open allowance of say "25" and this vid agrees no more than 30. Just I have GG I'm almost 40. So just wondered if I should focus more on Adult "grade 2" over Juvenile "grade 1" Tumour research. And I should.
Plus it'll make sense why most paper work says "low grade" not "juvenile"
Thank you ☺️
Yes, there are a lot of different low grade gliomas. Most have a predilection for young patients, but not always. You can see pilocytic astrocytomas well into adulthood. Better to think about them as well-circumscribed low grade gliomas regardless of age. Thanks for watching!
Great.
Thank you. My son has a PXA tumor and there really isn't a lot of information out there. Are there common symptoms or after effects or prescribed treatments
I'm sorry your son has a tumor, and I'm sure that is very frightening.
It really depends on a number of things, including the size of the tumor, location of the tumor, how it is treated (surgery, radiation, chemotherapy, or a combination), and many other factors. You probably need to sit down with your son's doctor and have a realistic discussion about your questions. They should be able to help answer them.
What are some options for seizure control when the DNET is deemed inoperable and she has failed more than 3 meds for seizure control.
This is going to depend on the individual patient, but if medications are not working there are other options for tumor/seizure control such as laser ablation, responsive neurostimulators, vagus stimulator, deep brain stimulation, and others. It really requires thorough evaluation by a solid team of neurologists and neurosurgeons to work out what the best options may be.
Thank you is helpful
You're welcome!
Great Video. what is the difference between a collection of abnormal tissue and a tumor?
This is a great question. Essentially nothing. A tumor IS an abnormal collection of tissue that often displaces the surrounding tissue. While most people associate the word tumor with aggressive cancers, tumors can be benign (not growing that fast) or malignant (rapidly dividing or increasing in size, likely to spread).
There is a pretty good definition on the NIH web site here:
www.cancer.gov/publications/dictionaries/cancer-terms/def/tumor
@@LearnNeuroradiology Thanks very much. My nephew who is 24 years old has a slow-growing tumor that was just identified from seizures. They were able to see the cells on an MRI he had when he was 13 due to headaches and see it is very slow-growing. It's been a terrifying time for us and I am trying to learn as much about this as I can. Your video was excellent. Thanks so much! Grateful for your response.
It was just found through a MRI of my brain, that I have a brain tumor,..was told most likely benign. How urgent is it to see a neurosurgeon and what timely manner to be seen? I need to know ASAP, because it seems that there’s no concern as to how soon I need to see a neurosurgeon. I’ve already lost some eyesight in left eye. I have uncontrolled blood pressure,. Vomiting, headaches, and I had an incident of my right leg going totally numb!
I'm sorry to hear. I think you need to talk to your doctors about when to see a neurosurgeon. It also seems like you have other issues to deal with urgently too, like the blood pressure. I'd talk to your doctor ASAP.
be well, Janet. You will pull through
Thumb it up
Definitelly helpfull, but if I may add constructive criticism, your voice is too low! Maybe try to speak a little bit louder. Thanks!
Thanks watching the video and the comment! I definitely have been trying hard on the newer videos to have better quality audio.
My 32 year old brother passed away last 4 months due to this life threatening High Great Glioblastma disease😭😭
I'm sorry for the loss. Thank you for the comment.
How long do u have to wait for surgery once they find a tumor?
You don't have to wait at all. Mostly it depends on how severe the symptoms are and how aggressive the tumor looks.
@@LearnNeuroradiology ok thx
I have seizure disorders, head ache, loss of balance, recently diagnosed with Bilateral optical disc edema... I afraid 😔
I'm sorry to hear that. It sounds like you should talk to your doctor about what might be causing it and how to get the best treatment. Good luck and I hope you feel better soon.
Can you disfribe your balance problems
What does the DIPG tumor look like?
DIPG, or all the midline pontine gliomas, tend to occur in younger patients and are expansile, FLAIR hyperintense masses mostly in the brainstem. They may enhance less than GBMs and look more like grade 3 gliomas with patchy enhancement. However, they have very poor outcomes.
Maybe we can try to cover in another video.
Hello, I am going in for an MRI, I have had a persistent heaviness in my head for about 3 years. Any chance it could be a tumor?
There are a lot of things that can cause heaviness in the head, and most of them are not brain tumors. I recommend that you see a doctor though so you can talk about your concerns.
@@LearnNeuroradiology Thank you for your input, I have not gotten the results back yet but hopefully it's nothing serious🤞
@@rayyanimtiaz3792 what was it?
@@pawepetek7294 they say a lot of patients are coming in with the same issue, they diagnosed me with NDPH, New Daily Persistent Headache. They said I was completely healthy and had no issues whatsoever. It brought me a huge relief, however there is no cure for NDPH at the moment. Let me know more about your situation.
@@rayyanimtiaz3792 bascially I suffer from severe health anxiety because my sister was diagnosed with Hodgkin's Lymphoma back in 2015. I'm also diagnosed with hypochondria so I'm sure I have some illness. Now I've been scared about brain tumor for the past 4 months. Back in February I got a massive headache and it really worried me. Since then I didn't get much headaches but I have this weird discomfort in the back of my head on the left side. It doesn't really hurt or it hurts really weak. I check my balance, my vision, my reflexes and other neurological things every day. I scheduled an MRI just to be sure I don't have a brain tumor. It's this Monday. I'm really stressed I have a glioblastoma or some other serious tumor. I just hope my results are normal. Hope you're doing well.
Great videos. Any chance you could improve audio/recording?
Thanks for the feedback.
Can you be more specific about what's bothering you about the audio? Is it the volume? pitch? just general?
I'll do my best to improve the audio. I did change microphones at some point recently, so hopefully that improved things. Do you have similar problems with all the videos or is it better on newer videos, like:
czcams.com/video/zf4WVPeZlg0/video.html
@@LearnNeuroradiology I think it may be related to how close you are from the mic, it sounds kind of too close for me. Thanks for the content! Greetings from Chile :)
I'll do my best to make it as good as possible! Thanks again!
Survival rate and recurrance of pxa tumors???
For brain tumors, quite good. Numbers vary, but 5 year survival of 75-80% and progression free survival of probably 60-70% (meaning the 5 year recurrence rate is 30-40%).
The following references provide more details:
www.ncbi.nlm.nih.gov/pmc/articles/PMC4400218/
www.ncbi.nlm.nih.gov/pmc/articles/PMC3730029/
LearnNeuroradiology thank you for the quick response. I was recently given a partial report of my pathology. They told me it was a pxa but could not yet speak to if it was grade 2 or 3. Golf ball and a half in my right front lobe. Total resection on June 19th and another craniotomy exactly 3 weeks later to install a catheder to relieve some fluid build up.
I'm sorry to hear that you have a tumor. It can sometimes be hard to to grade the bad features of the tumor so it can take extra time. Sometimes they may not be able to tell at all because they are pretty rare tumors.
Best of luck with your treatment and follow-up and thanks for checking out the video!
you sound like corpse
Dude needs a cough drop or a check up with a ent to check his throat😅
Sir can non contrasted CT scan shows the tumours on our brain. Tell me sir.
Dude I already answered you on the other video. (video 2)
Poor voice. Very thick n low vol
thank you but can you speak up? I can barely hear you
I've tried to improve the quality over time. Hopefully the later videos are better. Thanks for the feedback
Worst vocal fry EVER
My head is killing me and I'm only 21
I'm sorry to hear that. A lot of people have headaches unfortunately, but luckily most of them aren't caused by brain tumors. I suggest your talk to your doctor and possibly see a headache neurologist. Good luck.
Please speak louder difficult to understand for non native people
I'll try to do better on the future videos. Part of it is just my voice, which is naturally low.
what happened to your voice...not clear
You might want to have your throat checked out. 😳
Everyone comes for their free medical education and pays with free medical advice!
In reality, you might check out some of the later videos, as the sound is better.
Please speak clearly!
It's not like I was TRYING to make an unclear video.
I do think I have improved the quality over time so check out the later videos.
Why is he talking like that, he needs to speak more clearly !!!!!!!!!!
Dude if you really make a video at least speak clear.Disturbing voice.
Dude if you really make a comment at least find something original to say