How to decide the concentration for the sample and standard in related substances?
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- čas přidán 26. 04. 2021
- How to set the concentration for the sample and standard in related substances?
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1. Assay method validation mastery
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» Preparation of conc. matrix, protocol, calculations, report wrt global requirements
2. Dissolution method validation mastery
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» Preparation of conc. matrix, protocol, calculations, report wrt global requirements
3. Related substances method validation mastery
» Everything you need to know to perform RS validation
» Preparation of conc. matrix, protocol, calculations, report wrt global requirements
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» Preparation of conc. matrix, protocol, calculations, report wrt global requirements
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» Concentration matrix for method validation
» Confirmation on selected weighing and dilution details
» Mapping expected concentrations for API/Impurities
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» Reporting and rounding of analytical results
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yours videos are highly appreciable and useful...thank you lot
Plz make video on "How to develop method from a given molecular structure"
Very worthable vedio to me. Tq sir.. Please educate like this way with more vedios
Cleary understood ....how to set standard and sample concertration... Thank you.........
Thanks Sir, it's new for me. Thanks for upgrading....
ur explanation is very good thanks sir
Hi Bhaskar sir, this is the first ever channel which is providing enormous knowledge to our pharma professionals. God bless you and your family 👌❤
Thanks a lot
thank you , it is very helpful
Thanks sir very good keep it up work
Thank you very much sir for such support
very good explaination sir
Sir thanku for ur valuable information
It's nice explaination..
Easy understanding
Sir, your all vedios are knowledgeable and helpful 🙏🙏
So nice of you
Very helpful
Good videos sir..
Thank you sir it's nice vedeo
Thank you so much sir
Thank you for describe
Dear sir, First of all thanks for helping me to improve the knowledge. In this class I have one small doubt sir, I am not understand to set the concentration of standard clearly sir
Standard concentration is set according to the specifications of the highest unknown specifications impurity for eg. Unknown impurity specifications are 0.2% and sample concentration is 1000ppm simply cross multiplication we will get standard concentration.
Thank you sir
Very good
Pls mk vdo on how to rectify process and degrade impurity if possible. Thnk you!!
I am hapy to you,thank you very much sir,your vedio was very useful for whom studying drug analysis by HPLC
Sir i need to how to calculate for LOD and LOQ in both sample and standard drug and formulation using HPLC with perfectly
Thank you sir
Great
Thank u sir
Thank you
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Perfect
Thanks
where 1ppm come from and how did find SN 10. please not clear
Sir why prepared std concentration in unknown level? And why must be our reporting threshold with inthe
Sir how to fix limit for dissolution of tablets or capsules dosage forms???
Nice
sir I need to know use of buffer compostion and its pH? WITH SOLVENT
informative
Good video
Please make video on RS qualifications techniques
Rs quantification techniques
Pl make different video of method development Related Substance..
Very well explained
Glad it was helpful!
@@pharmagrowthhub3083sir.... requesting you to make vedio on Analytical method development
Reply sir
Excellent sir
Sir Plese make video on how to start analytical method development for new molecule
So nice of you
Sir, What is chart purity?
How decide sample conc in assay?
Sir why taken standard concentration higher unknown impurity %
Sir, Can you elaborate how 1ppm = 0.025 percentage
I think that is 25 ppm right
There is very simple calculation,
Impurity LOQ in % /100 × Sample Concentration in ppm = Impurity in ppm
0.025/100× 4000= 1ppm,
Note: above calculation I used 100 because your Impurity LOQ in %, hence
Example:
Assay in % : mg per mL / Labled Amount × 100 = content in %
RS sple concentration in API afyer method set
Can somebody tell me how 1ppm equals to 0.025%
Sir, please take lecture on isolation of impurities by Preparative HPLC and it's profile topic.
Sir plz translate in hindi
Sir you can't explain proper
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