How to spike impurity for preparation of precision samples during RS validation?

Preparation of test solution having level of impurity at its specification may demand for external spiking of suitable impurity stock solution into test solution. This video will explain you how to prepare method precision samples during RS method validation

[@GameDRx]

Grt job done in simple manner

[@najibsust]

You are my pharma Guru

[@chodipallimasenu6792]

Very useful information

[@verans7152]

Good and great explination

[@Ajaythakurhappy]

Very useful sir 👍

[@gangadharm1983]

Suprbb explanation sir

[@utkarshvyas3185]

Nice explanation ..

[@4fourty242]

Good explanation👍🏼

[@achyutjagdhane9683]

thanks for videos

[@sravanie1235]

Thanks sir

[@sambhajimasal4248]

as usual,1st view

[@baderbassam8533]

You can help us, how we calculated the spike sample after inject

[@ankitmaurya9198]

Sir if impurity presents in samples at Loq level can't spike or not?

[@nitinbhoir5339]

What about impurity potency

[@gopalrajput4700]

Percentage to ppm, how
Is it, 0.5*10000=5000

[@bestdancevideos2253]

HPLC And GC Column Chemistry Sir
Please Upload

[@ShoaibKhan-uk6dq]

When v calculate accuracy, accuracy is failed, spiking should be done at 5 ppm not 3 ppm

[@sarakhan4454]

Sir hoe 0.5 percent equivalent to 5ppm? Not understand.
0.5 percent equvalrnt to 500 ppm
May i right or wrong cant understand

[@sanketgentalwar1082]

Sample is 1000 ppm congratulations means it's a 100% and it's 0.5%. Is 5 PPM

[@praveensharma5688]

Sir i have a concenrn, i don't understand that ..( 0.2% equals to 2ppm).how is possible, because 1% equals to 10000ppm.....so please clearify.

[@sarakhan4454]

Yes same question? Its equivalent to 200 ppm

[@sanketgentalwar1082]

Sample is 1000 ppm and it's 0.2% is 2PPM