Fatty Acid Synthesis in Plastids

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  • čas přidán 2. 06. 2024
  • The plastidial fatty acid synthesis requires acetyl-CoA, ATP and NAD(P)H as substrates, and multiple routes exist to provide these substrates, although the relative importance of these routes depends on the sources of plastids.
    Fatty acid synthesis in plastids occurs mainly in plants. Plastids are specialized organelles found in plants and algae that play important roles in many metabolic processes, including photosynthesis and lipid synthesis. This is called de novo fatty acid biosynthesis or fatty acid synthesis. It occurs in the matrix of the plastid, specifically in a structure called the plastid envelope. The plastid envelope has an inner and outer membrane that separates the matrix from the cytoplasm. Acetyl-CoA is produced from a variety of sources, including pyruvate from glycolysis, the breakdown of fatty acids or amino acids via beta-oxidation. The cytoplasm enters the plastid and passes through the two membranes surrounding the plastid. Coenzyme A (ACC). This step is the rate-limiting step in fatty acid synthesis and is highly controlled. In plants, this complex involves several enzymes that work together to add two carbon units from malonyl-CoA to a growing chain of fatty acids, commonly known as palmitic acid (16:0) of 16-carbon saturated fatty acids. This process involves repetition of synthesis, reduction, dehydration and reduction reactions, and finally extension of the fatty acid chain. Producing different types of fatty acids according to the body's specific needs. Acylglycerol (TAG), which is an energy store in plant seeds and other organs.

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